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Therapy: Corticosteroid Therapy

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Platelet rich plasma for the treatment of coccydynia: a case report and review of regenerative medicine for coccydynia.
Conclusion: Platelet rich plasma may be considered as a treatment option in patients with refractory coccydynia. PMID: 31960759 [PubMed - as supplied by publisher]
Source: Regenerative Medicine - January 20, 2020 Category: Genetics & Stem Cells Authors: Sussman WI, Jerome MA, Foster L Tags: Regen Med Source Type: research

Society for Maternal-Fetal Medicine Consult Series #58: Use of antenatal corticosteroids for individuals at risk for late preterm delivery: a response
The Society for Maternal-Fetal Medicine (SMFM), Publications Committee appreciates Dr Vidaeff and colleagues ’ interest in the SMFM Consult Series #58, “Use of antenatal corticosteroids for individuals at risk for late preterm delivery,”1 which reviews the available and often conflicting evidence regarding potential long-term neurodevelopmental risks of antenatal corticosteroids. We recommend that “ patients at risk of late preterm delivery be thoroughly counseled regarding the potential risks and benefits of antenatal corticosteroid administration and be advised that the long-term risks remain uncertain,” which ...
Source: American Journal of Obstetrics and Gynecology - January 24, 2022 Category: OBGYN Authors: Society for Maternal-Fetal Medicine, Publications Committee Tags: Letter to the Editors Source Type: research

Corticosteroids in Total Joint Arthroplasty: The Clinical Practice Guidelines of the American Association of Hip and Knee Surgeons, American Society of Regional Anesthesia and Pain Medicine, American Academy of Orthopaedic Surgeons, Hip Society, and Knee Society
The American Association of Hip and Knee Surgeons (AAHKS), The American Academy of Orthopaedic Surgeons (AAOS), The Hip Society, The Knee Society, and The American Society of Regional Anesthesia and Pain Medicine (ASRA) have worked together to develop evidence-based guidelines on the use of corticosteroids in primary total joint arthroplasty (TJA). The purpose of these guidelines is to improve the treatment of primary TJA patients and reduce practice variation by promoting a multidisciplinary, evidence-based approach to the use of corticosteroids following primary TJA.
Source: The Journal of Arthroplasty - August 13, 2022 Category: Orthopaedics Authors: Charles P. Hannon, Yale A. Fillingham, J. Bohannon Mason, Robert S. Sterling, AAHKS Anesthesia & Analgesia Clinical Practice Guideline Workgroup, William G. Hamilton, Craig J. Della Valle Tags: Practice Guidelines: American Association of Hip and Knee Surgeons, American Society of Regional Anesthesia and Pain Medicine, American Academy of Orthopaedic Surgeons, Hip Society, and Knee Society Source Type: research

Society for Maternal-Fetal Medicine Consult Series #67: Maternal sepsis
Maternal sepsis is a signi ficant cause of maternal morbidity and mortality, and is a potentially preventable cause of maternal death. This Consult aims to summarize what is known about sepsis and provide guidance for the management of sepsis during pregnancy and the postpartum period. Most studies cited are from the nonpreg nant population, but where available, pregnancy data are included. The following are the Society for Maternal-Fetal Medicine recommendations: (1) we recommend that clinicians consider the diagnosis of sepsis in pregnant or postpartum patients with otherwise unexplained end-organ damage in the presen c...
Source: American Journal of Obstetrics and Gynecology - May 24, 2023 Category: OBGYN Authors: Society for Maternal-Fetal Medicine (SMFM), Andrea D. Shields, Lauren A. Plante, Luis D. Pacheco, Judette M. Louis, SMFM Publications Committee Tags: SMFM Consult Series Source Type: research

