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Therapy: Corticosteroid Therapy

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Total 19737 results found since Jan 2013.

A Long-term Persistent Vascular Fluorodeoxyglucose Uptake in a Patient with Large-vessel Vasculitis
Intern Med. 2021 Jul 30. doi: 10.2169/internalmedicine.7772-21. Online ahead of print.ABSTRACTWe herein report a case of large-vessel vasculitis in a 57-year-old woman who developed an intermittent fever and weight loss. While contrast-enhanced computed tomography was noncontributory, positron emission tomography-computed tomography (PET-CT) revealed the diffuse, intense uptake of fluorodeoxyglucose (FDG) in the aorta and its branches. Although she had no signs of relapse after successful oral corticosteroid therapy, PET-CT at 30 months revealed a persistent FDG uptake in the large vessels, which warranted regular follow-u...
Source: Internal Medicine - August 2, 2021 Category: Internal Medicine Authors: Kenya Ie Tsubasa Sakai Eri Kurosu Iori Motohashi Kunihiro Yagihashi Chiaki Okuse Takahide Matsuda Source Type: research

Cancers, Vol. 14, Pages 4610: Adrenal Insufficiency with Anticancer Tyrosine Kinase Inhibitors Targeting Vascular Endothelial Growth Factor Receptor: Analysis of the FDA Adverse Event Reporting System
Conclusions: We call pharmacologists, internists, oncologists and endocrinologists to raise awareness of serious AI with VEGFR-TKIs, and to develop dedicated guidelines, especially for combination regimens with immunotherapy.
Source: Cancers - September 22, 2022 Category: Cancer & Oncology Authors: Emanuel Raschi Michele Fusaroli Valentina Giunchi Andrea Repaci Carla Pelusi Veronica Mollica Francesco Massari Andrea Ardizzoni Elisabetta Poluzzi Uberto Pagotto Guido Di Dalmazi Tags: Article Source Type: research

The role of vascular density in pulmonary rehabilitation of PASC patients
Conclusion: Vascular density endpoints as BV5% can be considered as identifier for selection of patient for a PRP in long-COVID, and potentially other pathologies. Once normalized, patients can safely enroll in a PRP.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Ides, K., Dierckx, W., De Meyer, Y., Lauwers, E., Lanclus, M., De Backer, J., De Backer, W. Tags: 01.02 - Rehabilitation and chronic care Source Type: research

Brazilian guidelines for the treatment of outpatients with suspected or confirmed COVID-19. A joint guideline of the Brazilian Association of Emergency Medicine (ABRAMEDE), Brazilian Medical Association (AMB), Brazilian Society of Angiology and Vascular Surgery (SBACV), Brazilian Society of Geriatrics and Gerontology (SBGG), Brazilian Society of Infectious Diseases (SBI), Brazilian Society of Family and Community Medicine (SBFMC), and Brazilian Thoracic Society (SBPT)
CONCLUSION: To date, few therapies have demonstrated effectiveness in the treatment of outpatients with COVID-19. Recommendations are restricted to what should not be used, in order to provide the best treatment according to the principles of evidence-based medicine and to promote resource savings by aboiding ineffective treatments.PMID:35341739 | PMC:PMC8926872 | DOI:10.1016/j.bjid.2022.102347
Source: Braz J Infect Dis - March 28, 2022 Category: Infectious Diseases Authors: Maicon Falavigna Karlyse Claudino Belli Alexandre Naime Barbosa Alexandre Prehn Zavascki Ana Catharina de Seixas Santos Nastri Christiane Machado Santana Cinara Stein D ébora Dalmas Gräf Flavio Adsuara Cadegiani H élio Penna Guimarães Jos é Tadeu Mon Source Type: research

Adjunctive Dexamethasone Infusion into the Adventitia of the Femoro-popliteal Artery to Enhance Clinical Efficacy Following Endovascular Revascularization: A Proof of Concept First in Man Study
Restenosis following peripheral intervention is in part an inflammatory disease. We hypothesize that a non-stent-based local drug delivery of the anti-inflammatory corticosteroid dexamethasone (DEX) would mitigate intervention-associated inflammation and thus improve long-term arterial patency.
Source: Journal of Vascular Surgery - July 27, 2013 Category: Surgery Authors: Christopher D. Owens, Warren Gasper, Hugh F. Alley, Karen C. Chong, Joseph H. Rapp, Michael S. Conte, Kirk Seward, Marlene S. Grenon Tags: Abstracts from the 2013 Western Vascular Society Annual Meeting Source Type: research

What Is the Right Dose of Systemic Corticosteroids for Intensive Care Unit Patients with Chronic Obstructive Pulmonary Disease Exacerbations?. A Question in Search of a Definitive Answer.
PMID: 24787061 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - May 1, 2014 Category: Respiratory Medicine Authors: Abroug F, Krishnan JA Tags: Am J Respir Crit Care Med Source Type: research

