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Dr. Epstein, Political Bias, & Google Search Results
I’m a little confused by claims made by Dr. Robert Epstein and his assertion, based upon a single study of 95 participants, that Google somehow intentionally biased the results shown before the 2016 U.S. presidential election. And therefore, likely impacted the election results itself. That’s a huge assertion to make. One would hope that an esteemed researcher such as Dr. Epstein would have the scientific data to back it up. Unfortunately, I don’t see it. Science is only objective up until the point where a scientist acknowledges and accounts for her or his own biases. Science is not based on a preset ag...
Source: World of Psychology - August 22, 2019 Category: Psychiatry & Psychology Authors: John M. Grohol, Psy.D. Tags: General Policy and Advocacy Psychology Technology google bias Robert Epstein Source Type: blogs

The SMILES Substructure Search Fallacy
ConclusionText matching on SMILES strings seems like a natural, simple solution to the substructure search problem. But this is a mirage. The futility of this approach may only become apparent after weeks or even months of effort. Regardless of the specific implementation, any robust solution must compare molecules as graphs.
Source: Depth-First - April 13, 2019 Category: Chemistry Authors: Richard L. Apodaca Source Type: blogs

More tusk than musk – a Mastodon FAQ
What is Mastodon? Mastodon is an alternative social media system comprising lots of different interconnected sites, each with its own specific interests, but all running the open-source Mastodon software, which makes them all function in roughly the same way and allows communication and sharing between users. When was it started? Mastodon was started in March 2016, but gained a lot of new interest in April 2022 and again in November 2022 in the wake of major changes at one of the more well-known social media systems, Twitter. Technically, how is Mastodon different? First off, Mastodon is not a single service in the way tha...
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 21, 2022 Category: Science Authors: David Bradley Tags: Social Media Source Type: blogs

Less Musk, More Tusk – a Mastodon FAQ
What is Mastodon? Mastodon is an alternative social media system comprising lots of different interconnected sites, each with its own specific interests, but all running the open-source Mastodon software, which makes them all function in roughly the same way and allows communication and sharing between users. When was it started? Mastodon was started in March 2016, but gained a lot of new interest in April 2022 and again in November 2022 in the wake of major changes at one of the more well-known social media systems, Twitter. Why is it called Mastodon? Apparently, it’s named after the American rock band of that name....
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 21, 2022 Category: Science Authors: David Bradley Tags: Social Media Source Type: blogs

Mastodon FAQ – Less Musk, More Tusk
What is Mastodon? Mastodon is an alternative social media system comprising lots of different interconnected sites, each with its own specific interests, but all running the open-source Mastodon software, which makes them all function in roughly the same way and allows communication and sharing between users. When was it started? Mastodon was started in March 2016, but gained a lot of new interest in April 2022 and again in November 2022 in the wake of major changes at one of the more well-known social media systems, Twitter. Why is it called Mastodon? Apparently, it’s named after the American rock band of that name....
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 21, 2022 Category: Science Authors: David Bradley Tags: Social Media Source Type: blogs

Publisher Correction: Controlling an organic synthesis robot with machine learning to search for new reactivity
Publisher Correction: Controlling an organic synthesis robot with machine learning to search for new reactivity, Published online: 24 July 2018; doi:10.1038/s41586-018-0412-8Publisher Correction: Controlling an organic synthesis robot with machine learning to search for new reactivity
Source: Nature AOP - July 24, 2018 Category: Research Authors: Jaros ław M. Granda Liva Donina Vincenza Dragone De-Liang Long Leroy Cronin Source Type: research

Exposure to persistent organic pollutants and thyroid cancer risk: a study protocol of systematic review and meta-analysis
Introduction The thyroid cancer incidence has been increasing all over the world. However, the aetiology of thyroid cancer remains unclear. A growing body of evidence suggested exposure to persistent organic pollutants (POPs) may play a role in the initiation of thyroid cancer, but the results are generally inconsistent across studies. This review aims to synthesise the evidence for the health effects of POPs on the risk of thyroid cancer. Methods and analysis This protocol was reported in accordance to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA) statements. A comprehensive se...
Source: BMJ Open - August 18, 2021 Category: General Medicine Authors: Zhang, Y. X., Liu, Y. P., Miao, S. S., Liu, X. D., Ma, S. M., Qu, Z. Y. Tags: Open access, Public health Source Type: research

Global Minimum Search and Bonding Analysis of Tl2Hx and Tl3Hy (x=0-6; y=0-5) Series
Chemphyschem. 2023 Jun 2:e202300332. doi: 10.1002/cphc.202300332. Online ahead of print.ABSTRACTA remarkable comparison of Boron and Carbon hydrides can be expressed in extremely different bonding patterns and chemical reactivity, which ultimately leads to different areas of applications. Particularly, Carbon, based on classical two-center - two-electron bonds, gives rise to organic chemistry. Oppositely, Boron produces many exotic and somewhat non-intuitive compounds collectively called non-classical structures. It's natural to expect other elements of Group 13 to possess their own unusual bonding patterns; however, our k...
Source: Chemphyschem - June 2, 2023 Category: Chemistry Authors: Anton S Pozdeev Pavel Rublev Alexander I Boldyrev Yi Rao Source Type: research

