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Specialty: Laboratory Medicine

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Total 31064 results found since Jan 2013.

Laboratory medicine as the science that underpins medicine: the “high-sensitivity” troponin paradigm
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
Source: Clinical Chemistry and Laboratory Medicine - November 18, 2014 Category: Laboratory Medicine Source Type: research

The pathology residency program of the johns hopkins university school of medicine: a model of its kind.
Conclusions .- While maintaining its original core values, the Johns Hopkins Pathology Residency Program has trained physicians to be outstanding researchers, diagnosticians, and leaders in pathology. PMID: 25724037 [PubMed - in process]
Source: Archives of Pathology and Laboratory Medicine - March 1, 2015 Category: Laboratory Medicine Authors: Caturegli P, McCarthy EF, Jackson JB, Hruban RH Tags: Arch Pathol Lab Med Source Type: research

Evidence-based medicine, Lab medicine practice guidelines, decision making
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Volume: 53Issue: s1Pages: s560-s579
Source: Clinical Chemistry and Laboratory Medicine - May 20, 2015 Category: Laboratory Medicine Source Type: research

Laboratory medicine does matter in science (and medicine)… yet many seem to ignore it
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
Source: Clinical Chemistry and Laboratory Medicine - August 21, 2015 Category: Laboratory Medicine Source Type: research

Laboratory medicine: let’s say it is the mirror of science (and medicine)
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
Source: Clinical Chemistry and Laboratory Medicine - September 21, 2015 Category: Laboratory Medicine Source Type: research

PD-L1 and Lung Cancer: The Era of Precision-ish Medicine?
Abstract The success of immune checkpoint inhibitor therapy in lung cancer, both in squamous and nonsquamous non-small cell carcinoma, has led to US Food and Drug Administration approval for 2 medications that have as part of their prescribing information an associated immunohistochemistry-based companion or complementary diagnostic test for programmed death ligand 1 (PD-L1). The intense interest in drug development in this area has resulted in additional agents with associated diagnostics looming on the horizon in 2016. In the era of precision medicine, the paradigm of paired molecular target and molecular test, ...
Source: Archives of Pathology and Laboratory Medicine - January 12, 2016 Category: Laboratory Medicine Authors: Borczuk AC, Allen TC Tags: Arch Pathol Lab Med Source Type: research

The Archives of Pathology & Laboratory Medicine: The Most Widely Read Pathology Journal Today.
The Archives of Pathology & Laboratory Medicine: The Most Widely Read Pathology Journal Today. Arch Pathol Lab Med. 2016 May 3; Authors: Allen TC Abstract The Archives of Pathology & Laboratory Medicine was first published in 1926 as a subspecialty journal of the American Medical Association. It became the official journal of the College of American Pathologists in 1995. Under the dynamic leadership of its most recent editor-in-chief, Philip T. Cagle, MD, and his vibrant editorial board, the Archives has nearly doubled its impact factor and become the most widely read general pathology journal...
Source: Archives of Pathology and Laboratory Medicine - May 2, 2016 Category: Laboratory Medicine Authors: Allen TC Tags: Arch Pathol Lab Med Source Type: research

Precision Medicine in Toxicology
Precision medicine applies primarily to pharmacokinetics in toxicology. Mastering hepatic metabolism through an understanding of the genetics behind Phase I, or oxidation/reduction and some Phase II, or conjugation, enhances the scientific and clinical application of common drug toxicology. This review includes basic hepatic metabolism, the common substrates, inducers and inhibitors of cytochrome P450 along with genetic variants behind the enzymes. Detailed metabolism of commonly measured opioids in clinical practice is provided. Finally, evidence based research and clinical correlations conclude that knowledge of inducers...
Source: Clinics in Laboratory Medicine - November 12, 2016 Category: Laboratory Medicine Authors: Daniel A. Schwarz, M.P. George, Martin H. Bluth Source Type: research

Integrated Pathology Informatics Enables High-Quality Personalized and Precision Medicine: Digital Pathology and Beyond.
CONCLUSION: - This approach builds the foundation for accurate big data collection and high-quality personalized and precision medicine. PMID: 28849944 [PubMed - as supplied by publisher]
Source: Archives of Pathology and Laboratory Medicine - August 29, 2017 Category: Laboratory Medicine Authors: Volynskaya Z, Chow H, Evans A, Wolff A, Lagmay-Traya C, Asa SL Tags: Arch Pathol Lab Med Source Type: research

The European Federation of Clinical Chemistry and Laboratory Medicine syllabus for postgraduate education and training for Specialists in Laboratory Medicine: version 5 – 2018
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM) Issue: Ahead of print
Source: Clinical Chemistry and Laboratory Medicine - June 5, 2018 Category: Laboratory Medicine Source Type: research

Clinical Chemistry and Laboratory Medicine continues to shine brightly in the constellation of laboratory medicine
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM) Issue: Ahead of print
Source: Clinical Chemistry and Laboratory Medicine - July 11, 2018 Category: Laboratory Medicine Source Type: research

Congress of Laboratory Medicine and Clinical Chemistry 7th Annual Meeting of the Austrian Society for Laboratory Medicine and Clinical Chemistry ( ÖGLMKC)
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM) Issue: Ahead of print
Source: Clinical Chemistry and Laboratory Medicine - October 16, 2018 Category: Laboratory Medicine Source Type: research

Reporting Quality of Diagnostic Accuracy Studies in Laboratory Medicine: Adherence to Standards for Reporting of Diagnostic Accuracy Studies (STARD) 2015.
CONCLUSIONS: Adherence to STARD 2015 is suboptimal among diagnostic accuracy studies published in ALM. Our study emphasizes the necessity of adherence to STARD to improve the reporting quality of future diagnostic accuracy studies to be published in ALM. PMID: 31858765 [PubMed - in process]
Source: Annals of Laboratory Medicine - December 22, 2019 Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research

Application of Next Generation Sequencing in Laboratory Medicine.
Authors: Zhong Y, Xu F, Wu J, Schubert J, Li MM Abstract The rapid development of next-generation sequencing (NGS) technology, including advances in sequencing chemistry, sequencing technologies, bioinformatics, and data interpretation, has facilitated its wide clinical application in precision medicine. This review describes current sequencing technologies, including short- and long-read sequencing technologies, and highlights the clinical application of NGS in inherited diseases, oncology, and infectious diseases. We review NGS approaches and clinical diagnosis for constitutional disorders; summarize the applicat...
Source: Annals of Laboratory Medicine - August 26, 2020 Category: Laboratory Medicine Tags: Ann Lab Med Source Type: research