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Vaccination: Influenza Vaccine

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Total 6581 results found since Jan 2013.

Vaccination of Older Adults with Dementia Against Respiratory Infections.
Abstract People with dementia are at a greater risk of complications from respiratory infections therefore can benefit from vaccinations against influenza, pneumococcal disease and pertussis. This review aimed to evaluate the uptake and impact of vaccination in older adults with dementia against respiratory infections and identify knowledge gaps. Key databases were explored, search results were assessed, relevant studies identified, and data were synthesised and summarised. Most available data suggest that older adults with dementia are less likely to receive influenza or pneumococcal vaccine while a few studies i...
Source: Infectious Disorders Drug Targets - July 13, 2014 Category: Infectious Diseases Authors: Ridda I, Dastouri F, King C, Yin JK, Tashani M, Rashid H Tags: Infect Disord Drug Targets Source Type: research

Fetal death and preterm birth associated with maternal influenza vaccination: systematic review.
CONCLUSIONS: Most studies reported no association between fetal death or preterm birth and influenza vaccination during pregnancy. Although several reported risk reductions, results may be biased by methodological shortcomings of observational studies of influenza vaccine effectiveness. PMID: 25040307 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - July 10, 2014 Category: OBGYN Authors: Fell D, Platt R, Lanes A, Wilson K, Kaufman J, Basso O, Buckeridge D Tags: BJOG Source Type: research

Haemophilus influenzae oral vaccination for preventing acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease.
CONCLUSIONS: Analyses demonstrate that NTHi oral vaccination of patients with recurrent exacerbations of chronic bronchitis or COPD does not yield a significant reduction in the number and severity of exacerbations. Evidence is mixed and the individual trials that show a significant benefit of the vaccine are too small to advocate widespread oral vaccination of people with COPD. PMID: 25201571 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - September 9, 2014 Category: Journals (General) Authors: Teo E, House H, Lockhart K, Purchuri SN, Pushparajah J, Cripps AW, van Driel ML Tags: Cochrane Database Syst Rev Source Type: research

Multi-dose flu shot has only 25 mcg of mercury - most commercial fish contain 23 mcg of mercury per 8 ounces of fish
http://buff.ly/11CTRPwAre multi-dose vials less expensive?Economics are a bit complicated due to wastage with multiple vials:Single versus multi-dose vaccine vials: an economic computational modelhttp://www.ncbi.nlm.nih.gov/pubmed/20566395Most of the Western world, apart from the US, has moved on to single vials:http://www.medscape.com/viewarticle/733986Whenever possible, CDC recommends that single-use vials be used and that multi-dose vials of medication be assigned to a single patient to reduce the risk of disease transmission (http://www.cdc.gov/injectionsafety/patients/syringeReuse_faqs.html).Where to get a thimerosal...
Source: Clinical Cases and Images - October 21, 2014 Category: Journals (General) Tags: Vaccines Source Type: news

Evans Syndrome Presented with Marginal Zone Lymphoma and Duodenal Neuroendocrine Tumor in an Elderly Woman
We report a case of ES in an elderly patient in the presence of multiple trigger factors such as recent influenza vaccine, marginal zone lymphoma, and neuroendocrine tumor G1. Whether this association is casual or causal remains a matter of speculation. It is however necessary to have a thorough work-up in a newly diagnosed ES and a more accurate search of miscellaneous factors especially in elderly patients.
Source: International Journal of Gerontology - October 12, 2014 Category: Geriatrics Source Type: research

Influenza Vaccine To Prevent Adverse Vascular Events: A Pilot Study
Condition:   Heart FailureIntervention:   Drug: inactivated trivalent influenza vaccineSponsor:   McMaster UniversityNot yet recruiting - verified October 2014
Source: ClinicalTrials.gov - September 13, 2013 Category: Research Source Type: clinical trials

Comparative Study of Immunogenicity of Split, Intradermal and MF59-adjuvanted Influenza Vaccines in Elderly Institutionalized Subjects
In conclusion the use of MF59 adjuvant and intradermal vaccination appear to be appropriate strategies to address the challenge of declining immune response in the elderly after influenza vaccination.
Source: Procedia in Vaccinology - October 13, 2014 Category: Infectious Diseases Source Type: research

Neuroimmunology: Disease mechanisms in narcolepsy remain elusive
Nature Reviews Neurology 10, 616 (2014). doi:10.1038/nrneurol.2014.191 Authors: Ilkka Julkunen & Markku Partinen A pandemic influenza vaccine with a specific type of vaccine antigen has been linked to an increased incidence of narcolepsy in children from 2009–2010. However, the recent retraction of an article that reported a putative autoantigen means that the search for the mechanisms behind the vaccine–narcolepsy connection continues.
Source: Nature Reviews Neurology - October 14, 2014 Category: Neurology Authors: Ilkka JulkunenMarkku Partinen Tags: News and Views Source Type: research

