Group B StreptococcusThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you your search results in order of date.

Pages: 1 2 3 4 5

247 records returned

The Tpl2 Mutation Sluggish Impairs Type I IFN Production and Increases Susceptibility to Group B Streptococcal Disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sluggish was identified in a population of third generation mice descended from N-ethyl-N-nitrosourea-mutagenized sires. Macrophages from homozygotes exhibited impaired TNF-alpha production in response to all TLR ligands tested and displayed impaired type I IFN production in response to TLR7 and TLR9 stimulations. The phenotype was confined to a critical region on mouse chromosome 18 and then ascribed to a T to A transversion in the acceptor splice site of intron 4 at position 13346 of the Map3k8 gene, resulting in defective splicing. The Map3k8(Sluggish) mutation does not result in susceptibility to viral infections, ...
Source: Journal of Immunology - November 18, 2009 Category: Allergy & Immunology Authors: Xiao N, Eidenschenk C, Krebs P, Brandl K, Blasius AL, Xia Y, Khovananth K, Smart NG, Beutler B Tags: J Immunol Source Type: journals

Structure of laminin-binding adhesin (Lmb) from Streptococcus agalactiaeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Adhesion/invasion of pathogenic bacteria is a critical step in infection and is mediated by surface-exposed proteins termed adhesins. The crystal structure of recombinant Lmb, a laminin-binding adhesin from Streptococcus agalactiae, has been determined at 2.5 Å resolution. Based on sequence and structural homology, Lmb was placed into the cluster 9 family of the ABC (ATP-binding cassette) transport system. The structural organization of Lmb closely resembles that of ABC-type solute-binding proteins (SBPs), in which two structurally related globular domains interact with each other to form a metal-binding cavity at the...
Source: Acta Crystallographica Section D - November 17, 2009 Category: Biochemistry Authors: Ragunathan, P.Spellerberg, B.Ponnuraj, K. Tags: adhesins metal transporters surface proteins laminin binding ATP-binding cassette solute-binding proteins research papers Source Type: journals

Intranasal immunization with GBS surface protein Sip and ScpB induces specific mucosal and systemic immune responses in miceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this study, we constructed and expressed the two proteins, and investigated their specific mucosal immune responses against GBS induced by intranasal immunization with cholera toxin (CT) and CpG-oligodeoxynucleotides (CpG-ODNs). Intranasal immunization with different doses of recombinant Sip and ScpB all elicited specific antibodies in serum and vagina of mice. A combination of rSip and rScpB with either CT or CpG-ODN elicited specific antibodies in serum and vaginal samples. Th1 responses were enhanced by CpG and CT. Sera from the mice group intranasally immunized with rSip+CT, rScpB+CT, rSip+rScpB+CT, and rSip+rScpB+C...
Source: FEMS Immunology and Medical Microbiology - November 12, 2009 Category: Microbiology Authors: Guanhua Xue, Lihua Yu, Shentao Li, Xuzhuang Shen Source Type: journals

Group B Strep InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Group B Strep (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 11, 2009 Category: Journals (General) Source Type: info

First Group B Streptococcal Vaccine Prevents Colonization in Healthy Nonpregnant WomenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A phase 3 study shows, for the first time, the feasibility of immunization against Group B streptococcus infection; an investigational vaccine prevents vaginal colonization. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 3, 2009 Category: Consumer Health News Tags: Infectious Diseases Source Type: news

IDSA: Strep Vaccine Safe, Effective in Early Trial (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PHILADELPHIA (MedPage Today) -- An investigational vaccine against one strain of group B streptococcus was safe and modestly effective, a researcher said here. (Source: MedPage Today Product Alert)
Source: MedPage Today Product Alert - November 2, 2009 Category: Drugs & Pharmacology Source Type: news

Progress Made On Group B Streptococcus VaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
WHAT: Scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have completed a Phase II clinical study that indicates a vaccine to prevent Group B Streptococcus (GBS) infection is possible. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 2, 2009 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

Group B Strep Vaccine ProgressEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Progress in Quest for Group B Strep Vaccine (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 2, 2009 Category: Journals (General) Source Type: info

Progress in Quest for Group B Strep VaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Researchers are a step closer to developing a vaccine to protect pregnant women against a serious bacterial infection that is a leading cause of death and disability in newborns. (Source: WebMD Health)
Source: WebMD Health - October 30, 2009 Category: Consumer Health News Source Type: news

