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In this issue of Occupational Medicine
Evidence-based practice is a theme running through this issue ofOccupational Medicine. In ‘Occupational medicine: paradise lost’, Paul Nicholson [1] discusses the crisis which occupational medicine finds itself in. He suggests the need for a better focus on the internal and external issues and recommends a clear strategy to address these, underpinned by primary research to improve the knowledge and evidence base for practice. An important resource producing high-quality reviews of evidence in occupational health is Cochrane Work [2]. This resource can assist practitioners in identifying what we should implement from th...
Source: Occupational Medicine - October 11, 2017 Category: Respiratory Medicine Source Type: research

Personalised medicine in sleep respiratory disorders: focus on obstructive sleep apnoea diagnosis and treatment
In all fields of medicine, major efforts are currently dedicated to improve the clinical, physiological and therapeutic understanding of disease, and obstructive sleep apnoea (OSA) is no exception. The personalised medicine approach is relevant for OSA, given its complex pathophysiology and variable clinical presentation, the interactions with comorbid conditions and its possible contribution to poor outcomes. Treatment with continuous positive airway pressure (CPAP) is effective, but CPAP is poorly tolerated or not accepted in a considerable proportion of OSA patients. This review summarises the available studies on the p...
Source: European Respiratory Review - October 25, 2017 Category: Respiratory Medicine Authors: Bonsignore, M. R., Suarez Giron, M. C., Marrone, O., Castrogiovanni, A., Montserrat, J. M. Tags: Sleep medicine Personalised Medicine Source Type: research

Personalised medicine for nonsmall cell lung cancer
After years of standard care prescribed to cancer patients without any selection except the primary site and histology of the tumour, the era of precision medicine has revolutionised cancer care. Personalised medicine refers to the selection of patients for specific treatment based on the presence of specific biomarkers which indicate sensitivity to corresponding targeted therapies and/or lower toxicity risk, such that patients will have the greatest chance of deriving benefit from the treatments. Here, we review personalised medicine for nonsmall cell lung cancer.
Source: European Respiratory Review - November 15, 2017 Category: Respiratory Medicine Authors: Mascaux, C., Tomasini, P., Greillier, L., Barlesi, F. Tags: Pulmonary pharmacology and therapeutics, Lung cancer Personalised Medicine in Respiratory Diseases Source Type: research

Recommended Reading from Boston University School of Medicine Pulmonary and Critical Care Medicine Fellows.
PMID: 29155600 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - November 20, 2017 Category: Respiratory Medicine Authors: Abston ED, Hon SM, Berical A, Reardon CL Tags: Am J Respir Crit Care Med Source Type: research

Breaking the In Vitro Barrier in Respiratory Medicine: Engineered Microphysiological Systems for COPD and Beyond.
Abstract Chronic obstructive pulmonary disease (COPD) is a leading global health problem; however, our ability to understand the disease pathogenic processes and discover new pharmacotherapies have been significantly hindered due to lack of reliable model systems that are human-derived, physiologically more relevant, and can be applied predictively. Recent advances in microsystems engineering have made it possible to create biomimetic microfluidic cell culture devices, known as 'organs-on-chips'. In this Pulmonary Perspective, we discuss the emergence of 'Lung- and Small Airway-on-a-Chip' technologies and their ap...
Source: American Journal of Respiratory and Critical Care Medicine - December 20, 2017 Category: Respiratory Medicine Authors: Benam KH, Königshoff M, Eickelberg O Tags: Am J Respir Crit Care Med Source Type: research

In this issue of Occupational Medicine
A theme that frequently emerges in reviewing the new articles forOccupational Medicine is the extent to which specialists in occupational medicine are focused as much on the contribution of illness to the ability to work as we are on the effect of work exposures on the development of ill-health. Previous articles in this journal come to mind, in particular those addressing once fatal or incapacitating illnesses such as cancer or cystic fibrosis. They remind us that prior views on work ability have broadened through modern medicine ’s ability to effectively treat disease while at the same time preserving patients’ abili...
Source: Occupational Medicine - March 27, 2018 Category: Respiratory Medicine Source Type: research

