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Mental Health and Physical Activity among Children and Adolescents during the COVID-19 Pandemic
Tohoku J Exp Med. 2021;253(3):203-215. doi: 10.1620/tjem.253.203.ABSTRACTCoronavirus disease 2019 (COVID-19) is causing disruptions in the global social system. Japanese children and adolescents have had their schools closed, government-mandated activity restrictions imposed, and interactions outside the home reduced. These restrictions can have a considerable psychological impact on children and adolescents. This review aims to describe the impacts of COVID-19 pandemic on physical activity and psychological status of this population. The review was conducted by searching PubMed for information on the impact of COVID-19-re...
Source: The Tohoku Journal of Experimental Medicine - March 29, 2021 Category: Research Authors: Junko Okuyama Shuji Seto Yu Fukuda Shunichi Funakoshi Shintaro Amae Jun Onobe Shinichi Izumi Kiyoshi Ito Fumihiko Imamura Source Type: research

Are antiphospholipid antibodies just a common epiphenomenon or are they causative of immune-mediated coagulopathy in COVID-19?
AbstractThe coronavirus disease 2019 (COVID-19) is the largest public health emergency in recent times. A significant number of patients develop a severe form of COVID-19 characterized by coagulopathy, organ failure, and elevated mortality. In addition, an unusually high frequency of antiphospholipid antibodies (aPLs) has been found in patients with COVID-19. These clinical and serological manifestations closely resemble those seen in the antiphospholipid syndrome (APS), especially in its catastrophic form, suggesting a role of aPLs in immune-associated coagulopathy. However, government bodies such as the American Society ...
Source: Clinical Rheumatology - April 7, 2021 Category: Rheumatology Source Type: research

Fight Aging! Newsletter, May 3rd 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - May 2, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Coupons, PBM ' s ... oh my!
Over the past few years, my coverage of coupon-generating websites/apps has increased by a lot in this blog because those have emerged as a critical way for patients to get prescriptions at lower, PBM-negotiated prices even if they have yet to satisfy an annual insurance deductible or they have no insurance at all. In general, coupon-generating websites/apps offer consumers access to the deeper pharmacy benefits manager ( " PBM " )-negotiated prices on prescription drugs, at prices which are often substantially less than the prices you could otherwise attain as a consumer without the benefit of a commercial healthcare...
Source: Scott's Web Log - September 1, 2021 Category: Endocrinology Tags: CGM CGMS coupon-generating websites apps Dexcom insulin Libre PBM test strips Source Type: blogs

Turning PBM " Arbitrage " On Its Head: Bypassing Insurance to Save
The word of the day is " arbitrage " . Officially, Merriam-Webster defines the English language word " arbitrage " this way: " The nearly simultaneous purchase and sale of securities or foreign exchange in different markets in order to profit from price discrepancies " . However, arbitrage does not exclusively apply to securities sold on Wall Street. The term has also been adopted by the Pharmacy Benefit Manager ( " PBM " ) industry. But PBM ' s are not Wall Street investment banks. And that ' s something we all need to realize.The PBM Accountability Project 2021 report " Understanding the Evolving Business Model...
Source: Scott's Web Log - July 25, 2022 Category: Endocrinology Tags: 2022 arbitrage coupon-generating websites apps coupons Medicare PBM Source Type: blogs

FDA Building a Prescription Drug and Marketing Database
Over the last several years, we have written extensively about the potential implications that the Physician Payments Sunshine Act will have on physicians and the life sciences industry. One of the greatest implications is that numerous government and private entities will be able to use the publicly posted payment data to "data mine" for certain trends and information to identify potentially fraudulent behavior or medically unnecessary services. Living up to our predictions, although somewhat indirectly related to the Sunshine Act, the Food and Drug Administration's (FDA) Office of Criminal Investigations (OCI) recentl...
Source: Policy and Medicine - June 12, 2013 Category: Health Medicine and Bioethics Commentators Authors: Thomas Sullivan Source Type: blogs

Just Added: New Titles in the Lending Library
The National Network of Libraries of Medicine, South Central Region (NN/LM SCR) is happy to announce the addition of eight new titles to the Lending Library. New titles have been selected after review and are designed to support the mission of the NN/LM SCR. Books from the Lending Library may be requested by Network Members or those who are employed by Network Member institutions. This post provides an overview of the books which have been added. Visit the Lending Library page to request any of these exciting new titles. Archiving/Digitization Personal Archiving: Preserving Our Digital Heritage. Edited by Donald T. Hawkins...
Source: Network News - February 25, 2014 Category: Databases & Libraries Authors: Emily Hurst Tags: General (all entries) Lending Library Source Type: news

Riley and Wurie: Beyond "Get a Warrant"
Jim Harper As Ilya noted earlier, the Supreme Court struck a blow for privacy and the Fourth Amendment today. It ruled that a warrant is generally required when law enforcement officers want to search a cell phone they have seized. Justice Roberts’ opinion for a unanimous court provides some crisp language: Modern cell phones are not just another technological convenience. With all they contain and all they may reveal, they hold for many Americans “the privacies of life.” (citation omitted) The fact that technology now allows an individual to carry such information in his hand does not make the information any ...
Source: Cato-at-liberty - June 25, 2014 Category: American Health Authors: Jim Harper Source Type: blogs

