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Total 83462 results found since Jan 2013.

Application of lipid and polymeric-based nanoparticles for treatment of inner ear infections via XGBoost
Environ Res. 2023 Sep 15:117115. doi: 10.1016/j.envres.2023.117115. Online ahead of print.ABSTRACTTaking hearing loss as a prevalent sensory disorder, the restricted permeability of blood flow and the blood-labyrinth barrier in the inner ear pose significant challenges to transporting drugs to the inner ear tissues. The current options for hear loss consist of cochlear surgery, medication, and hearing devices. There are some restrictions to the conventional drug delivery methods to treat inner ear illnesses, however, different smart nanoparticles, including inorganic-based nanoparticles, have been presented to regulate dru...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Jie Zhang Chen Ru Shuainan Chen Die Yu Dalia H Elkamchouchi Mohammed S Alqahtani Hamid Assilzadeh Zhongguan Huang Yideng Huang Source Type: research

Tidal flat microbial communities between the Huaihe estuary and Yangtze River estuary
Environ Res. 2023 Sep 15:117141. doi: 10.1016/j.envres.2023.117141. Online ahead of print.ABSTRACTTidal flats have important ecological functions and offer great economic value. Using field sampling, numerical simulation, and high-throughput sequencing, the ecological state of typical tidal flats along the eastern coast of China was investigated. The findings demonstrated that the area may be separated into subregions with notable differences in the features of microbial communities due to the variations in water quality and total pollutant discharge of seagoing rivers. With a ratio of 62%, the development of the microbial...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Weiwei Song Yi Li Source Type: research

Efficacy of a novel glioma therapy based on ferroptosis induced by layered double hydroxide loaded with simvastatin
In this study, folic acid (FA)-modified layered double hydroxide loaded with simvastatin (SIM), a ferroptosis drug, was used to prepare a novel ferroptosis nanodrug (FA-LDH@SIM). The prepared nanodrug improved the therapeutic effect of SIM on glioma. Compared with free SIM, FA-LDH@SIM showed greater cytotoxicity, significantly inhibited glioma cell proliferation, and significantly inhibited glioma invasion and migration ability. Furthermore, SIM could induce changes in certain ferroptosis indicators, including increased intracellular LPO, ROS and MDA level, decreased GSH production, increased divalent iron level, and chang...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Wei Peng Yufeng Qian Xuchen Qi Source Type: research

ZnO/black phosphorus/C < sub > 3 < /sub > N < sub > 4 < /sub > composite: An effective photocatalyst for Cr (VI) reduction and degradation of rhodamine B
Environ Res. 2023 Sep 15:117122. doi: 10.1016/j.envres.2023.117122. Online ahead of print.ABSTRACTWe have synthesized an n-p-n heterojunction of carbon nitride (C3N4), zinc oxide (ZnO), and black phosphorus (BP) through the sonication-stirring method. The photocatalytic ability of this composite was examined for the decomposition rhodamine B (RhB) and detoxification of hexavalent chromium ion (up to 97% during 80 min) under Xenon irradiation. The results of trapper experiments indicated that the active species were hydroxyl radical (˙OH), electron (e-), and superoxide anion radical (˙O2-). Based on the obtained potential...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Sahar Moradian Ghodsi Mohammadi Ziarani Alireza Badiei Siavash Iravani Source Type: research

Current appraises of therapeutic applications of nanocurcumin: A novel drug delivery approach for biomaterials in dentistry
Environ Res. 2023 Sep 15:116971. doi: 10.1016/j.envres.2023.116971. Online ahead of print.ABSTRACTCurcumin is a natural herb and polyphenol that is obtained from the medicinal plant Curcuma longa. It's anti-bacterial, anti-inflammatory, anti-cancer, anti-mutagenic, antioxidant and antifungal properties can be leveraged to treat a myriad of oral and systemic diseases. However, natural curcumin has weak solubility, limited bioavailability and undergoes rapid degradation, which severely limits its therapeutic potential. To overcome these drawbacks, nanocurcumin (nCur) formulations have been developed for improved biomaterial ...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Ranjeet A Bapat Sumit V Bedia Aarti S Bedia Ho Jan Yang Suyog Dharmadhikari Anshad Mohamed Abdulla Tanay V Chaubal Prachi R Bapat Shahabe Saquib Abullais Shadma Wahab Prashant Kesharwani Source Type: research

