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Specialty: Laboratory Medicine
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Total 31064 results found since Jan 2013.
Personalized medicine and ethics.
Abstract
An entire series could be dedicated to the topic of ethics in personalized medicine. Due to the advancements in NGS and genetic testing, personalized medicine is no longer something that will occur in the future, the reality is upon us now. Sequencing an individual's genome can have a substantial impact on the patient's treatment and overall quality of life. However, this can open "Pandora's box" especially if an individual does not want to know the information obtained. In addition, will insurance companies require genetic testing in order to pay for a targeted treatment? If the patient refuses to have t...
Source: Clinical Laboratory Science : Journal of the American Society for Medical Technology - September 18, 2014 Category: Laboratory Medicine Authors: Josko D Tags: Clin Lab Sci Source Type: research
Evidence-Based Pathology: Systematic Literature Reviews as the Basis for Guidelines and Best Practices.
Conclusions .- Evidence-based pathology provides methodology to evaluate the quality of information published in pathology journals and apply it to the diagnosis of tissue samples and other tests from individual patients. Information is gathered through the use of systematic reviews, using a method that is less biased and more comprehensive than ad hoc literature searches. Published data are classified into evidence levels to provide readers with a quick impression about the quality and probable clinical validity of available information. Best available evidence is combined with personal experience for the formulation of e...
Source: Archives of Pathology and Laboratory Medicine - October 30, 2014 Category: Laboratory Medicine Authors: Marchevsky AM, Wick MR Tags: Arch Pathol Lab Med Source Type: research
Underutilization of Meta-analysis in Diagnostic Pathology.
Conclusions .- We found underutilization of meta-analyses in DP, despite their high ACRs and recently increased utilization. More DP meta-analyses are needed.
PMID: 26414474 [PubMed - in process]
Source: Archives of Pathology and Laboratory Medicine - September 30, 2015 Category: Laboratory Medicine Authors: Kinzler M, Zhang L Tags: Arch Pathol Lab Med Source Type: research
Integration of molecular pathology, epidemiology and social science for global precision medicine.
Authors: Nishi A, Milner DA, Giovannucci EL, Nishihara R, Tan AS, Kawachi I, Ogino S
Abstract
The precision medicine concept and the unique disease principle imply that each patient has unique pathogenic processes resulting from heterogeneous cellular genetic and epigenetic alterations and interactions between cells (including immune cells) and exposures, including dietary, environmental, microbial and lifestyle factors. As a core method field in population health science and medicine, epidemiology is a growing scientific discipline that can analyze disease risk factors and develop statistical methodologies to maxi...
Source: Expert Review of Molecular Diagnostics - December 23, 2015 Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research
Diagnostic Error in Medicine: Implications for Clinical Laboratory Scientists.
This article discusses the extent and types of diagnostic error in medicine, the challenges of studying diagnostic error, and strategies to address these errors. The role of the clinical laboratory in regard to diagnostic errors in medicine is also highlighted.
PMID: 29263037 [PubMed - in process]
Source: Annals of Clinical and Laboratory Science - November 1, 2017 Category: Laboratory Medicine Authors: Berner ES Tags: Ann Clin Lab Sci Source Type: research
Key questions about the future of laboratory medicine in the next decade of the 21st century
Publication date: Available online 28 May 2019Source: Clinica Chimica ActaAuthor(s): Ronda Greaves, Sergio Bernardini, Maurizio Ferrari, Paolo Fortina, Bernard Gouget, Damien Gruson, Tim Lang, Tze Ping Loh, Howard Morris, Jason Y. Park, Markus Roessler, Peng Yin, Larry J. KrickaAbstractThis review advances the discussion about the future of Laboratory Medicine in the 2020s. In five major topic areas: 1. the “big picture” of healthcare; 2. pre-analytical factors; 3. Analytical factors; 4. post-analytical factors; and 5. relationships, which explores a next decade perspective on Laboratory Medicine and the likely impact ...
Source: Clinica Chimica Acta - May 28, 2019 Category: Laboratory Medicine Source Type: research
Key questions about the future of laboratory medicine in the next decade of the 21st century: A report from the IFCC-Emerging Technologies Division
Publication date: August 2019Source: Clinica Chimica Acta, Volume 495Author(s): Ronda F. Greaves, Sergio Bernardini, Maurizio Ferrari, Paolo Fortina, Bernard Gouget, Damien Gruson, Tim Lang, Tze Ping Loh, Howard A. Morris, Jason Y. Park, Markus Roessler, Peng Yin, Larry J. KrickaAbstractThis review advances the discussion about the future of laboratory medicine in the 2020s. In five major topic areas: 1. the “big picture” of healthcare; 2. pre-analytical factors; 3. Analytical factors; 4. post-analytical factors; and 5. relationships, which explores a next decade perspective on laboratory medicine and the likely impact...
Source: Clinica Chimica Acta - June 14, 2019 Category: Laboratory Medicine Source Type: research
Pathology Engagement in Global Health
CONCLUSIONS.—: Our data demonstrate that laboratory medicine professionals are highly interested in global pathology efforts, but factors such as lack of time, lack of funding, and lack of knowledge of potential volunteer opportunities are barriers to participation. A significant number of respondents were willing and able to participate, indicating that pathology and laboratory medicine professionals may be an untapped resource for global health volunteers.PMID:35196380 | DOI:10.5858/arpa.2021-0239-OA
Source: Archives of Pathology and Laboratory Medicine - February 23, 2022 Category: Laboratory Medicine Authors: Dana Razzano Jerad M Gardner Allison Hall Xiaoyin Sara Jiang Source Type: research
Burnout and Disengagement in Pathology
CONCLUSIONS.—: Data provided from this cohort may help departments create successful strategies to reduce disengagement and burnout in the laboratory, especially during periods of increased stress as experienced during the COVID-19 pandemic. Further, these data may serve as a baseline comparison for future studies.PMID:36191345 | DOI:10.5858/arpa.2022-0073-OA
Source: Archives of Pathology and Laboratory Medicine - October 3, 2022 Category: Laboratory Medicine Authors: Stephen M Smith Daniel Liauw David Dupee Andrea L Barbieri Kristine Olson Vinita Parkash Source Type: research
