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HERA Requests Applications for Ovarian Cancer StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The HERA Women’s Cancer Foundation, a nationally recognized ovarian cancer nonprofit organization, has announced funding for a study focused on type I ovarian cancer; low-grade serous carcinoma, mucinous carcinoma, malignant Brenner tumor and/or clear cell carcinoma. The research will concentrate on the cause, early detection, treatment, and/or understanding of this disease.Scientists and clinicians of non-profit research, medical service and educational institutions located in the U.S are eligible and encouraged to apply. The one-year award for $100,000 will support direct costs of the project, up to 50 percent of ...
Source: ScanGrants feed - October 8, 2009 Category: Research Authors: HERA Women’s Cancer Foundation Source Type: funding

The Expression and Diagnostic Utility of p63 in the Female Genital TractEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
p63 plays a key role in epithelial development in various organs, being expressed in myoepithelial cells and in basal cells of stratified epithelia. In the female genital tract, p63 is expressed in the basal and parabasal cells of mature cervical, vaginal and vulval squamous epithelium, and also in cervical reserve cells at the transformation zone and in immature metaplastic and atrophic cervical squamous epithelium. In this review, the diagnostic utility of p63 immunohistochemical staining in various pathologic scenarios within the female genital tract is discussed. Cervical microglandular hyperplasia is p63 positive with...
Source: Advances in Anatomic Pathology - August 29, 2009 Category: Pathology Tags: Review Articles Source Type: journals

Brenner tumor in pregnancy: Clinical approach and pathological findingsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Brenner tumor is an uncommon ovarian tumor in pregnancy with only three previous cases in the English published reports. A 35-year-old woman delivered abdominally because of distress symptoms and a Brenner tumor was resected incidentally. Histological examination revealed a tumor composed of epithelial nests and areas of stromal luteinization. The patient was treated conservatively. Brenner tumor should be considered in the differential diagnosis of adnexal masses during pregnancy. These tumors are mainly benign and show typical luteinization associated with the hormonal milieu in pregnancy. (Source: Journal of Obstetr...
Source: Journal of Obstetrics and Gynaecology Research - November 26, 2008 Category: OBGYN Authors: Ali Gedikbasi, Volkan Ulker, Ovgu Aydin, Alpaslan Akyol, Ceyhun Numanoglu, Yavuz Ceylan Source Type: journals

Exploring the histogenesis of ovarian mucinous and transitional cell (Brenner) neoplasms and their relationship with Walthard cell nests: a study of 120 tumors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The strong association of mucinous and transitional cell components, similar type of calcification, complementary size distributions, and frequent identification of a transitional component in the face of an exceedingly small estimated proportion of that component suggest that this association has been underestimated. The association of Brenner tumors with Walthard nests, although significant, appears weak and not strongly supportive of a histogenetic relationship. The stronger association of Walthard nests with mucinous tumors remains unexplained. PMID: 18976011 [PubMed - in process] (Source: Archives of ...
Source: Archives of Pathology and Laboratory Medicine - November 1, 2008 Category: Laboratory Medicine Authors: Seidman JD, Khedmati F Tags: Arch Pathol Lab Med Source Type: journals

Malignant Brenner Tumor With Transition From Benign to Malignant Components: Computed Tomographic and Magnetic Resonance Imaging Findings With Pathological Correlation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 553DOI: 10.1097/RCT.0b013e3181506643Authors: Takeuchi, Mayumi MD, PhD *; Matsuzaki, Kenji MD, PhD *; Sano, Nobuya MD, PhD +; Furumoto, Hiroyuki MD, PhD ++; Nishitani, Hiromu MD, PhD * (Source: Journal of Computer Assisted Tomography)
Source: Journal of Computer Assisted Tomography - July 30, 2008 Category: Radiology Tags: Abstract HTML PDF (263 K) Source Type: journals

[Proliferating Brenner tumor: Case report.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Brenner tumors account for only 1 to 2% of ovarian tumors. Proliferating Brenner tumors are characterized by an epithelial proliferation, resembling superficial well-differentiated urothelial carcinomas. A single 29-year-old patient was operated for an ovarian tumor. On gross examination, the tumor, which originated in the left ovary, was cystic multilocular and presented polyoid excrescences. Definitive histological exam showed a papillary proliferation lined by transitional cells without stroma infiltration. Mucinous cells lined some cavities. The diagnosis of proliferating Brenner tumor was made. Clinical and pathol...
Source: Gynecologie, Obstetrique & Fertilite - March 4, 2008 Category: OBGYN Authors: Kourda N, Elloumi H, Chérif K, Jilani SB, Zermani R Tags: Gynecol Obstet Fertil Source Type: journals

p63 expression in ovarian tumours: a marker for Brenner tumours but not transitional cell carcinomasEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Histopathology Volume 51, Issue 4, Page 477-483, Oct 2007. Liao X Y, Xue W C, Shen D H, Ngan H Y S, Siu M K & Cheung A N(2007) Histopathology 51, 477–483p63 expression in ovarian tumours: a marker for Brenner tumours but not transitional cell carcinomasAims: To investigate p63 expression in ovarian neoplasms.Metho... (Source: Histopathology)
Source: Histopathology - September 18, 2007 Category: Pathology Tags: Original articles Source Type: journals

