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Vaccination: Influenza Vaccine

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Total 6581 results found since Jan 2013.

Vaccination recommendations for the adult immunosuppressed patient: A systematic review and comprehensive field synopsis.
CONCLUSION: Pneumococcal and injectable influenza are the two essential vaccines recommended in all immunocompromised patients. Other inactivated vaccines are only indicated in high risk patients. Live vaccines are usually contraindicated. PMID: 28381345 [PubMed - as supplied by publisher]
Source: Journal of Autoimmunity - April 2, 2017 Category: Allergy & Immunology Authors: Lopez A, Mariette X, Bachelez H, Belot A, Bonnotte B, Hachulla E, Lahfa M, Lortholary O, Loulergue P, Paul S, Roblin X, Sibilia J, Blum M, Danese S, Bonovas S, Peyrin-Biroulet L Tags: J Autoimmun Source Type: research

How Common is α -1-Antitrypsin Deficiency?
Discussion α-1-Antitrypsin Deficiency (A1AT) is a common single-gene mutation disease that is homozygous recessive. The normal allele is called M and the most common abnormal allele is Z. There are other alleles though. The gene codes for one of the primary protease inhibitors in the serum, thus those who are homozygous for the Z gene are sometimes referred to as “PIZZ” or “PIZ.” α-1-Antitrypsin is found in all body tissues but is especially important in the serum and lung. As noted it is one of the primary neutrophil protease inhibitors in the serum, and acts to neutralize these enzymes...
Source: PediatricEducation.org - April 24, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Improving adult immunization equity: Where do the published research literature and existing resources lead?
Abstract Evidence suggests that disparities in adult immunization (AI) rates are growing. Providers need adequate patient resources and information about successful interventions to help them engage in effective practices to reduce AI disparities. The primary purposes of this paper were to review and summarize the evidence base regarding interventions to reduce AI disparities and to scan for relevant resources that could support providers in their AI efforts to specifically target disparities. First, building on a literature review conducted by the U.S. Centers for Disease Control and Prevention, we searched the p...
Source: Vaccine - April 25, 2017 Category: Allergy & Immunology Authors: Prins W, Butcher E, Hall LL, Puckrein G, Rosof B Tags: Vaccine Source Type: research

A systematic review and meta-analysis of cross-reactivity of antibodies induced by oil-in-water emulsion adjuvanted influenza H5N1 virus monovalent vaccines.
CONCLUSIONS: OWEA influenza H5N1 virus monovalent vaccines exhibit broad cross-clade immunogenicity, a desired feature for vaccine stockpiling not yet demonstrated by unadjuvanted vaccines. In case of an impending H5N1 virus pandemic, stockpiled OWEA influenza H5N1 virus monovalent vaccines may allow population priming that could slow down the course of pandemic and could offer additional time needed for development of an effective strain specific vaccine supply. PMID: 28483200 [PubMed - as supplied by publisher]
Source: Vaccine - May 5, 2017 Category: Allergy & Immunology Authors: Chada KE, Forshee R, Golding H, Anderson S, Yang H Tags: Vaccine Source Type: research

Cost-effectiveness analysis of vaccinations and decision makings on vaccination programmes in Hong Kong: A systematic review.
CONCLUSIONS: There was a paucity of cost-effectiveness models evaluating vaccination targeted to the Hong Kong population. All evaluated vaccinations and immunisation interventions in Hong Kong, except for Haemophilus influenzae b, hepatitis A and HPV vaccinations, were considered either cost-saving or very cost-effective when compared to status quo. PMID: 28476628 [PubMed - as supplied by publisher]
Source: Vaccine - May 2, 2017 Category: Allergy & Immunology Authors: Wong CKH, Liao Q, Guo VYW, Xin Y, Lam CLK Tags: Vaccine Source Type: research

Haemophilus influenzae oral vaccination for preventing acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease.
CONCLUSIONS: Analyses demonstrate that NTHi oral vaccination of people with recurrent exacerbations of chronic bronchitis or COPD does not yield a significant reduction in the number and severity of exacerbations. Evidence was mixed, and the individual trials that showed a significant benefit of the vaccine are too small to advocate widespread oral vaccination of people with COPD. PMID: 28626902 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - June 19, 2017 Category: General Medicine Authors: Teo E, Lockhart K, Purchuri SN, Pushparajah J, Cripps AW, van Driel ML Tags: Cochrane Database Syst Rev Source Type: research

Definition of healthcare ‐associated influenza: a review and results from an international survey
ConclusionThis work underlined the heterogeneity of HAI definitions in different countries. A standardized definition would be helpful to evaluate HAI spread, outcomes in patients and healthcare systems, and the impact of prevention measures, including vaccination.This article is protected by copyright. All rights reserved.
Source: Influenza and Other Respiratory Viruses - May 1, 2017 Category: Virology Authors: Elodie Munier ‐Marion, Thomas Bénet, Philippe Vanhems Tags: Original Article Source Type: research