Silent Killers Amidst The Fast And The Furious
Attention to Ebola is important. The virus’s ability to easily cross regional and national borders makes it a significant threat to global health and national security. The swift and aggressive international response to the 2014 outbreak of the Ebola virus, which has killed at least 10,000 people in Liberia, Sierra Leone, and Guinea, has been laudable and has resulted in positive outcomes, such as reduced disease transmission and strengthened global health and coordination systems. For example, staff from the Centers for Disease Control and Prevention in the United States, including those from various divisions at the Na...
Source: Health Affairs Blog - May 7, 2015 Category: Health Management Authors: Karen R. Siegel, K.M. Venkat Narayan and Christine Hancock Tags: Costs and Spending Featured Global Health Public Health chronic disease Diabetes Ebola H1N1 Source Type: blogs

Fight Aging! Newsletter, May 16th 2016
In this study the authors demonstrate that, as in many other cases, the methodology of delivery matters just as much as the details of the cells used: Retinal and macular degenerative diseases affect millions of people worldwide. Similar to other neurodegenerative diseases, there are no effective treatments that can stop retinal degeneration or restore degenerative retina. Recent advances in stem cell technology led to development of novel cell-based therapies, some are already in phase I/II clinical trials. Studies from our group and others suggest that human bone marrow-derived mesenchymal stem cells (hBM-MSC) m...
Source: Fight Aging! - May 15, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Law and Order? - Bristol-Myers-Squibb Settles Case Alleging Fraud and Kickbacks, No Admissions of Guilt, No Individuals Charged
Introduction   Donald Trump, Republican candidate for the US presidency last week announced he is the " law and order " candidate, accompanied by then vice presidential contender and New Jersey Governor Chris Christie. I wonder if all this interest in law and order will lead to increasing the effectiveness of enforcing laws when large US health care corporations are accused? For years, we have been watching a parade of legal settlements made by big US health care organizations.   These have included the biggest drug companies, biotechnology companies, device companies, insurance companies, etc, etc.   ...
Source: Health Care Renewal - July 21, 2016 Category: Health Management Tags: Abilify Bristol-Myers-Squibb crime impunity kickbacks legal settlements logical fallacies Source Type: blogs

UnitedHealth ' s Optum Division Settles Case Alleging it Enrolled Non-Terminally Ill Patients in Hospice, Thus Risking Their Deaths Due to Treatable Illnesses
Discussion The problem of fraudulant enrollment of non-terminal patients in hospice continues, despite our efforts over five years to make the problem more public.   The latest case involved a very big, very wealthy for-profit health care corporation which has had its share of troubles in the past .   Yet the latest case is as anechoic as earlier ones, including smaller cases this year. These enrollments may be motivated by the desire for more money, but they put patients at risk.   Nonetheless, such abuses by hospices get little press coverage, seemingly are ignored by health care regulators and law enf...
Source: Health Care Renewal - July 19, 2016 Category: Health Management Tags: fraud hospices legal settlements UnitedHealth Source Type: blogs

The Weird World of Data (and Your Privacy)
In 2007, Judge Richard Posnerfound it “untenable” that attaching a tracking device to a car is a seizure. But the Supreme Courtstruck down warrantless attachment of a GPS device to a car on that basis in 2012. Putting a tracking device on a car makes use of it without the owner ’s permission, and it deprives the owner of the right to exclude others from the car.The weird world of data requires us to recognize seizures when government agents take any of our property rights, including the right to use and the right to exclude others. There ’s more to property than the right to possession.In anamicus brief filed with ...
Source: Cato-at-liberty - August 30, 2016 Category: American Health Authors: Jim Harper Source Type: blogs

To Apply the Fourth Amendment in the Digital Age, Go Back to Its Text
Timothy Carpenter and Timothy Sanders were convicted in federal court on charges stemming from a string of armed robberies in and around the Detroit area. They appealed on the ground that the government had acquired detailed records of their movements through cell site location information ( “CSLI”) from their wireless carriers in violation of the Fourth Amendment. The U.S. Court of Appeals for the Sixth Circuit turned their appeal aside, finding that “[t]he government’s collection of business records containing these data … is not a search.”The Fourth Amendment states that “[t]he right of the people to be se...
Source: Cato-at-liberty - August 11, 2017 Category: American Health Authors: Ilya Shapiro Source Type: blogs

Gray literature: An important resource in systematic reviews
Abstract Systematic reviews aide the analysis and dissemination of evidence, using rigorous and transparent methods to generate empirically attained answers to focused research questions. Identifying all evidence relevant to the research questions is an essential component, and challenge, of systematic reviews. Gray literature, or evidence not published in commercial publications, can make important contributions to a systematic review. Gray literature can include academic papers, including theses and dissertations, research and committee reports, government reports, conference papers, and ongoing research, among others. I...
Source: Journal of Evidence-Based Medicine - August 31, 2017 Category: General Medicine Authors: Arsenio Paez Tags: METHODOLOGY Source Type: research