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Practical SPECT/CT in Nuclear Medicine
Source: Springer Medicine titles - April 5, 2013 Category: Databases & Libraries Tags: Nuclear Medicine Source Type: news

Nuclear Medicine Procedures in the Diagnosis of NET: A Historical Perspective
Novel diagnostic tools and therapies have emerged as a result of the continuous endeavors relating to neuroendocrine tumors (NETs). Nuclear medicine plays a pivotal role in the imaging and treatment of NETs. Somatostatin receptor analogues and metaiodobenzylguanidine remain front-line single-photon emission computed tomography (SPECT) radiotracers in the imaging of NET; their utility has been augmented by the increasing availability of SPECT/CT. Positron emission tomography has been growing rapidly in the imaging of NETs, paralleled by great efforts toward the development of new tracers. Hybrid imaging will play an importa...
Source: PET Clinics - October 7, 2013 Category: Radiology Authors: Anna Margherita Maffione, Sellam Karunanithi, Rakesh Kumar, Domenico Rubello, Abass Alavi Tags: Section I: Nuclear Medicine in the Diagnosis and Treatment of Neuroendocrine Neoplasms Source Type: research

PET and SPECT Imaging in Veterinary Medicine
This article provides an overview of the potential applications of PET and SPECT. The use of commercially available and investigational PET radiopharmaceuticals in the management of veterinary disease has been discussed. To date, most of the work in this field has utilized the commercially available PET tracer, 18F-fluorodeoxyglucose for oncologic imaging. Normal biodistribution studies in several companion animal species (cats, dogs, and birds) have been published to assist in lesion detection and interpretation for veterinary radiologists and clinicians. Studies evaluating other 18F-labeled tracers for research applicati...
Source: Seminars in Nuclear Medicine - December 6, 2013 Category: Radiology Authors: Amy K. LeBlanc, Kathelijne Peremans Source Type: research

Letter from the Guest Editor: Update in Cardiovascular Nuclear Medicine
There have been many advances in the field of cardiovascular nuclear imaging since the most recent review of the topic in Seminars in Nuclear Medicine almost 10 years ago in January 2005. The assortment of articles by leaders in the field in this part 1 issue and in the part 2 issue coming in September provides in-depth descriptions of SPECT, PET, and hybrid imaging technological advancements related to acquiring and processing cardiac images using current standard and potential new radiotracers, better understood and expanded clinical applications in patients with a variety of heart conditions that include not only corona...
Source: Seminars in Nuclear Medicine - June 19, 2014 Category: Radiology Authors: Mark I. Travin Source Type: research

Design study of a Laue lens for nuclear medicine
A Laue lens is an ensemble of crystals capable of focusing, through diffraction in transmission geometry, a fraction of the photons emitted by an X- or γ-ray source onto a small area of a detector. The present study facilitates a thorough understanding of the effect of each system parameter on the efficiency, the resolution and the field of view of the lens. In this way, the structure and the size of the crystals can be set to achieve a compact lens capable of providing a high-resolution image of the radioactivity distribution lying inside a restricted region of a patient's body. As an application, a Laue lens optimized a...
Source: Journal of Applied Crystallography - January 10, 2015 Category: Physics Authors: Paternò, G.Bellucci, V.Camattari, R.Guidi, V. Tags: Laue lenses nuclear medicine X-ray diffraction curved crystals research papers Source Type: research

Patient dosimetry in nuclear medicine
In diagnostic nuclear medicine, the biokinetics of the radiopharmaceutical (actually of the radionuclide) is determined for a number of representative patients. At therapy, it is essential to determine the patient's individual biokinetics of the radiopharmaceutical in order to calculate the absorbed doses to critical normal organs/tissues and to the target volume(s) with high accuracy. For the diagnostic situations, there is still a lack of quantitative determinations of the organ/tissue contents of radiopharmaceuticals and their variation with time. Planar gamma camera imaging using the conjugate view technique combined w...
Source: Radiation Protection Dosimetry - July 13, 2015 Category: Radiology Authors: Mattsson, S. Tags: Nuclear medicine Source Type: research

Current Status of Nuclear Medicine Practice in Latin America and the Caribbean
The practice of nuclear medicine (NM) in the Latin American and Caribbean region has experienced important growth in the last decade. However, there is great heterogeneity among countries regarding the availability of technology and human resources. According to data collected through June 2014 by the International Atomic Energy Agency (IAEA), the total number of cameras in the region is 1,231, with an average of 2.16 per million inhabitants. Over 90% of the equipment is SPECT cameras; 7.6% of which have hybrid technology. There are 161 operating PET or PET/CT cameras in 12 member states, representing a rate of 0.3 per mil...
Source: Journal of Nuclear Medicine - October 1, 2015 Category: Nuclear Medicine Authors: Paez, D., Orellana, P., Gutierrez, C., Ramirez, R., Mut, F., Torres, L. Tags: Special Contributions Source Type: research

