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Therapy: Corticosteroid Therapy

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Total 18766 results found since Jan 2013.

Health economic analyses of psoriasis management: a systematic literature search
The objective was to identify health economic evaluations of psoriasis treatments that have been published to date. Of particular interest were the mostly used analysis and outcome parameters, the compared treatments, and the question, if available health economic studies may be used to perform a meta-analysis of qualitative findings. A systematic literature search using PubMed Medline, Ovid Medline, and Cochrane Library was performed for articles, published and available until mid of January 2016. Among the key words were the terms “psoriasis” and “cost-effectiveness”. The search resulted in 318 articles without d...
Source: Archives of Dermatological Research - July 18, 2016 Category: Dermatology Source Type: research

Do animal models of brain tumors replicate human peritumoral edema? a systematic literature search
ConclusionNo animal model currently exists that enable the investigation of novel candidates for the treatment of peritumoral brain edema. With current interest in alternative treatments for peritumoral brain edema, there is an unmet need for clinically relevant animal models.
Source: Journal of Neuro-Oncology - February 9, 2023 Category: Cancer & Oncology Source Type: research

What Is the Right Dose of Systemic Corticosteroids for Intensive Care Unit Patients with Chronic Obstructive Pulmonary Disease Exacerbations?. A Question in Search of a Definitive Answer.
PMID: 24787061 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - May 1, 2014 Category: Respiratory Medicine Authors: Abroug F, Krishnan JA Tags: Am J Respir Crit Care Med Source Type: research

Glenohumeral Corticosteroid Injections in Adhesive Capsulitis: A Systematic Search and Review
To assess the literature on outcomes of corticosteroid injections for adhesive capsulitis, and, in particular, image-guided corticosteroid injections.
Source: PM and R - July 1, 2014 Category: Rehabilitation Authors: Amos Song, Laurence D. Higgins, Joel Newman, Nitin B. Jain Tags: Analytical Review: Systematic Search Source Type: research

Analysis of patient-reported symptoms with respect to TCS usage: A self-identified cohort of patients with RSS/TSA/TSW
Background: Topical corticosteroids (TCS) have been the mainstay of treatment for inflammatory dermatoses and are felt to be safe when used appropriately. In response to increased reports about red skin syndrome (RSS) and topical steroid addiction/withdrawal (TSA/TSW), a systematic review (2015) conducted by the National Eczema Association concluded that RSS/TSA/TSW is a potential adverse effect of prolonged use of topical steroids. The phenomenon of RSS/TSA/TSW has been deemed rare. There is no validated definition, no patient registry, and no evidence-based treatment.
Source: Journal of the American Academy of Dermatology - May 31, 2017 Category: Dermatology Source Type: research

New-onset lupus nephritis after male-to-female sex reassignment surgery.
We report an original case of a 27-year-old transgender woman who developed lupus nephritis after male-to-female sex reassignment surgery. The patient had been taking hormones to induce feminization since the age of 18. She was admitted with malar "butterfly" rash, anasarca and hypertension, associated with an increase in serum creatinine (1.7 mg/dl). Renal involvement was characterized by nephritic and nephrotic syndrome. Autoantibody tests were positive for antinuclear antibodies and anti-double-stranded DNA, and complement levels were markedly reduced. Renal biopsy demonstrated diffuse proliferative glomerulonephritis...
Source: Lupus - September 19, 2018 Category: Rheumatology Authors: Pontes LT, Camilo DT, De Bortoli MR, Santos RSS, Luchi WM Tags: Lupus Source Type: research

Vemurafenib Treatment of Pleomorphic Xanthoastrocytoma in a Child With Down Syndrome
In conclusion, we have shown the safety and efficacy of Vemurafenib in a pediatric patient with DS affected by PXA. Ethics Statement This study was carried out in accordance with the recommendations of the Internal Review Board of the Bambino Gesù Children's Hospital with written informed consent from all subjects. All subjects gave written informed consent in accordance with the Declaration of Helsinki. The protocol was approved by the Internal Review Board of the Bambino Gesù Children's Hospital. Informed Consent The authors declare that written informed consent was obtained from the p...
Source: Frontiers in Oncology - April 11, 2019 Category: Cancer & Oncology Source Type: research

