Acanthosis NigricansThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you your search results in order of date.

Pages: 1 2 3

101 records returned

The clinical and metabolic features of Irish patients with acanthosis nigricansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Acanthosis nigricans in Irish subjects is associated with severe obesity and insulin resistance. The analysis highlights that subjects with acanthosis nigricans should be screened for insulin resistance and its complications. Content Type Journal ArticleCategory Poster PresentationsDOI 10.1007/BF03170260Authors S. McQuaid, St James’s Hospital Metabolic Research Unit, Department of Endocrinology Dublin IrelandY. Rahman, St James’s Hospital Metabolic Research Unit, Department of Endocrinology Dublin IrelandO. Yousif, St James’s Hospital Metabolic Research Unit, Department of Endocrinology Du...
Source: Irish Journal of Medical Science - November 17, 2009 Category: Journals (General) Tags: Irish Journal of Medical Science Source Type: journals

Insulin Resistance Linked to Acanthosis NigricansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
SAN FRANCISCO — Insulin resistance may be present in patients with acanthosis nigricans, particularly if they are overweight or obese, and research increasingly supports a link between these conditions. (Source: Skin and Allergy News)
Source: Skin and Allergy News - November 1, 2009 Category: Dermatology Authors: DAMIAN McNAMARA Tags: Across Specialties Source Type: journals

[Fatty liver disease, insulin resistance and adiponectin in an obese pediatric population.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Obesity and RI are risk factors for liver steatosis in children and adolescents. Decreased serum adiponectin is closely and independently associated with steatosis. PMID: 19850541 [PubMed - as supplied by publisher] (Source: Anales de Pediatria)
Source: Anales de Pediatria - October 19, 2009 Category: Pediatrics Authors: López-Capapé M, López-Bermejo A, Alonso Blanco M, Lara Orejas E, Corbatón Blasco J, Barrio Castellanos R Tags: An Pediatr (Barc) Source Type: journals

Young people with acanthosis nigricans are at high risk for Type 2 diabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Study results show that young people with acanthosis nigricans are at increased risk for abnormal glucose metabolism, high blood pressure, and low high-density lipoprotein cholesterol. (Source: MedWire News - Diabetes)
Source: MedWire News - Diabetes - October 19, 2009 Category: Endocrinology Source Type: news

Hypodontia in Beare-Stevenson Syndrome: An Example of Dental Anomalies in FGFR-related Craniosynostosis Syndromes.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a new case of Beare-Stevenson syndrome characterized by cutis gyrata, craniosynostosis, acanthosis nigricans, ear defects, a prominent umbilical stump and midface hypoplasia. He had dental findings of natal teeth and hypodontia of the primary and permanent teeth. This is the second patient with BSS syndrome to be reported with hypodontia and natal teeth; the first patient was described by Beare in 1969. We review the current literature to investigate the relation between dental anomalies and FGFR-related mutations in Beare-Stevenson syndrome and other craniosynostosis syndromes such as Apert, Crouzon and Pfeiffer...
Source: The Cleft Palate-Craniofacial Journal - October 19, 2009 Category: ENT & OMF Authors: Tao YC, Slavotinek A, Vargervik K, Oberoi S Tags: Cleft Palate Craniofac J Source Type: journals

Acanthosis nigricans identifies young people at high metabolic riskEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Presence of acanthosis nigricans identifies a population of young people at high-risk for abnormal glucose homeostasis, high blood pressure, and low high-density lipoprotein cholesterol, report researchers. (Source: MedWire News - Dermatology)
Source: MedWire News - Dermatology - October 9, 2009 Category: Dermatology Source Type: news

Prevalence of acanthosis nigricans and its correlates in a cross-section of Nigerians with type 2 diabetes mellitus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report bridges the information gap and documents the prevalence of AN in Nigerians with type 2 DM as well as its clinical correlates. Three hundred and forty consecutive subjects with type 2 DM were examined for the presence of AN and its associated clinical features. The prevalence of AN in type 2 DM in this report is 17%. Factors associated with AN include obesity, a family history of DM, female gender, the presence of hypertension and poor glycaemic control. PMID: 19762579 [PubMed - in process] (Source: Tropical Doctor)
Source: Tropical Doctor - September 20, 2009 Category: Tropical Medicine Authors: Ogbera AO, Akinlade A, Ajose O, Awobusuyi J Tags: Trop Doct Source Type: journals