Experimental group B strep vaccine shows promiseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CHICAGO (Reuters) - An experimental vaccine cut the chances of a pregnant woman carrying group B strep bacteria, a leading cause of blood and brain infections in newborns, U.S. researchers said on Friday. (Source: Reuters: Health)
Source: Reuters: Health - October 30, 2009 Category: Consumer Health News Tags: healthNews Source Type: news

Evaluation of Universal Antenatal Screening for Group B Streptococcus.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 703DOI: 10.1097/01.ogx.0000361379.05189.55Authors: Van Dyke, Melissa K.; Phares, Christina R.; Lynfield, Ruth; Thomas, Ann R.; Arnold, Kathryn E.; Craig, Allen S.; Mohle-Boetani, Janet; Gershman, Ken; Schaffner, William; Petit, Susan; Zansky, Shelley M.; Morin, Craig A.; Spina, Nancy L.; Wymore, Kathryn; Harrison, Lee H.; Shutt, Kathleen A.; Bareta, Joseph; Bulens, Sandra N.; Zell, Elizabeth R.; Schuchat, Anne; Schrag, Stephanie J. (Source: Obstetrical & Gynecological Survey)
Source: Obstetrical & Gynecological Survey - October 30, 2009 Category: OBGYN Tags: Abstract HTML PDF (799 K) Source Type: journals

Progress made on group B streptococcus vaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(NIH/National Institute of Allergy and Infectious Diseases) Scientists supported by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, have completed a phase II clinical study that indicates a vaccine to prevent Group B Streptococcus infection is possible. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 30, 2009 Category: Global & Universal Source Type: news

Progress Made On Group B Streptococcus VaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Scientists have completed a phase II clinical study that indicates a vaccine to prevent Group B Streptococcus infection is possible. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 30, 2009 Category: Science Source Type: news

New Genetic Material From Group B Streptococcus IdentifiedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Group B Streptococcus is a versatile pathogen that affects a variety of animals. Now studies are revealing new information about this pathogen. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 23, 2009 Category: Science Source Type: news

Asymptomatic Bacteriuria in Pregestational Diabetic Pregnancies and the Role of Group B StreptococcusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Amer J PerinatolDOI: 10.1055/s-0029-1239485ABSTRACTWe sought to determine if gravidas with pregestational diabetes mellitus (DM) are at increased risk for asymptomatic bacteriuria (ASB) compared with nondiabetic gravidas. This is a retrospective case-control study of 150 pregnant patients with pregestational DM and 294 nondiabetic controls. Rates of ASB and any colony count of group B streptococcus (GBS) bacteriuria were reviewed. The incidence of ASB among pregestational diabetics was higher compared with nondiabetic gravidas (18% versus 8.2%, odds ratio [OR] 2.47, 95% confidence interval [CI] 1.37 to 4.45). GBS was the m...
Source: American Journal of Perinatology - October 16, 2009 Category: Perinatology & Neonatology Source Type: journals

Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides [Immunology]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Group B Streptococcus (GBS) causes serious infection in neonates and is an important target of vaccine development. Zwitterionic polysaccharides (ZPS),... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - October 13, 2009 Category: Science Authors: Gallorini, S., Berti, F., Mancuso, G., Cozzi, R., Tortoli, M., Volpini, G., Telford, J. L., Beninati, C., Maione, D., Wack, A. Tags: Immunology Source Type: journals

Very Late‐Onset Group B Streptococcus Meningitis, Sepsis, and Systemic Shigellosis due to Interleukin‐1 Receptor–Associated Kinase‐4 DeficiencyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a child with very late‐onset group B Streptococcus sepsis and meningitis, systemic shigellosis, and chronic osteomyelitis. Peripheral blood cells obtained from the patient and her brother did not respond to stimulation with either interleukin‐1β or lipopolysaccharide. Sequencing of the interleukin‐1 receptor–associated kinase‐4 gene revealed 2 novel mutations. (Source: Clinical Infectious Diseases Latest Issue)
Source: Clinical Infectious Diseases Latest Issue - October 8, 2009 Category: Infectious Diseases Tags: article BRIEF REPORT Source Type: journals

Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: Phenotypic and functional impactEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Group B Streptococcus (GBS) is an important human pathogen and a model system for studying the roles of bacterial glycosylation in host–microbe interactions. Sialic acid (Sia), expressed prominently in the GBS capsular polysaccharide (CPS), mimics mammalian cell surface Sia and can interact with host Sia-binding proteins to subvert immune clearance mechanisms. Our earlier work has shown that GBS partially O-acetylates CPS Sia residues and employs an intracellular O-acetylation/de-O-acetylation cycle to control the final level of this surface Sia modification. Here, we examine the effects of point mutations in the Neu...
Source: Glycobiology - October 6, 2009 Category: Biology Authors: Weiman, S., Dahesh, S., Carlin, A. F, Varki, A., Nizet, V., Lewis, A. L Tags: Original Article Source Type: journals

Group B streptococcus meningitis in a child with cochlear implant.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a case of GBS meningitis in a 6-year-old boy with a cochlear implant. PMID: 19861082 [PubMed - in process] (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - October 1, 2009 Category: Infectious Diseases Authors: Glikman D, Luntz M, Shihada R, Zonis Z, Even L Tags: Emerg Infect Dis Source Type: journals

Inappropriate use of vancomycin for preventing perinatal group B streptococcal (GBS) disease in laboring patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Perinatal Medicine 37 (5): 487-489 Abstract Objective: The 2002 CDC guidelines for the prevention of perinatal group B streptococcus (GBS) stipulate that vancomycin is reserved for penicillin-allergic women at high risk for beta-lactam anaphylaxis with resistance to clindamycin or erythromycin. Our objective was to evaluate practitioner adherence to these guidelines. Methods: This is a retrospective chart review of patients admitted to labor and delivery who received vancomycin for GBS prophylaxis from January 1st, 2005 to June 1st, 2007. Identification and documentation of allergic reactions to beta lactams and...
Source: Journal of Perinatal Medicine - September 3, 2009 Category: Perinatology & Neonatology Source Type: journals

Universal Newborn Screening for Group B Streptococcus Was Rapidly AdoptedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The study, published in the June 18, 2009, issue of the NEJM also notes that improved testing of preterm infants may help reduce cases of GBS in newborns. Medscape Pediatrics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 3, 2009 Category: Consumer Health News Tags: Pediatrics Source Type: news

Clinical aspects of invasive infections with Streptococcus dysgalactiae ssp. equisimilis in Japan: differences with respect to Streptococcus pyogenes and Streptococcus agalactiae infectionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Clin Microbiol Infect Streptococcus dysgalactiae ssp. equisimilis (SDSE) is increasingly being identified as a pathogen responsible for invasive and non-invasive infections. We compared the clinical features of invasive SDSE infections with those of invasive infections caused by Streptococcus pyogenes (group A streptococcus (GAS)) and Streptococcus agalactiae (group B streptococcus (GBS)). Active surveillance for invasive SDSE, GAS and GBS was maintained over 1 year at 142 medical institutions throughout Japan. Clinical information was collected together with isolates, which were characterized microbiologically. Two hundre...
Source: Clinical Microbiology and Infection - September 1, 2009 Category: Microbiology Authors: T. Takahashi, K. Sunaoshi, K. Sunakawa, S. Fujishima, H. Watanabe, K. Ubukata Source Type: journals

Diversity in cytokine response to bacteria associated with preterm birth by fetal membranesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Fetal membrane cytokine signatures of 4 different bacteria associated with PTB are distinct, suggesting that infection as a potential cause of PTB is not homogeneous in its presentation. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - August 31, 2009 Category: OBGYN Authors: Ramkumar Menon, Morgan R. Peltier, Judith Eckardt, Stephen J. Fortunato Tags: Selected papers from the 29th annual meeting (The Pregnancy Meeting) of the Society for Maternal-Fetal Medicine Source Type: journals

Painless blood testing to prevent neonatal sepsis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The current US guidelines advise that all women colonized with Group B streptococcus (GBS) at 35-37 weeks, as well as those laboring before this time and all women with GBS urinary tract infections, should be offered intrapartum antibiotic prophylaxis, usually in the form of high-dose intravenous penicillin or ampicillin, unless delivered by planned cesarean section before the onset of labor in a woman with intact membranes. In term and preterm babies who are born to treated women, in addition to babies who act ill, the recommendation is to treat the baby with antibiotics. In certain circumstances, such as when the mot...
Source: WMJ - August 31, 2009 Category: Journals (General) Authors: Costakos DT, Walden J, Rinzel MT, Dahlen L Tags: WMJ Source Type: journals

