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Fresh fruit consumption in relation to incident diabetes and diabetic vascular complications: findings from the China Kadoorie Biobank Study
Publication date: November 2016 Source:The Lancet Diabetes & Endocrinology, Volume 4, Supplement 1 Author(s): Huaidong Du, Liming Li, Derrick Bennett, Yu Guo, Iain Turnbull, Ling Yang, Fiona Bragg, Zheng Bian, Yiping Chen, Junshi Chen, Iona Millwood, Sam Sansome, Liangcai Ma, Ying Huang, Ningmei Zhang, Xiangyang Zheng, Qiang Sun, Timothy J Key, Rory Collins, Richard Peto, Zhengming Chen Background Although fresh fruit consumption has well recognised health benefits, substantial uncertainties remain about its potential effects on incident diabetes and, among those with diabetes, the risks of death and vascular comp...
Source: The Lancet Diabetes and Endocrinology - November 17, 2016 Category: Endocrinology Source Type: research
New Search Result Filters and Updated Reference List Display
As of August 2016, PMC is home tofour million articles! To make this wealth of
full-text content easier to navigate, PMC has rolled out a few updates:1) Search Result Filters On all search results pages, you will now see filters
(similar to PubMed ’s filters) on the left-hand side that allow you to filter your results by
article attributes, publication date, research funder, and search fields. These filters
replace the Limits page and allow you to more readily:find open access articles (PMC has more than 1.35 million open access articles that can
be reused according to their license statements),explo...
Source: PubMed Central News - August 17, 2016 Category: Databases & Libraries Source Type: news
Endometrial vascular development in heavy menstrual bleeding: altered spatio-temporal expression of endothelial cell markers and extracellular matrix components
This study was funded by Wellbeing of Women (RG1342) and Newcastle University. There are no competing interests to declare.TRIAL REGISTRATION NUMBERNot applicable.
Source: Human Reproduction - January 4, 2018 Category: Reproduction Medicine Source Type: research
Are there differences in parents ’ preferences and search processes across preschool types? Evidence from Louisiana
Publication date: 3rd Quarter 2018 Source:Early Childhood Research Quarterly, Volume 44 Author(s): Daphna Bassok, Preston Magouirk, Anna J. Markowitz, Daniel Player A rising proportion of four-year-olds now attend formal, or center-based, early childhood education (ECE) programs. Formal settings, such as Head Start, public preschool, and subsidized child care centers vary significantly in regulation, funding, and service provision. As these differences may have substantial implications for child development and family well-being, understanding how parents search for and select formal programs is critical. Using data from ...
Source: Early Childhood Research Quarterly - March 12, 2018 Category: Child Development Source Type: research
Are there differences in parents’ preferences and search processes across preschool types? Evidence from Louisiana
Publication date: 3rd Quarter 2018Source: Early Childhood Research Quarterly, Volume 44Author(s): Daphna Bassok, Preston Magouirk, Anna J. Markowitz, Daniel PlayerAbstractA rising proportion of four-year-olds now attend formal, or center-based, early childhood education (ECE) programs. Formal settings, such as Head Start, public preschool, and subsidized child care centers vary significantly in regulation, funding, and service provision. As these differences may have substantial implications for child development and family well-being, understanding how parents search for and select formal programs is critical. Using data ...
Source: Early Childhood Research Quarterly - July 5, 2018 Category: Child Development Source Type: research
MicroRNA-34a Promotes Vascular Cellular Senescence and Consequent Calcification
With the growing interest in the accumulation of senescent cells as an important cause of aging, and more funding flowing into this part of the field, researchers are uncovering numerous direct links between cellular senescence and age-related conditions. Senescent cells cause harm to tissues via their inflammatory secretions, the senescence-associated secretory phenotype (SASP). The SASP is damaging, but there are usually too few senescent cells, even in later life, to have a significant effect on tissue dysfunction through their localized actions. There may be exceptions to that rule, but the evidence to date strongly su...
Source: Fight Aging! - July 9, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care
Publication date: Available online 19 December 2014 Source:The Lancet Author(s): Timo Wolf , Gerrit Kann , Stephan Becker , Christoph Stephan , Hans-Reinhardt Brodt , Philipp de Leuw , Thomas Grünewald , Thomas Vogl , Volkhard A J Kempf , Oliver T Keppler , Kai Zacharowski Background In the current epidemic of Ebola virus disease in western Africa, many aid workers have become infected. Some of these aid workers have been transferred to specialised hospitals in Europe and the USA for intensified treatment, providing the potential for unique insight into the clinical course of Ebola virus disease under optimised supporti...