Defining Impaired Respiratory Health: A Paradigm Shift for Pulmonary Medicine.
Abstract Respiratory research has historically focused on identifying risk factors for and treatment of established lung disease. Public health approaches to common conditions, however, mandate that health promotion is a central feature of disease prevention. While smoking initiation prevention and cessation efforts are essential to respiratory health promotion, there are far fewer accepted strategies of preventative care in respiratory medicine compared with cardiovascular medicine. A key reason for this is the absence of a comprehensive body of research guiding the assessment of risk for respiratory disease as h...
Source: American Journal of Respiratory and Critical Care Medicine - April 6, 2018 Category: Respiratory Medicine Authors: Reyfman PA, Washko GR, Dransfield MT, Spira A, Han MK, Kalhan R Tags: Am J Respir Crit Care Med Source Type: research

Precision medicine and personalising therapy in pulmonary hypertension: seeing the light from the dawn of a new era
This article aims to assemble and discuss the different initiatives that are currently underway in the PH/PAH fields together with the opportunities and prospects for their use in the near future.
Source: European Respiratory Review - April 13, 2018 Category: Respiratory Medicine Authors: Savale, L., Guignabert, C., Weatherald, J., Humbert, M. Tags: Pulmonary vascular disease Personalised Medicine in Respiratory Diseases Source Type: research

Recommendations Developed on Gender Equity in Medicine
ACP supports equitable physician compensation based on comparable work at each stage of career
Source: Pulmonary Medicine News - Doctors Lounge - April 17, 2018 Category: Respiratory Medicine Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Oncology, Ophthalmology, Orthopedics, ENT, Pathology Source Type: news

Precision medicine in COPD: where are we and where do we need to go?
Chronic obstructive pulmonary disease (COPD) was the fourth leading cause of death worldwide in 2015. Current treatments for patients ease discomfort and help decrease disease progression; however, none improve lung function or change mortality. COPD is heterogeneous in its molecular and clinical presentation, making it difficult to understand disease aetiology and define robust therapeutic strategies. Given the complexity of the disease we propose a precision medicine approach to understanding and better treating COPD. It is possible that multiOMICs can be used as a tool to integrate data from multiple fields. Moreover, a...
Source: European Respiratory Review - August 1, 2018 Category: Respiratory Medicine Authors: Sidhaye, V. K., Nishida, K., Martinez, F. J. Tags: COPD and smoking Personalised Medicine in Respiratory Disease Source Type: research

Steps Taken to Increase Use of Electronic Tools in Medicine
Docs will have more opportunity to use technology with extra codes approved by CPT Editorial Panel
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news

2019 Residency Match Day Was Largest in History
Internal medicine programs offered a record 8,116 categorical, 396 primary care positions
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Oncology, Ophthalmology, Orthopedics, ENT, Pathology Source Type: news

Doctors With Malpractice Claims More Likely to Leave Medicine
Physicians with five or more malpractice claims more than twice as likely to go into solo practice
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Oncology, Ophthalmology, Orthopedics, ENT, Pathology Source Type: news

Precision medicine in obstructive sleep apnoea
Publication date: Available online 12 April 2019Source: The Lancet Respiratory MedicineAuthor(s): Miguel Angel Martinez-Garcia, Francisco Campos-Rodriguez, Ferrán Barbé, David Gozal, Alvar AgustíSummaryObstructive sleep apnoea (OSA) is a heterogeneous and complex disease; however, diagnosis and management still rely on a simple set of tools and few therapeutic options. Precision medicine has emerged as the next goal for clinical practice, with the objective being to offer individually tailored treatments. Ways of implementing precision medicine in clinical practice have emerged for various respiratory disorders, and suc...
Source: The Lancet Respiratory Medicine - April 14, 2019 Category: Respiratory Medicine Source Type: research

Health Professionals Supportive of Medicinal Cannabis
However, across medicine, pharmacy, and nursing, providers need more information
Source: Pulmonary Medicine News - Doctors Lounge - November 11, 2014 Category: Respiratory Medicine Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news