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Vaccination: Influenza Vaccine
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Total 6581 results found since Jan 2013.
Race-specific changes in endothelial inflammation and microRNA in response to an acute inflammatory stimulus
This study assessed racial differences in acute induced endothelial inflammation and related miRs. Cultured human umbilical vein endothelial cells (HUVECs) derived from AA and Caucasian Americans (CA) were exposed to the influenza vaccine to determine changes in inflammatory markers, endothelial nitric oxide synthase (eNOS), and miR expression/release. Endothelial function (flow-mediated dilation [FMD]), circulating IL-6, and circulating miR were also measured in young, healthy AA and CA individuals before and after receiving the influenza vaccine. There were no significant racial differences in any parameters at baseline....
Source: American Journal of Physiology. Heart and Circulatory Physiology - May 7, 2021 Category: Physiology Authors: Ryan M Sapp Catalina A Chesney Catherine B Springer Matthew R Laskowski Daniel B Singer Lauren E Eagan Sara E Mascone William S Evans Steven J Prior James M Hagberg Sushant M Ranadive Source Type: research
Impact of pharmacy intervention on influenza vaccination acceptance: a systematic literature review and meta-analysis
Conclusion Pharmacists can play a significant role to improve patient treatment, adherence, and outcomes associated with influenza vaccines. Once pharmacy-based immunization is established, proactive involvement of is key to ensure successful program implementation and results. Expanding access for pharmacists and pharmacy intervention to provide vaccinations may increase vaccination acceptance and could be a valuable intervention in patient care. Additional studies should consider high-risk populations to inform optimal design and implementation strategies.
Source: International Journal of Clinical Pharmacy - May 28, 2021 Category: Drugs & Pharmacology Source Type: research
Methodologic approaches in studies using real-world data (RWD) to measure pediatric safety and effectiveness of vaccines administered to pregnant women: A scoping review
CONCLUSIONS: A body of literature is available from which to plan and design future studies of vaccination in pregnant women using RWD. This is of intense importance as new vaccines, such as those for COVID-19, become available to the general population via approval or authorization without inclusion of pregnant women in the clinical trials.PMID:34090699 | DOI:10.1016/j.vaccine.2021.05.071
Source: Vaccine - June 6, 2021 Category: Allergy & Immunology Authors: Tamar Lasky Ann W McMahon Wei Hua Richard Forshee Source Type: research
Healthcare workers' perceptions and experiences of communicating with people over 50 years of age about vaccination: a qualitative evidence synthesis
CONCLUSIONS: There is little research focusing specifically on healthcare workers' perceptions and experiences of communication with older adults about vaccination. The studies we identified suggest that healthcare workers differed among themselves in their perceptions about the aim of this communication and about the role of older adults in vaccine decisions. Based on these findings and the other findings in our review, we have developed a set of questions or prompts that may help health system planners or programme managers when planning or implementing strategies for vaccination communication between healthcare workers ...
Source: Cochrane Database of Systematic Reviews - July 20, 2021 Category: General Medicine Authors: Claire Glenton Benedicte Carlsen Simon Lewin Manuela Dominique Wennekes Brita Askeland Winje Renske Eilers VITAL consortium Source Type: research
Hexavalent vaccines: What can we learn from head-to-head studies?
CONCLUSION: Although the licensed hexavalent vaccines are generally considered similar, analyses of immunogenicity data from head-to-head trials highlighted differences that could be related to differences in composition and formulation. In addition, the demonstrated non-inferiority of the immunogenicity of the more recent vaccines versus DT3aP-HBV-IPV/Hib does not allow a full bridging to similar efficacy, effectiveness and safety. The availability of DT3aP-HBV-IPV/Hib over > 20 years allowed to collect a wealth of data on its long-term immunogenicity, safety and effectiveness in clinical and post-marketing studies, an...
Source: Vaccine - September 17, 2021 Category: Allergy & Immunology Authors: Markus Knuf Herv é Haas Pilar Garcia-Corbeira Elisa Turriani Piyali Mukherjee Winnie Janssens Val érie Berlaimont Source Type: research
The burden of seasonal influenza-associated complications in Italy: a systematic review
ConclusionsAlthough there are still gaps in existing data, there is evidence of the significant burden that influenza places each year especially on high-risk groups. Summaries of the available data may inform decision-making in regard to vaccine strategies and public health policies.Key messagesExisting data show evidence of significant burden of influenza on Italian population, especially on high-risk groups.Summaries of country-specific influenza-related burden are crucial in informing vaccine strategies.
Source: The European Journal of Public Health - October 20, 2021 Category: General Medicine Source Type: research
A systematic literature review on the use of health care resources during pandemic response
ConclusionsTo be better prepared and to be able to respond fast to a pandemic outbreak, it is important to have insight in the availability of pandemic resources on a national and regional level, their use and mutual dependencies. This makes it possible to anticipate on fast changes and possible shortages by reallocating resources within and between regions.