Identification of novel non-ionic, cationic, zwitterionic, and anionic polyfluoroalkyl substances using UPLC-TOF-MS(E) high-resolution parent ion search.
This study presents a time-of-flight mass spectrometry approach based on continuously interleaving scans at low and high collision energies (ToF-MS(E)) for the rapid identification and characterization of unknown PFASs. The MS(E) mode allowed for the simultaneous acquisition of full-spectrum accurate mass data of both parent and fragment ions in a single chromatographic run. Specific to PFASs, the hypothesis that PFASs can be selectively detected by the ToF-MS(E) high-resolution parent-ion search (HRPIS) of their characteristic fragments was confirmed with certified standards of 24 poly- and per-PFAS. After being validated...
Source: Analytica Chimica Acta - September 18, 2017 Category: Chemistry Authors: Xiao F, Golovko SA, Golovko MY Tags: Anal Chim Acta Source Type: research

Prebiotic Chemistry of HCN Tetramerization by Automated Reaction Search.
We report an explorative study based on automated reaction search method that avoid the cognitive bias in searching the chemical reaction space. We have discussed the chemical space of HCN dimer elaborately, and the important trimers and tetramers are discussed briefly. A component wise molecular fingerprint based methodology is proposed for identifying molecular similarity. Overall, we present four different thermal routes to cis/trans-2,3-diaminomaleonitrile and 4-aminoimidazole-5-carbonitrile, the important intermediates in the prebiotic chemistry. PMID: 29369429 [PubMed - as supplied by publisher]
Source: Chemistry - January 25, 2018 Category: Chemistry Authors: Nandi S, Bhattacharyya D, Anoop A Tags: Chemistry Source Type: research

Search of non-ionic surfactants suitable for micellar liquid chromatography.
Abstract Most reports in reversed-phase liquid chromatography (RPLC) with micellar mobile phases make use of the anionic sodium dodecyl sulfate. This surfactant masks efficiently the silanol groups that are the origin of the poor efficiencies and tailing peaks observed for basic compounds in conventional RPLC. However, it has the handicap of yielding excessive retention, which forces the addition of an organic solvent to reduce the retention times to practical values. Other surfactants, such as the non-ionic polyoxyethylene(23)lauryl ether (Brij-35), are rarely used. Brij-35 allows the separation of a large range ...
Source: Analytical and Bioanalytical Chemistry - June 19, 2018 Category: Chemistry Authors: Peris-García E, Rodríguez-Martínez J, Baeza-Baeza JJ, García-Alvarez-Coque MC, Ruiz-Angel MJ Tags: Anal Bioanal Chem Source Type: research

Controlling an organic synthesis robot with machine learning to search for new reactivity
Controlling an organic synthesis robot with machine learning to search for new reactivity, Published online: 18 July 2018; doi:10.1038/s41586-018-0307-8A robot instructed by a machine learning algorithm and coupled with real-time spectroscopic systems provides fast and accurate reaction outcome predictions and reactivity assessments, leading to the discovery of new reactions.
Source: Nature AOP - July 18, 2018 Category: Research Authors: Jaros ław M. Granda Liva Donina Vincenza Dragone De-Liang Long Leroy Cronin Source Type: research

Evaluation of Antimicrobial Activity of Four Organic Acids Used in Chicks Feed to Control Salmonella typhimurium: Suggestion of Amendment in the Search Standard.
Authors: El Baaboua A, El Maadoudi M, Bouyahya A, Belmehdi O, Kounnoun A, Zahli R, Abrini J Abstract Today, the general public has become increasingly aware of salmonellosis problems. Organic acids are known by their antimicrobial potential and commonly used for improving the quality of poultry feed. In this context, the present work evaluated the inhibitory effect of four organic acids, namely, acetic acid, citric acid, lactic acid, and tartaric acid, at different levels of contamination by Salmonella typhimurium. The neutralization of these organic acids in vitro and in the presence of one-day-old chick's organs ...
Source: International Journal of Microbiology - October 28, 2018 Category: Microbiology Tags: Int J Microbiol Source Type: research

Smiths Group unveils Smiths Medical spinout plan, search for new CEO
Smith Medical parent company Smiths Group (LON:SMIN) today announced plans to pursue a demerger with its Smiths Medical business, which will become separately listed in the UK. Smiths Group said it believes the demerger will strengthen both companies and allow the newly separated medical business to better capitalize on its leading positions, product launches and other value-creating opportunities. The company said it expects to complete the demerger some time during the first half of next year. “Pursuing a demerger of Smiths Medical will lead to two stronger companies each focusing on accelerating the execution of...
Source: Mass Device - March 22, 2019 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Featured Wall Street Beat Smiths Group plc Smiths Medical Source Type: news

Galvanic Skin Response (GSR)/Electrodermal/Skin Conductance Biofeedback on Epilepsy: A Systematic Review and Meta-Analysis
Conclusion Despite the above limitations, this systematic review supports a view that modulation of sympathetic activity using GSR biofeedback represents a promising new therapeutic tool for management of seizures in patients with epilepsy. For future clinical trials, important elements to be considered include size of patient population, seizure type, double-blinding, inclusion of an appropriate control group, and robust randomization methods. Ethics Statement We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidel...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research