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Total 29834 results found since Jan 2013.

Treatment of chronic cluster headache with burst and tonic occipital nerve stimulation: A case series
CONCLUSION: Occipital nerve stimulation significantly reduced the number of weekly headache attacks and their intensity. Burst ONS seems to function well alone or as a supplement to conventional tonic ONS as a preventive treatment for CCH; however, larger prospective studies are needed to determine whether the effect can be confirmed and whether the efficacy of the two stimulation paradigms is even.PMID:37602914 | DOI:10.1111/head.14617
Source: Headache - August 21, 2023 Category: Neurology Authors: Ida Stisen Fogh-Andersen Jens Christian Hedemann S ørensen Rigmor H øjland Jensen Anne Lene Knudsen Kaare Meier Source Type: research

Where Art Thou O treatment for diabetic neuropathy: the sequel
This article challenges the rationale for the FDA insisting on symptoms/signs and nerve conduction as primary endpoints for clinical trials in DPN.EXPERT OPINION: Quantitative sensory testing, intraepidermal nerve fiber density, and especially corneal confocal microscopy remain an after-thought, demoted at best to exploratory secondary endpoints in clinical trials of diabetic neuropathy. If pharma are to be given a fighting chance to secure approval for a new therapy for diabetic neuropathy, the FDA needs to reassess the evidence rather than rely on 'opinion' for the most suitable endpoint(s) in clinical trials of diabetic...
Source: Expert Review of Neurotherapeutics - August 21, 2023 Category: Neurology Authors: Yigit Can Guldiken Ayesha Malik Ioannis N Petropoulos Hoda Gad Einas Elgassim Iuliia Salivon Georgios Ponirakis Uazman Alam Rayaz A Malik Source Type: research