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Procedure: Kidney Transplant

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Total 42950 results found since Jan 2013.

Vascular calcification--is aldosterone a culprit?
In chronic kidney disease (CKD), increased plasma phosphate concentrations cause vascular calcification which substantially contribute to cardiovascular events and increased mortality of CKD patients. Similar to CKD patients, klotho-hypomorphic mice (kl/kl) also suffer from excessive vascular calcification leading to growth deficit, rapid ageing and early death. The hyperphosphataemia of kl/kl mice results from excessive formation of 1,25(OH)2D3 causing excessive intestinal phosphate absorption. Further, kl/kl mice further suffer from hyperaldosteronism and compelling evidence points to an active role of mineralocorticoids...
Source: Nephrology Dialysis Transplantation - May 14, 2013 Category: Urology & Nephrology Authors: Lang, F., Ritz, E., Voelkl, J., Alesutan, I. Tags: REVIEWS - CLINICAL SCIENCE AND OUTCOME RESEARCH IN NEPHROLOGY Source Type: research

Complications and Graft Survival in Kidney Transplants With Vascular Variants: Our Experience and Literature Review
This article reports our experience in kidney transplants with vascular anomalies.Materials and methods: Between January 1996 and June 2012, 154 cadaveric kidney transplantations were performed at our center. In 35 case, vascular variants were found. Among the arterial variants we observed 27 double arteries, 2 cases with 3 arteries, and 1 case with 4 arteries. All cases of Venous variants were double veins. Based on the type of reconstructive technique used, we divided transplants into group A (n = 22) separate multiple arterial anastomoses; group B (n = 8) anastomosis on the aortic patch; group C (n = 4) single anasto...
Source: Transplantation Proceedings - September 1, 2013 Category: Transplant Surgery Authors: S. Vaccarisi, E. Bonaiuto, N. Spadafora, A. Garrini, V. Crocco, M. Cannistrà, V. Pellegrino, G. Cavallari, B. Nardo Tags: Renal Transplantation Source Type: research

The association of long-functioning hemodialysis vascular access with prevalence of left ventricular hypertrophy in kidney transplant recipients.
This study evaluates the impact of long-functioning hemodialysis vascular access on LVH in single center cohort of kidney transplant recipients. 162 patients at 8.7 ± 1.8 years after kidney transplantation were enrolled. Echocardiography, carotid ultrasound, and assessment of pulse wave velocity were performed. LVH was defined based on left ventricular mass (LVM) indexed for body surface area (BSA) and height(2.7). There were 67 patients with and 95 without patent vascular access. Both study groups were comparable with respect to gender, age, duration of dialysis therapy, and time after transplantation, kidney graft funct...
Source: Biomed Res - March 15, 2014 Category: Research Authors: Kolonko A, Kujawa-Szewieczek A, Szotowska M, Kuczera P, Chudek J, Więcek A Tags: Biomed Res Int Source Type: research

Vascular challenges in renal transplantation.
Conclusions The demand for renal transplants has led to more marginal-quality organs and older donors and/or recipients waiting for a second or third transplantation. Thus, the expertise of a vascular surgeon is extremely helpful in a transplantation center because it allows for marginal organ transplantation with acceptable 5-year graft survival rates. PMID: 25234743 [PubMed - in process]
Source: Annals of Transplantation - September 28, 2014 Category: Transplant Surgery Authors: Sagban TA, Baur B, Schelzig H, Grabitz K, Duran M Tags: Ann Transplant Source Type: research

Role of Mesenchymal Stem Cells Transfected With Vascular Endothelial Growth Factor in Maintaining Renal Structure and Function in Rats with Unilateral Ureteral Obstruction.
CONCLUSIONS: Systemic stem cells transplanted into the kidney protected against unilateral ureteral obstruction-induced renal epithelial-mesenchymal transition and renal fibrosis. PMID: 25542189 [PubMed - as supplied by publisher]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - December 22, 2014 Category: Transplant Surgery Authors: Ozbek E, Adas G, Otunctemur A, Duruksu G, Koc B, Polat EC, Kemik Sarvan A, Okcu A, Kamali G, Subasi C, Karaoz E Tags: Exp Clin Transplant Source Type: research

NASA and New Organ Develop the Vascular Tissue Challenge
The news for today is that NASA's Centennial Challenges Program and the Methuselah Foundation's tissue engineering initiative New Organ have joined forces to develop the Vascular Tissue Challenge, which is currently public in a draft form as an RFI. The intent is to divide a $500,000 purse between up to three teams who can advance the state of the art in tissue engineering by reliably producing thick sections of vascularized living tissue. I'm sure you've all seen the announcements roll in over the past few years as research groups have built small organoids that function correctly for their organ type: slivers of pancrea...
Source: Fight Aging! - March 20, 2016 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs

The diagnostic value of contrast-enhanced ultrasound (CEUS) as a new technique for imaging of vascular complications in renal transplants compared to standard imaging modalities.
CONCLUSIONS: CEUS is a non-nephrotoxic and safe method for the initial imaging of vascular complications in renal transplant recipients. Compared to the gold standard imaging modalities CT, DSA and radioisotope renography CEUS shows a high sensitivity and NPV in detecting vascular complications. In cases with suspected stenosis of the transplant renal artery additional DSA might be needed. PMID: 28885208 [PubMed - as supplied by publisher]
Source: Clinical Hemorheology and Microcirculation - September 4, 2017 Category: Hematology Authors: Mueller-Peltzer K, Rübenthaler J, Fischereder M, Reiser M, Clevert DA Tags: Clin Hemorheol Microcirc Source Type: research