[Skin manifestations, treatment and rehabilitation in overweight and obesity.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Overweight and obesity is a public health problem in Hungary and in the Western world. It is important to underline that obesity is an illness and an important risk factor for several skin and other diseases. An overview of skin diseases caused or aggravated by obesity (acanthosis nigricans, acrochordons, keratosis pilaris, hyperandrogenism, stria, adiposis dolorosa, lymphoedema, chronic venous insufficiency, plantar hyperkeratosis, lipoedema, skin infections, acne inversa, psoriasis, tophi) helps us to look and see as well. Look for the possibility of skin infections as it helps the early diagnosis and to avoid compli...
Source: Orvosi Hetilap - September 4, 2009 Category: Journals (General) Authors: Wenczl E Tags: Orv Hetil Source Type: journals

Malignant acanthosis nigricans with enhanced expression of fibroblast growth factor receptor 3.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19688170 [PubMed - in process] (Source: Acta Derm Venereol A...)
Source: Acta Derm Venereol A... - August 20, 2009 Category: Dermatology Authors: Hida Y, Kubo Y, Nishio Y, Murakami S, Fukumoto D, Sayama K, Hashimoto K, Arase S Tags: Acta Derm Venereol Source Type: journals

Lipodystrophy: an unusual diagnosis in a case of oligomenorrhea and hirsutism.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION:: Familial partial lipodystrophy, Dunnigan variety, can present with features similar to polycystic ovary syndrome. Diagnosis is critical because the metabolic complications of the disorder have significant morbidity. PMID: 19622949 [PubMed - in process] (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - July 24, 2009 Category: OBGYN Authors: Keller J, Subramanyam L, Simha V, Gustofson R, Minjarez D, Garg A Tags: Obstet Gynecol Source Type: journals

Juvenile generalized acanthosis nigricans without any systemic diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Pediatrics International)
Source: Pediatrics International - July 22, 2009 Category: Pediatrics Authors: Müzeyyen Gönül, Arzu Kılıç, Seray K. Çakmak, Ülker Gül, Özlem D. Ekiz, Gülüşan Ergül Tags: PATIENT REPORTS Source Type: journals

Acanthosis Nigricans and Insulin Sensitivity in patients with Achondroplasia and Hypochodroplasia due to FGFR3 mutations.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Our findings suggest that the development of AN in patients with ACH/HCH is not due to insulin insensitivity either on its own or secondary to treatment with rhGH. Whether the acanthosis nigricans is due to altered melanocyte function in these individuals remains to be established. PMID: 19622626 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - July 20, 2009 Category: Endocrinology Authors: Alatzoglou KS, Hindmarsh PC, Brain C, Torpiano J, Dattani MT Tags: J Clin Endocrinol Metab Source Type: journals

Type B insulin resistance in a systemic lupus erythematosus patientEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes a case wherein the patient had presented with uncontrolled diabetes and required > 3000 units of human insulin to control hyperglycemia. She also had features of SLE. There was complete recovery following treatment with steroids. (Source: APLAR Journal of Rheumatology)
Source: APLAR Journal of Rheumatology - July 15, 2009 Category: Rheumatology Authors: Vikas OSTWAL, Jyotsna OAK Tags: Case reports Source Type: journals

Malignant acanthosis nigricans with esophageal cancerEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract A 62-year-old woman was referred to our hospital with presenting pigmentation and/or dermal thickening in the nucha, face, axilla, abdomen, and hands. She also presented a history of weight loss of 4 kg during the previous 3 months. She was pathologically diagnosed as having acanthosis nigricans by skin biopsy. She subsequently underwent 18F-FDG-PET, CT, and upper gastrointestinal endoscopy, and then was diagnosed as having malignant acanthosis nigricans with squamous cell carcinoma in the esophagus at the clinical stage of T3, N0, M0, stage IIA in the UICC stage classification. She underwent subtot...
Source: Esophagus - June 17, 2009 Category: Gastroenterology Tags: Esophagus Source Type: journals

