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Nutrition: Vitamin A

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Neuroprotective Effect of Tauroursodeoxycholic Acid (TUDCA) on In Vitro and In Vivo Models of Retinal Disorders: A Systematic Review
CONCLUSION: This systematic review demonstrated that TUDCA has neuroprotective effect on in vivo and in vitro models of retinal disorders, reinforcing the currently available evidence that TUDCA could be a promising therapeutic agent in retinal diseases treatment. However, well designed clinical trials are necessary to appraise the efficacy of TUDCA in clinical setting.PMID:37691227 | DOI:10.2174/1570159X21666230907152207
Source: Current Neuropharmacology - September 11, 2023 Category: Drugs & Pharmacology Authors: Jiaxian Li Ziyang Huang Yu Jin Lina Liang Yamin Li Kai Xu Wei Zhou Xiaoyu Li Source Type: research

Role of Vitamins in Cardiovascular Health: Know Your Facts-Part 2
Curr Vasc Pharmacol. 2023 Sep 11. doi: 10.2174/1570161121666230911115725. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a major cause of morbidity/mortality world-wide, hence preventive interventions are crucial. Observational data showing beneficial CV-effects of vitamin supplements, promoted by self-proclaimed experts, have led to ~50% of Americans using multivitamins; this practice has culminated into a multi-billion-dollar business. However, robust evidence is lacking, and certain vitamins might incur harm. This two-part review focuses on the attributes or concerns about specific vitamin consumption on ...
Source: Atherosclerosis - September 11, 2023 Category: Cardiology Authors: Antonis A Manolis Theodora A Manolis Helen Melita Antonis S Manolis Source Type: research

Reliability of gaze-contingent perimetry
Behav Res Methods. 2023 Sep 11. doi: 10.3758/s13428-023-02225-y. Online ahead of print.ABSTRACTStandard automated perimetry, a psychophysical task performed routinely in eyecare clinics, requires observers to maintain fixation for several minutes at a time in order to measure visual field sensitivity. Detection of visual field damage is confounded by eye movements, making the technique unreliable in poorly attentive individuals and those with pathologically unstable fixation, such as nystagmus. Microperimetry, which utilizes 'partial gaze-contingency' (PGC), aims to counteract eye movements but only corrects for gaze posit...
Source: Behavior Research Methods - September 11, 2023 Category: Psychiatry & Psychology Authors: Nikita Thomas Jennifer H Acton Jonathan T Erichsen Tony Redmond Matt J Dunn Source Type: research

Neuroprotective Effect of Tauroursodeoxycholic Acid (TUDCA) on In Vitro and In Vivo Models of Retinal Disorders: A Systematic Review
CONCLUSION: This systematic review demonstrated that TUDCA has neuroprotective effect on in vivo and in vitro models of retinal disorders, reinforcing the currently available evidence that TUDCA could be a promising therapeutic agent in retinal diseases treatment. However, well designed clinical trials are necessary to appraise the efficacy of TUDCA in clinical setting.PMID:37691227 | DOI:10.2174/1570159X21666230907152207
Source: Current Neuropharmacology - September 11, 2023 Category: Drugs & Pharmacology Authors: Jiaxian Li Ziyang Huang Yu Jin Lina Liang Yamin Li Kai Xu Wei Zhou Xiaoyu Li Source Type: research

Evaluation of Long-Term Nutrition Outcomes After Duodenal Switch: A Systematic Review and Meta-Analysis
CONCLUSIONS: Despite displaying comparable nutrition-related outcomes to mid-term follow-up, our study demonstrated that BPD-DS could result in a high level of long-term nutrition deficiency after BPD-DS for selected patients. However, further randomized controlled studies with standardized supplementation regimens and improvement in compliance are necessary to evaluate and prevent long-term nutritional deficiencies after BPD-DS.PMID:37694730 | DOI:10.1177/00031348231201886
Source: The American Surgeon - September 11, 2023 Category: Surgery Authors: Hayato Nakanishi Kamal Abi Mosleh Mohammad Al-Kordi Katie Marrero Mohammad Kermansaravi S Scott Davis Benjamin Clapp Omar M Ghanem Source Type: research

Reliability of gaze-contingent perimetry
Behav Res Methods. 2023 Sep 11. doi: 10.3758/s13428-023-02225-y. Online ahead of print.ABSTRACTStandard automated perimetry, a psychophysical task performed routinely in eyecare clinics, requires observers to maintain fixation for several minutes at a time in order to measure visual field sensitivity. Detection of visual field damage is confounded by eye movements, making the technique unreliable in poorly attentive individuals and those with pathologically unstable fixation, such as nystagmus. Microperimetry, which utilizes 'partial gaze-contingency' (PGC), aims to counteract eye movements but only corrects for gaze posit...
Source: Behavior Research Methods - September 11, 2023 Category: Psychiatry & Psychology Authors: Nikita Thomas Jennifer H Acton Jonathan T Erichsen Tony Redmond Matt J Dunn Source Type: research