The effect of an educational program for vascular access care on nurses' knowledge at dialysis centers in Khartoum State, Sudan.
This study was to evaluate the effect of an educational program for vascular access care on nurses' knowledge at nine dialysis centers in Khartoum State. This was a Quasi experimental study (pre-and post-test for the same group). Sixty-one nurses working in these HD centers were chosen by simple random sampling method. A structured face-to-face interview questionnaire based on the Kidney Dialysis Outcome Quality Initiative (K/DOQI) clinical practice guidelines for vascular access care was used. Instrument validity was determined through content validity by a panel of experts. Reliability of the instrument was tested by a p...
Source: Saudi Journal of Kidney Diseases and Transplantation - September 1, 2017 Category: Urology & Nephrology Authors: Yousif KI, Abu-Aisha H, Abboud OI Tags: Saudi J Kidney Dis Transpl Source Type: research

Impact of Surgeon's Experience on Vascular and Haemorrhagic Complications After Kidney Transplantation.
CONCLUSIONS: The surgeon's experience is an independent risk factor for vascular and haemorrhagic complications after KTx. Acceptable post-operative vascular and haemorrhagic complications are achieved after a minimum of 26 KTx. As a donor age of >60 years and recipient CVD are also independent risk factors for vascular and haemorrhagic complications, it is suggested that these patients should preferably be operated on by surgeons who have performed more than 26 KTx operations. PMID: 30236441 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - September 17, 2018 Category: Surgery Authors: Kulu Y, Fathi P, Golriz M, Khajeh E, Sabagh M, Ghamarnejad O, Mieth M, Ulrich A, Hackert T, Müller-Stich BP, Strobel O, Michalski C, Morath C, Zeier M, Büchler MW, Mehrabi A Tags: Eur J Vasc Endovasc Surg Source Type: research

Disruptive technological advances in vascular access for dialysis: an overview
AbstractEnd-stage kidney disease (ESKD), one of the most prevalent diseases in the world and with increasing incidence, is associated with significant morbidity and mortality. Current available modes of renal replacement therapy (RRT) include dialysis and renal transplantation. Though renal transplantation is the preferred and ideal mode of RRT, this modality may not be available to all patients with ESKD. Moreover, renal transplant recipients are constantly at risk of complications associated with immunosuppression and immunosuppressant use, and posttransplant lymphoproliferative disorder. Dialysis may be the only availab...
Source: Pediatric Nephrology - October 25, 2018 Category: Urology & Nephrology Source Type: research

Current state of dialysis access management in Korea.
Authors: Kim YS, Kim Y, Shin SJ, Lee HS, Kim SG, Cho S, Na KR, Kim JK, Kim SJ, Kim YO, Jin DC Abstract The prevalence rate and the incidence rate of hemodialysis and functioning kidney transplant recipients have continuously increased; on the contrary, those of peritoneal dialysis have continuously decreased since 2006. Dialysis patients have been getting older and have been maintained on dialysis longer. Diabetic nephropathy was the leading cause of end stage renal disease. The type of hemodialysis vascular access has been stable during the last 5 years (arteriovenous fistulas 76%, arteriovenous grafts 16%, cent...
Source: The Journal of Vascular Access - May 1, 2019 Category: Surgery Tags: J Vasc Access Source Type: research

Effect of Spironolactone for One Year on Endothelial Function and Vascular Inflammation Biomarkers in Renal Transplant Recipients.
CONCLUSIONS: MR blockade did not improve biomarkers of endothelial dysfunction or vascular inflammation in renal transplant patients. Since no beneficial effect of MR blockade on vascular biomarkers was found, aldosterone is likely not a major promoter of vascular dysfunction in renal transplant patients. PMID: 31166706 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Renal Physiology - June 4, 2019 Category: Physiology Authors: Mortensen LA, Bistrup C, Stubbe J, Carlström M, Checa A, Wheelock CE, Palarasah Y, Bladbjerg EM, Thiesson HC, Jensen BL Tags: Am J Physiol Renal Physiol Source Type: research

Vascular Access Choice, Complications, and Outcomes in Children on Maintenance Hemodialysis: Findings From the International Pediatric Hemodialysis Network (IPHN) Registry
ConclusionsCVCs are the predominant vascular access choice in children receiving HD within the IPHN. Age-related anatomical limitations and expected early living related transplantation were associated with CVC use. CVCs were associated with poorer dialysis efficacy, higher complication rates, and more frequent need for vascular access replacement. Such findings call for a re-evaluation of pediatric CVC use and practices.
Source: American Journal of Kidney Diseases - June 20, 2019 Category: Urology & Nephrology Source Type: research

Renal transplantation using vascular conduit reconstruction in deceased kidneys with multiple renal arteries and short renal veins.
CONCLUSIONS: Vascular reconstruction using arterial and venous grafts harvested from the same deceased donor may result a helpful tool to simplify vascular anastomoses during transplantation surgery, thus avoiding their discard in advance, minimizing perioperative complications, and enabling normal graft function rates in the long-term follow-up. The successful outcome obtained by using this approach would help to expand the donor criteria for the inclusion of organs containing vascular anatomical variants. PMID: 32534829 [PubMed - as supplied by publisher]
Source: Actas Urologicas Espanolas - June 10, 2020 Category: Urology & Nephrology Authors: Alexander A, Serena G, González J, DeFaria W, Ciancio G Tags: Actas Urol Esp Source Type: research

Serum Osteocalcin Level is Negatively Associated with Vascular Reactivity Index by Digital Thermal Monitoring in Kidney Transplant Recipients.
CONCLUSIONS: Higher serum osteocalcin level was associated with lower VRI and poorer endothelial dysfunction among KT recipients. PMID: 32784817 [PubMed - in process]
Source: Medicina (Kaunas) - August 8, 2020 Category: Universities & Medical Training Authors: Lin L, Chiu LT, Lee MC, Hsu BG Tags: Medicina (Kaunas) Source Type: research