[Original articles] Group B streptococcal disease in infants: a case control studyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Independent of birth weight, a number of maternal, birth and neonatal factors are significantly associated with GBS disease. The management of babies with GBS disease results in an appreciable use of hospital resources. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - August 20, 2009 Category: Pediatrics Authors: Heath, P T, Balfour, G F, Tighe, H, Verlander, N Q, Lamagni, T L, Efstratiou, A, on behalf of the HPA GBS Working Group Tags: Epidemiologic studies, Drugs: cardiovascular system, Child health, Arrhythmias Original articles Source Type: journals

Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the unexpected discovery that certain GBS strains may bind one such receptor, hSiglec-5, in a Sia-independent manner, via the cell wall–anchored β protein, resulting in recruitment of SHP protein tyrosine phosphatases. Using a panel of WT and mutant GBS strains together with Siglec-expressing cells and soluble Siglec-Fc chimeras, we show that GBS β protein binding to Siglec-5 functions to impair human leukocyte phagocytosis, oxidative burst, and extracellular trap production, promoting bacterial survival. We conclude that protein-mediated functional engagement of an inhibitory host lectin receptor...
Source: The Journal of Experimental Medicine - August 2, 2009 Category: Internal Medicine Authors: Carlin, A. F., Chang, Y.-C., Areschoug, T., Lindahl, G., Hurtado-Ziola, N., King, C. C., Varki, A., Nizet, V. Tags: Brief Definitive Reports Source Type: journals

Group B Streptococcus induces tyrosine phosphorylation of annexin V and glutathione S-transferase in human umbilical vein endothelial cells.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to investigate the molecular mechanisms underlying GBS-HUVEC interaction, focusing specifically on the responsiveness of host protein tyrosine kinase (PTK). We found that GBS serotypes III and V induced actin reorganization and formation of stress fibers into HUVECs. Since rearrangements of the actin cytoskeleton into eukaryotic cells are usually associated with the activation of PTK, we decided to follow the expression of this class of kinases in the course of the interaction. Unexpectedly, treatment of HUVECs with genistein greatly increased both cytoadherence and intracellular viability, ...
Source: International Journal of Molecular Medicine - July 30, 2009 Category: Molecular Biology Authors: Santos GS, Loureiro Y Penha CV, Mattos-Guaraldi AL, Attias M, Lopes-Bezerra LM, Silva-Filho FC, Nagao PE Tags: Int J Mol Med Source Type: journals

Leading Pathogen In Newborns Can Suppress Immune Cell FunctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Group B Streptococcus (GBS), a bacterial pathogen that causes sepsis and meningitis in newborn infants, is able to shut down immune cell function in order to promote its own survival, according to new research. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - July 27, 2009 Category: Science Source Type: news

AcroMetrix Announces The Release Of OptiQual(R) GBS Positive Control For Use With Diagnostic Assays That Detect Group B StreptococcusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
AcroMetrix, a leading manufacturer of quality control standards and controls for clinical diagnostic and blood testing laboratories, announced the release of the first standardized quality control for molecular Group B Streptococcus (GBS) testing. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 16, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Immune Cell Function Can Be Suppressed By Leading Pathogen In NewbornsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Group B Streptococcus (GBS), a bacterial pathogen that causes sepsis and meningitis in newborn infants, is able to shut down immune cell function in order to promote its own survival, according to researchers at the University of California, San Diego School of Medicine and the Skaggs School of Pharmacy and Pharmaceutical Sciences. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 14, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Leading pathogen in newborns can suppress immune cell functionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(University of California - San Diego) Group B Streptococcus (GBS), a bacterial pathogen that causes sepsis and meningitis in newborn infants, is able to shut down immune cell function in order to promote its own survival, according to researchers at the University of California, San Diego School of Medicine and the Skaggs School of Pharmacy and Pharmaceutical Sciences. Their study, published online July 13 in the Journal of Experimental Medicine, offers insight into GBS infection. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2009 Category: Global & Universal Source Type: news