Systemic corticosteroids for radicular and non-radicular low back pain
CONCLUSIONS: Systemic corticosteroids appear to be slightly effective at improving short-term pain and function in people with radicular low back pain not due to spinal stenosis, and might slightly improve long-term function. The effects of systemic corticosteroids in people with non-radicular low back pain are unclear and systemic corticosteroids are probably ineffective for spinal stenosis. A single dose or short course of systemic corticosteroids for low back pain does not appear to cause serious harms, but evidence is limited.PMID:36269125 | PMC:PMC9585990 | DOI:10.1002/14651858.CD012450.pub2
Source: Cochrane Database of Systematic Reviews - October 21, 2022 Category: General Medicine Authors: Roger Chou Rafael Zambelli Pinto Rongwei Fu Robert A Lowe Nicholas Henschke James H McAuley Tracy Dana Source Type: research

Interventions for preventing and treating kidney disease in IgA vasculitis
CONCLUSIONS: There are no substantial changes in conclusions from this update compared with the initial review or the previous update despite the addition of five studies. From generally low to moderate certainty evidence, we found that there may be little or no benefit in the use of corticosteroids or antiplatelet agents to prevent persistent kidney disease in children with IgAV in participants with no or minimal kidney involvement at presentation. We did not find any studies which evaluated corticosteroids in children presenting with IgAV and nephritic and/or nephrotic syndrome, although corticosteroids are recommended i...
Source: Cochrane Database of Systematic Reviews - February 28, 2023 Category: General Medicine Authors: Deirdre Hahn Elisabeth M Hodson Jonathan C Craig Source Type: research

Inhaled corticosteroids versus placebo   for stable chronic obstructive pulmonary disease
CONCLUSIONS: This systematic review updates the evidence base for ICS monotherapy with newly published trials to aid the ongoing assessment of their role for people with COPD. Use of ICS alone for COPD likely results in a reduction of exacerbation rates of clinical relevance, probably results in a reduction in the rate of decline of FEV1 of uncertain clinical relevance and likely results in a small improvement in health-related quality of life not meeting the threshold for a minimally clinically important difference. These potential benefits should be weighed up against adverse events (likely to increase local oropharyngea...
Source: Cochrane Database of Systematic Reviews - March 27, 2023 Category: General Medicine Authors: Ian A Yang Olivia R Ferry Melissa S Clarke Esther Ha Sim Kwun M Fong Source Type: research

Long-acting muscarinic antagonist (LAMA) plus long-acting beta-agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive pulmonary disease
CONCLUSIONS: Combination LAMA+LABA therapy probably holds similar benefits to LABA+ICS for exacerbations and quality of life, as measured by the St George's Respiratory Questionnaire, for people with moderate to severe COPD, but offers a larger improvement in FEV1 and a slightly lower risk of pneumonia. There is little to no difference between LAMA+LABA and LAMA+ICS in the odds of having a serious adverse event. Whilst all-cause death may be lower with LABA+ICS, there was a very small number of events in the analysis, translating to a low absolute risk. Findings are based on moderate- to high-certainty evidence from hetero...
Source: Cochrane Database of Systematic Reviews - June 5, 2023 Category: General Medicine Authors: Nobuhiko Fukuda Nobuyuki Horita Ayami Kaneko Atsushi Goto Takeshi Kaneko Erika Ota Kayleigh M Kew Source Type: research

Red flags to screen for vertebral fracture in people presenting with low back pain
CONCLUSIONS: The available evidence suggests that only a few red flags are potentially useful in guiding clinical decisions to further investigate people suspected to have a vertebral fracture. Most red flags were not useful as screening tools to identify vertebral fracture in people with low back pain. In primary care, 'older age' was informative for 'unspecified vertebral fracture', and 'trauma' and 'corticosteroid use' were both informative for 'unspecified vertebral fracture' and 'osteoporotic vertebral fracture'. In secondary care, 'older age' was informative for 'osteoporotic vertebral fracture' and 'trauma' was info...
Source: Cochrane Database of Systematic Reviews - August 24, 2023 Category: General Medicine Authors: Christopher S Han Mark J Hancock Aron Downie Jeffrey G Jarvik Bart W Koes Gustavo C Machado Arianne P Verhagen Christopher M Williams Qiuzhe Chen Christopher G Maher Source Type: research