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Positive topline phase III results show Roche ' s Vabysmo improved vision for people living with retinal vein occlusion (RVO)
Vabysmo achieved its primary endpoint of non-inferiority toaflibercept in RVO in the BALATON and COMINO clinical trialsVabysmo was generally well tolerated, with a safety profile consistent with previous trialsVabysmo is the first and only treatment that targets and inhibits two disease pathways involving Ang-2 and VEGF-A, linked to a number of vision-threatening retinal conditionsDetailed results will be presented at an upcoming medical meeting and submitted to regulatory authorities around the worldBasel, 27 October 2022 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from two global phase I...
Source: Roche Investor Update - October 27, 2022 Category: Pharmaceuticals Source Type: news

New phase III data show Roche ’s Vabysmo rapidly improved vision and reduced retinal fluid in people with retinal vein occlusion (RVO)
Vabysmo met its primary endpoint in two clinical trials, BALATON and COMINO, showing non-inferior visual acuity gains compared toafliberceptMoreVabysmo patients showed an absence of blood vessel leakage in the retina compared toaflibercept in a pre-specified exploratory endpointIf approved, RVO would be the third indication forVabysmo in addition toneovascular or ‘wet’ age-related macular degeneration and diabetic macular edemaBasel, 10 February 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive new data from two global phase III studies, BALATON and COMINO, evaluating Vabysmo ® (faricimab) in macular ...
Source: Roche Media News - February 10, 2023 Category: Pharmaceuticals Source Type: news

World ’s Deadliest Earthquake Leaves over 33,000 Dead
“A child in North Syria passing by the ruins, after the earthquake hit his town.” - Credit: Norwegian Refugee Council (NRC)By Sania FarooquiNEW DELHI, India, Feb 13 2023 (IPS) Almost over 33,000 people have been killed and thousands injured by the 7.8 earthquake which struck south-eastern Turkey and Syria in the early hours on Monday, February 6th. The first images that came out were of collapsed buildings, rubble strewn across streets, people trapped under rubbles, screaming for help. What followed was the unusually strong aftershock – including one quake which was almost as large as the first. Rawan Kahwaji wa...
Source: IPS Inter Press Service - Health - February 13, 2023 Category: International Medicine & Public Health Authors: Sania Farooqui Tags: Aid Featured Headlines Health Human Rights Humanitarian Emergencies Middle East & North Africa Migration & Refugees TerraViva United Nations IPS UN Bureau IPS UN Bureau Report Source Type: news

FDA accepts application for Roche ’s Vabysmo for the treatment of retinal vein occlusion (RVO)
Acceptance based on two phase III studies that demonstrated early and sustained vision improvement with Vabysmo, meeting primary endpoint of non-inferiority compared to afliberceptApplication was further supported by data showing Vabysmo achieved rapid and robust drying of retinal fluidIf approved, RVO would be the third indication for Vabysmo in addition to neovascular or ‘wet’ age-related macular degeneration (nAMD) and diabetic macular edema (DME)Vabysmo is currently approved in 60 countries to treat nAMD and DME, with nearly one million doses distributed globallyBasel, 9 May 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY...
Source: Roche Media News - May 9, 2023 Category: Pharmaceuticals Source Type: news

Clever Hans vs. the Fourth Amendment
Julian Sanchez In the early 1900s, the German public was fascinated by a mathematical Mr. Ed named Clever Hans, an Orlov Trotter horse that seemed to be capable of counting, doing basic arithmetic, and even solving elementary word problems—which, lacking the dexterity to grasp a number two pencil, it would answer by stamping its hooves. Eventually, of course, it was proven that Hans was doing nothing of the sort: the horse was perceptive rather than clever, and had been picking up on subtle, subconscious cues from his handler that let him know when to begin stamping and when (having arrived at the correct answer) he sho...
Source: Cato-at-liberty - February 19, 2013 Category: Health Medicine and Bioethics Commentators Authors: Julian Sanchez Source Type: blogs

"Balancing" and DNA Swabs
Julian Sanchez My colleagues Ilya, Jim, Roger, and Walter have said most of what needs to be said about the Supreme Court’s recent decision in the DNA sampling case Maryland v. King. So let me just hover for a moment on a point Roger makes.  Everyone seems to agree that Justice Kennedy’s majority opinion strains the bounds of language by arguing that the state purpose of “identification” served by DNA sampling arrestees includes establishing a “context” for understanding “who the person really is,” including their “past conduct.” By the same logic, we might justify searching the homes of e...
Source: Cato-at-liberty - June 5, 2013 Category: Health Medicine and Bioethics Commentators Authors: Julian Sanchez Source Type: blogs

