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Expanding Research Capacity in Sub-Saharan Africa Through Informatics, Bioinformatics, and Data Science Training Programs in Mali
Conclusion Bioinformatics and data science training programs in developing countries necessitate incremental and collaborative strategies for their feasible and sustainable development. The progress described here covered decades of collaborative efforts centered on training and research on computationally intensive topics. These efforts laid the groundwork and platforms conducive for hosting a bioinformatics and data science training program in Mali. Training programs are perhaps best facilitated through Africa’s university systems as they are perhaps best positioned to maintain core resources during lapses in sho...
Source: Frontiers in Genetics - April 11, 2019 Category: Genetics & Stem Cells Source Type: research

Exciting Antibody Discovery Sparks New Hope For Future HIV Vaccine
Scientists have discovered an antibody that can powerfully neutralize many variants of the most common strain of HIV, opening up a door for researchers to explore treatment and prevention options for the potentially fatal virus.  Antibodies ― proteins created by our immune system that are in charge of spotting and neutralizing potentially harmful substances in our body ― are promising avenues for potential vaccines and treatments against the virus.  The new antibody, named N6, was isolated from the blood of a person with HIV. It managed to neutralize 98 percent of the HIV variants that researchers tested it o...
Source: Healthy Living - The Huffington Post - November 17, 2016 Category: Consumer Health News Source Type: news

UCLA scientists receive $7.7 million grant to study HIV recurrence
The virus that causes AIDS is known to hide in certain rare cells. When people with HIV stop taking their medications, the virus can re-emerge and multiply, or “rebound,” from those hiding places. To better combat HIV, scientists have been working to understand how and why the virus re-emerges.“It’s the resurrection of virus that you couldn’t see in the body before,” said Jerome Zack, professor of medicine and chair of the UCLA department of microbiology, immunology and molecular genetics at the David Geffen School of Medicine at UCLA. Zack, who is director of the  UCLA Center for AIDS Research, and colleague...
Source: UCLA Newsroom: Health Sciences - February 16, 2018 Category: Universities & Medical Training Source Type: news

Vaccines, Antibodies and Drug Libraries. The Possible COVID-19 Treatments Researchers Are Excited About
In early April, about four months after a new, highly infectious coronavirus was first identified in China, an international group of scientists reported encouraging results from a study of an experimental drug for treating the viral disease known as COVID-19. It was a small study, reported in the New England Journal of Medicine, but showed that remdesivir, an unapproved drug that was originally developed to fight Ebola, helped 68% of patients with severe breathing problems due to COVID-19 to improve; 60% of those who relied on a ventilator to breathe and took the drug were able to wean themselves off the machines after 18...
Source: TIME: Health - April 14, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

NIDCR's Spring 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Spring 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NICDR News Science Advances   Grantee News   NIDCR News NIDCR & NIH Stand Against Structural Racism NIDCR Director Rena D’Souza, DDS, MS, PhD, said in a statement that there is no place for structural racism in biomedical research, echoing remarks from NIH Director Francis Collins, MD, PhD, in his announcement of a new NIH initiative—called UNIT...
Source: NIDCR Science News - April 7, 2021 Category: Dentistry Source Type: news

What are Some Health Risks that LGBTQ Youth are at Risk For?
Discussion LGBTQ (lesbian, gay, bisexual, transgender and questioning people) terminology describes sexual orientation, not sexual behavior and is a common term used. Individuals may reject this term and prefer other terminology such as a man having sex with other men (MSM) or a woman having sex with other women (WSW). Over time terminology may change also, such as the word queer that has had a negative connotation, but in contemporary usage is also used as a unifying term for anyone who is a sexual minority. Some sexual definitions include: Sexual orientation is the sexual desire for a particular gender, or an intensive...
Source: PediatricEducation.org - September 9, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Changing patterns and progress in venereology
Abstract: This paper provides a summary of the philosophy of modern concepts on venereology, the control and treatment of sexually transmitted infections (STIs). There is a basis in professional education, based on evidence based medicine. From that follows a much wider dissemination to the public on the personal and community aspects of STIs. The World Wide Web has had profound effects on rapid developments in this field. STIs are more frequent in some groups in the general population. Epidemiological trends in STIs from the United States and Europe are described. Interventions to prevent the spread of STIs not only by ch...
Source: Clinics in Dermatology - February 21, 2014 Category: Dermatology Authors: Michael Waugh Source Type: research

