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Therapy: Stem Cell Therapy
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Extracellular Vesicle Mediated Vascular Pathology in Glioblastoma
Subcell Biochem. 2021;97:247-273. doi: 10.1007/978-3-030-67171-6_10.ABSTRACTGlioblastoma (GBM) is an incurable, infiltrative high-grade brain tumour associated with dramatic vascular responses observed both locally (angiogenesis, vascular cooption, angiocrine effects, microthrombosis) and systemically (venous thromboembolism). GBM-associated vascular pathology is diagnostically relevant and constitutes a source of morbidity, mortality and progressive changes in tumour biology. Extracellular vesicles (EVs) have emerged as unique mediators of vascular effects in brain tumours acting as vehicles for intercellular transfer of ...
Source: Sub-Cellular Biochemistry - March 29, 2021 Category: Biochemistry Authors: Cristiana Spinelli Nadim Tawil Lata Adnani Janusz Rak Dongsic Choi Source Type: research
Human amniotic fluid stem cells can improve cerebral vascular remodelling and neurological function after focal cerebral ischaemia in diabetic rats
J Cell Mol Med. 2021 Oct 7. doi: 10.1111/jcmm.16956. Online ahead of print.ABSTRACTDiabetes causes vascular injury and carries a high risk of ischaemic stroke. Human amniotic fluid stem cells (hAFSCs) can enhance cerebral vascular remodelling and have the potential to improve neurological function after stroke in diabetic rats. Five groups of female rats were examined: (1) normal control, (2) type 1 diabetic (T1DM) rats induced by streptozotocin injection (DM), (3) non-DM rats receiving 60-minute middle cerebral artery occlusion (MCAO), (4) T1DM rats receiving 60-minute MCAO (DM + MCAO) and (5) T1DM rats receiving 60-minut...
Source: J Cell Mol Med - October 8, 2021 Category: Molecular Biology Authors: Ching-Chung Liang Steven W Shaw Yung-Hsin Huang Tsong-Hai Lee Source Type: research
Extracellular Vesicle Mediated Vascular Pathology in Glioblastoma
Subcell Biochem. 2021;97:247-273. doi: 10.1007/978-3-030-67171-6_10.ABSTRACTGlioblastoma (GBM) is an incurable, infiltrative high-grade brain tumour associated with dramatic vascular responses observed both locally (angiogenesis, vascular cooption, angiocrine effects, microthrombosis) and systemically (venous thromboembolism). GBM-associated vascular pathology is diagnostically relevant and constitutes a source of morbidity, mortality and progressive changes in tumour biology. Extracellular vesicles (EVs) have emerged as unique mediators of vascular effects in brain tumours acting as vehicles for intercellular transfer of ...
Source: Sub-Cellular Biochemistry - March 29, 2021 Category: Biochemistry Authors: Cristiana Spinelli Nadim Tawil Lata Adnani Janusz Rak Dongsic Choi Source Type: research