[Genetics] A truncation mutation in TBC1D4 in a family with acanthosis nigricans and postprandial hyperinsulinemiaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Tre-2, BUB2, CDC16, 1 domain family member 4 (TBC1D4) (AS160) is a Rab-GTPase activating protein implicated in insulin-stimulated glucose transporter... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - June 9, 2009 Category: Science Authors: Dash, S., Sano, H., Rochford, J. J., Semple, R. K., Yeo, G., Hyden, C. S. S., Soos, M. A., Clark, J., Rodin, A., Langenberg, C., Druet, C., Fawcett, K. A., Tung, Y. C. L., Wareham, N. J., Barroso, I., Lienhard, G. E., O'Rahilly, S., Savage, D. B. Tags: Genetics Source Type: journals

[Miscellanea] Acanthosis nigricansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - May 21, 2009 Category: Pediatrics Authors: Marimuthu, S, Menon, B S Tags: Miscellanea Source Type: journals

Prevalence and risk factors for non-alcoholic fatty liver disease among adults in an urban Sri Lankan populationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: The prevalence of NAFLD among adults in this urban Sri Lankan community is high and is strongly associated with constituent features of the metabolic syndrome. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - May 20, 2009 Category: Gastroenterology Authors: Anuradha S Dassanayake, Anuradhani Kasturiratne, Shaman Rajindrajith, Udaya Kalubowila, Sureka Chakrawarthi, Arjuna P De Silva, Miyuki Makaya, Tetsuya Mizoue, Norihiro Kato, A. Rajitha Wickremasinghe, H. Janaka de Silva Source Type: journals

Hereditary leukonychia totalis, acanthosis-nigricans-like lesions and hair dysplasia: A new syndrome?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report an original observation of hereditary leukonychia totalis in a father and two of his children, associated with acanthosis-nigricans-like lesions and hair dysplasia. These symptoms were also present in eight other members of the same family. PMID: 19401242 [PubMed - as supplied by publisher] (Source: European Journal of Medical Genetics)
Source: European Journal of Medical Genetics - May 3, 2009 Category: Genetics & Stem Cells Authors: Le Corre Y, Steff M, Croue A, Filmon R, Verret JL, Le Clech C Tags: Eur J Med Genet Source Type: journals

Re: “Acanthosis nigricans and an alternative for its surgical therapy”Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
I read with interest the article by Isket et al. describing an alternative surgical therapy for acanthosis nigricans. The authors nicely summarize the multiple variants of acanthosis nigricans, but do not specify which variant their patient had. Their patient's results after surgery appear very good. However, in my judgment, the patient's lesion appeared more consistent with an epidermal nevus rather than acanthosis nigricans. Although the authors note that their patient had received prior therapies (cryotherapy and electrosurgery) and these therapies may have altered the appearance of her condition, her lesions are not t...
Source: Journal of Plastic, Reconstructive & Aesthetic Surgery - April 24, 2009 Category: Cosmetic Surgery Authors: David R. Berk Tags: Correspondence and Communications Source Type: journals

A Newborn with Acanthosis Nigricans: Can It Be Crouzon Syndrome with Acanthosis Nigricans?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a 10-hour-old newborn who presented with bilateral choanal atresia, craniosynostosis and acanthosis nigricans. Molecular tests identified the FGFR3 Ala391Glu substitution confirming the diagnosis of CAN. Of the 35 cases of CAN reported in literature till date, only one child had acanthosis nigricans at birth. This is the first case from India to have been reported with this mutation. (Source: Pediatric Dermatology)
Source: Pediatric Dermatology - April 17, 2009 Category: Dermatology Authors: Sheetal Sharda, Inusha Panigrahi, Kirti Gupta, Sunit Singhi, Rakesh Kumar Source Type: journals