Ebola 3.0
By Susan J. Blumenthal, M.D., and Jennifer Sherwood, M.P.H. The doctors, nurses and other health care workers who responded to the Ebola epidemic in West Africa were recently named Time magazine's "Person of the Year." The courageous individuals who dedicate their careers and risk their lives to help in times of global public health emergencies such as Ebola deserve this recognition. A new report shows that health care workers have more than 100 times the risk of being infected with Ebola in Sierra Leone as the general public there. The World Health Organization (WHO) estimates that 622 health care workers have acquired t...
Source: Healthy Living - The Huffington Post - December 18, 2014 Category: Consumer Health News Source Type: news

4 New Scientific Breakthroughs To Celebrate This World AIDS Day
There is still no cure or vaccine for HIV/AIDS, which affects approximately 37 million people around the world. But there is reason to hope that the global response to this pandemic is improving.  Fewer people died of HIV in 2015 than at any point in almost 20 years, while new HIV infections are at the lowest point since 1991, the World Health Organization noted in its 2016 progress report. That may be, in part, because at least two million new people began taking antiretroviral therapy in 2015, the largest annual increase ever in the history of the disease.  For World AIDS Day, we asked resea...
Source: Science - The Huffington Post - December 1, 2016 Category: Science Source Type: news

2016 Was A Banner Year For HIV/AIDS Research
There is still no cure or vaccine for HIV/AIDS, which affects approximately 37 million people around the world. But there is reason to hope that the global response to this pandemic is improving.  Fewer people died of HIV in 2015 than at any point in almost 20 years, while new HIV infections are at the lowest point since 1991, the World Health Organization noted in its 2016 progress report. That may be, in part, because at least two million new people began taking antiretroviral therapy in 2015, the largest annual increase ever in the history of the disease.  For World AIDS Day, we asked resea...
Source: Science - The Huffington Post - December 1, 2016 Category: Science Source Type: news

Women’s History Month: Defending A Woman’s Right To Live HIV/AIDS-Free In America
By Susan J. Blumenthal, M.D., M.P.A. This piece was adapted from an article first published on The Advocate for National Women and Girls HIV/AIDS Awareness Day on March 10, 2017. The landmark Women’s March in January brought millions of people in America and around the world together in support of women’s rights, equality, expanding access to healthcare, and protecting the environment. As I witnessed legions of women, men, and children take to the street to make an indelible mark during Women’s History Month, I was reminded of the remarkable progress we have made over the past two decades in advancing wom...
Source: Healthy Living - The Huffington Post - March 22, 2017 Category: Consumer Health News Source Type: news

Poly-ICLC, a TLR3 Agonist, Induces Transient Innate Immune Responses in Patients With Treated HIV-Infection: A Randomized Double-Blinded Placebo Controlled Trial
Conclusions: These finding suggest that Poly-ICLC could be safely used for inducing transient innate immune responses in treated HIV+ subjects indicating promise as an adjuvant for HIV therapeutic vaccines. Trial Registration: www.ClinicalTrials.gov, identifier: NCT02071095. Introduction Innate immune dysregulation during HIV infection hinders the formation of anti-HIV adaptive immunity (1–6) resulting in rampant viral dissemination and progression to AIDS. Adherence to combination anti-retroviral therapy (cART) regimens controls viremia, restores CD4+T cell counts and reverses immune dysfunction to ...
Source: Frontiers in Immunology - April 8, 2019 Category: Allergy & Immunology Source Type: research

In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection
Conclusion: The Mtb infection status had a significant impact on mycobacterial growth inhibition in PBMC from healthy adults in South Korea, a country with an intermediate burden of tuberculosis, with healthy controls showing the greatest mycobacterial growth inhibition. Introduction Pulmonary tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis (Mtb), which is a significant burden for the world, reaching 9.6 million new TB cases and 1.5 million deaths per year (1). Also, just under a quarter of the global population is latently infected with Mtb, and 5–10% of them will d...
Source: Frontiers in Immunology - April 25, 2019 Category: Allergy & Immunology Source Type: research