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Vaccination: Pneomococcal Vaccine

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Total 3078 results found since Jan 2013.

Knowledge gaps on paediatric respiratory infections in Morocco, Northern Africa
Conclusions Further efforts should be made towards the development of adequate surveillance programs to better clarify the epidemiology, etiology, antimicrobial susceptibility patterns and the effectiveness of the preventives and curatives strategies in place against paediatric ARIs in Morocco. Additionally, a holistical approach should be used to identify the heath determinants of ARIs among children.
Source: Archives of Public Health - June 15, 2015 Category: Global & Universal Source Type: research

New Paradigms in Sepsis: From Prevention to Protection of Failing Microcirculation
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - July 1, 2015 Category: Hematology Authors: J. Hawiger, R. A Veach, J. Zienkiewicz Tags: Review Article Source Type: research

New Paradigms in Sepsis: From Prevention to Protection of Failing Microcirculation.
This article is protected by copyright. All rights reserved. PMID: 26190521 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - July 18, 2015 Category: Hematology Authors: Hawiger J, Veach RA, Zienkiewicz J Tags: J Thromb Haemost Source Type: research

Association between pneumococcal vaccination and cardiovascular outcomes: a systematic review and meta-analysis of cohort studies
Conclusion PV is associated with decreased risk of cardiovascular events and mortality. This protective effect increases at older age and in high cardiovascular risk subjects and decreases as the time elapses from PV. PV decreases the risk of MI and cerebrovascular events in the elderly.
Source: European Journal of Preventive Cardiology - August 10, 2015 Category: Cardiology Authors: Vlachopoulos, C. V., Terentes-Printzios, D. G., Aznaouridis, K. A., Pietri, P. G., Stefanadis, C. I. Tags: Original scientific paper Source Type: research

Health Economic Impact of 13-Valent Pneumococcal Conjugate Vaccine In Finnish Home Care Customers ≥50 Years With Underlying Chronic Medical Conditions
Hospital-treated pneumonias (HTP) are associated with substantial individual and societal burden in adults (≥50 years) and elderly. Moreover, adults e.g. with vascular, metabolic or respiratory diseases have a 3-6 times higher risk of HTP when compared with their healthy controls. Persons at risk are likely to benefit most from pneumococcal vaccinations. The 13-valent pneumococcal conjugate vaccine (PCV13) has showed to prevent community-acquired pneumonia and invasive pneumococcal disease in adults.
Source: Value in Health - October 23, 2015 Category: Global & Universal Authors: PT Mankinen, EJ Soini, J Laine, M Linna, H Åhman, J Martikainen Tags: INFECTION – Cost Studies Source Type: research

Reccurrent invasive pneumococcal disease in children host factors and vaccination response.
Authors: Ingels HA Abstract Streptococcus pneumoniae is still a leading cause of septicaemia, pneumonia and meningitis in young children world-wide with over half a million children dying annually from pneumococcal disease.  Some children are prone to repeated episodes of invasive pneumococcal disease (IPD) because of an underlying predisposing disease. Recurrent IPD (rIPD) is a rarity and published reports on rIPD are limited by having few children included, selected groups of patients or short follow-up periods. Deficiencies in the innate or adaptive immune system have been described in children with rIPD, but t...
Source: Danish Medical Journal - December 12, 2015 Category: Journals (General) Tags: Dan Med J Source Type: research

Global Burden of Neonatal Invasive Pneumococcal Disease: A Systematic Review and Meta-analysis
Conclusions: Pneumococcus was a recognized pathogen among neonates in all development regions of the world. The burden of neonatal IPD, particularly in the least-developed UN country stratum, requires substantial further evaluation.
Source: The Pediatric Infectious Disease Journal - January 12, 2016 Category: Infectious Diseases Tags: Original Studies Source Type: research

Methods and challenges for the health impact assessment of vaccination programs in Latin America
CONCLUSIONS Over the last years, a significant number of health impact assessments of pneumococcal and rotavirus vaccination programs have been conducted in Latin America and the Caribbean. These studies were carried out few years after the programs were implemented, meet the basic methodological requirements and suggest positive health impact. Future assessments should consider methodological issues and challenges arisen in these first studies conducted in the region. RESUMO OBJETIVO Descrever métodos e desafios enfrentados na avaliação do impacto de programas de vacinação, com foco nas vacinas pneumocócica conjugad...
Source: Revista de Saude Publica - January 15, 2016 Category: Global & Universal Source Type: research

Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice.
Abstract Streptococcus pneumoniae (S. pneumoniae) is a major pathogen worldwide. The currently available polysaccharide-based vaccines significantly reduce morbidity and mortality. However, the inherent disadvantages of the currently available polysaccharide-based vaccines have motivated the search for other bacterial immunogens capable of eliciting a protective immune response against S. pneumoniae. Fructose-1,6-bisphosphate aldolase (FBA) is a glycolytic enzyme, which was found to localize to the bacterial surface, where it functions as an adhesin. Previously, immunizing mice with recombinant FBA (rFBA) in...
Source: International Journal of Molecular Medicine - March 1, 2016 Category: Molecular Biology Authors: Elhaik Goldman S, Dotan S, Talias A, Lilo A, Azriel S, Malka I, Portnoi M, Ohayon A, Kafka D, Ellis R, Elkabets M, Porgador A, Levin D, Azhari R, Swiatlo E, Ling E, Feldman G, Tal M, Dagan R, Mizrachi Nebenzahl Y Tags: Int J Mol Med Source Type: research

Injection Site Lichenoid Dermatitis Following Pneumococcal Vaccination: Report and Review of Cutaneous Conditions Occurring at Vaccination Sites
Conclusions Dermatoses at the injection sites of vaccines can be granulomatous, immunity-related conditions, infections, lichenoid, neutrophilic, or pseudolymphomatous. Basal cell carcinoma and squamous cell carcinoma are the most common vaccination site-associated malignancies; however, melanoma and sarcomas (dermatofibrosarcoma protuberans, fibrosarcoma, and malignant fibrous histiocytoma) are also smallpox vaccine-related site neoplasms. A cutaneous immunocompromised district that is created by vaccine-induced local immunologic changes is hypothesized to be the pathogenesis of vaccination site reactions.
Source: Dermatology and Therapy - March 16, 2016 Category: Dermatology Source Type: research

Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions.
CONCLUSIONS: Our review findings have not identified conclusive evidence of benefit of HCW vaccination programmes on specific outcomes of laboratory-proven influenza, its complications (lower respiratory tract infection, hospitalisation or death due to lower respiratory tract illness), or all cause mortality in people over the age of 60 who live in care institutions. This review did not find information on co-interventions with healthcare worker vaccination: hand-washing, face masks, early detection of laboratory-proven influenza, quarantine, avoiding admissions, antivirals and asking healthcare workers with influenza or i...
Source: Cochrane Database of Systematic Reviews - June 1, 2016 Category: Journals (General) Authors: Thomas RE, Jefferson T, Lasserson TJ Tags: Cochrane Database Syst Rev Source Type: research

Common variable immunodeficiency, immune thrombocytopenia, rituximab and splenectomy: important considerations.
We present the case of a 44-year-old postpartum female who presented with nausea, vomiting and abdominal distension. Four years prior, she was hospitalized for treatment of immune thrombocytopenia (ITP) with splenectomy and rituximab followed by two episodes of bacterial meningitis despite immunizations. The recurrent meningitis had been attributed to splenectomy and immunotherapy. During this hospitalization, extensive workup for gastrointestinal pathology was negative and she was diagnosed with intestinal pseudo-obstruction. Her hospital course was complicated by development of severe pseudomonas pneumonia, and subsequen...
Source: Postgraduate Medicine - June 9, 2016 Category: Internal Medicine Tags: Postgrad Med Source Type: research

Japanese Government Continues to Ban the MMR Vaccine
Conclusion Japanese officials have made decisions that value the health and safety of their citizens when they have removed vaccines with dangerous side effects from their national vaccination program. Japan boasts a low infant mortality rate, despite — or perhaps because of  — mandating only a fraction of the vaccines required by other developed countries, including the United States. If you wish to learn more about the harmful ingredients in vaccines or the potential adverse reactions, we have compiled an easy-to-navigate list of vaccine package inserts from the manufacturers that you can view or download he...
Source: vactruth.com - June 23, 2016 Category: Allergy & Immunology Authors: Missy Fluegge Tags: Logical Missy Fluegge Top Stories HPV Vaccine MMR vaccine truth about vaccines Vaccine Death Source Type: blogs

Update on Human Rhinovirus and Coronavirus Infections
Semin Respir Crit Care Med 2016; 37: 555-571 DOI: 10.1055/s-0036-1584797Human rhinovirus (HRV) and coronavirus (HCoV) infections are associated with both upper respiratory tract illness (“the common cold”) and lower respiratory tract illness (pneumonia). New species of HRVs and HCoVs have been diagnosed in the past decade. More sensitive diagnostic tests such as reverse transcription-polymerase chain reaction have expanded our understanding of the role these viruses play in both immunocompetent and immunosuppressed hosts. Recent identification of severe acute respiratory syndrome and Middle East respiratory syndrome vi...
Source: Seminars in Respiratory and Critical Care Medicine - August 2, 2016 Category: Respiratory Medicine Authors: Greenberg, Stephen B. Tags: Review Article Source Type: research

Why pneumococci affect primarily humans
(Karolinska Institutet) A special variant of a sugar molecule in the human nose might explain why pneumococcal infections are more common in humans than in other animals, researchers from Karolinska Institutet in Sweden report in a study published in the journal Cell Host& Microbe. The discovery can help in the search for a broader vaccine able to protect against all types of pneumococci.
Source: EurekAlert! - Infectious and Emerging Diseases - September 1, 2016 Category: Infectious Diseases Source Type: news