Protect Your Baby from Group B StrepEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Source: Centers for Disease Control and Prevention Related MedlinePlus Topics: Infections and Pregnancy, Streptococcal Infections (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 9, 2009 Category: Consumer Health News Source Type: consumer

BibA Induces Opsonizing Antibodies Conferring In Vivo Protection against Group B StreptococcusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, we propose BibA as a novel GBS vaccine candidate. (Source: The Journal of Infectious Diseases Latest Issue)
Source: The Journal of Infectious Diseases Latest Issue - July 8, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

IL-4 Deficiency Decreases Mortality but Increases Severity of Arthritis in Experimental Group B Streptococcus InfectionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
IL-4 is an anti-inflammatory cytokine that inhibits the onset and severity in different experimental arthritis models. Group B streptococci (GBS) have been recognized as an ever-growing cause of serious invasive infections in nonpregnant adults. Septic arthritis is a clinical manifestation of GBS infection. To investigate the role of IL-4 in experimental GBS infection, IL-4 deficient or competent mice were inoculated with 1×107 GBS/mouse. Mortality, appearance of arthritis, GBS growth in the organs, and local and sys...
Source: Mediators of Inflammation - July 7, 2009 Category: Biochemistry Source Type: journals

Group B Strep Screening Guidelines Sparing NewbornsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Group B Strep Screening Guidelines Sparing NewbornsCategory: Health NewsCreated: 6/18/2009 7:00:00 AMLast Editorial Review: 7/7/2009 (Source: MedicineNet Senior Health General)
Source: MedicineNet Senior Health General - July 7, 2009 Category: Geriatrics Source Type: consumer

Group B Strep Screening Guidelines Sparing NewbornsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Group B Strep Screening Guidelines Sparing NewbornsCategory: Health NewsCreated: 6/18/2009 7:00:00 AMLast Editorial Review: 7/7/2009 (Source: MedicineNet Womens Health General)
Source: MedicineNet Womens Health General - July 7, 2009 Category: OBGYN Source Type: consumer

Group B Strep Screening Guidelines Sparing NewbornsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: Group B Strep Screening Guidelines Sparing NewbornsCategory: Health NewsCreated: 6/18/2009 7:00:00 AMLast Editorial Review: 7/7/2009 (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - July 7, 2009 Category: Pediatrics Source Type: consumer

Diagnostic Accuracy of a Rapid Real‐Time Polymerase Chain Reaction Assay for Universal Intrapartum Group B Streptococcus ScreeningEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Clinical Infectious Diseases, Volume 0, Issue 0, Page 000, Latest Articles. Background. Intrapartum antibiotic prophylaxis is currently given to mothers who test positive for group B streptococcus (GBS) by antenatal culture‐based screening, with a risk‐based approach for cases with an unknown GBS status. A rapid real‐time polymerase chain reaction (PCR) assay for the detection of GBS became available recently, making intrapartum screening possible. We aimed to assess its diagnostic accuracy and to compare it with antenatal screening. Methods. We conducted a prospective study in a French hospital. All preg...
Source: Clinical Infectious Diseases Latest Issue - July 6, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

Prevention of Group B Streptococcus early-onset disease: a toolkit by the California Perinatal Quality Care CollaborativeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
; D Wirtschafter (Source: Journal of Perinatology)
Source: Journal of Perinatology - July 5, 2009 Category: Perinatology & Neonatology Authors: R J PowersD Wirtschafter Source Type: journals

Prenatal Group BEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Objective: The aim of this study was to evaluate the percentage of pregnant women with negative Group B Streptococcus (GBS) screening results by culture at 35 weeks' gestation, who subsequently had positive GBS test results after 39 weeks' gestat ...more (Source: Taiwanese Journal of Obstetrics and Gynecology)
Source: Taiwanese Journal of Obstetrics and Gynecology - July 1, 2009 Category: OBGYN Source Type: journals

