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Nutrition: Calcium
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Infrapopliteal calcification patterns in critical limb ischemia: diagnostic, pathologic and therapeutic implications in the search for the endovascular holy grail.
This article attempts to review the implications of the diverse pathologic patterns of calcium distribution in infrapopliteal vessels of CLI patients, on the diagnostic modalities, technological developments, and the evolution of therapeutic approaches to improve outcomes among these patients. A critical analysis of the currently available data is provided, pointing to the surprising omission on the role of calcium on outcomes, and future directions are discussed. Is infrapopliteal calcium a roadblock or the avenue towards new paths? Necessity remains the mother of invention.
PMID: 28240525 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - February 26, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Mustapha JA, Diaz-Sandoval LJ, Saab F Tags: J Cardiovasc Surg (Torino) Source Type: research
Calcium Administration During Weaning From Cardiopulmonary Bypass: A Narrative Literature Review
The search for safe and effective patient management strategies during weaning from cardiopulmonary bypass is ongoing; intravenous calcium is occasionally used as a first-line drug. The physiologic role of calcium suggests that it can support the function of the cardiovascular system during this critical period. Patients may be mildly hypocalcemic after cardiopulmonary bypass; however, this degree of hypocalcemia does not significantly impair the cardiovascular system. The transient beneficial effects of calcium administration (increase in arterial blood pressure, systemic vascular resistance, cardiac index, stroke volume,...
Source: Journal of Cardiothoracic and Vascular Anesthesia - July 23, 2019 Category: Anesthesiology Authors: Vladimir V. Lomivorotov, Elizaveta A. Leonova, Alessandro Belletti, Vladimir A. Shmyrev, Giovanni Landoni Tags: Review Article Source Type: research
Risk of non-typhoidal Salmonella vascular infections is increased with degree of atherosclerosis and inflammation: A multicenter study in southern Taiwan
CONCLUSION: Atherosclerosis of the aorta which is associated with a positive NTSVI score can predict the occurrence of vascular infections and serum IL-1β could be a biomarker for vascular infection in patients with NTS bacteremia.PMID:34301492 | DOI:10.1016/j.jmii.2021.04.007
Source: Journal of Microbiology, Immunology, and Infection - July 24, 2021 Category: Microbiology Authors: Ying-Wen Chen Hung-Jen Tang Yi-Shan Tsai Nan-Yao Lee Yuan-Pin Hung Chien-Fang Huang Ching-Chi Lee Chia-Wen Li Ming-Chi Li Ling-Shan Syue Shu-Li Su Shu-Hao Hsu Wen-Chien Ko Po-Lin Chen Source Type: research
Vascular calcium signaling and aging
This article is protected by copyright. All rights reserved.PMID:34705288 | DOI:10.1113/JP280950
Source: The Journal of Physiology - October 27, 2021 Category: Physiology Authors: Osama F Harraz Lars J ørn Jensen Source Type: research
SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein
Neurobiol Dis. 2021 Nov 13;161:105561. doi: 10.1016/j.nbd.2021.105561. Online ahead of print.ABSTRACTCoronavirus disease 19 (COVID-19) is a respiratory illness caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). COVID-19 pathogenesis causes vascular-mediated neurological disorders via elusive mechanisms. SARS-CoV-2 infects host cells via the binding of viral Spike (S) protein to transmembrane receptor, angiotensin-converting enzyme 2 (ACE2). Although brain pericytes were recently shown to abundantly express ACE2 at the neurovascular interface, their response to SARS-CoV-2 S protein is still to be elucid...
Source: Neurobiology of Disease - November 15, 2021 Category: Neurology Authors: Rayan Khaddaj-Mallat Natija Aldib Maxime Bernard Anne-Sophie Paquette Aymeric Ferreira Sarah Lecordier Armen Saghatelyan Louis Flamand Ayman ElAli Source Type: research
CCAAT/Enhancer-Binding Protein Alpha Is a Novel Regulator of Vascular Smooth Muscle Cell Osteochondrogenic Transition and Vascular Calcification
CONCLUSION: Findings in this study indicate that C/EBPα is a key regulator of the osteochondrogenic transdifferentiation of VSMCs and vascular calcification, which may represent a novel therapeutic target for vascular calcification.PMID:35295585 | PMC:PMC8918665 | DOI:10.3389/fphys.2022.755371
Source: Atherosclerosis - March 17, 2022 Category: Cardiology Authors: Pengyuan Chen Wanzi Hong Ziying Chen Flora Gordillo-Martinez Siying Wang Hualin Fan Yuanhui Liu Yining Dai Bo Wang Lei Jiang Hongjiao Yu PengCheng He Source Type: research
