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Researchers in the HIV Extinction Project at UCLA collaborate to cure AIDS
As we observe the 29th World AIDS Day, people infected with HIV are living longer than ever and progress continues in the fight against the disease that was a death sentence decades ago.Some of those positive developments resulted from research conducted at UCLA, where in 1981 doctors first sounded the alarm that a strange, new disease was sickening and killing people. Research at UCLA into models enabling tests for new drug therapies, the use of antiviral drugs to reduce mother-to-child HIV transmission, along with other developments, have contributed to a positive diagnosis for HIV no longer meaning an automatic death se...
Source: UCLA Newsroom: Health Sciences - December 2, 2016 Category: Universities & Medical Training Source Type: news
The World Health Organization Just Picked Its New Leaders. Most of Them Are Women
The World Health Organization announced its new senior leadership team Tuesday, and more than 60% of the appointees are women.
“The team represents 14 countries, including all WHO regions, and is more than 60% women, reflecting my deep-held belief that we need top talent, gender equity and a geographically diverse set of perspectives to fulfill our mission to keep the world safe,” WHO Director-General Dr. Tedros Adhanom Ghebreyesus said in a statement. The five men selected to lead the agency are Dr. Peter Salama, Dr. Bernhard Schwartländer, Dr. Ranieri Guerra, Dr. Ren Minghui, and Stewart Simonson.
WHO ...
Source: TIME.com: Top Science and Health Stories - October 4, 2017 Category: Consumer Health News Authors: Casey Quackenbush Tags: Uncategorized onetime United Nations women's empowerment Source Type: news
HPV Vaccination After Lesion Treatment Is Likely Cost - Effective
Adjuvant HPV vaccination could reduce anal cancer risk in HIV - infected men who have sex with men
Source: The Doctors Lounge - Oncology - March 28, 2017 Category: Cancer & Oncology Tags: Family Medicine, Infections, AIDS, Internal Medicine, Nursing, Oncology, Pathology, Pharmacy, Urology, Journal, Source Type: news
Lower-extremity Dynamometry as a Novel Outcome Measure in a Double-blind, Placebo-controlled, Feasibility Trial of Intravenous Immunoglobulin (IVIG) for HIV-associated Myelopathy
Conclusion: We conclude that an adequately powered clinical trial of IVIG for HIVM would likely require a prolonged recruitment period and multiple participating sites. Lower limb dynamometry is a useful outcome measure for HIVM, which might also be useful in other HIV-related gait disorders.
KEYWORDS: Dynamometry, intravenous immunoglobulin (IVIG), human immunodeficiency virus (HIV), myelopathy
INTRODUCTION
Human immunodeficiency virus (HIV)-associated myelopathy (HIVM) is a rare but well-described neurologic complication of HIV; it was first described early in the acquired immunodeficiency syndrome (AIDS) epidemic, and i...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools Current Issue Demyelinating Disease Movement Disorders Neurodegenerative Disease Neurology Original Research Primary Care Technology Trial Methodology Dynamometry human immunodeficiency virus (HIV) intravenous immu Source Type: research
AIDS Researcher Robert Redfield Is the New CDC Director. Here ’s Why the Pick Is Controversial
The Trump administration has tapped HIV researcher Dr. Robert Redfield to be the new leader of the U.S. Centers for Disease Control and Prevention (CDC),
Redfield will be replacing Dr. Brenda Fitzgerald, who stepped down from CDC director after Politico reported that she had bought shares in a tobacco company after accepting the position. Redfield will not require Senate confirmation.
However, reactions to his selection have been mixed.
Before joining the CDC, Redfield was a professor at the University of Maryland School of Medicine and the co-founder of the university’s Institute of Human Virology. Over his career, ...
Source: TIME: Health - March 22, 2018 Category: Consumer Health News Authors: Alexandra Sifferlin Tags: Uncategorized CDC CDC Director Dr. Robert Redfield healthytime public health Scientific misconduct Source Type: news
Viruses, Vol. 10, Pages 293: AIDS Clinical Research in Spain —Large HIV Population, Geniality of Doctors, and Missing Opportunities
Viruses, Vol. 10, Pages 293: AIDS Clinical Research in Spain—Large HIV Population, Geniality of Doctors, and Missing Opportunities
Viruses doi: 10.3390/v10060293
Authors:
Vicente Soriano
José M. Ramos
Pablo Barreiro
Jose V. Fernandez-Montero
The first cases of AIDS in Spain were reported in 1982. Since then over 85,000 persons with AIDS have been cumulated, with 60,000 deaths. Current estimates for people living with HIV are of 145,000, of whom 20% are unaware of it. This explains the still high rate of late HIV presenters. Although the HIV epidemic in Spain was originally driven mostly by injection drug u...
Source: Viruses - May 30, 2018 Category: Virology Authors: Vicente Soriano Jos é M. Ramos Pablo Barreiro Jose V. Fernandez-Montero Tags: Review Source Type: research
Use of Rostafuroxin to Inhibit Viral Infection
Acute respiratory infections during early childhood constitute a major human health burden. Human respiratory syncytial virus (RSV) is the most common and important viral cause of severe acute pediatric respiratory infections worldwide. Mortality due to RSV in the post-neonatal (28 days to 1 year old) population is second only to malaria. It is estimated that RSV causes 34 million lower respiratory tract infections, 4 million hospitalizations, and 66,000-199,000 deaths every year in children less than 5 years of age. Most mortality occurs in the developing world where clinical care is less accessible. Mortality is low in t...