Gastric diffuse large B-cell lymphoma (DLBCL) exhibiting oral acanthosis nigricans and tripe palmsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Approximately one-third of non-Hodgkin lymphomas arise primarily from sites other than lymph nodes, such as spleen or bone marrow, and even from sites which normally contain no native lymphoid tissue. The extranodal lymphomas represent a challenge in routine lymphoma diagnosis, due to the variety of histological types, molecular abnormalities and clinical pictures . Diffuse large B-cell lymphoma (DLBCL) is the most common extranodal lymphoma encountered in the gastrointestinal tract. This is mainly a disease of older adults in the seventh decade, even though it may occasionally affect children and young adults. It typicall...
Source: Digestive and Liver Disease - April 5, 2009 Category: Gastroenterology Authors: M.D. Mignogna, G. Fortuna, J. Falleti, S. Leuci Tags: Correspondence Source Type: journals

Paraneoplastic sensory neuropathy associated with small cell carcinoma of the gallbladderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on what appears to be the first case of a patient, a 48-year-old woman, with anti-Hu paraneoplastic sensory neuropathy and small cell carcinoma of the gallbladder. The patient's neurologic symptoms preceded the diagnosis of small cell carcinoma by 11 months. These symptoms improved after surgical removal of the tumor and chemotherapy. The small cell carcinoma was relatively small and was not associated with gallstones. In spite of the small size of the tumor, it metastasized to a celiac lymph node and probably to the liver. Anti-Hu paraneoplastic sensory neuropathy should be added to the list of paraneoplastic sy...
Source: Annals of Diagnostic Pathology - April 1, 2009 Category: Pathology Authors: Norma O. Uribe-Uribe, Aura Matilde Jimenez-Garduño, Donald E. Henson, Jorge Albores-Saavedra Tags: Case Reports Source Type: journals

Paraneoplastic sensory neuropathy associated with small cell carcinoma of the gallbladder.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report on what appears to be the first case of a patient, a 48-year-old woman, with anti-Hu paraneoplastic sensory neuropathy and small cell carcinoma of the gallbladder. The patient's neurologic symptoms preceded the diagnosis of small cell carcinoma by 11 months. These symptoms improved after surgical removal of the tumor and chemotherapy. The small cell carcinoma was relatively small and was not associated with gallstones. In spite of the small size of the tumor, it metastasized to a celiac lymph node and probably to the liver. Anti-Hu paraneoplastic sensory neuropathy should be added to the list of paraneoplastic sy...
Source: Annals of Diagnostic Pathology - March 26, 2009 Category: Pathology Authors: Uribe-Uribe NO, Jimenez-Garduño AM, Henson DE, Albores-Saavedra J Tags: Ann Diagn Pathol Source Type: journals

Seborrhoeic keratoses in patients with internal malignancies: a case–control study with prospective accrual of patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion No association was found between seborrhoeic keratoses and cancer. Furthermore, our data did not provide support to the validity of the Leser-Trélat sign in patients with internal malignancies. None declared. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - March 6, 2009 Category: Dermatology Authors: AM Fink, D Filz, G Krajnik, W Jurecka, H Ludwig, A Steiner Source Type: journals

Long-term improvement of metabolic control with pioglitazone in a woman with diabetes mellitus related to Dunnigan syndrome: A case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 54-year-old woman was referred to hospital because of poor metabolic control. Clinical examination revealed marked acanthosis nigricans, and a striking lack of adipose tissue on the limbs, and excess fat deposits on the neck and face. She had been treated for diabetes since 2001 with high doses of insulin along with metformin. Clinical tests showed hypertriglyceridaemia with low high density lipoprotein (HDL) cholesterol, and cholestasis with mild cytolysis. Dunnigan syndrome (familial partial lipodystrophy type 2) was suspected and confirmed by molecular genetics. Pioglitazone was added to her treatment, and follow-...
Source: Diabetes Metab - February 25, 2009 Category: Endocrinology Authors: Collet-Gaudillat C, Billon-Bancel A, Beressi JP Tags: Diabetes Metab Source Type: journals

