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Highlights from this issue
Welcome to our first issue of 2014. UK readers will have followed with interest the recent publication of the 3rd National Survey of Sexual Attitudes and Lifestyles (Natsal—see natsal.ac.uk), which coincided with World AIDS day 2013. Population surveys however have their limitations—particularly in their ability to describe in useful detail minority sexual practices. These need to be explored through customised surveys using targeted recruitment, or through data collection systems of sufficiently large scale to capture useful numbers of these groups. Two populations in which Natsal has limited power are men who...
Source: Sexually Transmitted Infections - January 15, 2014 Category: Sexual Medicine Authors: Cassell, J. A. Tags: Liver disease, Epidemiologic studies, Drugs: infectious diseases, Hepatitis and other GI infections, HIV/AIDS, Vaccination / immunisation, Reproductive medicine, Adolescent health, Child health, Condoms, Hepatitis (sexual health), HIV / AIDS, Gonorrhoea, Source Type: research

Ending AIDS — Is an HIV Vaccine Necessary?
New England Journal of Medicine, Volume 370, Issue 6, Page 495-498, February 2014.
Source: New England Journal of Medicine - February 5, 2014 Category: Internal Medicine Tags: article Source Type: research

Use of Sargassum fusiforme Extract and its Bioactive Molecules to inhibit HIV Infection: Bridging Two Paradigms between Eastern and Western Medicine
Publication date: November 2014 Source:Chinese Herbal Medicines, Volume 6, Issue 4 Author(s): Hui-jun Guo , Yan-ze Liu , Elena E. Paskaleva , Manoj Arra , Jeffrey S. Kennedy , Alexander Shekhtman , Mario Canki AIDS is a global pandemic that has seen the development of novel and effective treatments to improve the quality of life of those infected and reduction in the spread of the disease. While great advancements have been made in HIV/AIDS therapeutics, there is still no cure or viable vaccine in development. The high rate of HIV-1 mutation contributing to virus immune escape, combined with increase in sexual transmissi...
Source: Chinese Herbal Medicines - November 27, 2014 Category: Complementary Medicine Source Type: research

New Vaccines for the World's Poorest People.
Abstract The 2000 Millennium Development Goals helped stimulate the development of life-saving childhood vaccines for pneumococcal and rotavirus infections while greatly expanding coverage of existing vaccines. However, there remains an urgent need to develop new vaccines for HIV/AIDS, malaria, and tuberculosis, as well as for respiratory syncytial virus and those chronic and debilitating (mostly parasitic) infections known as neglected tropical diseases (NTDs). The NTDs represent the most common diseases of people living in extreme poverty and are the subject of this review. The development of NTD vaccines, inclu...
Source: Annual Review of Medicine - September 3, 2015 Category: Journals (General) Authors: Hotez PJ, Bottazzi ME, Strych U Tags: Annu Rev Med Source Type: research

The mechanism of an AIDS vaccine candidate filmed in vivo
(Institut Pasteur) Using innovative technology, scientists from the Institut Pasteur and Inserm have filmed in vivo the process by which an AIDS vaccine candidate, developed by the French Vaccine Research Institute and the ANRS, triggers the immune response. This previously unseen footage clearly shows how the vaccine recruits the immune cells needed to destroy infected cells. These results, published in the journal Nature Medicine on Dec. 21, 2015, shed new light on the mode of action and potential of this vaccine.
Source: EurekAlert! - Medicine and Health - December 22, 2015 Category: Global & Universal Source Type: news

Researchers Find Alternative Pathways to HIV Antibodies
Contact: Sarah Avery Phone: 919-660-1306 Email: sarah.avery@duke.edu https://www.dukehealth.org FOR IMMEDIATE RELEASE on Tuesday, May 3, 2016 DURHAM, N.C. – The immune system appears to hamper an investigational vaccine from inducing antibodies that protect against HIV infection, but there may be ways to overcome this impediment, according to research led by the Duke Human Vaccine Institute. Using mouse and monkey models, the researchers showed they could could identify the roadblocks to inducing the broadly neutralizing antibodies that are considered imperative for successful protection against infection.  They then fo...
Source: DukeHealth.org: Duke Health Features - May 3, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Tracking How HIV Disrupts Immune System Informs Vaccine Development
Contact: Samiha Khanna Phone: 919-419-5069 Email: samiha.khanna@duke.edu https://www.dukehealth.org EMBARGOED FOR RELEASE until 2 p.m. (ET) on Friday, July 29, 2016 DURHAM, N.C. -- One of the main mysteries confounding development of an HIV vaccine is why some people infected with the virus make the desired antibodies after several years, but a vaccine can ’t seem to induce the same response. A research team led by scientists at the Duke Human Vaccine Institute has been unraveling that mystery, detailing new insights in a study published July 29 in the journal Science Immunology. Studying 100 HIV-infected people ...
Source: DukeHealth.org: Duke Health Features - July 29, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

