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Specialty: Neurology
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Total 29834 results found since Jan 2013.
"Growing pains" in children and adolescents as an early symptom of migraine: A prospective study
CONCLUSIONS: Pain in the lower limbs of children and adolescents, commonly referred to as GP by pediatricians and orthopedists, may reflect a precursor or comorbidity with migraine.PMID:37671464 | DOI:10.1111/head.14608
Source: Headache - September 6, 2023 Category: Neurology Authors: Raimundo Pereira Silva-N éto Adriana de Almeida Soares Wallyson Pablo de Oliveira Souza Ana Gabriela Krymchantowski Carla Jevoux Abouch Krymchantowski Source Type: research
Treatment of multisegmental vertebral compression, burst fractures, and sandwich vertebra with severe osteoporosis using the PKP technique: a case report and literature review
This study aimed to present a special case of treatment of a patient with multisegmental vertebral compression fracture, burst fracture, and sandwich vertebra and to review the literature on this condition. An 85 year-old female presented with severe low back pain but no radiating pain in the lower extremities. The patient was diagnosed with T12 and L5 vertebral compression fractures, fresh vertebral burst fractures in L2 and L3, and osteoporosis. The focus was on formulating a surgical treatment strategy. At the 12 month follow-up, no neurological deficits were observed, and the chosen surgical treatment approach yiel...
Source: Frontiers in Neurology - September 6, 2023 Category: Neurology Source Type: research
Comparison of the safety and efficacy of radiofrequency thermocoagulation with percutaneous balloon compression for treating trigeminal neuralgia: a systematic review and meta-analysis
ConclusionIn the treatment of TN, both RFT and PBC can achieve good short-term efficacy, and no significant differences were noted between the outcomes of the two approaches. Compared with RFT, PBC may result in a lower pain score and recurrence rate in the medium and long terms, but it is a higher incidence of cold sores, and the decrease of masticatory muscle strength is more obvious.
Source: Frontiers in Neurology - September 6, 2023 Category: Neurology Source Type: research
Proteomics profiling reveals mitochondrial damage in the thalamus in a mouse model of chronic migraine
ConclusionOur findings highlight the involvement of mitochondrial damage in the thalamus in central sensitization of CM, which provides evidence of possible metabolic mechanisms in migraine pathophysiology.
Source: The Journal of Headache and Pain - September 5, 2023 Category: Neurology Source Type: research
Sleep Symptoms and Disorders in Episodic Migraine: Assessment and Management
AbstractPurpose of ReviewWe review research on sleep symptoms and disorders in patients with episodic migraine and propose a framework for evaluating sleep symptoms in this patient population.Recent FindingsPatients with episodic migraine consistently report poorer sleep on validated self-reports compared to those without migraine. In polysomnographic studies, children with migraine have objectively shorter sleep duration and lower percentage of REM sleep interictally. Prospective actigraphy studies in adults and children suggest that there are no significant changes in sleep duration, efficiency, or quality in the night...
Source: Current Pain and Headache Reports - September 4, 2023 Category: Neurology Source Type: research
Current treatment options for cluster headache: limitations and the unmet need for better and specific treatments —a consensus article
ConclusionWe find that there is a great and unmet need to pursue novel and targeted preventive modalities to suppress the horrific pain attacks for people with cluster headache.Graphical Abstract
Source: The Journal of Headache and Pain - September 4, 2023 Category: Neurology Source Type: research
Impact of five floor coverings on the orthostatic balance of healthy subjects
This study aimed at assessing the impact of five different floor coverings on the orthostatic balance in 48 healthy subjects. Static posturography was performed with eyes open or closed on a platform in a control condition (no covering) and with five different covering surfaces: foam, silicone, ethyl vinyl acetate, and two textured mats with small (height 2 mm) or large pimples (7 mm). The average velocity of center of pressure (CoP) displacement was the primary endpoint measure and ten other posturographic variables were assessed. Comfort and pain produced by the covering were also scored. In eyes open condition, the aver...
Source: Brain Research - September 3, 2023 Category: Neurology Authors: Nathalie Bonardet Jean Chapus Jean-Pascal Lefaucheur Nicolas Lampire Alain Cr éange Marc Sorel Source Type: research
TSLP in DRG neurons causes the development of neuropathic pain through T cells
Peripheral nerve injury to dorsal root ganglion (DRG) neurons develops intractable neuropathic pain via induction of neuroinflammation. However, neuropathic pain is rare in the early life of rodents. Here, we ...
Source: Journal of Neuroinflammation - September 2, 2023 Category: Neurology Authors: Yuka Ino, Motoyo Maruyama, Masumi Shimizu, Rimpei Morita, Atsuhiro Sakamoto, Hidenori Suzuki and Atsushi Sakai Tags: Research Source Type: research
Transcriptome Profiling of miRNA-mRNA Interactions and Associated Mechanisms in Chemotherapy-Induced Neuropathic Pain
AbstractChemotherapy-induced neuropathic pain (CINP) is a dose-limiting adverse event affecting 40% of chemotherapy patients. MiRNA-mRNA interaction plays an important role in various processes. However, detailed profiling of miRNA-mRNA interactions in CINP remains unclear. Here, a rat-based CINP model was established using paclitaxel, followed by nociceptive behavioral tests related to mechanical allodynia, thermal hyperalgesia, and cold allodynia. The landscape of miRNA-mRNA interaction in the spinal dorsal horn was investigated through mRNA transcriptomics and small RNA sequencing. Under CINP condition, 86 differentiall...
Source: Molecular Neurobiology - September 1, 2023 Category: Neurology Source Type: research
Glutamatergic Neurons in the Zona Incerta Modulate Pain and Itch Behaviors in Mice
AbstractEmerging evidence suggest that parvalbumin neurons in zona incerta (ZI) modulate pain and itch behavior in opposite manners. However, the role of ZI glutamatergic neurons, a unique incertal neuronal subpopulation residing in the caudal division, in pain and itch modulation remains unknown. In the present study, by combining chemogenetic manipulation, fiber photometry, and behavioral tests, we proved that incertal glutamatergic neurons served as an endogenous negative diencephalic modulator for both pain and itch processing. We demonstrated that ZI vesicular glutamate transporter 2 (VGluT2) neurons exhibited increas...
Source: Molecular Neurobiology - September 1, 2023 Category: Neurology Source Type: research
Predictors of performance and perceived fatigability in people with multiple sclerosis
CONCLUSIONS: Preliminary findings suggest that self-reported functioning levels, including physical and perceived cognitive function, are potential predictors of performance and perceived fatigability in MS. Notably, perceived fatigue impact showed no association with performance or perceived fatigability. Future studies are warranted to confirm and extend our findings.PMID:37655601 | DOI:10.1080/01616412.2023.2252283
Source: Neurological Research - September 1, 2023 Category: Neurology Authors: Libak Abou Nora E Fritz Anna L Kratz Source Type: research
Safety and efficacy of ubrogepant for the acute treatment of perimenstrual migraine attacks: A post hoc analysis
CONCLUSIONS: Ubrogepant demonstrated similar efficacy for the treatment of pmM and non-pmM attacks. No new safety signals were identified.PMID:37655536 | DOI:10.1111/head.14619
Source: Headache - September 1, 2023 Category: Neurology Authors: E Anne MacGregor Susan Hutchinson Hongxin Lai Brett Dabruzzo Sung Yun Yu Joel M Trugman Jessica Ailani Source Type: research