Cross-regional ecological compensation under the composite index of water quality and quantity: A case study of the Yellow River Basin
Environ Res. 2023 Sep 15:117152. doi: 10.1016/j.envres.2023.117152. Online ahead of print.ABSTRACTThe calculation of ecological compensation (EC) constitutes the core element of the EC mechanism, which is related to the practicability of the mechanism. Based on the comprehensive index of water quality and quantity, this study establishes a measurement method for EC across administrative divisions. First, the improved Nemerow pollution index (NPI) is adopted to assess the water quality of specific sections, while the water rights and GDP indicators are employed to characterize the water quantity of each section. Secondly, g...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Hao Hu Guiliang Tian Zheng Wu Qing Xia Source Type: research

Nanoparticles-assisted aptamer biosensing for the detection of environmental pathogens
Environ Res. 2023 Sep 15:117123. doi: 10.1016/j.envres.2023.117123. Online ahead of print.ABSTRACTGiven the importance of public health, it is crucial to develop quick, targeted, highly sensitive, and accurate technologies to monitor pathogenic microbes in response to the growing concerns of food and environmental safety. Although conventional approaches for microbiological detection are available, they are laborious, and often skill demanding. Therefore, such approaches are incompetent in the on-site or high-throughput assessment of pathogenic microbes. Numerous efforts have been made to develop biosensors that use nuclei...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Kamal Rahimizadeh Qurat Ul Ain Zahra Suxiang Chen Bao T Le Ismat Ullah Rakesh N Veedu Source Type: research

Phytotoxicity of weathered petroleum hydrocarbons in soil to boreal plant species
This study indicates that natural weathering of Fraction 2- and Fraction 3-concentrated soil did not eliminate phytotoxicity to boreal plant species. Furthermore, it builds on the limited existing literature for toxicity of PHCs on boreal plants and supports site remediation to existing Canadian provincial PHC guidelines.PMID:37717802 | DOI:10.1016/j.envres.2023.117136
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Prama Roy Allison Rutter Amy Gainer Elizabeth Haack Barbara A Zeeb Source Type: research

Prediction of carbon emissions peak and carbon neutrality based on life cycle CO < sub > 2 < /sub > emissions in megacity building sector: Dynamic scenario simulations of Beijing
Environ Res. 2023 Sep 15:117160. doi: 10.1016/j.envres.2023.117160. Online ahead of print.ABSTRACTIn order to design an optimal carbon peak and carbon neutralization pathway for the high-density building sector, a dynamic prediction model is established using system-dynamics coupled building life cycle carbon emission model (SD-BLCA) with consideration of future evolutionary trajectory and time constraints. The model is applied in Beijing using the SD-BLCA combined with scenario analysis and Monte Carlo methods to explore optimal trajectory for its building sector under 30-year timeframe. The results indicate that by incre...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Li Xin Sinuo Li Eldon R Rene Xiaoxiu Lun Panyue Zhang Weifang Ma Source Type: research

Joint effects of prenatal exposure to air pollution and pregnancy-related anxiety on birth weight: A prospective birth cohort study in Ma' anshan, China
CONCLUSION: Using the method of analyzing mixed exposures, we found that during pregnancy, the combined exposure of air pollutants and PrA, particularly during trimester 1, is associated with BWz decrease. This supports the view that prenatal exposure to chemical and non-chemical stressors has an impact on fetal growth.PMID:37717800 | DOI:10.1016/j.envres.2023.117161
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Zhen-Hua Li Yi-Cheng Mao Yang Li Sun Zhang Hui-Yu Hu Zhe-Ye Liu Xue-Jie Liu Jia-Wen Zhao Kai Huang Mao-Lin Chen Guo-Peng Gao Cheng-Yang Hu Xiu-Jun Zhang Source Type: research

Building parameters linked with indoor transmission of SARS-CoV-2
Environ Res. 2023 Sep 15:117156. doi: 10.1016/j.envres.2023.117156. Online ahead of print.ABSTRACTThe rapid spread of Coronavirus Disease (2019)(COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emphasized the importance of understanding and adapting to the indoor remediation of transmissible diseases to decrease the risk for future pandemic threats. While there were many precautions in place to hinder the spread of COVID-19, there has also been a substantial increase of new research on SARS-CoV-2 that can be utilized to further mitigate the transmission risk of this novel virus. This r...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Jacqueline Horne Nicholas Dunne Nirmala Singh Md Safiuddin Navid Esmaeili Merve Erenler Ian Ho Edwin Luk Source Type: research

