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Vaccination: Shingles (Herpes Zoster) Vaccine
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Total 1796 results found since Jan 2013.
Post-licensure zoster vaccine effectiveness against herpes zoster and postherpetic neuralgia in older adults: a systematic review and meta-analysis
This study is registered on PROSPERO, CRD42021232383.FINDINGS: Our search identified 1240 studies, of which 1162 were excluded based on title and abstract screening. A further 56 articles were excluded on reading the full text. 22 studies (21 cohort studies and one case-control study, involving 9 536 086 participants and 3·35 million person-years in the USA, UK, Canada, and Sweden) were included in the quantitative analysis. Of these, 13 articles were included in the meta-analysis. The overall quality of evidence was very low for all outcomes. The pooled vaccine effectiveness for ZVL against herpes zoster in adults was 45...
Source: Herpes - September 13, 2022 Category: Infectious Diseases Authors: James F Mbinta Binh P Nguyen Prosper Mandela A Awuni Janine Paynter Colin R Simpson Source Type: research
Herpes zoster vaccination efficacy in the long-term care facility population: a qualitative systematic review.
CONCLUSIONS: The studies reviewed showed efficacy of the HZ vaccine in relevant elderly populations residing either in LTCF or in the community including those of advanced age with multiple comorbidities. Consideration can be given to the use of HZ vaccine for individuals over 60 in LTCF, as well as in the community.
PMID: 30913912 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - March 29, 2019 Category: Research Tags: Curr Med Res Opin Source Type: research
Adult Vaccination as a Protective Factor for Dementia: A Meta-Analysis and Systematic Review of Population-Based Observational Studies
CONCLUSION: Routine adult vaccinations are associated with a significant reduction in dementia risk and may be an effective strategy for dementia prevention. Further research is needed to elucidate the causal effects of this association and the underlying mechanisms.PMID:35592323 | PMC:PMC9110786 | DOI:10.3389/fimmu.2022.872542
Source: Herpes - May 20, 2022 Category: Infectious Diseases Authors: Xinhui Wu Haixia Yang Sixian He Ting Xia Diang Chen Yexin Zhou Jin Liu MengSi Liu Zhen Sun Source Type: research
Varicella-Zoster virus reactivation following severe acute respiratory syndrome coronavirus 2 vaccination or infection: New insights
CONCLUSION: This study indicates that the occurrence of VZV reactivation is clinically relevant. However, our findings suggest that COVID-19 vaccination is safe, and remains strongly recommended.PMID:35931613 | PMC:PMC9340059 | DOI:10.1016/j.ejim.2022.07.022
Source: European Journal of Internal Medicine - August 5, 2022 Category: Internal Medicine Authors: Raquel Martinez-Reviejo Sofia Tejada Ganiyat A R Adebanjo Camilla Chello Miriam C Machado Francesca R Parisella Magda Campins Antonella Tammaro Jordi Rello Source Type: research
Biological drugs for systemic lupus erythematosus or active lupus nephritis and rates of infectious complications. Evidence from large clinical trials
Front Immunol. 2022 Sep 23;13:999704. doi: 10.3389/fimmu.2022.999704. eCollection 2022.ABSTRACTSystemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that frequently affects the kidneys, known as lupus nephritis (LN). Such patients are treated with antimalarials, corticosteroids or immunosuppressive drugs, and more recently, target-specific biological drugs. Although efficacy of these therapies improved SLE-related outcomes, SLE remains associated with higher rates of infections. Here, we performed a comprehensive systemic review of infectious complications in clinical trials covering drug interventions f...
Source: Herpes - October 10, 2022 Category: Infectious Diseases Authors: Stefanie Steiger Louisa Ehreiser Juliane Anders Hans-Joachim Anders Source Type: research
Efficacy, effectiveness, and safety of herpes zoster vaccine in the immunocompetent and immunocompromised subjects: A systematic review and network meta-analysis
CONCLUSIONS: Both RZV and ZVL can reduce the risk of herpes zoster in both immunocompetent and immunocompromised subjects. RZV was well-tolerated in the study population and demonstrated stronger protection than ZVL.SYSTEMATIC REVIEW REGISTRATION: Prospero CRD42022310495.PMID:36248796 | PMC:PMC9561817 | DOI:10.3389/fimmu.2022.978203
Source: Herpes - October 17, 2022 Category: Infectious Diseases Authors: Yue Xia Xue Zhang Liuren Zhang Chuanxi Fu Source Type: research
Viral Infection in Middle Age Correlates with Later Dementia Risk
A range of evidence suggests that persistent viral infection contributes to the risk of suffering neurodegenerative conditions such as Alzheimer's disease. This may be due to mechanisms relating to amyloid-β accumulation, in its role as an anti-microbial peptide, a part of the innate immune system. It may have more to do with lasting chronic inflammation subsequent to infection. Researchers here note another addition to the epidemiological data on this topic, in this case linking severe infections requiring hospitalization with later dementia risk. The effect sizes here are large and last for a long time following infecti...
Source: Fight Aging! - February 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Pediatric herpes zoster ophthalmicus: a systematic review
CONCLUSION: HZO occurs in both healthy and immunocompromised children. Recognizing this treatable condition is essential for reducing ocular and systemic morbidity. Long-term follow-up and assessments of the impact on health in adulthood are lacking. More systematic study is needed to determine the incidence of HZO in children and appropriate diagnostic and treatment protocols for the care of pediatric patients with HZO.PMID:36949170 | PMC:PMC10033303 | DOI:10.1007/s00417-023-06033-0
Source: Herpes - March 23, 2023 Category: Infectious Diseases Authors: Farida E Hakim Kamran Riaz Asim Farooq Source Type: research
