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Shaped magnetic field pulses by multi-coil repetitive transcranial magnetic stimulation (rTMS) differentially modulate anterior cingulate cortex responses and pain in volunteers and fibromyalgia patients
Conclusion: Multi-coil rTMS may be a safe and effective treatment option for acute as well as for chronic pain, such as that accompanying fibromyalgia. Further studies are necessary to optimize configurations and settings as well as to elucidate the mechanisms that lead to the long-lasting pain control produced by these treatments.
Source: Molecular Pain - July 2, 2013 Category: Molecular Biology Authors: Alexander TzabazisCarina ApariciMichael RowbothamM SchneiderAmit EtkinDavid Yeomans Source Type: research

Exposure to Cold Unmasks Potential Biomarkers of Fibromyalgia Syndrome Reflecting Insufficient Sympathetic Responses to Stress
Discussion: The convergence of the effect of cold on 4 relatively simple measures of thermogenic, cardiovascular, and metabolic activity, each regulated by sympathetic activity, strongly indicate that individuals with FMS have impaired sympathetic responses to stress that are observable and highly significant even when measured in extraordinarily small sample populations. If insufficient sympathetic responses to stress are linked to FMS, stress may unmask and maximize these potential clinical biomarkers of FMS and be related to its etiology.
Source: The Clinical Journal of Pain - April 9, 2019 Category: Anesthesiology Tags: Original Articles Source Type: research

The impact of comorbid migraine on quality of life outcomes after endoscopic sinus surgery
Conclusion: Patients with comorbid migraine and CRS are more likely to have less severe evidence of disease and worse preoperative baseline QOL scores. This may imply that comorbid migraine disorder, in the setting of CRS, compels these patients to seek surgical management earlier in the disease process. Regardless, ESS provides comparable improvement for both patients with and without comorbid migraine.
Source: The Laryngoscope - January 15, 2014 Category: ENT & OMF Authors: Adam S. DeConde, Jess C. Mace, Timothy L. Smith Tags: Original Report Source Type: research

The impact of comorbid migraine on quality‐of‐life outcomes after endoscopic sinus surgery
ConclusionPatients with comorbid migraine and CRS are more likely to have less severe evidence of disease and worse preoperative baseline QOL scores. This may imply that comorbid migraine disorder, in the setting of CRS, compels these patients to seek surgical management earlier in the disease process. Regardless, ESS provides comparable improvement for both patients with and without comorbid migraine. Level of Evidence2c. Laryngoscope, 2014
Source: The Laryngoscope - February 20, 2014 Category: ENT & OMF Authors: Adam S. DeConde, Jess C. Mace, Timothy L. Smith Tags: Allergy/Rhinology Source Type: research

Fibromyalgia syndrome and cognitive dysfunction in elderly: a case series
ConclusionsNeurodegenerative disorders are rarely complicated by FMS, which is associated with relatively severe pain. Central sensitization may be a possible risk factor of widespread pain in elderly patients with NCD.
Source: APLAR Journal of Rheumatology - September 10, 2015 Category: Rheumatology Authors: Kenya Nishioka, Tetsuo Hayashi, Michimasa Suzuki, Yuanzhe Li, Sachiko Nakayama, Takashi Matsushima, Chie Usui, Nobuto Shibata, Yumiko Motoi, Ryota Tanaka, Kusuki Nishioka, Nobutaka Hattori Tags: Original Article Source Type: research

Clinically Diagnosed Acute Diverticulitis in Outpatients: Misdiagnosis in Patients with Irritable Bowel Syndrome
Conclusions Multiple types of indirect and concordant evidence suggest misattribution of IBS pain to diverticulitis and unnecessary antibiotic therapy in outpatients.
Source: Digestive Diseases and Sciences - October 6, 2015 Category: Gastroenterology Source Type: research

Transabdominal midline reconstruction by minimally invasive surgery: technique and results
Conclusion Although the study involved a small number of patients, it has proved the technique to be feasible, easy to perform, and have the combined benefits of laparoscopic and open surgery. The results, shown by CT-scan, peri-operative, and QOL findings, were good.
Source: Hernia - January 22, 2016 Category: Sports Medicine Source Type: research

Examination of high ‐antibiotic users in a multi‐institutional cohort of chronic rhinosinusitis patients
ConclusionVariability in antibiotic use in CRS appears to be driven by symptom burden, independent of objective measures of disease severity, patient demographics, and presence of comorbid disease. Clear guidelines are essential to define appropriate antibiotic use in CRS.
Source: International Forum of Allergy and Rhinology - December 31, 2016 Category: Allergy & Immunology Authors: Vijay R. Ramakrishnan, Jess C. Mace, Zachary M. Soler, Timothy L. Smith Tags: ORIGINAL ARTICLE Source Type: research

Back Pain in Children and Adolescents.
Abstract Back pain is a relatively common presenting symptom in children and adolescents. Typical causes include muscle strain or spasm, spinal deformities (e.g., Scheuermann kyphosis, adolescent idiopathic scoliosis), spondylolysis, bulging or herniated intervertebral disks, apophysitis of the iliac crest, and functional pain syndromes such as fibromyalgia. Spondyloarthropathies such as ankylosing spondylitis may present with low back pain and stiffness, which are often worse in the morning. Less common but more serious causes include malignancy and infections. The physical examination should include postural ins...
Source: American Family Physician - June 30, 2020 Category: Primary Care Authors: Achar S, Yamanaka J Tags: Am Fam Physician Source Type: research

Outcomes of Operatively Managed Lumbar and Sacral Facet Fractures in Pediatric Athletes: A Case Series
Conclusions: Athletes with localized back pain exacerbated by spine extension may have a facet fracture. As facet fractures are usually not identified with radiographs or MRI, a limited CT scan should be considered in the evaluation of pediatric athletes with localized back pain exacerbated by extension. In this series, surgical excision of facet fracture fragments was safe and provided predictable pain relief.
Source: Journal of Pediatric Orthopaedics - December 15, 2021 Category: Orthopaedics Tags: Sports Medicine Source Type: research