Novel mutations of the BSCL2 and AGPAT2 genes in ten families with Berardinelli-Seip congenital generalized lipodystrophy syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: We demonstrated four novel mutations of the BSCL2 and AGPAT2 genes responsible for Berardinelli-Seip syndrome and Brunzell syndrome (AGPAT2-related syndrome). PMID: 19226263 [PubMed - as supplied by publisher] (Source: Clinical Endocrinology)
Source: Clinical Endocrinology - February 18, 2009 Category: Endocrinology Authors: Miranda DM, Wajchenberg BL, Calsolari MR, Aguiar MJ, Silva JM, Ribeiro MG, Fonseca C, Amaral D, Boson WL, Resende BA, De Marco L Tags: Clin Endocrinol (Oxf) Source Type: journals

Bilateral Leser-Trelat Sign Mirroring Lung Adenocarcinoma with Early Metastases to the Contralateral Lung.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present a unique case of bilateral Leser-Trélat sign on the upper torso which mirrored a lung adenocarcinoma of the upper lobes.Page: 216DOI: 10.1097/SMJ.0b013e31818f604dAuthors: Dasanu, Constantin A. MD, PhD; Alexandrescu, Doru T. MD (Source: Southern Medical Journal)
Source: Southern Medical Journal - February 5, 2009 Category: Journals (General) Tags: Abstract HTML PDF (220 K) Source Type: journals

Metabolic syndrome in fifth grade children with acanthosis nigricans: results from the CARDIAC project.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Results are discussed in terms of systematically defining metabolic syndrome for high-risk children, as well as public health and clinical interventions targeting children who are overweight or obese. The presence of AN and morbid obesity might be easily observed markers for metabolic syndrome. PMID: 19172328 [PubMed - in process] (Source: World Journal of Pediatrics : WJP)
Source: World Journal of Pediatrics : WJP - January 28, 2009 Category: Pediatrics Authors: Ice CL, Murphy E, Minor VE, Neal WA Tags: World J Pediatr Source Type: journals

New Survey Results Show Huge Burden of DiabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
January 26, 2009 (NIH) - In the United States, nearly 13 percent of adults age 20 and older have diabetes, but 40 percent of them have not been diagnosed, according to epidemiologists from the National Institutes of Health (NIH) and the Centers for Disease Control and Prevention (CDC), whose study includes newly available data from an Oral Glucose Tolerance Test (OGTT). Diabetes is especially common in the elderly: nearly one-third of those age 65 and older have the disease. An additional 30 percent of adults have pre-diabetes, a condition marked by elevated blood sugar that is not yet in the diabetic range. The researcher...
Source: Diabetes News from dLife.com - January 26, 2009 Category: Consumer Health News Authors: dlife Source Type: info

Berardinelli-Seip syndrome in a 6-year-old boyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Babu Priya, Sharma Rakesh, Jayaseelan Elizabeth, Appachu DivyaIndian Journal of Dermatology, Venereology and Leprology 2008 74(6):644-646A 6-year-old boy presented with abnormal habitus since birth, delayed language development, history of frequent falls since 9 months, and fever since 1 week. He was found to have hyperandrogenic features, generalized paucity of fat, generalized muscular overdevelopment, and brownish pigmentation over the flexural creases. Skin biopsy demonstrated features suggestive of acanthosis nigricans with an absence of subcutaneous tissue. After further investigation, a diagnosis of Berardinelli-Sei...
Source: Indian Journal of Dermatology, Venereology and Leprology - January 16, 2009 Category: Dermatology Authors: Babu Priya, Sharma Rakesh, Jayaseelan Elizabeth, Appachu Divya Source Type: journals

Serum and intracellular magnesium deficiency in patients with metabolic syndrome-Evidences for its relation to insulin resistance.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, magnesium depletion in serum and mononuclear cells is common in obese people with metabolic syndrome, and it is more evident in non-white people with insulin resistance. This depletion may contribute to a post-receptor insulin resistance. PMID: 19124169 [PubMed - as supplied by publisher] (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - January 3, 2009 Category: Endocrinology Authors: Lima MD, Cruz T, Rodrigues LE, Bomfim O, Melo J, Correia R, Porto M, Cedro A, Vicente E Tags: Diabetes Res Clin Pract Source Type: journals