Source: The European Journal of Public Health - October 20, 2021 Category: General Medicine Source Type: research
Immunosuppression and immunization: Vaccination in pediatric patients with neuromuscular diseases treated with steroids or immune-modulating drugs
CONCLUSION: With just a few exceptions, vaccines are safe in this group of patients and they should receive the same immunizations and according to the same schedule, as all children. Live vaccines should not be administered in patients receiving high dose steroid or immune-modulating drugs such as anti-B cell treatments (rituximab), high dose methotrexate, azathioprine or 6-mercaptopurine. Whenever possible, all live vaccines should be administered prior to long term immune-suppressant treatments. Additional vaccines are recommended in this risk population of children (influenza, pneumococcal, varicella).PMID:34752936 | D...
Source: European Journal of Paediatric Neurology - November 9, 2021 Category: Neurology Authors: Tanja Golli Andrej Kastrin Marko Pokorn Zvonka Rener-Primec Source Type: research
Viral agents and systemic levels of inflammatory cytokines in vulnerable and stable atherosclerotic carotid plaques
CONCLUSION: The EBV genome was found in the "core" of two vulnerable carotid plaques, but not in their respective adjacent control. Influenza vaccination was associated with a lower incidence of carotid plaque vulnerability. Serum levels of TNF-α and IL-6 were higher in patients with a vulnerable plaque compared to patients with a stable plaque.PMID:34902464 | DOI:10.1016/j.avsg.2021.10.070
Source: Herpes - December 13, 2021 Category: Infectious Diseases Authors: Daniela Mazzaccaro Maria Dolci Federica Perego Serena Delbue Matteo Giannetta Rosanna Cardani Laura Valentina Renna Elena Costa Massimiliano M Corsi-Romanelli Cristina Galli Elena Pariani Giovanni Nano Claudio Clemente Nicoletta Basilico Source Type: research
Vaccination in pediatric acquired inflammatory immune-mediated neuromuscular disorders
CONCLUSION: s: There are no strong evidence supporting relationship between vaccination with different pediatric vaccines and development of first episodes or reccurrences of GBS, Bell's palsy, optic neuritis (ON), juvenile MG, CIDP, and IM. The vaccination and revaccination with inactivated vaccines is considered safe in children with medical history of GBS, Bell's palsy, ON, MG and IM. Caution when immunization against influenza, quadrivalent conjugated meningococcal vaccine (MCV4) and pneumococcal disease and avoiding tetanus toxoid immunization in CIDP patients is suggested. Patients with immune mediated acquired NMD s...
Source: European Journal of Paediatric Neurology - January 8, 2022 Category: Neurology Authors: Nina Bari ši? Daniel Turudi ? Lorna Stemberger Mari ? Goran Te šovi? Source Type: research
Movement disorders, cerebral palsy and vaccination
Eur J Paediatr Neurol. 2021 Dec 21;36:143-150. doi: 10.1016/j.ejpn.2021.12.006. Online ahead of print.ABSTRACTThis review focused on vaccination in children with movement disorders, including cerebral palsy and the movement disorders triggered by vaccination in children with and without neurological disabilities. The following clinical questions were addressed: 1) Can children with movement disorders be vaccinated? 2) Can vaccination trigger movement disorders in children without neurological disabilities? 3) Can vaccination trigger movement disorders in children with neurological disabilities? and 4) Is there any consensu...
Source: European Journal of Paediatric Neurology - January 3, 2022 Category: Neurology Authors: Zuzana Liba Josef Kraus Tomas Necas Jiri Necas Miloslav Klugar Pavel Krsek Source Type: research
The adverse reactions to vaccines practice parameter 10 years on -what have we learned?
CONCLUSION: The risk of reactions to vaccination should be weighed against the risk of suffering a vaccine-preventable disease if the vaccine is withheld. There is no need to ask about egg allergy prior to the administration of influenza vaccines, including on screening forms. In most cases, an allergy to a vaccine constituent is not a contraindication to the vaccine containing it. Patients who have had possible anaphylactic reactions to vaccines should be evaluated by an allergist rather than simply being labeled allergic, because most can go on to receive subsequent doses. Most immediate reactions to COVID-19 vaccines ar...
Source: Annals of Allergy, Asthma and Immunology - February 1, 2022 Category: Allergy & Immunology Authors: John M Kelso Source Type: research
COVID-19 and pregnancy: clinical outcomes and scientific evidence about vaccination
Eur Rev Med Pharmacol Sci. 2022 Apr;26(7):2610-2626. doi: 10.26355/eurrev_202204_28499.ABSTRACTPregnant women and their infants are at high risk to develop a severe COVID-19, with increased rates of hospitalisation to intensive care units, need for mechanical ventilation and mortality. Preterm birth, fetal vascular malperfusion, and premature rupture of membrane have been the most reported adverse pregnancy outcomes and these effects have been especially associated with the onset of the disease at early gestational age. The early expression of ACE2 and TMPRSS2 in human embryos has been proven, determining an increased susc...
Source: Pharmacological Reviews - April 20, 2022 Category: Drugs & Pharmacology Authors: A Facciol à C Micali G Visalli E Venanzi Rullo Y Russotto P Lagan à A Lagan à G Nunnari A Di Pietro Source Type: research
