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Seropositive Neuromyelitis Optica in a Case of Undiagnosed Ankylosing Spondylitis: A Neuro-Rheumatological Conundrum
In this study, a 35-year-old Indian man with an undiagnosed progressive axial spondyloarthropathy (i.e., AS) is reported presenting with acute-onset longitudinally extensive transverse myelitis, a clinical subset of NMOSD. Neuromyelitis optica spectrum disorder (NMOSD), a primary demyelinating disorder of the central nervous system (CNS), is an autoimmune astrocytopathy against foot processes of aquaporin-4 (AQP4) water channels, which manifests with optic neuritis, longitudinally extensive transverse myelitis (LETM), area-postrema syndrome, brainstem syndrome diencephalic syndrome, and cerebral syndrome.1-4 Ankylosing spo...
Source: Herpes - July 22, 2022 Category: Infectious Diseases Authors: Ritwik Ghosh Md Devlina Roy Mois és León-Ruiz Shambaditya Das Souvik Dubey Juli án Benito-León Source Type: research

Dermatomyositis Following BNT162b2 mRNA COVID-19 Vaccination
J Korean Med Sci. 2022 Feb 7;37(5):e32. doi: 10.3346/jkms.2022.37.e32.ABSTRACTDermatomyositis (DM) is one of the uncommon multi-organ idiopathic inflammatory myopathies that has been reported following the hepatitis B, Influenza, tetanus toxoid, H1N1, and BCG vaccines. However, an association with the coronavirus disease 2019 (COVID-19) vaccine is yet to be reported. In this case, we present the case of a 43-year-old Asian Indian female who was diagnosed with DM 10 days after receiving the second dosage of BNT162b2 mRNA COVID-19 vaccination, in the absence of any additional triggering factors. The diagnosis was established...
Source: J Korean Med Sci - February 8, 2022 Category: General Medicine Authors: Wesam Gouda Anwar Albasri Faisal Alsaqabi Humoud Y Al Sabah Marwan Alkandari Hassan Abdelnaby Source Type: research

Zika Virus Potentiates the Development of Neurological Defects and Microcephaly: Challenges and Control Strategies
Conclusions Apart West Nile virus (78), thousands of congenital microcephaly cases, fetal brain tissue damage and neurological syndromes have been associated with ZIKV infection. Unfortunately, the epidemics of this mosquito born, and a relative stable virus is on a rise. Although congenital microcephaly is a rare disorder however, due to lack of standardized diagnostic test facilities, the incidence in the geographically widespread ZIKV epidemic regions is higher. Animals studies showed that ZIKV is a neurotropic virus. It directly targets the developing embryonic brain cells by inducing apoptosis, cell-cycle arrest, and...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research