...In Which Katz Is Not Cited
Jim Harper The Supreme Court is gradually coming to terms with the effect information technology is having on the Fourth Amendment. In 2001, the Kyllo court curtailed the use of high-tech devices for searching homes. In its early 2012 decision in United States v. Jones, a unanimous Court agreed that government agents can’t attach a GPS device to a vehicle and track it for four weeks without a warrant. But the Court was divided as to rationale. The majority opinion in Jones found (consistent with Cato’s brief) that attaching the device to the car was at the heart of the Fourth Amendment violation. Four concurri...
Source: Cato-at-liberty - March 11, 2014 Category: Health Medicine and Bioethics Commentators Authors: Jim Harper Source Type: blogs

The 4th Amendment Is Another Victim of the Drug War
Adam Bates Over at the Washington Post, Radley Balko details a recent Fourth Circuit ruling overturning an award for a father whose son was shot and killed in a military-style SWAT raid after marijuana residue was found in an outside garbage bag. A jury awarded the father $250,000 after it was shown that the police failed to comply with their obligation to knock and announce their presence before barging in and that they lied about several aspects of the raid. Without repeating the entirety of Balko’s excellent analysis, a particularly troubling aspect of the ruling is the nonchalant way in which the Fourth Circuit judg...
Source: Cato-at-liberty - March 27, 2015 Category: American Health Authors: Adam Bates Source Type: blogs

Meet The Real-Life Astronomer Who Inspired Jodi Foster's Character In 'Contact'
Are we alone in this vast cosmos? That's the burning question that drove Dr. Eleanor Arroway -- a fictional astronomer in Carl Sagan's book "Contact," who was played by Jodi Foster in the 1997 film adaptation -- on her epic quest for extra-terrestrial life. And it's also motivated the career of Dr. Jill Tarter, the real-life astronomer said to have inspired Arroway's character. (Story continues below image.) Jodi Foster as Dr. Eleanor Arroway in the film "Contact." Tarter retired in 2012 after spending 35 years scanning the skies for alien signals, and more than a decade as director of the Center for SETI (Search for E...
Source: Science - The Huffington Post - May 31, 2015 Category: Science Source Type: news

Fight Aging! Newsletter, May 9th 2016
This report is comprehensive and interested readers are encouraged to review. The authors provided projections on organ donation and transplantation rates, quality-adjusted life years and life years saved, health risks to patients, living organ donation, cross-border exchange, and health inequalities. Their most favorable scenario projected health benefits including transplanting up to 21,000 more organs annually in the EU, which would save 230,000 life years or gain 219,000 quality-adjusted life years (QALYs). For social impacts, it was predicted that increasing organ transplantation will have a positive effect on quality...
Source: Fight Aging! - May 8, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Senators Announce National USAR Response Act
WASHINGTON, D.C. - U.S. Senator Rob Portman (R-OH) announced that his National Urban Search and Rescue Response System Act, legislation that will strengthen the efficiency and effectiveness of the Federal Emergency Management Agency's (FEMA) disaster assistance capabilities and programs, was approved by the Homeland Security and Governmental Affairs Committee (HSGAC) today and is now ready for action by the full Senate. The bill also codifies protections for the search and rescue teams that respond to national emergencies such as 9/11, or Hurricanes Katrina and Sandy, making sure that the private citizens who leave their j...
Source: JEMS: Journal of Emergency Medical Services News - May 27, 2016 Category: Emergency Medicine Tags: News Source Type: news

Communications and Data Meet the Fourth Amendment
This week and last, the Cato Institutefiled amicus briefsurging the Supreme Court to take up two cases dealing with the constitutional status of “cell site location information,” or “CSLI.” This data, collected of necessity by cellular communications providers, creates detailed records of their customers’ movements. The briefs invite the Court to accept these cases so it can revise Fourth Amendment practice to eschew doctrine and m ore closely adhere to the language of the Fourth Amendment.The Fourth Amendment states that “[t]he right of the people to be secure in their persons, houses, papers, and effects, aga...
Source: Cato-at-liberty - November 3, 2016 Category: American Health Authors: Jim Harper Source Type: blogs