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Effects of taurine on vascular tone
Amino Acids. 2022 Aug 19. doi: 10.1007/s00726-022-03198-6. Online ahead of print.ABSTRACTTaurine is widely distributed at high concentrations in mammalian tissues, and it plays an important role in a wide range of biological effects including modulation of cardiovascular functions. This review summarizes the role of taurine in vascular tone and blood pressure modulation based on experimental and human studies. It is well established that supplementation of taurine prevents development of hypertension in several animal models and p.o. taurine administration reduces blood pressure in hypertensive patients. Both central and p...
Source: Amino Acids - August 19, 2022 Category: Biochemistry Authors: Oguzhan Yildiz Kemal Gokhan Ulusoy Source Type: research

An interview with Reyna Favis, author of Soul Search
Hi everyone, and this week I’d like to introduce Reyna Favis to the Thursday Throng. Reyna spent more than a dozen years as a drug development genomics scientist before turning to write fiction full-time. Her previous publishing history includes scholarly articles. When not writing, she responds to callouts as a canine handler for search and rescue. She lives in Warren County New Jersey with her husband, a search dog and a coterie of pets. What is one thing that no-one would usually know about you? I used to work for corporate America and I once gave a presentation where the introductory slide borrowed heavily fro...
Source: The Hysterectomy Association - February 2, 2017 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Interviews author interview Source Type: news

A multi-target protective effect of Danggui-Shaoyao-San on the vascular endothelium of atherosclerotic mice
CONCLUSIONS: Collectively, DGSY can alleviate vascular endothelium damage and delay the occurrence of AS, and the underlying mechanism may be related to the multi-target protective of DGSY.PMID:36803348 | DOI:10.1186/s12906-023-03883-3
Source: Atherosclerosis - February 21, 2023 Category: Cardiology Authors: Yuemeng Sun Yushan Gao Lu Zhou Yixing Lu Yulin Zong Haoyu Zhu Yang Tang Fengjie Zheng Yan Sun Yuhang Li Source Type: research

Chemerin is resident to vascular tunicas and contributes to vascular tone
Am J Physiol Heart Circ Physiol. 2023 Jun 9. doi: 10.1152/ajpheart.00239.2023. Online ahead of print.ABSTRACTThe adipokine chemerin may support blood pressure, evidenced by a fall in mean arterial pressure after whole body antisense oligonucleotide (ASO)-mediated knockdown of chemerin protein in rat models of normal and elevated blood pressure. While the liver is the greatest contributor of circulating chemerin, liver-specific ASOs that abolished hepatic-derived chemerin did not change blood pressure. Thus, other sites must produce the chemerin that supports blood pressure. We hypothesize the vasculature as a source of che...
Source: American Journal of Physiology. Heart and Circulatory Physiology - June 9, 2023 Category: Physiology Authors: Emma Wabel Alexis Orr Emma D Flood Janice M Thompson Huirong Xie Elena Y Demireva Bana Abolibdeh Darcy Honke Hulbert Adam E Mullick Hannah Garver Gregory D Fink Theodore A Kung Stephanie W Watts Source Type: research