Postoperative Pubic Symphysis Osteomyelitis after Laparoscopic Two-team Sling with Anterior and Posterior ColporrhaphyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: A 53 year-old woman, who previously had a Burch colposuspension, developed osteomyelitis of the pubic symphysis about 1 month after undergoing a laparoscopic 2-team sling with anterior and posterior colporrhaphy. The diagnosis was made on the basis of computed tomography–guided aspiration of the pubic symphysis, which was positive for group B Streptococcus sp. To our knowledge, this is the first case report of osteomyelitis after a laparoscopic retropubic sling procedure. Osteomyelitis is a rare postoperative complication in female pelvic reconstructive surgery but has been reported in cases where the pubic bo...
Source: The Journal of Minimally Invasive Gynecology - June 30, 2009 Category: OBGYN Authors: Jamie Kroft, Rose C. Kung Tags: Case Reports Source Type: journals

Vaginal carriage and antibiotic susceptibility profile of group B Streptococcus during late pregnancy in Ismailia, EgyptEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Summary: Group B Streptococcus (GBS) infection has long been recognized as a frequent cause of morbidity and mortality in newborn infants. The purpose of this study was to determine the colonization rate with GBS and the antibiotic susceptibility profile in pregnant women attending Gynecological clinics in Egypt. One-hundred and fifty vaginal swabs were collected from pregnant women at 35–40 weeks of gestation. In comparison to culture, direct latex agglutination testing revealed 100% sensitivity and 93.75% specificity. Thirty-eight specimens (25.3%) were found to be positive for GBS. Each isolate was tested for suscepti...
Source: Journal of Infection and Public Health - June 25, 2009 Category: Global & Universal Authors: Sarah Ahmed Abd El-kawy Shabayek, Salah Mohamed Abdalla, Abouzeid M.H. Abouzeid Tags: Original Articles Source Type: journals

Test For Strep Bacteria In Pregnant Women Misses More Cases Than Expected, Study ShowsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A federal recommendation that all pregnant women undergo testing for Group B strep bacteria has helped increase the number of screenings but also has produced a high level of false negatives, according to a study published Thursday in the New England Journal of Medicine, the (Source: Medical Devices News From Medical News Today)
Source: Medical Devices News From Medical News Today - June 22, 2009 Category: Medical Equipment Tags: Pregnancy / Obstetrics Source Type: news

Test For Germ In Pregnant Women FaultyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
High Rate Of False Test Results For Group B Strep Caused Some Infants To Miss Treatment (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - June 18, 2009 Category: Consumer Health News Source Type: news

Group B Strep Screening Guidelines Sparing NewbornsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
More expectant moms being checked, treated so babies aren't infected, study finds. Source: HealthDay (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - June 17, 2009 Category: Consumer Health News Source Type: consumer

Combining Microarray Technology and Molecular Epidemiology to Identify Genes Associated with Invasive Group B StreptococcusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Many bacterial species function as both commensals and pathogens; we used this dual nature to develop a high-throughput molecular epidemiological approach to identifying bacterial virulence genes. We applied our approach to Group B Streptococcus (GBS). Three representative commensal and one invasive GBS isolates were selected as tester strains from a population-based collection. We used microarray-based comparative genomic hybridization to identify open reading frames (ORFs) present in two sequenced invasive strains, but absent or divergent in tester strains. We screened 23 variable ORFs against 949 GBS isolates using a GB...
Source: Interdisciplinary Perspectives on Infectious Diseases - June 9, 2009 Category: Infectious Diseases Source Type: journals

Group B Streptococcus and Early-Onset Sepsis in the Era of Maternal ProphylaxisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Despite an era of marked success with universal screening, Group B Streptococcus (GBS) continues to be an important cause of early-onset sepsis, and thus remains a significant public health issue. Improved eradication of GBS colonization and disease may involve universal screening in conjunction with rapid diagnostic technologies or other novel approaches. Given the complications and potential limitations associated with maternal intrapartum prophylaxis, however, vaccines may be the most effective means of preventing neonatal GBS disease. The global utility of conjugated GBS vaccines may be hampered by the variability of s...
Source: Pediatric Clinics of North America - May 31, 2009 Category: Pediatrics Authors: Joyce M. Koenig, William J. Keenan Source Type: journals

AdvanDx Receives FDA 510(k) Clearance For GBS PNA FISH(R) For Rapid Detection Of Group B Strep From Lim BrothsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
AdvanDx announced it received FDA 510(k) clearance for GBS PNA FISH® for detection of Streptococcus agalactiae, aka Group B Strep, from turbid Lim Broths inoculated with vaginal and rectal swabs obtained from pregnant women between 35 and 37 weeks gestation. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 19, 2009 Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news