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Health Information Networks: Learning from One Another. 2nd IFHRO SEAR Conference, Perth, Western Australia, 13 October 2009.
Authors: Gamage S PMID: 28683617 [PubMed]
Source: Health Information Management Journal - July 9, 2017 Category: Health Management Tags: HIM J Source Type: research

Perioperative Betablockade: A Conundrum Still in Need of Study!
PMID: 29762224 [PubMed - in process]
Source: Anesthesia and Analgesia - May 17, 2018 Category: Anesthesiology Authors: Foëx P, Sear JW Tags: Anesth Analg Source Type: research

Formation of Unexpectedly Active Ni-Fe Oxygen Evolution Electrocatalysts by Physically Mixing Ni and Fe Oxyhydroxides
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Mikaela Gorlin, Petko Chernev, Paul Paciok, Cheuk-Wai Tai, Jorge Ferreira de Araujo, Tobias Reier, Marc Heggen, R Dunin-Borkowski, Peter Strasser, Holger Dau We present an unusual, yet facile, strategy towards formation of physically mixed Ni-Fe(OxHy) oxygen evolution electrocatalysts. We use in situ X-ray absorption and UV-vis spectroscopy, and high-resolution imaging to demonstrate... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - December 12, 2018 Category: Chemistry Authors: Mikaela Gorlin Source Type: research

A review on possible mechanisms of sonocrystallisation in solution.
Abstract Sonocrystallisation is the application of ultrasound to the crystallisation process. The benefits obtained by sonication have been widely studied since the beginning of the 20th century and so far it is clear that ultrasound can be a very useful tool for enhancing crystallisation and controlling the properties of the final product. Crystal size, polymorphs, purity, process repeatability and lower induction time are only some of the advantages of sonocrystallisation. Even though the effects of sonication on crystallisation are quite clear, the physical explanation of the phenomena involved is still lacking...
Source: Ultrasonics Sonochemistry - June 20, 2019 Category: Chemistry Authors: Nalesso S, Bussemaker MJ, Sear RP, Hodnett M, Lee J Tags: Ultrason Sonochem Source Type: research

A Fast and Memory ‐Efficient Spectral Library Search Algorithm using Locality‐Sensitive Hashing
This article is protected by copyright. All rights reserved
Source: Proteomics - May 15, 2020 Category: Biochemistry Authors: Lei Wang, Kaiyuan Liu, Sujun Li, Haixu Tang Tags: Research Article Source Type: research

Correction for Sear et al., Human settlement of East Polynesia earlier, incremental, and coincident with prolonged South Pacific drought Correction
ENVIRONMENTAL SCIENCES Correction for “Human settlement of East Polynesia earlier, incremental, and coincident with prolonged South Pacific drought,” by David A. Sear, Melinda S. Allen, Jonathan D. Hassall, Ashley E. Maloney, Peter G. Langdon, Alex E. Morrison, Andrew C. G. Henderson, Helen Mackay, Ian W. Croudace, Charlotte Clarke, Julian P....
Source: Proceedings of the National Academy of Sciences - June 15, 2020 Category: Science Tags: Corrections Source Type: research

Structure-activity relationship study of cytotoxic neolignan derivatives using multivariate analysis and computation-aided drug design.
Abstract Dehydrodieugenol B and five related natural neolignans were isolated from the Brazilian plant species Nectandra leucantha. Three of these compounds were shown to be active against murine (B16F10) and human (A2058) melanoma cells but non-toxic to human fibroblasts (T75). These results stimulated the preparation of a series of 23 semi-synthetic derivatives in order to explore structure-activity relationships and study the biological potential of these derivatives against B16F10 and A2058 cell lines. These structurally-related neolignan derivatives were analyzed by multivariate statistics and machine learnin...
Source: Bioorganic and Medicinal Chemistry Letters - July 8, 2020 Category: Chemistry Authors: de Sousa FS, Baldim JL, Azevedo RA, Figueiredo CR, Pieper P, Sear CE, Anderson EA, Lago JHG Tags: Bioorg Med Chem Lett Source Type: research

A Fast and Memory ‐Efficient Spectral Library Search Algorithm Using Locality‐Sensitive Hashing
AbstractWith the accumulation of MS/MS spectra collected in spectral libraries, the spectral library searching approach emerges as an important approach for peptide identification in proteomics, complementary to the commonly used protein database searching approach, in particular for the proteomic analyses of well ‐studied model organisms, such as human. Existing spectral library searching algorithms compare a query MS/MS spectrum with each spectrum in the library with matched precursor mass and charge state, which may become computationally intensive with the rapidly growing library size. Here, the softwar e msSLASH, wh...
Source: Proteomics - June 28, 2020 Category: Biochemistry Authors: Lei Wang, Kaiyuan Liu, Sujun Li, Haixu Tang Tags: Research Article Source Type: research

Hypertension: A Changing Role for Anesthesiologists.
PMID: 33079861 [PubMed - in process]
Source: Anesthesia and Analgesia - October 22, 2020 Category: Anesthesiology Authors: Foëx P, Sear JW Tags: Anesth Analg Source Type: research

A synonymous variant in a non-canonical exon of CDC45 disrupts splicing in two affected sibs with Meier-Gorlin syndrome with craniosynostosis
This report adds to the initial patient cohort in which several synonymous variants were also described, further highlighting the contribution of this variant type in CDC45. It also reiterates the true potential pathogenicity of synonymous variants, which is a mutation type that is commonly ignored in variant prioritization strategies.PMID:33639314 | DOI:10.1016/j.ejmg.2021.104182
Source: European Journal of Medical Genetics - February 27, 2021 Category: Genetics & Stem Cells Authors: Karen M Knapp Bridget Fellows Shagun Aggarwal Ashwin Dalal Louise S Bicknell Source Type: research

SUFU-associated Gorlin syndrome: Expanding the spectrum between classic nevoid basal cell carcinoma syndrome and multiple hereditary infundibulocystic basal cell carcinoma
We present two patients with MHIBCC, along with a more complex cutaneous and extracutaneous phenotype. MHIBCC syndrome and BCNS may share clinical features and, indeed, both syndromes probably represent different degrees of upregulation in the Hh pathway.PMID:36825822 | DOI:10.1111/ajd.14014
Source: The Australasian Journal of Dermatology - February 24, 2023 Category: Dermatology Authors: Marcial Álvarez-Salafranca Mar Garc ía-García Andrea Montes-Torres Ignacio Rivera-Fuertes Mar ía Teresa López-Giménez Mariano Ara Source Type: research