Source: NIH OTT Licensing Opportunities - October 25, 2018 Category: Research Authors: ajoyprabhu3 Source Type: research
AACR: HPV Vax Low for Adults at High Risk for HIV Infection
Age, sex, sexual orientation differences in HPV vaccination rates were statistically significant
Source: The Doctors Lounge - Oncology - April 3, 2019 Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Infections, AIDS, Internal Medicine, Nursing, Oncology, Pharmacy, Conference News, Source Type: news
Zika Virus Potentiates the Development of Neurological Defects and Microcephaly: Challenges and Control Strategies
Conclusions
Apart West Nile virus (78), thousands of congenital microcephaly cases, fetal brain tissue damage and neurological syndromes have been associated with ZIKV infection. Unfortunately, the epidemics of this mosquito born, and a relative stable virus is on a rise. Although congenital microcephaly is a rare disorder however, due to lack of standardized diagnostic test facilities, the incidence in the geographically widespread ZIKV epidemic regions is higher. Animals studies showed that ZIKV is a neurotropic virus. It directly targets the developing embryonic brain cells by inducing apoptosis, cell-cycle arrest, and...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research
Case Study: Mechanism for Increased Follicular Helper T Cell Development in Activated PI3K Delta Syndrome
This study was carried out after written informed consent from all subjects. All subjects gave written informed consent in accordance with the Declaration of Helsinki. The protocol was approved by the Stanford University and UCLA Institutional Review Boards.
Author Contributions
MB provided patient care and obtained IRB approval. RO prepared histology images. MB, TT, and RB designed the research. TT and LP conducted experiments and analyzed data. MB made the molecular model. MB and TT wrote the manuscript.
Funding
Funding for this work came from the Jeffrey Modell Foundation and from the NIH/NIGMS (R01 GM110482 to MB)....
Source: Frontiers in Immunology - April 11, 2019 Category: Allergy & Immunology Source Type: research
HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients
In conclusion, we believe that the data presented in this research add new relevant information for a better definition of the pathological states associated with HTLV-1 infection, particularly in relation to the distinct subcellular expression of HBZ in the different pathological contests and related pathologies. Whether HBZ cytoplasmic and nuclear localization in the natural history of HTLV-1 infection represents a marker of infection or is part of the mechanism governing the evolution toward HAM/TSP or ATL is the challenge for future investigation.
Author Contributions
GF, MB, and RA conceived the work. GF, MB, and AT...
Source: Frontiers in Microbiology - April 25, 2019 Category: Microbiology Source Type: research
What Are Barriers and Facilitators of Transitioning Youth to an Adult Health Care Provider?
Discussion
Transitioning patients within or across health care facilities is a complex process. It is not a single step or point in time. For many patients the transition from pediatric to adult health care can be uncomplicated as patients and health care providers are ready for the transition and are seeking it. It should be a part of “developmental milestone” for adolescent visits. Asking adolescents about their future plans especially after high school or college often easily segues into this discussion easily. For other patients and families, there is anxiety and fear about the transition process. For yout...
Source: PediatricEducation.org - May 13, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Use of Rostafuroxin to Inhibit Viral Infection
Acute respiratory infections during early childhood constitute a major human health burden. Human respiratory syncytial virus (RSV) is the most common and important viral cause of severe acute pediatric respiratory infections worldwide. Mortality due to RSV in the post-neonatal (28 days to 1 year old) population is second only to malaria. It is estimated that RSV causes 34 million lower respiratory tract infections, 4 million hospitalizations, and 66,000-199,000 deaths every year in children less than 5 years of age. Most mortality occurs in the developing world where clinical care is less accessible. Mortality is low in t...
Source: NIH OTT Licensing Opportunities - October 25, 2018 Category: Research Authors: ajoyprabhu3 Source Type: research
Activists and LGBTQ Groups Say These Facebook Ads Spread Dangerous Misinformation About HIV Drugs
Advocacy groups are urging Facebook to remove advertisements that they say unfairly infer that the HIV/AIDS prevention Truvada PrEP (pre-exposure prophylaxis) is dangerous, an allegation they say could endanger the people who are most at risk of contracting the disease.
More than 50 HIV/AIDs, LGBTQ and public health advocacy groups released a letter on Monday asking Facebook and Instagram to remove the ads from their platforms.
The ads referred specifically to “Truvada PrEP” (the brand name for one of the medications, dtenofovir disoproxil fumarate, used as PrEP) and in some cases more generically to “PrE...
Source: TIME: Health - December 11, 2019 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized health LGBTQ onetime Source Type: news
What Causes Neutropenia?
Discussion
Neuropenia is defined as a neutrophil count < 1500/µL. It is classified as mild from 1000-1500/µL, moderate from 500-1000/µL, and severe if < 500/µL.
It is not uncommonly seen in the setting of acute self-limited infections, and with re-testing returns to normal. It is also not uncommon at certain ages, such as perinatally, especially in premature infants (up to 6%) . It is also common in certain ethnic groups particularly African American or Arabic populations where up to 10% of the children may have mild neutropenia which does not cause clinical disease. The overall prevalence a...
Source: PediatricEducation.org - March 2, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
