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Total 19098 results found since Jan 2013.

The effect of pharmacologic treatment of migraine on retinal vasculature
Eur J Ophthalmol. 2021 Jun 27:11206721211028036. doi: 10.1177/11206721211028036. Online ahead of print.NO ABSTRACTPMID:34180270 | DOI:10.1177/11206721211028036
Source: European Journal of Ophthalmology - June 28, 2021 Category: Opthalmology Authors: Joshua P Harvey Source Type: research

Response to the effect of pharmacologic treatment of migraine on retinal vasculature
Eur J Ophthalmol. 2021 Jun 27:11206721211028042. doi: 10.1177/11206721211028042. Online ahead of print.NO ABSTRACTPMID:34180258 | DOI:10.1177/11206721211028042
Source: European Journal of Ophthalmology - June 28, 2021 Category: Opthalmology Authors: Julio Gonz ález-Martín-Moro Jes ús Porta Etessam Bel én Pilo de la Fuente Irene Fuentes Vega In és Contreras Source Type: research

Automatic segmentation of retinal layer boundaries in OCT images using multiscale convolutional neural network and graph search
Publication date: Available online 30 July 2019Source: NeurocomputingAuthor(s): Kai Hu, Binwei Shen, Yuan Zhang, Chunhong Cao, Fen Xiao, Xieping GaoAbstractAccurate quantitative analysis of the retinal layer in optical coherence tomography (OCT) images plays a crucial role in detecting and diagnosing ocular diseases. In this paper, we present a novel automatic method by combining multiscale convolutional neural network (MCNN) and graph search to accurately segment multiple retinal layer boundaries in OCT images. Firstly, we propose a MCNN architecture to extract multiscale features of retinal layer boundaries and thus to p...
Source: Neurocomputing - July 31, 2019 Category: Neuroscience Source Type: research

Automatic Anisotropic Diffusion Filtering and Graph-search Segmentation of Macular Spectral-domain Optical Coherence Tomographic (SD-OCT) Images.
CONCLUSION: Segmentation was evaluated using manually segmented B-scan by an Ophthalmologist as ground truth and accuracy was found to be 99.14 ± 0.27%. PMID: 31989882 [PubMed - in process]
Source: Current Medical Imaging Reviews - January 30, 2020 Category: Radiology Tags: Curr Med Imaging Rev Source Type: research

Search for the Source of the Retinal Relaxing Factor.
CONCLUSIONS: the RRF is not released from vascular cells and probably neither from glial cells. The retinal cell type which does release the RRF remains unclear. Veratridine does not stimulate the RRF release in mice and the RRF release in chickens is calcium-dependent as well as calcium-independent. PMID: 29966443 [PubMed - as supplied by publisher]
Source: Current Eye Research - July 2, 2018 Category: Opthalmology Authors: Vanden Daele L, Boydens C, Devoldere J, Remaut K, Van de Voorde J Tags: Curr Eye Res Source Type: research

Investigating Zebrafish Biochemistry in Search of Mechanisms of Neural Regeneration
Zebrafish are highly regenerative, capable of regrowing organs, and even nervous system tissue such as the retina. Research groups investigate these species in search of specific mechanisms of proficient regeneration, with the hope that they can be ported over to human biochemistry. In the best case scenario, mechanisms of this nature could still exist in mammals, retained in order to conduct embryonic development, but actively suppressed in some way in adults, possibly because such suppression reduces cancer risk. The existing evidence is suggestive that this is the case, and the work here adds further support. R...
Source: Fight Aging! - October 16, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Molecular regulation of neuroinflammation in glaucoma: Current knowledge and the ongoing search for new treatment targets
Prog Retin Eye Res. 2021 Aug 1:100998. doi: 10.1016/j.preteyeres.2021.100998. Online ahead of print.ABSTRACTNeuroinflammation relying on the inflammatory responses of glial cells has emerged as an impactful component of the multifactorial etiology of neurodegeneration in glaucoma. It has become increasingly evident that despite early adaptive and reparative features of glial responses, prolonged reactivity of the resident glia, along with the peripheral immune cells, create widespread toxicity to retinal ganglion cell (RGC) axons, somas, and synapses. As much as the synchronized responses of astrocytes and microglia to gla...
Source: Cell Research - August 4, 2021 Category: Cytology Authors: G ülgün Tezel Source Type: research

Video, ergo sum: The search for response to natural light
Cell Stem Cell. 2022 Mar 3;29(3):349-350. doi: 10.1016/j.stem.2022.02.005.ABSTRACTHow "real" can a stem cell-derived human organoid be? In this issue of Cell Stem Cell, Saha et al. demonstrate that cone photoreceptors in human stem cell-derived retinal organoids can respond to light not unlike foveal cones of adult primate.PMID:35245464 | DOI:10.1016/j.stem.2022.02.005
Source: Cell Stem Cell - March 4, 2022 Category: Stem Cells Authors: Juan Angueyra Wei Li Source Type: research

OCTA Biomarker Search in Patients with nAMD: Influence of Retinal Fluid on Time-Dependent Biomarker Response
CONCLUSIONS: OCTA-based parameters VA, TVL, TNJ, and MNVarea show a strong response to anti-VEGF therapy over time, independent of the presence of IRF, SRF or RT. We conclude that the above listed OCTA parameters could contribute to our understanding of MNV biology and to guide individualized treatment in the future.TRIAL REGISTRY: The authors confirm that all ongoing and related trials are registered. ClinicalTrials.gov Number: NCT02521142.PMID:36891909 | DOI:10.1080/02713683.2023.2184318
Source: Current Eye Research - March 9, 2023 Category: Opthalmology Authors: Reinhard Told Adrian Reumueller Markus Schranz Jonas Brugger G ünther Weigert Gregor Sebastian Reiter Stefan Sacu Ursula Schmidt-Erfurth Source Type: research