[Brenner tumour of the vagina]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a sixth case and discuss the histogenesis of this tumour, as well as the differential diagnosis with the mixed tumour of the vagina. PMID: 18185458 [PubMed - indexed for MEDLINE] (Source: Annales de Pathologie)
Source: Annales de Pathologie - September 1, 2007 Category: Pathology Authors: Gelly-Marty M, Assous D, Padéano MM, Arnould L Tags: Ann Pathol Source Type: journals

Transitional Cell Carcinoma of the Endometrium Associated With Benign Ovarian Brenner Tumor: A Case Report With Immunohistochemistry Molecular Analysis and a Review of the Literature.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 298DOI: 10.1097/01.pgp.0000236943.28969.b2Authors: Giordano, Giovanna M.D.; D'Adda, Tiziana B.Sc.D.; Gnetti, Letizia M.D.; Merisio, Carla M.D.; Raboni, Stefano M.D. (Source: International Journal of Gynecological Pathology)
Source: International Journal of Gynecological Pathology - June 21, 2007 Category: Pathology Tags: Abstract HTML PDF (1.515 M) Source Type: journals

Three synchronized neoplasms of the female genital tract: an extraordinary presentationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of unusual co-existence of multiple primary neoplasms of female genital tract. Case A 62-year-old gravida 2, para 2 was referred with spotting and vaginal discharge for about 6 months. Fractionate curettage was performed and documented endocervical squamous cell carcinoma in situ. Subsequently total abdominal hysterectomy and bilateral salphingo-oophorectomy was performed. Final pathological report demonstrated cervical squamous cell carcinoma, right ovarian Brenner tumor, left ovarian granulosa tumor and endometrial polyps. Discussion Multiple primary neoplasms...
Source: Archives of Gynecology and Obstetrics - May 24, 2007 Category: OBGYN Tags: Archives of Gynecology and Obstetrics Source Type: journals

HPV induced ovarian squamous cell carcinoma: case report and review of the literatureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion??The development of bone metastases in association with an ovarian squamous cell carcinoma is a rare finding, and it did not respond to treatment with a tyrosine kinase. A review of literature is presented. Content TypeJournal Article JournalArchives of Gynecology and ObstetricsOnline ISSN 1432-0711Print ISSN 0932-0067 (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - March 2, 2007 Category: OBGYN Tags: Archives of Gynecology and Obstetrics Source Type: journals

Feasibility of screening for ovarian cancer using symptoms as selection criteria.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: This pilot study confirms the feasibility of screening for ovarian cancer using symptoms as selection criteria. Specificity was high and patient compliance good. Initial concerns about referral volumes and additional investigations and referrals generated were not confirmed. No ovarian cancers were detected in this pilot study, and this may be due to the size of the cohort. PMID: 17233861 [PubMed - in process] (Source: BJOG : An International Journal of Obstetrics and Gynaecology)
Source: BJOG : An International Journal of Obstetrics and Gynaecology - January 1, 2007 Category: OBGYN Authors: Rufford BD, Jacobs IJ, Menon U Tags: BJOG Source Type: journals

[RSNA Education Exhibits] Developing an MR Imaging Strategy for Diagnosis of Ovarian MassesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Magnetic resonance (MR) imaging provides useful information for characterization of various ovarian masses as neoplastic or nonneoplastic and, when neoplastic, on a spectrum from benign to malignant. The use of MR imaging for diagnosis of ovarian masses includes consideration of morphologic characteristics and signal intensity characteristics on T1- and T2-weighted images. The morphologic characteristics of cystic masses, cystic and solid masses, and predominantly solid masses provide important information. In general, cystic masses represent benign tumors, whereas cystic and solid masses are strongly associated with malig...
Source: Radiographics recent issues - September 14, 2006 Category: Radiology Authors: Imaoka, I., Wada, A., Kaji, Y., Hayashi, T., Hayashi, M., Matsuo, M., Sugimura, K. Tags: Magnetic Resonance Imaging, Obstetric/Gynecologic Radiology, Genitourinary Radiology RSNA Education Exhibits Source Type: journals

Expression and subcellular localization of maspin in human ovarian epithelial neoplasms: correlation with clinicopathologic features.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Maspin was expressed in a substantial proportion of ovarian tumors with poor prognostic parameters. These results may offer new insights regarding the role of maspin in ovarian cancer that may also impact diagnosis and treatment strategies. Moreover, variation in maspin expression between Brenner tumor and other epithelial surface ovarian tumors may indicate that the different histological types probably represent distinct disease entities and involve different molecular pathways. PMID: 16799655 [PubMed - in process] (Source: J Egypt Natl Canc In...)
Source: J Egypt Natl Canc In... - September 14, 2005 Category: Cancer & Oncology Authors: Abd El-Wahed MM Source Type: journals