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Vaccination: Influenza Vaccine

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Total 6581 results found since Jan 2013.

Safety of components and platforms of COVID-19 vaccines considered for use in pregnancy: A rapid review
CONCLUSION: This rapid review found no evidence of pregnancy-associated safety concerns of COVID-19 vaccines or of their components or platforms when used in other vaccines. However, the need for further data on several vaccine platforms and components is warranted, given their novelty. Our findings support current WHO guidelines recommending that pregnant persons may consider receiving COVID-19 vaccines, particularly if they are at high risk of exposure or have comorbidities that enhance the risk of severe disease.PMID:34489131 | PMC:PMC8360993 | DOI:10.1016/j.vaccine.2021.08.034
Source: Vaccine - September 7, 2021 Category: Allergy & Immunology Authors: Agust ín Ciapponi Ariel Bardach Agustina Mazzoni Tom ás Alconada Steven A Anderson Fernando J Argento Jamile Ballivian Karin Bok Daniel Comand é Emily Erbelding Erin Goucher Beate Kampmann Ruth Karron Flor M Munoz Mar ía Carolina Palermo Edward P K Pa Source Type: research

The adverse reactions to vaccines practice parameter 10 years on -what have we learned?
CONCLUSION: The risk of reactions to vaccination should be weighed against the risk of suffering a vaccine-preventable disease if the vaccine is withheld. There is no need to ask about egg allergy prior to the administration of influenza vaccines, including on screening forms. In most cases, an allergy to a vaccine constituent is not a contraindication to the vaccine containing it. Patients who have had possible anaphylactic reactions to vaccines should be evaluated by an allergist rather than simply being labeled allergic, because most can go on to receive subsequent doses. Most immediate reactions to COVID-19 vaccines ar...
Source: Annals of Allergy, Asthma and Immunology - February 1, 2022 Category: Allergy & Immunology Authors: John M Kelso Source Type: research

Educational interventions for health professionals managing chronic obstructive pulmonary disease in primary care
CONCLUSIONS: The evidence of efficacy was equivocal for educational interventions for health professionals in primary care on the proportion of COPD diagnoses confirmed with spirometry, the proportion of patients with COPD who participate in pulmonary rehabilitation, and the proportion of patients prescribed guideline-recommended COPD respiratory medications. Educational interventions for health professionals may improve influenza vaccination rates among patients with COPD and patient satisfaction with care. The quality of evidence for most outcomes was low or very low due to heterogeneity and methodological limitations of...
Source: Cochrane Database of Systematic Reviews - May 6, 2022 Category: General Medicine Authors: Amanda J Cross Dennis Thomas Jenifer Liang Michael J Abramson Johnson George Elida Zairina Source Type: research

Adult Vaccination as a Protective Factor for Dementia: A Meta-Analysis and Systematic Review of Population-Based Observational Studies
CONCLUSION: Routine adult vaccinations are associated with a significant reduction in dementia risk and may be an effective strategy for dementia prevention. Further research is needed to elucidate the causal effects of this association and the underlying mechanisms.PMID:35592323 | PMC:PMC9110786 | DOI:10.3389/fimmu.2022.872542
Source: Herpes - May 20, 2022 Category: Infectious Diseases Authors: Xinhui Wu Haixia Yang Sixian He Ting Xia Diang Chen Yexin Zhou Jin Liu MengSi Liu Zhen Sun Source Type: research

Biological drugs for systemic lupus erythematosus or active lupus nephritis and rates of infectious complications. Evidence from large clinical trials
Front Immunol. 2022 Sep 23;13:999704. doi: 10.3389/fimmu.2022.999704. eCollection 2022.ABSTRACTSystemic lupus erythematosus (SLE) is a multisystemic autoimmune disease that frequently affects the kidneys, known as lupus nephritis (LN). Such patients are treated with antimalarials, corticosteroids or immunosuppressive drugs, and more recently, target-specific biological drugs. Although efficacy of these therapies improved SLE-related outcomes, SLE remains associated with higher rates of infections. Here, we performed a comprehensive systemic review of infectious complications in clinical trials covering drug interventions f...
Source: Herpes - October 10, 2022 Category: Infectious Diseases Authors: Stefanie Steiger Louisa Ehreiser Juliane Anders Hans-Joachim Anders Source Type: research

Physical interventions to interrupt or reduce the spread of respiratory viruses
CONCLUSIONS: The high risk of bias in the trials, variation in outcome measurement, and relatively low adherence with the interventions during the studies hampers drawing firm conclusions. There were additional RCTs during the pandemic related to physical interventions but a relative paucity given the importance of the question of masking and its relative effectiveness and the concomitant measures of mask adherence which would be highly relevant to the measurement of effectiveness, especially in the elderly and in young children. There is uncertainty about the effects of face masks. The low to moderate certainty of evidenc...
Source: Cochrane Database of Systematic Reviews - January 30, 2023 Category: General Medicine Authors: Tom Jefferson Liz Dooley Eliana Ferroni Lubna A Al-Ansary Mieke L van Driel Ghada A Bawazeer Mark A Jones Tammy C Hoffmann Justin Clark Elaine M Beller Paul P Glasziou John M Conly Source Type: research

Viral Infection in Middle Age Correlates with Later Dementia Risk
A range of evidence suggests that persistent viral infection contributes to the risk of suffering neurodegenerative conditions such as Alzheimer's disease. This may be due to mechanisms relating to amyloid-β accumulation, in its role as an anti-microbial peptide, a part of the innate immune system. It may have more to do with lasting chronic inflammation subsequent to infection. Researchers here note another addition to the epidemiological data on this topic, in this case linking severe infections requiring hospitalization with later dementia risk. The effect sizes here are large and last for a long time following infecti...
Source: Fight Aging! - February 10, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Eliminating Potential Effects of Other Infections during Selection of Nonhuman Primates for COVID-19 Research
Comp Med. 2023 Jan 4;73(1):45-57. doi: 10.30802/AALAS-CM-21-000086. Online ahead of print.ABSTRACTThe study of nonhuman primates (NHP) can provide significant insights into our understanding numerous infectious agents. The etiological agent of COVID-19, SARS-CoV-2 virus, first emerged in 2019 and has so far been responsible for the deaths of over 4 million people globally. In the frenzied search to understand its pathogenesis and immunology and to find measures for prevention and control of this pandemic disease, NHP, particularly macaques, are the preferred model because they manifest similar clinical signs and immunologi...
Source: Comparative Medicine - February 6, 2023 Category: Zoology Authors: M árcia Cr Andrade B árbara Rp Lemos Larissa M Silva Jerilyn K Pecotte Source Type: research