Safety and Efficacy of Dexamethasone Intravitreal Implant (Ozurdex) for the Treatment of Persistent Macular Edema Secondary to Retinal Vein Occlusion in Eyes Previously Treated with Anti-Vascular Endothelial Growth Factors.
Conclusions: Provided the complexity of molecular mechanisms involved in ΜΕ development and the effect of corticosteroids on many of these mechanisms, in our case series, Ozurdex appeared to be a safe and beneficial treatment option for persistent ME due to RVO, in patients with poor or complete lack of response after at least 3 consecutive monthly intravitreal anti-VEGF injections. The complication rate of cataract reported in our study is relatively high compared to previous reports. This might be attributed to the multiple injections, as the incidence of cataract increases with time. Regarding IOP elevation, there is ...
Source: Current Drug Safety - August 5, 2014 Category: Drugs & Pharmacology Authors: Tservakis I, Koutsandrea C, Papaconstantinou D, Paraskevopoulos T, Georgalas I Tags: Curr Drug Saf Source Type: research

Effects of a single course versus repeated courses of antenatal corticosteroids on fetal growth, placental morphometry and the differential regulation of vascular endothelial growth factor
ConclusionRepeated antenatal courses of DEX compromised fetal and placental growth compared with a single course of DEX, and these effects were potentially mediated by altered maternal plasma levels and placental expression of VEGF with consequent decrease in placental vascularization. Because of continuing uncertainties, several key messages for clinicians are provided.
Source: Journal of Obstetrics and Gynaecology Research - August 28, 2014 Category: OBGYN Authors: Amr K. Elfayomy, Shaima M. Almasry Tags: Original Article Source Type: research

Retroperitoneal fibrosis
(RPF) is a rare disease that is marked by systemic inflammation and the development of a periaortic fibroinflammatory mass. The fibroinflammatory infiltration can encase the abdominal aorta, ureters, and other abdominal organs. The clinical presentation often includes constitutional symptoms, abdominal pain, and signs of renal insufficiency or renal failure related to ureteral obstruction. Less frequently, RPF may present with vascular complications, such as venous thrombosis or claudication. The idiopathic form of RPF is most common but secondary forms have been described and are associated with malignancy and a variety ...
Source: Vascular Medicine recent issues - October 10, 2014 Category: Internal Medicine Authors: Tzou, M., Gazeley, D. J., Mason, P. J. Tags: Reviews Source Type: research

Mutual amplification of corticosteroids and angiotensin systems in human vascular smooth muscle cells and carotid atheroma
Abstract The involvement of the renin-angiotensin-aldosterone system (RAAS) and cortisol in increased cardiovascular risk is well known. If numerous relationships between RAAS and corticosteroids have been described, their interactions within the arterial wall, especially during the transdifferentiation of vascular smooth muscle cells (VSMCs) and the atheroma formation, are not established. Here, we clarified the relationships between mRNA levels of corticosteroid and angiotensin system components using cortisol, fludrocortisone, and angiotensin II treatments of cultured VSMCs maintained in a contractile phenoty...
Source: Journal of Molecular Medicine - October 22, 2014 Category: Molecular Biology Source Type: research

Glenohumeral Corticosteroid Injections in Adhesive Capsulitis: A Systematic Search and Review
To assess the literature on outcomes of corticosteroid injections for adhesive capsulitis, and, in particular, image-guided corticosteroid injections.
Source: PM and R - July 1, 2014 Category: Rehabilitation Authors: Amos Song, Laurence D. Higgins, Joel Newman, Nitin B. Jain Tags: Analytical Review: Systematic Search Source Type: research

Antiangiogenic effect of silicate nanoparticles on corneal neo-vascularisation induced by vascular endothelial growth factor
Publication date: January 2014 Source:Journal of Medical Hypotheses and Ideas, Volume 8, Issue 1 Author(s): Mehrdad Mohammadpour , Mahmoud Jabbarvand , Elham Delrish , Ahad Khoshzaban Corneal neo-vascularisation (NV) is a major sight-threatening condition and is caused by infections, degenerative disorders, inflammation and long-time contact lens wear. Corneal NV occurs when the balance between angiogenic and antiangiogenic factors is tipped towards angiogenic molecules. The abnormal vessels may decrease corneal clarity and vision, lead to inflammation and corneal scarring and worsen the prognosis of penetrating keratopl...
Source: Journal of Medical Hypotheses and Ideas - November 3, 2014 Category: Research Source Type: research

Glenohumeral Corticosteroid Injections in Adhesive Capsulitis: A Systematic Search and Review
Conclusions Corticosteroid injections offer rapid pain relief in the short-term (particularly in the first 6 weeks) for adhesive capsulitis. Long-term outcomes seem to be similar to other treatments, including placebo. The added benefit of image-guided corticosteroid injections in improving shoulder outcomes needs further assessment.
Source: PMandR - January 15, 2015 Category: Rehabilitation Source Type: research