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Evaluation of Vascular Health of E-Beta Thalassemia Patients: Effect of Iron Overload
J Assoc Physicians India. 2021 Nov;69(11):11-12.ABSTRACTHb E-β thalassemia is the most common form of hemoglobinopathy in Southeast Asia and eastern India. Iron overload resulting from blood transfusion and increased intestinal iron absorption promotes the formation of reactive oxygen species (ROS), leading to oxidative stress, organ dysfunction, and tissue damage. Of these, cardiovascular complications are the leading cause of mortality. Impaired endothelial function is a biomarker of vascular health in patients with cardiovascular risks. Therefore, assessment of endothelial function is a useful prognostic tool. In the p...
Source: Journal of the Association of Physicians of India - November 16, 2021 Category: General Medicine Authors: Dibyendu De Uttam Kumar Nath Prantar Chakrabarti Source Type: research