Feline-assisted therapy: Integrating contact with cats into treatment plans
Conclusions Feline-assisted therapy can be used in a variety of settings, and it is gaining increased popularity. Cat-assisted therapy is particularly recommended for patients who are unable to interact with large animals such as horses or are afraid of dogs.
Source: Polish Annals of Medicine - March 17, 2017 Category: Journals (General) Source Type: research

The global tuberculosis epidemic and progress in care, prevention, and research: an overview in year 3 of the End TB era
Publication date: April 2018 Source:The Lancet Respiratory Medicine, Volume 6, Issue 4 Author(s): Katherine Floyd, Philippe Glaziou, Alimuddin Zumla, Mario Raviglione Tuberculosis is the number one cause of death from infectious disease globally and drug-resistant forms of the disease are a major risk to global health security. On the occasion of World Tuberculosis Day (March 24, 2018), we provide an up-to-date review of the status of the tuberculosis epidemic, recommended diagnostics, drug treatments and vaccines, progress in delivery of care and prevention, progress in research and development, and actions needed to acc...
Source: The Lancet Respiratory Medicine - March 24, 2018 Category: Respiratory Medicine Source Type: research

Demystifying Medicine 2019
Source: National Institutes of Health (NIH). Published: 1/8/2019. This one-hour, 48-minute presentation discusses the history of pandemics, their challenges, and the next influenza pandemic. Topics include the role of viral, host, and secondary bacterial factors in influenza pathogenesis; contemporary Avian influenza, and why an HIV vaccine Is essential for ending the HIV/AIDS pandemic. (Video or Multimedia)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - January 10, 2019 Category: International Medicine & Public Health Source Type: news

Demystifying Medicine 2019: The Next Influenza Pandemic and Ending the HIV/AIDS Pandemic: Follow the Science
Source: National Institutes of Health (NIH). Published: 1/8/2019. This one-hour, 48-minute presentation discusses the history of pandemics, their challenges, and the next influenza pandemic. Topics include the role of viral, host, and secondary bacterial factors in influenza pathogenesis; contemporary Avian influenza, and why an HIV vaccine Is essential for ending the HIV/AIDS pandemic. (Video or Multimedia)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - January 10, 2019 Category: International Medicine & Public Health Source Type: news

Why Don ' t We Have a Vaccine for SARS or MERS? Why Don ' t We Have a Vaccine for SARS or MERS?
We don ' t have vaccines for SARS, MERS, or HIV. Does that spell doom for efforts to develop a vaccine for SARS-CoV-2?Medscape Internal Medicine
Source: Medscape Hiv-Aids Headlines - May 28, 2020 Category: Infectious Diseases Tags: Internal Medicine Commentary Source Type: news

Adult Vaccines 2022: Who Needs What, and When? Adult Vaccines 2022: Who Needs What, and When?
Dr Sandra Fryhofer hits the highlights of the 2022 adult immunization schedule, just released by ACIP.Medscape Internal Medicine
Source: Medscape Hiv-Aids Headlines - February 17, 2022 Category: Infectious Diseases Tags: Internal Medicine Commentary Source Type: news

Why I Recommend Hepatitis B Vaccination to All My Patients Why I Recommend Hepatitis B Vaccination to All My Patients
New age-based hepatitis B vaccine recommendations and available vaccine products are reviewed by Dr Sandra Fryhofer.Medscape Internal Medicine
Source: Medscape Hiv-Aids Headlines - May 3, 2022 Category: Infectious Diseases Tags: Internal Medicine Commentary Source Type: news

The Virus Hunters Trying to Prevent the Next Pandemic
Nobody saw SARS-CoV-2 coming. In the early days of the pandemic, researchers were scrambling to collect samples from people who had mysteriously developed fevers, coughs, and breathing problems. Pretty soon, they realized that the disease-causing culprit was a new virus humans hadn’t seen before. And the world, lacking a coordinated global response, was unprepared. Some countries acted quickly to develop tests for the novel coronavirus, while others with fewer resources were left behind. With a virus oblivious to national borders, and with travel between countries and continents more common than it had been in previo...
Source: TIME: Health - August 1, 2022 Category: Consumer Health News Authors: Alice Park and Video by Andrew D. Johnson Tags: Uncategorized Disease Frontiers of Medicine 2022 healthscienceclimate Source Type: news