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NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Conclusion and Perspectives
Gliomas are the most prevalent primary brain cancer in adults and include a broad category of tumors including astrocytoma, oligodendroglioma, and GBM. Regardless of tumor aggressiveness, malignancy, and infiltration, these glia-derived tumors rarely exceed a median survival time of 12–14 months. Driven by the infiltrative nature of these tumors, the clinical approach is difficult and relapses often occur with fatal consequences. These unsuccessful attempts to control glioma's fate have fostered research looking for more effective therapies.
(GSCs) are a small subset of CD133&#...
Source: Frontiers in Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research
How Kidney Cancer Research Benefits From The American Recovery and Reinvestment Act of 2009
In this email to our CEO, Bill Bro, Shannon Bell, Director, Office of Advocacy Relations, at the National Cancer Institute, describes new initiatives in kidney cancer research. Mr. Bro will attend the National Cancer Advisory Board meetings, in Bethesda, in his capacity as a liaison representing cancer survivors.Dear Bill: I would like to take this opportunity to call your attention to several of NCI’s exciting initiatives funded through the American Recovery and Reinvestment Act of 2009 (ARRA) in both cancer research generally and in kidney cancer specifically. I am pleased to report that ...
Source: Kidney Cancer Association - February 28, 2010 Category: Urology & Nephrology Source Type: news
Economic evaluation of chelation regimens for β--thalassemia major: a systematic review
Conclusion:In brief, DFP is the best choice, followed by DFO or DFX, when an iron chelator is to be used alone for β-thalassemia major therapy. All studies that compared DFO and DFP combination therapy with DFO (or DFP or DFX) monotherapy established that the combination therapy with DFO and DFP was not cost-effective. However, due to the low number of related studies, more extensive, high-quality research is r equired for further analysis and confirmation of our findings. Moreover, the cost effectiveness is not an absolute issue when in different countries(regions) the results are opposite for other countries(regions). T...
Source: Mediterranean Journal of Hematology and Infectious Diseases - June 24, 2019 Category: Hematology Source Type: research
Trump Urges USPS and FedEx to Crackdown on Fentanyl Trafficking From China. They ’ve Been Trying for Years
With tensions over trade with China escalating, President Donald Trump said on Friday that he is “ordering” the U.S. postal service and express shipping companies to “SEARCH FOR & REFUSE all deliveries of fentanyl,” a deadly synthetic opioid. American officials have long blamed China for the influx of fentanyl and related drugs reaching U.S. borders — sent directly and trafficked via other countries — while federal efforts to limit (if not stop outright) their import have long been underway.
….your companies HOME and making your products in the USA. I will be responding to C...
Source: TIME: Health - August 24, 2019 Category: Consumer Health News Authors: Sanya Mansoor Tags: Uncategorized China Drugs White House Source Type: news
Polarized vs. Threshold Training Intensity Distribution on Endurance Sport Performance: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
The objective of this review was to systematically search the literature to identify and analyze data from randomized controlled trials that compare the effects of a polarized training model (POL) vs. a threshold training model (THR) on measurements of sport performance in endurance athletes. This systematic review and meta-analysis is registered with PROSPERO (CRD42016050942). The literature search was performed on November 6, 2016 and included SPORTDiscus (1800–present), CINAHL Complete (1981–present), and Medline with Full Text (1946–present). Studies were selected if they included: random allocation, endurance-tr...
Source: Journal of Strength and Conditioning Research - November 26, 2019 Category: Sports Medicine Tags: Brief Review Source Type: research
Formation of the component composition of blended hydrocarbon fuels as the problem of the multi-objective optimization
Publication date: 1 March 2020Source: Chemical Engineering Journal, Volume 383Author(s): E.D. Ivanchina, E.N. Ivashkina, V.A. Chuzlov, N.S. Belinskaya, A.Y. DementyevAbstractThe problem of energy efficiency has always been the most significant in the economy. Its solution is related to the technologies of many industries. The most significant are the reserves of energy efficiency of the use of hydrocarbon fuels, which are observed at all stages of production of high-energy hydrocarbon fuels. This is largely due to the extensive scientific search for alternative energy sources and stagnation in the conduct of search and fun...
Source: Chemical Engineering Journal - December 24, 2019 Category: Chemistry Source Type: research
Study: RSNA should tackle air travel carbon footprint
Airplane travel-related carbon dioxide emissions caused by the RSNA's annual...Read more on AuntMinnie.comRelated Reading:
Philips sets new carbon dioxide emission goals
Carestream reduces its environmental impact
Irish radiology department finds it's not easy being green
HIMSS: Clinton sees healthcare IT as global game changerComments:
2/21/2020 12:24:14 PMDoctorDalai
Seriously? Wonder what the city of Chicago might have to say about the impact of NOT having RSNA... The latest figures I could find with a fast google search were from 2007 (no doubt there are more recent numbers but I was too lazy to searc...
Source: AuntMinnie.com Headlines - February 21, 2020 Category: Radiology Source Type: news
7 Ways To Make The Most of Social Isolation
You're reading 7 Ways To Make The Most of Social Isolation, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles.
Social isolation is not ideal. It’s not good
for our individual physical health, mental health, or the global economy. But
right now it must be done for the collective wellbeing.