Source: The Lancet - December 20, 2014 Category: Journals (General) Source Type: research
The Use of Joint Incentive Funding to Create a Department of Veterans Affairs–Department of Defense Vascular Surgery Program
We report our experience in developing and sustaining a joint effort between the Department of Veterans Affairs (VA) and the Department of Defense (DOD) to create a vascular surgery program using joint incentive funding (JIF).
Source: JAMA Surgery - January 21, 2015 Category: Sports Medicine Source Type: research
More Details to Show How the Clearance of Senescent Cells Impacts Vascular Aging
Accumulation of senescent cells is one of the root causes of aging. Now that the scientific community has the means to selectively remove these unwanted cells, such as via the use of senolytic drugs, and now that funding has picked up for this field, researchers are rapidly quantifying specific links to the pathology of age-related disease. For example, earlier this year researchers demonstrated that clearance of senescent cells produces significant benefits to vascular health, slowing or reversing many of the aspects of aging in blood vessels, such as calcification and growth of atherosclerotic plaque. This more recently ...
Source: Fight Aging! - December 23, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Search strategies for finding systematic reviews: reply from authors.
This article is protected by copyright. All rights reserved.
PMID: 28339100 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - March 24, 2017 Category: Dermatology Authors: Gómez-García F, Ruano J, Aguilar-Luque M, Gay-Mimbrera J, Maestre-Lopez B, Sanz-Cabanillas JL, Carmona-Fernández PJ, González-Padilla M, Vélez García-Nieto A, Isla-Tejera B Tags: Br J Dermatol Source Type: research
The Vascular Bone Marrow Niche Influences Outcome in Chronic Myeloid Leukemia
The endosteal bone marrow niche is known to protect leukemic stem cells (LSC) from chemotherapy, but the role of the vascular niche in the bone marrow microenvironment in leukemia is largely unknown. E-selectin, which is expressed on bone marrow endothelial cells, has been described to regulate the dormancy of normal hematopoietic stem cells (HSC) by increasing HSC proliferation (Winkler IG, 2012). In chronic myeloid leukemia (CML), one of the myeloproliferative neoplasias caused by the oncogene BCR-ABL1, E-selectin (Krause DS, 2014) and the adhesion molecule CD44, which is overexpressed on CML-initiating cells (Krause DS,...
Source: Blood - November 21, 2018 Category: Hematology Authors: Godavarthy, P. S., Herkt, S., Hayduk, N., Weissenberger, E., Manavski, Y., Lucas, T., Pan, K.-T., Voutsinas, J. M., Wu, Q. V., Mueller, M. C., Oellerich, T., Oehler, V. G., Lausen, J., Krause, D. S. Tags: 506. Hematopoiesis and Stem Cells: Microenvironment, Cell Adhesion, and Stromal Stem Cells: Poster III Source Type: research
Something old, something new: digital quantification of uterine vascular remodelling and trophoblast plugging in historical collections provides new insight into adaptation of the utero-placental circulation
AbstractSTUDY QUESTIONWhat is the physiological extent of vascular remodelling in and trophoblast plugging of the uterine circulation across the first half of pregnancy?SUMMARY ANSWERAll levels of the uterine vascular tree (arcuate, radial and spiral arteries (SAs)) dilate ∼2.6- to 4.3-fold between 6 and 20 weeks of gestation, with significant aggregates of trophoblasts persisting in the decidual and myometrial parts of SAs beyond the first trimester.WHAT IS KNOWN ALREADYIn early pregnancy, endovascular trophoblasts form ‘plugs’ in the SAs, transiently inhibiting blood flow to the placenta, whilst concurrently the ...
Source: Human Reproduction - December 2, 2020 Category: Reproduction Medicine Source Type: research
UK scientists petition government for £1m to search for alien life
A group of British astronomers are hoping to launch a new mission to search for signs of extraterrestrial life in space. The group of scientists from 11 UK universities have dubbed themselves the UK Search for Extraterrestrial Intelligence (SETI) Research Network, and are currently petitioning the government for a small part of the UK’s science budget - £1m in annual funding.
Source: The Independent - Science - July 8, 2013 Category: Science Tags: Science Source Type: news
Blood and Vascular Systems Response to Sepsis (R01)
The objective of this initiative is to foster multi-disciplinary research projects needed to unravel the cellular and molecular mechanisms underlying the development of severe endothelial dysfunction that contributes to sepsis-related coagulopathy and vascular collapse. To accomplish this goal, the initiative will support research partnerships to conduct multi-disciplinary research needed to dissect the mechanisms of blood and vascular systems in sepsis pathogenesis
Source: Grants.gov - November 5, 2013 Category: Research Tags: Health Source Type: funding