What is the Differential Diagnosis of Multiple Fractures?
Discussion Bone mass, size and strength is at its peak in early adulthood. Multiple factors contribute to bone health including bone mass, hormonal balance, nutrition and weight bearing physical activity. Fractures are basically caused by too much force to be withstood by the bone. Abnormal momentary forces commonly occur in sports injuries such as this patient. When a child or young adult has several fractures, particularly clinically significant fractures, the possibility of an unidentified, underlying cause should be considered. According to the International Society for Clinical Densitometry, clinically significant fr...
Source: PediatricEducation.org - February 18, 2013 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Impaired Muscular Fat Metabolism in Juvenile Idiopathic Arthritis in Inactive Disease
Conclusion: Children with JIA show metabolic disturbance during exercise, even when the disease is considered inactive. This disturbance is seen in a lower lipid oxidation rate during submaximal exercise. Introduction In juvenile idiopathic arthritis (JIA), the most common rheumatoid disorder in pediatrics, an elevation of proinflammatory cytokines, such as IL-1β, IL-6, IL-8, or TNF-α, has been demonstrated in both the serum and synovial fluid of patients with JIA (Gorczyca et al., 2017). The highest cytokine levels were usually observed in the active phase of the disease, but they also stayed high in...
Source: Frontiers in Physiology - April 30, 2019 Category: Physiology Source Type: research

Similar clinical outcomes but more healthcare use in shoulder impingement patients following corticosteroid injection compared with physical therapy
Commentary on: Rhon DI, Boyles RB, Cleland JA. One-year outcome of subacromial corticosteroid injection compared with manual physical therapy for the management of unilateral shoulder impingement syndrome. Ann Intern Med 2014;161:161–9. Context Subacromial shoulder impingement syndrome (SIS) can cause shoulder problems and corticosteroid injections and physical therapy (exercise and manual therapy) are among the most common treatments. This randomised controlled trial (RCT) compares these treatments in adults with SIS. Methods This RCT recruited 104 patients with SIS who had been referred to physical therapy and who ...
Source: Evidence-Based Medicine - March 17, 2015 Category: Internal Medicine Authors: Foster, N. E. Tags: Rehabilitation medicine, Health informatics, Health policy, Clinical trials (epidemiology), General practice / family medicine, Pain (neurology), Degenerative joint disease, Musculoskeletal syndromes, Sports and exercise medicine, Health economics, Health Source Type: research

The Role of Physiatry in Regenerative Medicine: The Past, The Present, and Future Challenges
This article will also address the role physiatrists should have in the inevitable growth of regenerative medicine applications.
Source: PMandR - April 10, 2015 Category: Rehabilitation Source Type: research

Do Not Rush to Return to Sports After Trigger Finger Injection.
Abstract Trigger finger, or digital stenosing tenosynovitis, is a common hand problem. A widely accepted treatment is steroid injection into the flexor tendon sheath. This can cause rupture of the flexor tendon. However, to the best of our knowledge, there is no report on tendon rupture after a single corticosteroid injection. Moreover, there are no guidelines for patients with tendinopathy who want to return to sports after corticosteroid injection. Clinicians who perform local steroid injections for tendinopathy treatment should be aware of the possible dangers of tendon rupture and should confirm that steroids ...
Source: Medical Physics - March 19, 2015 Category: Physics Authors: Oh J, Jo L, Lee JI Tags: Am J Phys Med Rehabil Source Type: research

Ultrasound-guided corticosteroid injections for adhesive capsulitis more effective than placebo
Commentary on: Prestgaard T, Wormgoor ME, Haugen S, et al.. Ultrasound-guided intra-articular and rotator interval corticosteroid injections in adhesive capsulitis of the shoulder: a double-blind, sham-controlled randomized study. Pain 2015;156:1683–91. Context Adhesive capsulitis (frozen shoulder or painful stiff shoulder) is relatively common. It is idiopathic: known associated factors include trauma, diabetes, prolonged immobilisation, age, stroke and autoimmune disease. While self-limited, pain and decreased range of motion can last up to 2–3 years. Therefore, there is practical value in therapeutic in...
Source: Evidence-Based Medicine - March 21, 2016 Category: Internal Medicine Authors: Lebrun, C. M. Tags: Rehabilitation medicine, Immunology (including allergy), Pain (neurology), Stroke, Radiology, Degenerative joint disease, Musculoskeletal syndromes, Osteoarthritis, Sports and exercise medicine, Clinical diagnostic tests, Radiology (diagnostics), Screenin Source Type: research

