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Therapy: Corticosteroid Therapy

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Total 6881 results found since Jan 2013.

Intranasal Corticosteroids Tied to Less Severe COVID - 19 Outcomes
Findings seen among individuals regularly using steroid nasal sprays before COVID - 19 diagnosis
Source: Pulmonary Medicine News - Doctors Lounge - October 2, 2021 Category: Respiratory Medicine Tags: Family Medicine, Infections, Internal Medicine, Allergy, ENT, Pharmacy, Pulmonology, Journal, Source Type: news

Severe acute asthma at the Paediatric Intensive Care Unit: can we link the clinical phenotypes to immunological endotypes?
Expert Rev Respir Med. 2021 Oct 28. doi: 10.1080/17476348.2021.1997597. Online ahead of print.ABSTRACTINTRODUCTION: The clinical phenotype of severe acute asthma at the Paediatric Intensive Care Unit (PICU) is highly heterogeneous. However, current treatment is still based on a 'one size fits all approach'.AREAS COVERED: We aim to give a comprehensive description of the clinical characteristics of paediatric patients with severe acute asthma admitted to the PICU and available immunological biomarkers, providing the first steps towards precision medicine for this patient population. A literature search was performed using P...
Source: Expert Review of Respiratory Medicine - October 28, 2021 Category: Respiratory Medicine Authors: Sarah van den Berg Simone Hashimoto Korneliusz Golebski Susanne J H Vijverberg Berber Kapitein Source Type: research

Biologics in Asthma: A Molecular Perspective to Precision Medicine
Recent developments in therapeutic strategies have provided alternatives to corticosteroids as the cornerstone treatment for managing airway inflammation in asthma. The past two decades have witnessed a tremendous boost in the development of anti-cytokine monoclonal antibody (mAb) therapies for the management of severe asthma. Novel biologics that target eosinophilic inflammation (or type 2, T2 inflammation) have been the most successful at treating asthma symptoms, though there are a few in the drug development pipeline for treating non-eosinophilic or T2-low asthma. There has been significant improvement in clinical outc...
Source: Frontiers in Pharmacology - January 19, 2022 Category: Drugs & Pharmacology Source Type: research

Brazilian guidelines for the treatment of outpatients with suspected or confirmed COVID-19. A joint guideline of the Brazilian Association of Emergency Medicine (ABRAMEDE), Brazilian Medical Association (AMB), Brazilian Society of Angiology and Vascular Surgery (SBACV), Brazilian Society of Geriatrics and Gerontology (SBGG), Brazilian Society of Infectious Diseases (SBI), Brazilian Society of Family and Community Medicine (SBFMC), and Brazilian Thoracic Society (SBPT)
CONCLUSION: To date, few therapies have demonstrated effectiveness in the treatment of outpatients with COVID-19. Recommendations are restricted to what should not be used, in order to provide the best treatment according to the principles of evidence-based medicine and to promote resource savings by aboiding ineffective treatments.PMID:35341739 | DOI:10.1016/j.bjid.2022.102347
Source: Braz J Infect Dis - March 28, 2022 Category: Infectious Diseases Authors: Maicon Falavigna Karlyse Claudino Belli Alexandre Naime Barbosa Alexandre Prehn Zavascki Ana Catharina de Seixas Santos Nastri Christiane Machado Santana Cinara Stein D ébora Dalmas Gräf Flavio Adsuara Cadegiani H élio Penna Guimarães Jos é Tadeu Mon Source Type: research

Asthma in Adults May Raise Risk for Subsequent Obesity
Higher risk seen for those with nonatopic disease, longer disease duration, as well as those taking oral corticosteroids
Source: Pulmonary Medicine News - Doctors Lounge - October 12, 2017 Category: Respiratory Medicine Tags: Family Medicine, Internal Medicine, Allergy, Pulmonology, Journal, Source Type: news

Amniotic dehydrated cell and protein concentrate  versus corticosteroid in knee osteoarthritis: preliminary findings
Regenerative Medicine, Ahead of Print.
Source: Future Medicine: Regenerative Medicine - May 19, 2022 Category: Genetics & Stem Cells Authors: Oluseun Olufade Giorgio Negron William Berrigan Benjamin Sirutis Jeremy Whitley Kirk Easley Yunyun Chen Kenneth Mautner Source Type: research

Comparison of the characteristics, morbidity and mortality of COVID-19 between first and second/third wave in a hospital setting in Lombardy: a retrospective cohort study
In conclusion, our data suggest that earlier diagnosis, timely hospital admission and rational use of the therapeutic options reduced the systemic inflammatory response and were associated to a better outcome during the 2nd/3rd wave.
Source: Internal and Emergency Medicine - July 9, 2022 Category: Emergency Medicine Source Type: research

Pneumonia Update for Emergency Clinicians
AbstractPurpose of ReviewMany new concepts in diagnosis, management, and risk stratification of patients with pneumonia have been described recently. The COVID pandemic made importance of viruses as dangerous pathogens of pneumonia quite clear while several non-invasive measures for patients with respiratory failure gained a more wide-spread usage.Recent FindingsStudies continue to examine feasibility of bedside ultrasound as a tool in accurate diagnosis of pneumonia in the emergency department, and several new antibiotics have been approved for treatment while others are in late-stage clinical trials. Additionally, the In...
Source: Current Emergency and Hospital Medicine Reports - July 20, 2022 Category: Emergency Medicine Source Type: research

OCS - Sparing Effect of Dupilumab for Severe Asthma Maintained
Oral corticosteroid dosage reduction sustained in open - label extension study of dupilumab
Source: Pulmonary Medicine News - Doctors Lounge - July 22, 2022 Category: Respiratory Medicine Tags: Family Medicine, Internal Medicine, Allergy, Pharmacy, Pulmonology, Journal, Source Type: news

Comparison of the characteristics, morbidity and mortality of COVID-19 between first and second/third wave in a hospital setting in Lombardy: a retrospective cohort study
In conclusion, our data suggest that earlier diagnosis, timely hospital admission and rational use of the therapeutic options reduced the systemic inflammatory response and were associated to a better outcome during the 2nd/3rd wave.
Source: Internal and Emergency Medicine - July 9, 2022 Category: Emergency Medicine Source Type: research