Parental diabetes, pubertal stage, and extreme obesity are the main risk factors for prediabetes in children and adolescents: a simple risk score to identify children at risk for prediabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The main risk factors for prediabetes were parental diabetes, pubertal stage, and extreme obesity. Screening for prediabetes seems meaningful in subjects with either a parental history of diabetes or a combination of extreme obesity and pubertal stage and detected nearly 90% of the overweight children and adolescents with prediabetes. (Source: Pediatric Diabetes)
Source: Pediatric Diabetes - December 18, 2008 Category: Endocrinology Authors: Thomas Reinehr, Martin Wabitsch, Michaela Kleber, Gideon de Sousa, Christian Denzer, André Michael Toschke Source Type: journals

Prevalence of obesity and metabolic syndrome in Indigenous Australian youthsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We conducted a cross-sectional study of Indigenous youths residing in the Torres Strait region of Australia to assess the prevalence of obesity and the metabolic syndrome. Data on body mass index (BMI), waist circumference, blood pressure, presence of acanthosis nigricans and blood glucose were collected. Fasting glucose, insulin, C-Peptide, HbA1c and lipids were measured, and an oral glucose tolerance test was performed in those with a BMI greater than 25 (childhood-equivalent cut-points) or fasting glucometer reading >5.5 mmol/L. Of 158 youths, 31% were overweight and 15% were obese, 38% had enlarged waist circumference ...
Source: Obesity Reviews - December 16, 2008 Category: Eating Disorders and Weight Management Authors: P. C. Valery, A. Moloney, A. Cotterill, M. Harris, A. K. Sinha, A. C. Green Source Type: journals

NOTABLE NOTES: Type 2 Segmental Acanthosis Nigricans: A Historical Case Explained by a New ConceptEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Archives of Dermatology)
Source: Archives of Dermatology - December 15, 2008 Category: Dermatology Authors: Happle, R. Tags: Notable Notes Source Type: journals

Acanthosis nigricans: A practical approach to evaluation and management.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Acanthosis nigricans is a dermatosis characterized by thickened, hyperpigmented plaques, typically of the intertriginous surfaces and neck. Common in some populations, its prevalence depends on race. Clinicians should recognize acanthosis nigricans; it heralds disorders ranging from endocrinologic disturbances to malignancy. In this review, we discuss the pathogenesis of acanthosis nigricans and its clinical implications and management. PMID: 19061584 [PubMed - in process] (Source: Dermatol Online J)
Source: Dermatol Online J - December 11, 2008 Category: Dermatology Authors: Higgins SP, Freemark M, Prose NS Tags: Dermatol Online J Source Type: journals

Clearance of acanthosis nigricans associated with insulinoma following surgical resectionEmail this article to a colleague. Save this article to My Clippings. discuss this article 1 CommentDiscuss or comment on this article.
We report a case wherein the acanthosis disappeared following surgical resection of insulinoma and this strengthens the hypothesis that hyperinsulinaemia is responsible for acanthosis. (Source: QJM)
Source: QJM - October 20, 2008 Category: Internal Medicine Authors: Ghosh, S., Roychowdhury, B., Mukhopadhyay, S., Chowdhury, S. Tags: Case report Source Type: journals

What every physician should know about polycystic ovary syndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ABSTRACT: Polycystic ovary syndrome (PCOS) is the most common endocrine cause of hirsutism, acne, and pattern alopecia. It is a heterogeneous syndrome of hyperandrogenic anovulation that is typically due to intrinsic ovarian dysfunction, which is often aggravated by insulin-resistant hyperinsulinemia with its risks of diabetes mellitus and metabolic syndrome and their complications. Because there are many pitfalls to androgen assays, evaluation for hyperandrogenemia is suggested in women with moderate or severe hirsutism or hirsutism equivalents, menstrual irregularity, acanthosis nigricans, or intractable obesity. An endo...
Source: Dermatologic Therapy - October 6, 2008 Category: Dermatology Authors: Robert L Rosenfield Tags: Original Articles Source Type: journals

