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Over-allotment takes Hancock Jaffe IPO to nearly $9m
The underwriter of an initial public offering by Hancock Jaffe Laboratories (NSDQ:HJLI) this week exercised in full its over-allotment option, taking the gross proceeds from the flotation to nearly $9 million.
The IPO, which priced on the last day of May, initially brought in $7.5 million for Irvine, Calif.-based Hancock Jaffe, which makes bioprosthetic implants designed to treat chronic deep vein insufficiency, heart valve conditions and coronary artery bypass grafts. The shares trade on the NASDAQ exchange under the symbol “HJLI.”
Network 1 Financial Securities, the offering’s managing underwriter, exercise...
Source: Mass Device - June 15, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Funding Roundup Initial Public Offering (IPO) Vascular Wall Street Beat hancockjaffelabs Source Type: news
Political Action Committee Funding: Where IR Lags Behind the Competition
Publication date: September 2018Source: Journal of Vascular and Interventional Radiology, Volume 29, Issue 9Author(s): Mario A. Cedillo, Mina S. Makary, Ajinkya S. Desai, Junjian Huang
Source: Journal of Vascular and Interventional Radiology - August 24, 2018 Category: Radiology Source Type: research
National Guideline Clearinghouse Is No More: Keep Calm and Search On.
Abstract
In July 2018, the National Guideline Clearinghouse lost funding, leaving fewer freely available online guideline collections. Based on the authors' experience of the 3 major guideline-focused databases that are currently available (Guidelines International Network, the Turning Research into Practice database, and Guideline Central) an easy to use resource with stringent inclusion criteria is currently lacking, though new resources are in development. These 3 resources vary in scope, and none stood out as an all-encompassing favorite. Regardless of the source used to find and access guidelines, clinicians ...
Source: The Annals of Pharmacotherapy - November 18, 2018 Category: Drugs & Pharmacology Authors: Gerberich A, Spencer S, Ipema H Tags: Ann Pharmacother Source Type: research
New Advances Along the Common Coagulation Pathway
Hemostasis is achieved through spatially and temporally regulated thrombin generation following vascular injury. Blood coagulation factor V plays an important role in this process as it has a major impact on thrombin production. FV is a large, heavily glycosylated protein sharing homology and domain organization with FVIII (A1-A2-B-A3-C1-C2). It is an inactive procofactor and must be cleaved by thrombin or other proteases to remove the B-domain to yield activated FV (FVa). FVa is a cofactor for FXa in the prothrombinase complex, the enzyme that activates prothrombin. Given the profound effect FVa has on thrombin formation,...
Source: Blood - November 21, 2018 Category: Hematology Authors: Camire, R. M. Tags: Vascular Biology Components of Hemostasis Source Type: research
One of the Ways Researchers Narrow the Search for Drugs to Slow Aging
Small molecule and drug candidate libraries are huge. Much of modern medical research is a process of screening subsets of those libraries in search of molecules that can produce benefits with minimal side-effects. Usually the output of a successful screen is taken as a starting point for further exploration and molecular tinkering, to improve the effect or minimize undesirable side-effects. The great hope for gene therapy is that it will render all of this largely obsolete by offering ways to directly influence a molecular mechanism to a configurable degree without meaningful side-effects. That remains a way off in the fu...
Source: Fight Aging! - January 18, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Corrigendum to ‘Anti-restenosis Treatment With Drug-Eluting or Covered Stents in Femoropopliteal Arterial Occlusive Disease: Evidence From a Comprehensive Network Meta-analysis’ European Journal of Vascular & Endovascular Surgery 58/1 (2019) 61 –74
The authors regret Missing mention the funding body of this work in the main text. This work was supported by a peripheral arterial disease research funds project from the local government agency “Guangzhou Municipal Science and Technology Bureau” (Funds information: Science and Technology Plan of Guangzhou, 201508020116). Thanks for the help of editors and officers and we are sorry for any inconvenience caused by this oversight.
Source: European Journal of Vascular and Endovascular Surgery - October 24, 2019 Category: Surgery Authors: Rongzhou He, Yanchen Ye, Zilun Li, Yu Jiang, Yonghui Li, Yunyan Liu, Kangjie Wang, Chen Yao Tags: Corrigendum Source Type: research
Notice of Special Interest (NOSI): Next-Generation Approaches to Renal Replacement Therapy Including Vascular Access
This NOSI aims to support the development of innovative approaches to renal replacement therapy and address critical accompanying challenges such as vascular access and fluid management during dialysis.Daniel Gossett, Ph.D. | NOT-DK-19-027
Source: NIDDK Funding Opportunities - October 9, 2019 Category: Endocrinology Source Type: funding
Kyruus receives $30 million for its search and scheduling platform
Kyruus, a provider search and scheduling tool for health systems, announced yesterday that it has garnered $30 million in funding from Francisco Partners.
In late December, Kyruus scored $42 million in Series D funding. With this new investment, the company ’s total funding is over $155 million.
WHAT THEY DO
Source: mobihealthnews - June 12, 2020 Category: Information Technology Source Type: news
The search for a Buruli Ulcer vaccine and the effectiveness of the Bacillus Calmette-Gu érin vaccine
Acta Trop. 2022 Jan 20;228:106323. doi: 10.1016/j.actatropica.2022.106323. Online ahead of print.ABSTRACTBuruli Ulcer is a neglected tropical disease that is caused by Mycobacterium ulcerans. It is not fatal; however, it manifests a range of devastating symptoms on the hosts' bodies. Various drugs and treatments are available for the disease; however, they are often costly and have adverse effects. There is still much uncertainty regarding the mode of transmission, vectors, and reservoir. At present, there are no official vector control methods, prevention methods, or a vaccine licensed to prevent infection. The Bacillus C...
Source: Acta Tropica - January 22, 2022 Category: Infectious Diseases Authors: Tamara Z Ishwarlall Moses Okpeku Adebayo A Adeniyi Matthew A Adeleke Source Type: research
Web of Science's Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor
Arterioscler Thromb Vasc Biol. 2022 Feb 3:ATVBAHA122317426. doi: 10.1161/ATVBAHA.122.317426. Online ahead of print.ABSTRACTThere are many metrics to evaluate the performance and status of journals. Among these, the journal impact factor (JIF) has become the dominant metric. The influence of JIF is illustrated by its widespread use to evaluate academic status, compensation, and funding decisions. However, as noted by Clarivate Analytics, the parent company of the web of science (WoS), the JIF should not be used without careful attention to the many phenomena that influence citation rates. To facilitate transparency, Clariva...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 3, 2022 Category: Cardiology Authors: Alan Daugherty Robert A Hegele Hong S Lu Nigel Mackman Daniel J Rader Christian Weber Source Type: research
Exploring links between hearing loss, dementia and the ‘cognitive reserve’ — plus the role of hearing aids
How does your hearing affect dementia risk? (Alzheimer’s Research UK):
With around 1 million people affected by dementia in the UK, and 12 million people estimated to have a type of hearing loss, it’s never been more important to understand this link.
One way that hearing loss and dementia could be linked is through our blood system.
Certain types of dementia, particularly vascular dementia, are caused when there is less blood flow reaching the brain. This can damage our brain cells. Recent studies have also shown that the parts of our brain that process sounds (our auditory system) have many blood vessels and are vuln...
Source: SharpBrains - February 10, 2022 Category: Neuroscience Authors: SharpBrains Tags: Brain/ Mental Health Alzheimer’s cognitive-reserve dementia hearing aids hearing loss vascular dementia Source Type: blogs