PodMed – Week of August 14, 2017
This week’s topics include complications of aortic valve surgery, effectiveness of nasal flu vaccination, testing for Epstein Barr virus and nasopharyngeal cancer, and hepatitis C treatment. Program notes: 0:31 How effective is the flu vaccine? 1:31 Reformulation of nasal type 2:27 Studies to find out why nasal isn’t working 3:12 Epstein Barr virus and nasopharyngeal […]
Source: Johns Hopkins Medicine Weekly Health News - August 11, 2017 Category: Consumer Health News Authors: Elizabeth Tracey Johns Hopkins Medicine Tags: All Podcasts Cancer Heart And Vascular Infectious diseases Influenza (flu) PodMed Surgery Source Type: podcasts

Pattern of exposure to information and its impacts on seasonal influenza vaccination uptake in nurses
Conclusion Current strategy of promotions and campaigns for seasonal influenza vaccination in HCWs may not be effective in increasing vaccination coverage. Measures targeting information-seeking behaviors may serve as an alternative approach.
Source: Journal of Hospital Infection - August 12, 2017 Category: Infectious Diseases Source Type: research

Pharmacists' Scope of Practice: Supports for Canadians with Diabetes
Conclusions Canadians with diabetes can expect to receive influenza vaccines and have medications renewed at their pharmacies. Many patients with diabetes qualify for a publicly funded medication review, and some provinces allow pharmacists to order and interpret laboratory results. This expanded scope provides greater opportunities for pharmacists to help support patients with diabetes in conjunction with other health-care team members.
Source: Canadian Journal of Diabetes - October 14, 2017 Category: Endocrinology Source Type: research

Influenza vaccines for preventing acute otitis media in infants and children.
CONCLUSIONS: Influenza vaccine results in a small reduction in AOM. The observed reduction in the use of antibiotics needs to be considered in light of current recommended practices aimed at avoiding antibiotic overuse. Safety data from these trials were limited. The benefits may not justify the use of influenza vaccine without taking into account the vaccine efficacy in reducing influenza and safety data. We judged the quality of the evidence to be low to moderate. Additional research is needed. PMID: 29039160 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - October 17, 2017 Category: General Medicine Authors: Norhayati MN, Ho JJ, Azman MY Tags: Cochrane Database Syst Rev Source Type: research

Influenza A Virus Infection Damages Zebrafish Skeletal Muscle and Exacerbates Disease in Zebrafish Modeling Duchenne Muscular Dystrophy
DISCUSSION Here, we investigated the effects of an infectious disease on skeletal muscle tissue alone and in combination with a genetic muscle disease. We found that human IAV can infect zebrafish muscle fibers and cause fiber damage via loss of sarcolemma integrity and/or loss of ECM adhesion external to the sarcolemma. Additionally, we showed that molecular and cellular markers of inflammation are present in muscle tissue in response to IAV infection. Finally, we showed that an infectious disease in combination with a genetic muscle disease greatly worsens the severity of muscle tissue degeneration. Taken together, our r...
Source: PLOS Currents Muscular Dystrophy - October 25, 2017 Category: Neurology Authors: Clarissa Henry Source Type: research

Bundling' COPD Care
Conclusions: Our study shows there is indeed a benefit of administering the bundle in COPD patients in terms of lung function, symptom improvement, exercise tolerance and excerbations. Hence the concept of a care bundle should be explored.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Krishnan, S., Kulkarni, T., Ghoshal, A., Dhar, R. Tags: Rehabilitation and Chronic Care Source Type: research

Novel effect of methionine enkephalin against influenza A virus infection through inhibiting TLR7-MyD88-TRAF6-NF- κB p65 signaling pathway.
Novel effect of methionine enkephalin against influenza A virus infection through inhibiting TLR7-MyD88-TRAF6-NF-κB p65 signaling pathway. Int Immunopharmacol. 2017 Dec 05;55:38-48 Authors: Tian J, Jiao X, Wang X, Geng J, Wang R, Liu N, Gao X, Griffin N, Shan F Abstract The morbidity and mortality associated with influenza A virus infections, have stimulated the search for novel prophylactic and therapeutic drugs. The purpose of this study was to investigate the prophylactic and therapeutic effect of synthetic methionine enkephalin (MENK) on mice infected by A/PR/8/34 influenza virus (H1N1) in vivo. ...
Source: International Immunopharmacology - December 5, 2017 Category: Allergy & Immunology Authors: Tian J, Jiao X, Wang X, Geng J, Wang R, Liu N, Gao X, Griffin N, Shan F Tags: Int Immunopharmacol Source Type: research

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