The clinical evaluation of hirsutismEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ABSTRACT: Hirsutism is a disorder of excess growth of terminal hairs in androgen-dependent areas in women. Other cutaneous conditions associated with androgen excess are androgenetic alopecia, acanthosis nigricans, and acne. Hirsutism is often associated with measurably elevated androgen levels, but not in all cases. Androgens in women arise from the ovary and adrenal glands, and peripherally from skin and fat. The most common cause of hirsutism is polycystic ovarian syndrome. Patients with "idiopathic" hirsutism have normal ovulatory cycles and androgen levels. Other causes are late onset congenital adrenal hyperplasia, C...
Source: Dermatologic Therapy - October 6, 2008 Category: Dermatology Authors: Najwa Somani, Shannon Harrison, Wilma F Bergfeld Tags: Original Articles Source Type: journals

Hirsutism: Clinico-investigative profile of 50 Indian patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion:</b> Hirsutism in Indian patients is not uncommon. Adolescent patients appear to be more concerned about hirsutism as compared to those in the older age group who were more often worried of late onset acne. All patients, however, were more concerned for facial hair than those on other body areas signifying that facial hair need to be given higher than current value in F-G score. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - October 2, 2008 Category: Dermatology Authors: Sharma Nand Lal, Mahajan Vikram K, Jindal Rashmi, Gupta Mudita, Lath Anju Source Type: journals

Hypochondroplasia and Acanthosis nigricans: a new syndrome due to the p.Lys650Thr mutation in the fibroblast growth factor receptor 3 gene?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: This is the first report of a large pedigree with the clinical phenotype of HCH plus AN due to a FGFR3 mutation, p.Lys650Thr. This finding demonstrates the coexistence of both conditions due to the same mutation and it might represent a true complex, which should be further established by searching for AN in mild HCH patients or for HCH in patients with AN. PMID: 18583390 [PubMed - in process] (Source: European Journal of Endocrinology)
Source: European Journal of Endocrinology - September 1, 2008 Category: Endocrinology Authors: Castro-Feijóo L, Loidi L, Vidal A, Parajes S, Rosón E, Alvarez A, Cabanas P, Barreiro J, Alonso A, Domínguez F, Pombo M Tags: Eur J Endocrinol Source Type: journals

Prevalence of insulin resistance and its association with metabolic syndrome criteria among Bolivian children and adolescents with obesityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Metabolic syndrome has a prevalence of 36% in children and adolescent population in the study. Insulin resistance was very common among children with obesity with a significant association with high blood pressure and high triglycerides presence. (Source: BMC Pediatrics - Latest articles)
Source: BMC Pediatrics - Latest articles - August 12, 2008 Category: Pediatrics Authors: Margoth Caceres, Carlos G Teran, Susana Rodriguez and Marcos Medina Source Type: journals

Novel subtype of congenital generalized lipodystrophy associated with muscular weakness and cervical spine instabilityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report two siblings of Hispanic origin who displayed characteristic features of CGL such as generalized loss of subcutaneous fat from birth, acanthosis nigricans, acromegaloid habitus, umbilical prominence, hepatosplenomegaly, hypoleptinemia, dyslipidemia, and insulin resistance. However, no disease causing variants were detected in the DNA sequence of AGPAT2, BSCL2 or CAV1 genes. Further, whole body magnetic resonance imaging (MRI) in the two siblings revealed marked loss of subcutaneous, intraabdominal and intrathoracic fat like in other patients with CGL, but preservation of bone marrow fat which is invariably lost i...
Source: American Journal of Medical Genetics Part A - August 12, 2008 Category: Stem Cells Authors: Vinaya Simha, Anil K. Agarwal, Patricia A. Aronin, Susan T. Iannaccone, Abhimanyu Garg Source Type: journals