Role of Vitamins in Cardiovascular Health: Know Your Facts-Part 2
Curr Vasc Pharmacol. 2023 Sep 11. doi: 10.2174/1570161121666230911115725. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a major cause of morbidity/mortality world-wide, hence preventive interventions are crucial. Observational data showing beneficial CV-effects of vitamin supplements, promoted by self-proclaimed experts, have led to ~50% of Americans using multivitamins; this practice has culminated into a multi-billion-dollar business. However, robust evidence is lacking, and certain vitamins might incur harm. This two-part review focuses on the attributes or concerns about specific vitamin consumption on ...
Source: Current Vascular Pharmacology - September 11, 2023 Category: Drugs & Pharmacology Authors: Antonis A Manolis Theodora A Manolis Helen Melita Antonis S Manolis Source Type: research

A Review on the Cytotoxicity and Antibacterial Effect of Marine Organisms of Persian Gulf
Adv Biomed Res. 2023 Jul 27;12:195. doi: 10.4103/abr.abr_290_22. eCollection 2023.ABSTRACTMarine organisms contain several natural products and bioactive compounds, including hydrolyzed proteins, antioxidant peptides, gelatin, collagen, ω-3 unsaturated fatty acids, vitamin A, vitamin D, calcium phosphate, hydroxyapatite, chitosan, lectin, and various toxins. They can inhibit diverse diseases, be used in pharmaceutical compounds, or as antibiotics and pigments. In this regard, these microorganisms are of crucial medicinal and economical importance. Thanks to new technologies and advanced laboratory methods, bioactive compo...
Source: Biomed Res - September 11, 2023 Category: Research Authors: Seyed Erfan Mousavi Sheyda Razaghi Nafiseh Emami Afsaneh Yegdaneh Source Type: research

The profile of adipokines associated with fibrosis and impaired microcirculation in systemic sclerosis
CONCLUSION: Adipsin may be considered a pivotal protein in the development of both fibrosis and impaired microcirculation. Its abnormal concentration reflects the intensity of skin thickening and the presence of pulmonary arterial hypertension. Adipsin, visfatin, and apelin are adipose tissue-derived molecules associated with digital vasculopathy.PMID:37696138 | DOI:10.1016/j.advms.2023.09.001
Source: Advances in Medical Sciences - September 11, 2023 Category: Biomedical Science Authors: Anna Niemczyk Anna Wa śkiel-Burnat Micha ł Zaremba Joanna Czuwara Lidia Rudnicka Source Type: research

Vitamin A biomarkers were associated with AGP and CRP over the course of a human norovirus challenge infection
Br J Nutr. 2023 Sep 11:1-19. doi: 10.1017/S0007114523002076. Online ahead of print.ABSTRACTRetinol binding protein (RBP) is used as a proxy for retinol in population-based assessments of vitamin A deficiency (VAD) for cost-effectiveness and feasibility. When the cutoff of <0.7 mol/L for retinol is applied to RBP to define VAD, an equivalence of the two biomarkers is assumed. Evidence suggests that the relationship between retinol and RBP is not 1:1, particularly in populations with a high burden of infection or inflammation. The goal of this analysis was to longitudinally evaluate the retinol:RBP ratio over one month of...
Source: The British Journal of Nutrition - September 11, 2023 Category: Nutrition Authors: Courtney P Victor Juan S Leon Anne M Williams Source Type: research

The profile of adipokines associated with fibrosis and impaired microcirculation in systemic sclerosis
CONCLUSION: Adipsin may be considered a pivotal protein in the development of both fibrosis and impaired microcirculation. Its abnormal concentration reflects the intensity of skin thickening and the presence of pulmonary arterial hypertension. Adipsin, visfatin, and apelin are adipose tissue-derived molecules associated with digital vasculopathy.PMID:37696138 | DOI:10.1016/j.advms.2023.09.001
Source: Advances in Medical Sciences - September 11, 2023 Category: Biomedical Science Authors: Anna Niemczyk Anna Wa śkiel-Burnat Micha ł Zaremba Joanna Czuwara Lidia Rudnicka Source Type: research

Novel retinal imaging biomarkers for cognitive decline: abridged secondary publication
Hong Kong Med J. 2023 Aug;29 Suppl 4(4):4-7.NO ABSTRACTPMID:37690798
Source: Hong Kong Med J - September 10, 2023 Category: General Medicine Authors: C Y Cheung V T T Chan L W C Au C C Tham T C Y Kowk C T V Mok Source Type: research

Effects of Progesterone and Other Gonadal Hormones on Glutamatergic Circuits in the Retina
CONCLUSIONS: Progesterone, but not estrogen or testosterone, activated glutamate release in the mouse retina. Increases in the concentration of progesterone during pregnancy did not induce any detectable change in retinal thickness.PMID:37690823 | DOI:10.1272/jnms.JNMS.2023_90-405
Source: Journal of Nippon Medical School - September 10, 2023 Category: Universities & Medical Training Authors: Mahito Ohkuma Takuma Maruyama Toshiyuki Ishii Nozomi Igarashi Keiko Azuma Tatsuya Inoue Ryo Obata Ei-Ichi Miyachi Makoto Kaneda Source Type: research

Novel retinal imaging biomarkers for cognitive decline: abridged secondary publication
Hong Kong Med J. 2023 Aug;29 Suppl 4(4):4-7.NO ABSTRACTPMID:37690798
Source: Hong Kong Med J - September 10, 2023 Category: General Medicine Authors: C Y Cheung V T T Chan L W C Au C C Tham T C Y Kowk C T V Mok Source Type: research