Mercury causes degradation of spatial cognition in a model songbird species
Ecotoxicol Environ Saf. 2023 Sep 15;264:115483. doi: 10.1016/j.ecoenv.2023.115483. Online ahead of print.ABSTRACTMercury is a widespread pollutant of increasing global concern that exhibits a broad range of deleterious effects on organisms, including birds. Because the developing brain is well-known to be particularly vulnerable to the neurotoxic insults of mercury, many studies have focused on developmental effects such as on the embryonic brain and resulting behavioral impairment in adults. It is not well understood how the timing of exposure, for example exclusively in ovo versus throughout life, influences the impact o...
Source: Ecotoxicology and Environmental Safety - September 17, 2023 Category: Environmental Health Authors: Cara N Brittain Amanda M Bessler Andrew S Elgin Rachel B Layko Sumin Park Shelby E Still Haruka Wada John P Swaddle Daniel A Cristol Source Type: research

Extremely low-frequency electromagnetic field induces acetylation of heat shock proteins and enhances protein folding
Ecotoxicol Environ Saf. 2023 Sep 15;264:115482. doi: 10.1016/j.ecoenv.2023.115482. Online ahead of print.ABSTRACTThe pervasive weak electromagnetic fields (EMF) inundate the industrialized society, but the biological effects of EMF as weak as 10 µT have been scarcely analyzed. Heat shock proteins (HSPs) are molecular chaperones that mediate a sequential stress response. HSP70 and HSP90 provide cells under undesirable situations with either assisting covalent folding of proteins or degrading improperly folded proteins in an ATP-dependent manner. Here we examined the effect of extremely low-frequency (ELF)-EMF on AML12 and ...
Source: Ecotoxicology and Environmental Safety - September 17, 2023 Category: Environmental Health Authors: Zhizhou Huang Mikako Ito Shaochuan Zhang Takuro Toda Jun-Ichi Takeda Tomoo Ogi Kinji Ohno Source Type: research

Lead exposure disrupted ileal barrier of developmental Japanese quails(Coturnix japonica): Histopathological damages, microbiota dysbiosis and immune disorder
Ecotoxicol Environ Saf. 2023 Sep 15;264:115488. doi: 10.1016/j.ecoenv.2023.115488. Online ahead of print.ABSTRACTThe gut barrier plays an essential role in maintaining homeostasis and is usually composed of a mechanical barrier, a chemical barrier, an immune barrier, and a biological barrier. However, the impacts of lead (Pb) exposure on avian gut barrier are still unclear. Therefore, the present study tried to determine the toxic effects of Pb on ileal barrier of a biological model-Japanese quail (Coturnix japonica). One-week old quails were exposed to 0, 50, 500 and 1000 ppm Pb in drinking water for 5 weeks. The results ...
Source: Ecotoxicology and Environmental Safety - September 17, 2023 Category: Environmental Health Authors: Ying Zheng Mingcun Chen Yuxin Zhang Gang Wang Hongfeng Zhao Source Type: research

Ultrastructural characteristics of the accumulation of iron nanoparticles in the intestine of Cyprinus carpio (Linnaeus, 1758) under aquaculture
Ecotoxicol Environ Saf. 2023 Sep 15;264:115477. doi: 10.1016/j.ecoenv.2023.115477. Online ahead of print.ABSTRACTDuring the development of nanotechnology, the production of many substances containing nanoparticles leads to the release of various nanoparticles into the environment, including the water ecosystem. The main goal of the current research was to study the ultrastructural characteristics of the entry and bioaccumulation of Fe3O4 nanoparticles in the small intestine of Cyprinus carpio (Linnaeus, 1758), as well as the pathomorphological changes in the fish organism. Two different doses (10 and 100 mg) of Fe3O4 nanop...
Source: Ecotoxicology and Environmental Safety - September 17, 2023 Category: Environmental Health Authors: Aysel Hajiyeva Chingiz Mamedov Eldar Gasimov Fuad Rzayev Rovshan Khalilov Elham Ahmadian Aziz Eftehari William C Cho Source Type: research