Prevalence of acanthosis nigricans in relation to anthropometric measures: Community-based cross-sectional study in Korean pre-adolescent school childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: AN has a good correlation with level of adiposity, and was already present in overweight children that were not considered obese by definition. (Source: Pediatrics International)
Source: Pediatrics International - June 28, 2008 Category: Pediatrics Authors: Yoosoo Chang, Hee-Yeon Woo, Eunju Sung, Cheol Hwan Kim, Heetae Kang, Young Su Ju, Kyung Hee Park Source Type: journals

Abnormal venous drainage in syndromic craniosynostosis and the role of CT venographyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Patients with syndromic craniosynostosis often demonstrate abnormal venous anatomy, which can have serious consequences on craniofacial surgery, especially when a posterior decompression is being considered. Based on these findings, the authors assert that those children with some syndromic craniosynostosis being considered for surgery should undergo venographic studies as part of their pre-operative evaluation. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s00381-008-0667-8Authors Dhruve Satish Jeevan, John Radcliffe Hospital Department of Paediatric Neurosurgery West Wi...
Source: Child's Nervous System - June 25, 2008 Category: Pediatrics Tags: Child's Nervous System Source Type: journals

Nevoid acanthosis nigricansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Das Jayanta Kumar, Sengupta Sujata, Gangopadhyay AsokIndian Journal of Dermatology, Venereology and Leprology 2008 74(3):279-280 (Source: Indian Journal of Dermatology, Venereology and Leprology)
Source: Indian Journal of Dermatology, Venereology and Leprology - June 21, 2008 Category: Dermatology Authors: Das Jayanta Kumar, Sengupta Sujata, Gangopadhyay Asok Source Type: journals

Prevalence of acanthosis nigricans in relation to anthropometric measures: Community-based cross-sectional study in Korean pre-adolescent school childrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Pediatrics International, Volume 0, Issue 0, Page ???, OnlineEarly Articles. AbstractBackground: This cross-sectional study was performed to assess the prevalence of acanthosis nigricans (AN) across various anthropometric measures and to identify the cut-offs for anthropometric indices of adiposity for development of AN in Asian ... (Source: Pediatrics International)
Source: Pediatrics International - June 19, 2008 Category: Pediatrics Tags: article Source Type: journals

Nevoid acanthosis nigricansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Das Jayanta Kumar, Sengupta Sujata, Gangopadhyay AsokIndian Journal of Dermatology, Venereology and Leprology 2008 74(3):281-282 (Source: Indian Journal of Dermatology, Venereology and Leprology)
Source: Indian Journal of Dermatology, Venereology and Leprology - June 17, 2008 Category: Dermatology Authors: Das Jayanta Kumar, Sengupta Sujata, Gangopadhyay Asok Source Type: journals

ARTICLE: Primary Amenorrhea as a Manifestation of Polycystic Ovarian Syndrome in Adolescents: A Unique Subgroup?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Adolescents with PA and PCOS exhibit increased features of the metabolic syndrome and higher androstenedione levels and may represent a more severe spectrum of a common condition. (Source: Archives of Pediatrics)
Source: Archives of Pediatrics - June 2, 2008 Category: Pediatrics Authors: Rachmiel, M., Kives, S., Atenafu, E., Hamilton, J. Tags: Nutritional and Metabolic Disorders, Metabolic Diseases, Pediatrics, Adolescent Medicine, Women's Health, Women's Health, Other Article Source Type: journals

Significance of acanthosis nigricans in childhood obesityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we aimed to find the clinical and laboratory differences in obese children with AN and without AN (non-AN). Methods: In ... (Source: Journal of Paediatrics and Child Health)
Source: Journal of Paediatrics and Child Health - May 9, 2008 Category: Pediatrics Tags: article Source Type: journals

Nevoid acanthosis nigricans with subtle melanocyte hyperplasia.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 18489033 [PubMed - in process] (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - May 1, 2008 Category: Dermatology Authors: Colegio OR, McNiff JM, Antaya RJ Tags: J Am Acad Dermatol Source Type: journals