When cinemas, bars, restaurants and malls
close down and we’re obligated to stay inside, we need to find new ways to keep
ourselves entertained. However, it’s not just the entertainment that we miss.
The lubricant that keeps all ...
Source: PickTheBrain | Motivation and Self Improvement - March 27, 2020 Category: Consumer Health News Authors: Erin Falconer Tags: featured productivity tips psychology relationships self education self-improvement coronavirus covid_19 friendship isolation loneliness social distancing Source Type: blogs
The Facts About the L-1 Visa Program
ConclusionMultinational companies play an exceptionally important role in the United States. U.S. parent companies account for nearly a quarter of all private sector output, nearly half of all exports, and nearly three quarters of all private research and development.[44] More than 30 million American workers ’ jobs depend on multinationals. The U.S. government should not further upend investment and job growth by these companies in the United States during the economic recovery. The unemployment rate in computer occupations where many L‐1s are employed did not increase at all during the downturn,[45] and the Unit...
Source: Cato-at-liberty - June 10, 2020 Category: American Health Authors: David J. Bier Source Type: blogs
UAE ’s Mission to Mars Launches Successfully—a First for the Arab World
(TOKYO) — A United Arab Emirates spacecraft rocketed away Monday on a seven-month journey to Mars, kicking off the Arab world’s first interplanetary mission.
The liftoff of the Mars orbiter named Amal, or Hope, from Japan marked the start of a rush to fly to Earth’s neighbor that includes attempts by China and the United States.
The UAE said its Amal was functioning after launch as it heads toward Mars.
Omran Sharaf, the project director of Emirates Mars Mission, told journalists in Dubai about an hour and a half after the liftoff that the probe was sending signals. Sharaf said his team now would examine ...
Source: TIME: Science - July 19, 2020 Category: Science Authors: Mari Yamaguchi and Victoria Milko / AP Tags: Uncategorized News Desk overnight Space wire Source Type: news
Inside the Global Quest to Trace the Origins of COVID-19 —and Predict Where It Will Go Next
It wasn’t greed, or curiosity, that made Li Rusheng grab his shotgun and enter Shitou Cave. It was about survival. During Mao-era collectivization of the early 1970s, food was so scarce in the emerald valleys of southwestern China’s Yunnan province that farmers like Li could expect to eat meat only once a year–if they were lucky. So, craving protein, Li and his friends would sneak into the cave to hunt the creatures they could hear squeaking and fluttering inside: bats.
Li would creep into the gloom and fire blindly at the vaulted ceiling, picking up any quarry that fell to the ground, while his companion...
Source: TIME: Health - July 23, 2020 Category: Consumer Health News Authors: Charlie Campbell/ Yuxi, Yunnan and Alice Park Tags: Uncategorized COVID-19 feature Magazine Source Type: news
Coverage of the COVID-19 Pandemic in the Online Versions of Highly Circulated U.S. Daily Newspapers
AbstractWith the proliferation of news and the abundance of unknowns, COVID-19 information became rife with rumors and infiltrated consumers with confusion and information overload. In situations like this, it is important to provide consumers with credible and reliable information about the pandemic which is affecting their lives and livelihoods. Articles about coronavirus published in online versions of USA Today online, Wall Street Journal online and NYTimes.com between January and March 2020 were identified. Only articles where the search terms appeared in the headline were included as it was considered a more effectiv...
Source: Journal of Community Health - October 28, 2020 Category: International Medicine & Public Health Source Type: research
Occupational health of agricultural women workers in India
Conclusion: Implementation of social security and welfare measures by the Government for the agricultural women could enhance the health of women workers.
Source: Indian Journal of Community Medicine - October 28, 2020 Category: International Medicine & Public Health Authors: J Raja Meenakshi Sigamani Panneer Source Type: research
The Feds Come for Facebook
David BoazFacebook is under assault again, this time for real. The Federal Trade Commission and 46 states havefiled an antitrust case to make the company divest itself of Instagram and WhatsApp and submit to restrictions on its future acquisitions and deals.How many times have I seen this story play out as West Coast tech companies find themselves suddenly facing unwanted attention from Washington? It was bad enough that congressional committees kept summoning founder Mark Zuckerberg to hearings, both in ‐person and virtually, forcing him to trade his T‐shirt and hoodie for a suit and tie.Zuckerber...
Source: Cato-at-liberty - December 10, 2020 Category: American Health Authors: David Boaz Source Type: blogs
Leadership Mindset with an Emphasis in EMS, Part Three
Conclusion
“Half of what is taught in medical school is wrong, but nobody knows which half. –
Lucy Hornstein, MD.”15 The same could be said about leadership as well. Many leadership fads have been developed over time and may have had their place, but as times and trends change, so does leadership. As leaders in EMS, it’s crucial to adapt to the new generations of employees and identifying the best ways to work for and with them. The story of the blind men and the elephant is a good story to remember as leaders to say not all things that appear to be true necessarily are.
...
Source: JEMS Patient Care - December 17, 2020 Category: Emergency Medicine Authors: JEMS Staff Tags: Administration and Leadership Exclusives Adminstration & Leadership EMS Source Type: news
