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Total 43642 results found since Jan 2013.
Brain tissue properties link cardio-vascular risk factors, mood and cognitive performance in the CoLaus|PsyCoLaus epidemiological cohort
Neurobiol Aging. 2021 Feb 16;102:50-63. doi: 10.1016/j.neurobiolaging.2021.02.002. Online ahead of print.ABSTRACTGiven the controversy about the impact of modifiable risk factors on mood and cognition in ageing, we sought to investigate the associations between cardio-vascular risk, mental health, cognitive performance and brain anatomy in mid- to old age. We analyzed a set of risk factors together with multi-parameter magnetic resonance imaging (MRI) in the CoLaus|PsyCoLaus cohort (n > 1200). Cardio-vascular risk was associated with differences in brain tissue properties - myelin, free tissue water, iron content - and ...
Source: Neurobiology of Aging - March 25, 2021 Category: Geriatrics Authors: Olga Trofimova Leyla Loued-Khenissi Giulia DiDomenicantonio Antoine Lutti Matthias Kliegel Silvia Stringhini Pedro Marques-Vidal Peter Vollenweider G érard Waeber Martin Preisig Ferath Kherif Bogdan Draganski Source Type: research
Layers of interstitial fluid flow along a "slit-shaped" vascular adventitia
J Zhejiang Univ Sci B. 2021 Aug 15;22(8):647-663. doi: 10.1631/jzus.B2000590.ABSTRACTInterstitial fluid (ISF) flow through vascular adventitia has been discovered recently. However, its kinetic pattern was unclear. We used histological and topographical identification to observe ISF flow along venous vessels in rabbits. By magnetic resonance imaging (MRI) in live subjects, the inherent pathways of ISF flow from the ankle dermis through the legs, abdomen, and thorax were enhanced by paramagnetic contrast. By fluorescence stereomicroscopy and layer-by-layer dissection after the rabbits were sacrificed, the perivascular and a...
Source: J Zhejiang Univ Sci ... - August 20, 2021 Category: Science Authors: Hongyi Li You Lyu Xiaoliang Chen Bei Li Qi Hua Fusui Ji Yajun Yin Hua Li Source Type: research
The dependencies of fronto‐parietal BOLD responses evoked by covert visual search suggest eye‐centred coding
Abstract
Visual scenes explored covertly are initially represented in a retinal frame of reference (FOR). On the other hand, ‘later’ stages of the cortical network allocating spatial attention most probably use non‐retinal or non‐eye‐centred representations as they may ease the integration of different sensory modalities for the formation of supramodal representations of space. We tested if the cortical areas involved in shifting covert attention are based on eye‐centred or non‐eye‐centred coding by using functional magnetic resonance imaging. Subjects were scanned while detecting a target item (a regularly...
Source: European Journal of Neuroscience - February 13, 2013 Category: Neuroscience Authors: A. Atabaki, P.W. Dicke, H.‐O. Karnath, P. Thier Tags: Research Report Source Type: research
Magnetic Resonance Imaging is More Sensitive than Computed Tomography Angiography for the Detection of Endoleaks after Endovascular Abdominal Aortic Aneurysm Repair: A Systematic Review
Conclusions: MRI is more sensitive compared to CTA for the detection of post-EVAR endoleaks, especially for the detection of type II endoleaks. MRI should be considered in patients with continued AAA growth and negative or uncertain findings at CTA.
Source: European Journal of Vascular and Endovascular Surgery - February 11, 2013 Category: Surgery Authors: J. Habets, H.J.A. Zandvoort, J.B. Reitsma, L.W. Bartels, F.L. Moll, T. Leiner, J.A. van Herwaarden Tags: Aneurysms Source Type: research
In search of signaling pathways critical for ovarian graft reception: Akt1 is essential for long-term survival of ovarian grafts
Conclusion(s): Akt1 is essential for ovarian graft reception. However, surprisingly the impact of Akt1 deficiency was most profound not in the early stages of angiogenesis but rather in long-term survival of the graft.
Source: Fertility and Sterility - November 4, 2013 Category: Reproduction Medicine Authors: Yoni Cohen, Hagit Dafni, Reut Avni, Tal Raz, Inbal Biton, Brian Hemmings, Michal Neeman Tags: Reproductive science Source Type: research
Carotid Plaque MRI and Stroke Risk: A Systematic Review and Meta-analysis
Dedicated magnetic resonance imaging (MRI) of plaque composition offers stroke risk information beyond measurement of luminal stenosis in carotid atherosclerotic disease. Stenosis severity is widely used as a marker for stroke risk in patients with atherosclerotic carotid disease. However, evidence also suggests plaque composition can also predict stroke risk independent of stenosis severity (den Hartog AG et al, Eur J Vasc Endovasc Surg 2013;45:7-21). MRI measurements of plaque composition may help characterize carotid plaques with respect to stroke risk. However, individual studies have been relatively small, and it is ...
Source: Journal of Vascular Surgery - March 24, 2014 Category: Surgery Authors: A. Gupta, H. Baradaran, A.D. Schweitzer Tags: Abstracts Source Type: research
Abstract A10: Unsupervised deconvolution of dynamic imaging reveals intratumor vascular heterogeneity and repopulation dynamics
Intratumor functional heterogeneity is the presence of multiple subpopulations or localized regions with different physiological properties that affect cancer biology (e.g., motility, invasion) and/or response to systemic therapy. Functional heterogeneity may reflect unique aspects of the tumor microenvironment or cellular genetic diversity including, but not limited to, the consequences of different localized patterns of vascular perfusion, stromal infiltration, somatic mutation, epigenetic modifications. Given the continuing improvements in tumor imaging technologies and the biological importance of tumor vascularization...
Source: Cancer Research - January 12, 2015 Category: Cancer & Oncology Authors: Chen, L., Choyke, p., Clarke, R., Bhujwalla, Z., Wang, Y. Tags: Tumor-Associated Blood Vessels and Lymphatics Source Type: research
More of Brain Aging Than Thought May Be Vascular in Nature
Age-related deterioration in blood vessels and the broader cardiovascular system generates damage in the brain. Blood vessel walls are elastic, a property that depends on the molecular structure of the proteins making up the extracellular matrix in that tissue. This structure is progressively degraded by the presence of sugary metabolic waste known as advanced glycation end-products (AGEs), which leads to the formation of cross-links between proteins and a consequent loss of elasticity. Stiffening of blood vessels causes hypertension and many of the cellular and molecular mechanisms involved overlap with those that speed t...
Source: Fight Aging! - March 5, 2015 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