Influenza Vaccine To Prevent Adverse Vascular Events: A Pilot Study
Condition:   Heart FailureIntervention:   Drug: inactivated trivalent influenza vaccineSponsor:   McMaster UniversityNot yet recruiting - verified October 2014
Source: ClinicalTrials.gov - September 13, 2013 Category: Research Source Type: clinical trials

Healthcare Update Satellite — 12-16-2014
Answering the important questions … why does the flu vaccine suck this year? Keep a lookout for next month’s issue of EP Monthly which will tell you everything you need to know about influenza diagnosis and treatment. Of course, if you had read the backboard article in EP Monthly’s November issue, you’d already be doing this … Florida fire department abandons use of backboards for most trauma patients. 4 year old boy develops carotid artery dissection and left sided hemiparesis after riding a roller coaster. Fortunately, he had made significant recovery by six months. How scary is that, though...
Source: WhiteCoat's Call Room - December 17, 2014 Category: Emergency Medicine Authors: WhiteCoat Tags: Healthcare Update Source Type: blogs

2014: The Year of the Virus
Ebola is now a dreaded household name. Everyone has heard of this virus, causing thousands of deaths in countries in Africa particularly in Guinea, Liberia and Sierra Leone. We followed the plight of health care workers who put their lives on the line to battle the viral disease, trying to prevent the virus from spreading to the next host. But what about the Enterovirus D68? And what about Chlorovirus, Densovirus, Porcine Epidemic Diarrhea Virus and Ranavirus? (See Bullets below). Our understanding of the viral world is severely limited. Viruses are the most numerous and diverse entities on earth with estimates of 1.7 bi...
Source: Science - The Huffington Post - January 13, 2015 Category: Science Source Type: news

Post-licensure surveillance of quadrivalent live attenuated influenza vaccine United States, Vaccine Adverse Event Reporting System (VAERS), July 2013-June 2014.
CONCLUSIONS: Our analysis of VAERS reports for LAIV4 did not identify any concerning patterns. The data mining finding for reports of influenza illness is consistent with low LAIV4 vaccine effectiveness observed for influenza A disease in children in 2013-2014. Reports of LAIV4 administration to persons in whom the vaccine is not recommended (e.g., pregnant women) indicate the need for education, training and screening regarding indications. PMID: 25678241 [PubMed - as supplied by publisher]
Source: Vaccine - February 9, 2015 Category: Allergy & Immunology Authors: Haber P, Moro PL, Cano M, Lewis P, Stewart B, Shimabukuro TT Tags: Vaccine Source Type: research

Maternal Influenza Immunization and Birth Outcomes of Stillbirth and Spontaneous Abortion: A Systematic Review and Meta-analysis
Despite strong evidence that maternal influenza vaccination during pregnancy is safe, uptake of influenza vaccination during pregnancy remains low. We identified studies that assessed outcomes of stillbirth or spontaneous abortion after administration of influenza vaccine during pregnancy. We conducted a literature search in November 2013 that yielded 447 total citations. After removal of duplicates and studies deemed not relevant based on the title and abstract, 36 records underwent a full text review and 7 studies were included in the final review. Where possible, adjusted results were included in the meta-analysis. Wome...
Source: Clinical Infectious Diseases - February 16, 2015 Category: Infectious Diseases Authors: Bratton, K. N., Wardle, M. T., Orenstein, W. A., Omer, S. B. Tags: ELECTRONIC ARTICLE Source Type: research

Influenza vaccination during pregnancy: A systematic review of fetal death, spontaneous abortion, and congenital malformation safety outcomes.
CONCLUSIONS: Results do not indicate that maternal influenza vaccination is associated with an increased risk of fetal death, spontaneous abortion, or congenital malformations. Statistical imprecision and clinical and methodological heterogeneity of the observational studies mean it is not possible to totally exclude adverse effects. Further studies investigating women vaccinated during their first trimester should be the highest priority to allow for more precise estimates, especially for spontaneous abortion, and congenital abnormality outcomes. PMID: 25758932 [PubMed - as supplied by publisher]
Source: Vaccine - March 7, 2015 Category: Allergy & Immunology Authors: McMillan M, Porritt K, Kralik D, Costi L, Marshall H Tags: Vaccine Source Type: research

Influenza vaccines for preventing acute otitis media in infants and children.
CONCLUSIONS: Influenza vaccine results in a small reduction in AOM. The observed reduction with the use of antibiotics needs to be considered in the light of current recommended practices aimed at avoiding antibiotic overuse. Safety data from these trials are limited. The benefits may not justify the use of influenza vaccine without taking into account the vaccine efficacy in reducing influenza and safety data. The quality of the evidence was high to moderate. Additional research is needed. PMID: 25803008 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - March 24, 2015 Category: Journals (General) Authors: Norhayati MN, Ho JJ, Azman MY Tags: Cochrane Database Syst Rev Source Type: research