Normal values and standardization of parameters in nuclear cardiology: Japanese Society of Nuclear Medicine working group database
Abstract As a 2-year project of the Japanese Society of Nuclear Medicine working group activity, normal myocardial imaging databases were accumulated and summarized. Stress-rest with gated and non-gated image sets were accumulated for myocardial perfusion imaging and could be used for perfusion defect scoring and normal left ventricular (LV) function analysis. For single-photon emission computed tomography (SPECT) with multi-focal collimator design, databases of supine and prone positions and computed tomography (CT)-based attenuation correction were created. The CT-based correction provided similar perfusion patt...
Source: Annals of Nuclear Medicine - February 20, 2016 Category: Nuclear Medicine Source Type: research

Performance of cardiac cadmium-zinc-telluride gamma camera imaging in coronary artery disease: a review from the cardiovascular committee of the European Association of Nuclear Medicine (EANM)
AbstractThe trade-off between resolution and count sensitivity dominates the performance of standard gamma cameras and dictates the need for relatively high doses of radioactivity of the used radiopharmaceuticals in order to limit image acquisition duration. The introduction of cadmium-zinc-telluride (CZT)-based cameras may overcome some of the limitations against conventional gamma cameras. CZT cameras used for the evaluation of myocardial perfusion have been shown to have a higher count sensitivity compared to conventional single photon emission computed tomography (SPECT) techniques. CZT image quality is further improve...
Source: European Journal of Nuclear Medicine and Molecular Imaging - November 3, 2016 Category: Nuclear Medicine Source Type: research

Automatic cumulative sums contour detection of FBP-reconstructed multi-object nuclear medicine images
The problem of determining the contours of objects in nuclear medicine images has been studied extensively in the past, however most of the analysis has focused on a single object as opposed to multiple objects. The aim of this work is to develop an automated method for determining the contour of multiple objects in positron emission tomography (PET) and single photon emission computed tomography (SPECT) filtered backprojection (FBP) reconstructed images. These contours can be used for computing body edges for attenuation correction in PET and SPECT, as well as for eliminating streak artifacts outside the objects, which co...
Source: Computers in Biology and Medicine - April 14, 2017 Category: Bioinformatics Authors: Nicholas E. Protonotarios, George M. Spyrou, George A. Kastis Source Type: research

Evaluating imaging protocols for quantitative nuclear-medicine imaging using patient data
Conclusion: A NO-NGS technique developed to evaluate imaging protocols (IPs) for quantitative imaging when different sets of patients are scanned using different IPs was shown to estimate figures of merit to quantify the accuracy of the different IPs for quantitative SPECT in the absence of any gold standard.
Source: Journal of Nuclear Medicine - May 24, 2017 Category: Nuclear Medicine Authors: Jha, A., Sgouros, G., Frey, E. Tags: Dosimetry and Image Analysis Source Type: research

Phantom Evaluation of Bone Imaging in a Clinical Nuclear Medicine Environment
Conclusion: This evaluation illustrated differences in image quality for whole body and SPECT bone imaging that were not revealed by routine annual physicist testing. This illustrates the importance of protocol specific phantom image quality evaluation in determining the clinical utilization of each system and in adjusting acquisition and processing parameters to optimize the performance of each system. Research Support: N/A.
Source: Journal of Nuclear Medicine - May 24, 2017 Category: Nuclear Medicine Authors: Dharmadhikari, S., Brandon, D., Nye, J., Aarsvold, J., Galt, J. Tags: Instrumentation Posters Source Type: research

Development of a deep learning-based interpretation model for brain perfusion SPECT leveraging unstructured reading reports
Conclusions: We suggest a pipeline for developing a deep learning-based image interpretation system for brain perfusion SPECT using image data combined with unstructured text reports. Considering that labels of medical images in the clinical routine are usually unstructured and complicated, an additional deep learning model to synthesize structured labels may facilitate the development of efficient image interpretation models based on CNN. According to our results, the deep learning-based image interpretation system of brain perfusion SPECT images is expected to be useful to support the human visual interpretation.
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Ryoo, H. G., Choi, H., Wong, T. H., Kang, S. K., Lee, J. S., Lee, D. S. Tags: Machine Learning in Nuclear Medicine Imaging I: Image Processing and Clinical Tasks Source Type: research

3D Post Procedural Masking Technique to Improve Visibility of Small Lymph Node in Nuclear Medicine SPECT/CT Exams
Conclusions: Digital masking has improved contrast resolution and sentinel lymph node detection significantly in H/N lymphoscintigraphy. Future studies will compare SPECT/CT with digital masking to PET/CT.
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Tran, D., Gingold, E., Parekh, M., Rickley, C., Intenzo, C., Kim, S. Tags: Tech Papers IV: Instrumentation & amp; Data Analysis Source Type: research

Kihito, a Traditional Japanese Kampo Medicine, Improves Cognitive Function in Alzheimer's Disease Patients.
Conclusion: Kihito improves cognitive function in AD patients. PMID: 31217803 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - June 21, 2019 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research