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Vaccination: Influenza Vaccine
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Total 6581 results found since Jan 2013.
Eliminating Potential Effects of Other Infections during Selection of Nonhuman Primates for COVID-19 Research
Comp Med. 2023 Jan 4. doi: 10.30802/AALAS-CM-21-000086. Online ahead of print.ABSTRACTThe study of nonhuman primates (NHP) can provide significant insights into our understanding numerous infectious agents. The etiological agent of COVID-19, SARS-CoV-2 virus, first emerged in 2019 and has so far been responsible for the deaths of over 4 million people globally. In the frenzied search to understand its pathogenesis and immunology and to find measures for prevention and control of this pandemic disease, NHP, particularly macaques, are the preferred model because they manifest similar clinical signs and immunologic features a...
Source: Comparative Medicine - February 6, 2023 Category: Zoology Authors: M árcia Cr Andrade B árbara Rp Lemos Larissa M Silva Jerilyn K Pecotte Source Type: research
High Clinical Burden of Influenza Disease in Adults Aged ≥ 65 Years: Can We Do Better? A Systematic Literature Review
ConclusionsInfluenza exerts a considerable burden on adults aged ≥ 65 years and healthcare systems, with high incidence of hospitalization and mortality. Substantial influenza-associated clinical burden persists despite increasing vaccination coverage among adults aged ≥ 65 years across regions included in this review, which suggests limited effectivene ss of currently available seasonal influenza vaccines. To reduce influenza-associated clinical burden, influenza vaccine effectiveness must be improved. Next generation vaccine production using mRNA technology has demonstrated high effectiveness against another re...
Source: Advances in Therapy - February 15, 2023 Category: Drugs & Pharmacology Source Type: research
Eliminating Potential Effects of Other Infections during Selection of Nonhuman Primates for COVID-19 Research
Comp Med. 2023 Jan 4. doi: 10.30802/AALAS-CM-21-000086. Online ahead of print.ABSTRACTThe study of nonhuman primates (NHP) can provide significant insights into our understanding numerous infectious agents. The etiological agent of COVID-19, SARS-CoV-2 virus, first emerged in 2019 and has so far been responsible for the deaths of over 4 million people globally. In the frenzied search to understand its pathogenesis and immunology and to find measures for prevention and control of this pandemic disease, NHP, particularly macaques, are the preferred model because they manifest similar clinical signs and immunologic features a...
Source: Comparative Medicine - February 6, 2023 Category: Zoology Authors: M árcia Cr Andrade B árbara Rp Lemos Larissa M Silva Jerilyn K Pecotte Source Type: research
Pili Subunit PilA Contributes to the Cytoadhesion of < em > Glaesserella Parasuis < /em > to Host Cells and Provides Immunoprotection
In this study, the PilA protein, which is a common virulence factor in other bacteria that mediates adherence to the host, was assessed. The results suggested that the PilA protein of G. parasuis can mediate adhesion to host cells through FN and LN, which provides a new idea for the study of the pathogenicity of G. parasuis. Furthermore, fimbriae usually have high immunogenicity. Immunogenicity and protective capacity results showed that the use of this recombinant PilA antigen might be a promising candidate vaccine antigen with which to prevent G. parasuis infections.PMID:36920203 | DOI:10.1128/aem.02002-22
Source: Applied and Environmental Microbiology - March 15, 2023 Category: Microbiology Authors: Jiahui An Jinshuang Cai Baoge Zhang Yufeng Li Source Type: research
Dispute simmers over who first shared SARS-CoV-2 ’s genome
When GISAID, the widely used database for influenza and SARS-CoV-2 genomes,
issued a statement
last week about a set of controversial sequences from the Huanan Seafood Wholesale Market in Wuhan, China, the release explained by way of background that the repository was “an essential contributor to global health” trusted by thousands of data contributors from 215 nations and territories. But GISAID also included a claim that has been puzzling and infuriating some virologists for 3 years: It was the place where the first SARS-CoV-2 genomes were publicly shared, on 10 January 2020.
That claim challenges contempo...
Source: Science of Aging Knowledge Environment - March 29, 2023 Category: Geriatrics Source Type: research
Exclusion of older adults and immunocompromised individuals in influenza, pneumococcal and COVID-19 vaccine trials before and after the COVID-19 pandemic
CONCLUSIONS: During the COVID-19 pandemic, we found a decrease in the exclusion of older adults from vaccine trials but no significant change in the inclusion of immunocompromised individulas.PMID:37027085 | DOI:10.1007/s40520-023-02380-4
Source: Aging Clinical and Experimental Research - April 7, 2023 Category: Geriatrics Authors: Katrine Bukan Toby Pearce-Slade Mads Eiberg Marco Tinelli Dafna Yahav Jose Tuells Olivier Epaulard Jon G Holler Casper Roed Christian S øborg Jens-Ulrik St æhr Jensen Zitta Barrella Harboe Source Type: research