What Type of Conservative Treatments Can Help for Plantar Fasciitis?
Discussion The plantar fascia consists of 3 bands of dense connective tissue that originates in the medical calcaneal tubercle and inserts into the base of each of the 5 proximal phalyanxes in a fan-shaped distribution. It acts as a shock absorber and reinforces the medial longitudinal arch as the foot undergoes forward propulsion. The -itis in plantar fasciitis (PF) is a misnomer as it is not an acute inflammation but is a chronic degenerative process involving the plantar fascia aponeurosis of the foot usually at the medial tubercle of the calcaneous. Repetitive strain seems to cause microtearing which then causes a repa...
Source: PediatricEducation.org - September 17, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Is This Bursitis?
Discussion Bursa are the body’s bumper pads for tendons. They are a small synovial fluid-filled sac that lies between tendon and a bone or skin. There are more than 150 of them in the body. With bursitis there can be thickening and proliferation of the synovial lining, bursal adhesions, chalky deposits and villus formation. Trauma, repetitive stress, infection and autoimmune usually are the reasons for bursitis but idiopathic etiology also occurs. The differential diagnosis includes infection, arthritis, tendonitis, tendon or ligament injury, fracture or neoplasm. The usual signs and symptoms are localized pain and t...
Source: PediatricEducation.org - November 3, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Komplikationen in der Therapie von Achillessehnenrupturen
Publication date: Available online 25 December 2014 Source:Sports Orthopaedics and Traumatology Sport-Orthopädie - Sport-Traumatologie Author(s): Lukas Weisskopf , Julian Röhm Achillessehnenrupturen gehören zu den häufigen Verletzungen der unteren Extremität bei sportlich ambitionierten Personen und Leistungssportlern mit hoher Komplikationsrate. Noch immer werden die verschiedenen Behandlungskonzepte, operativ vs. konservativ sowie minimal-invasiv vs. offen operativ, kontrovers diskutiert. Zu den Hauptkomplikationen gehört die Re-Ruptur der Achillessehne, wofür bei konservativer Therapie ein höheres Risiko beste...
Source: Sports Orthopaedics and Traumatology - December 25, 2014 Category: Sports Medicine Source Type: research

Longitudinal monitoring of endogenous steroids in human serum by UHPLC-MS/MS as a tool to detect testosterone abuse in sports.
Abstract The detection of testosterone abuse in sports is routinely achieved through the 'steroidal module' of the Athlete Biological Passport by GC-MS(/MS) quantification of selected endogenous anabolic androgenic steroids (EAAS) from athletes' urines. To overcome some limitations of the "urinary steroid profile" such as the presence of confounding factors (ethnicity, enzyme polymorphism, bacterial contamination, and ethanol), ultrahigh performance liquid chromatography (UHPLC) measurements of blood concentrations of testosterone, its major metabolites, and precursors could represent an interesting and complement...
Source: Analytical and Bioanalytical Chemistry - December 16, 2015 Category: Chemistry Authors: Ponzetto F, Mehl F, Boccard J, Baume N, Rudaz S, Saugy M, Nicoli R Tags: Anal Bioanal Chem Source Type: research

Clinical outcomes of non-operative treatment for patients presenting SLAP lesions in diagnostic provocative tests and MR arthrography
Conclusions Non-operative treatment with an appropriate regimen provided satisfactory clinical outcomes in middle-aged patients with symptomatic SLAP lesions and should be considered before recommending operative treatment. Clinical relevance Non-operative management using combined intra-articular corticosteroid injection with rotator cuff and periscapular strengthening exercises could be applied as primary treatment for patients with symptomatic SLAP lesion who participate in recreational level of sports. Level of evidence IV.
Source: Knee Surgery, Sports Traumatology, Arthroscopy - June 23, 2016 Category: Orthopaedics Source Type: research