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Precision Medicine Exits the Hype Cycle and Enters into Productive Clinical Use
The notion of precision medicine broadly refers to the administration of a patient-specific treatment based on unique features of an individual or their disease that are identified in the laboratory. This concept is not new to medicine and has existed for many years to allow for the administration of compatible blood products and antibiotics selected based on antibiotic resistance testing. The modern incarnation of precision medicine leverages our ability to determine the molecular cause of genetic disorders and apply rational therapies based on specific disease-causing genetic variants.
Source: Clinics in Laboratory Medicine - May 19, 2020 Category: Laboratory Medicine Authors: Ryan J. Schmidt Tags: Preface Source Type: research

Transfusion Medicine Informatics
Clinical informatics has been described as the “relentless pursuit of assisting people” by using data and information technology to improve health care. A core principle is that a person supported by information technology is superior to either a person or machine alone. Striving toward this harmonization, the transfusion medicine field has had a significant number of accomplishments. Clinical informatics interventions have helped achieve better quality, efficiency, and safety in nearly all aspects of transfusion medicine. This review summarizes these accomplishments and provides a preview of novel ideas that could tra...
Source: Clinics in Laboratory Medicine - September 30, 2021 Category: Laboratory Medicine Authors: Thomas Schneider, Ronald Jackups Jr Source Type: research

UW Medicine Researchers Identify Blood Cell Genetic Mutations That Can Disrupt Liquid Biopsy Results
The discovery is yet another factor that must be considered when developing a liquid biopsy test clinical laboratories can use to detect cancer How often do disruptive elements present in Liquid biopsies result in misdiagnoses and unhelpful drug therapies for cancer? Researchers at the University of Washington School of Medicine (UW Medicine) in Seattle wanted […] The post UW Medicine Researchers Identify Blood Cell Genetic Mutations That Can Disrupt Liquid Biopsy Results appeared first on Dark Daily.
Source: Dark Daily - October 18, 2021 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Digital Pathology Laboratory Instruments & Laboratory Equipment Laboratory Pathology Laboratory Resources Laboratory Testing Molecular Diagnostics, Genetic Testing, Whole Gene Sequencing Precision Medicine ACS American Cancer Society ana Source Type: news

Updates in Blood Banking and Transfusion Medicine
The seeming duality of transfusion medicine as both a remarkably consistent and a notably dynamic clinical field is fascinating. Over a century ago, Karl Landsteiner discovered the ABO blood group by mixing red blood cells and sera from different individuals and observing agglutination, and this method, albeit with refinements, to characterize both red blood cells and antibodies against them remains a mainstay in blood bank testing today. Other aspects of blood banking and transfusion medicine, such as the use of pathogen reduction technology to mitigate risk of transfusion-transmitted infections in platelet products, unde...
Source: Clinics in Laboratory Medicine - October 22, 2021 Category: Laboratory Medicine Authors: Suzanne R. Thibodeaux Tags: Preface Source Type: research

Promotion to Top-Tier Journal and Development Strategy of the < em > Annals of Laboratory Medicine < /em > for Strengthening its Leadership in the Medical Laboratory Technology Category: A Bibliometric Study
CONCLUSIONS: The journal's promotion to an international top-tier journal has been successful. "Principles of transparency and best practice in scholarly publishing" and a preprint policy are yet to be added.PMID:34907102 | DOI:10.3343/alm.2022.42.3.321
Source: Annals of Laboratory Medicine - December 15, 2021 Category: Laboratory Medicine Authors: Sun Huh Source Type: research