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Factors Associated With African American Mothers' Perceptions of Human Papillomavirus Vaccination of Their Daughters: An Integrated Literature Review
Oncol Nurs Forum. 2021 Jul 1;48(4):371-389. doi: 10.1188/21.ONF.371-389.ABSTRACTPROBLEM IDENTIFICATION: African American (AA) women have a higher mortality rate for cervical and other cancers and are less likely to have received the human papillomavirus (HPV) vaccine than White women. Mothers play a significant family role and have a unique relationship with their daughters. Mothers' positive views on HPV vaccination may enhance the HPV vaccination rate among their daughters.LITERATURE SEARCH: The review was conducted by searching literature in PubMed®, CINAHL®, ScienceDirect, Ovid MEDLINE®, and ProQuest databases. The ...
Source: Oncology Nursing Forum - June 18, 2021 Category: Nursing Authors: Stella Dike Wyona M Freysteinson Source Type: research

Proteogenomic analysis unveils the HLA Class I-presented immunopeptidome in melanoma and EGFR-mutant lung adenocarcinoma
Mol Cell Proteomics. 2021 Aug 12:100136. doi: 10.1016/j.mcpro.2021.100136. Online ahead of print.ABSTRACTImmune checkpoint inhibitors and adoptive lymphocyte transfer-based therapies have shown great therapeutic potential in cancers with high tumor mutational burden (TMB), such as melanoma, but not in cancers with low TMB, such as mutant epidermal growth factor receptor (EGFR)-driven lung adenocarcinoma. Precision immunotherapy is an unmet need for most cancers, particularly for cancers that respond inadequately to immune checkpoint inhibitors. Here, we employed large-scale mass spectrometry (MS)-based proteogenomic profil...
Source: Molecular and Cellular Proteomics : MCP - August 15, 2021 Category: Molecular Biology Authors: Yue A Qi Tapan K Maity Constance M Cultraro Vikram Misra Xu Zhang Catherine Ade Shaojian Gao David Milewski Khoa D Nguyen Mohammad H Ebrahimabadi Ken-Ichi Hanada Javed Khan Cenk Sahinalp James C Yang Udayan Guha Source Type: research

Factors Associated With African American Mothers' Perceptions of Human Papillomavirus Vaccination of Their Daughters: An Integrated Literature Review
Oncol Nurs Forum. 2021 Jul 1;48(4):371-389. doi: 10.1188/21.ONF.371-389.ABSTRACTPROBLEM IDENTIFICATION: African American (AA) women have a higher mortality rate for cervical and other cancers and are less likely to have received the human papillomavirus (HPV) vaccine than White women. Mothers play a significant family role and have a unique relationship with their daughters. Mothers' positive views on HPV vaccination may enhance the HPV vaccination rate among their daughters.LITERATURE SEARCH: The review was conducted by searching literature in PubMed®, CINAHL®, ScienceDirect, Ovid MEDLINE®, and ProQuest databases. The ...
Source: Oncology Nursing Forum - June 18, 2021 Category: Nursing Authors: Stella Dike Wyona M Freysteinson Source Type: research

Proteogenomic analysis unveils the HLA Class I-presented immunopeptidome in melanoma and EGFR-mutant lung adenocarcinoma
Mol Cell Proteomics. 2021 Aug 12:100136. doi: 10.1016/j.mcpro.2021.100136. Online ahead of print.ABSTRACTImmune checkpoint inhibitors and adoptive lymphocyte transfer-based therapies have shown great therapeutic potential in cancers with high tumor mutational burden (TMB), such as melanoma, but not in cancers with low TMB, such as mutant epidermal growth factor receptor (EGFR)-driven lung adenocarcinoma. Precision immunotherapy is an unmet need for most cancers, particularly for cancers that respond inadequately to immune checkpoint inhibitors. Here, we employed large-scale mass spectrometry (MS)-based proteogenomic profil...
Source: Molecular and Cellular Proteomics : MCP - August 15, 2021 Category: Molecular Biology Authors: Yue A Qi Tapan K Maity Constance M Cultraro Vikram Misra Xu Zhang Catherine Ade Shaojian Gao David Milewski Khoa D Nguyen Mohammad H Ebrahimabadi Ken-Ichi Hanada Javed Khan Cenk Sahinalp James C Yang Udayan Guha Source Type: research

Factors Associated With African American Mothers' Perceptions of Human Papillomavirus Vaccination of Their Daughters: An Integrated Literature Review
Oncol Nurs Forum. 2021 Jul 1;48(4):371-389. doi: 10.1188/21.ONF.371-389.ABSTRACTPROBLEM IDENTIFICATION: African American (AA) women have a higher mortality rate for cervical and other cancers and are less likely to have received the human papillomavirus (HPV) vaccine than White women. Mothers play a significant family role and have a unique relationship with their daughters. Mothers' positive views on HPV vaccination may enhance the HPV vaccination rate among their daughters.LITERATURE SEARCH: The review was conducted by searching literature in PubMed®, CINAHL®, ScienceDirect, Ovid MEDLINE®, and ProQuest databases. The ...
Source: Oncology Nursing Forum - June 18, 2021 Category: Nursing Authors: Stella Dike Wyona M Freysteinson Source Type: research

A Systematic Review of Potential Immunotherapies Targeting PRAME in Retinoid Resistant Oral Potentially Malignant Disorders and Oral Cancer
Conclusion: Our analysis of the literature suggests that PRAME screening in OC and OPMDs prior to RBT should be done. In PRAME positive cases, approaches like PRAME based immunotherapy in the form of Cancer vaccine therapy [Acellular PRAME vaccine, PRAME pulsed Dendritic Cells (DC)]; Adoptive T Cell therapy/T Cell Receptor-T Cell therapy, Antibody therapy/Chimeric Antigen Receptor-T Cell therapy along with Presented antigen modulation Therapies employing histone deacetylase inhibitors and demethylation agents seem plausible. In the future, a combination therapy employing either PRAME vaccines or antibodies or Adoptive T ce...
Source: Current Molecular Medicine - October 29, 2021 Category: Molecular Biology Authors: Ruby Dwivedi Divya Mehrotra Shaleen Chandra Rahul Pandey Source Type: research