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Vaccines: Hyperhaemolysis (first reports with meningococcal vaccine groups A C Y W-135 polysaccharide and Hib vaccine conjugate) in an EBV-infected patient: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - November 16, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Pattern of functional antibody activity against Haemophilus influenzae type b (Hib) in infants immunized with diphtheria-tetanus-pertussis/Hib Brazilian combination vaccine.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We evaluated the functional activity of Haemophilus influenzae B (Hib) antibodies elicited in a group of infants immunized with the diphtheria-tetanus-pertussis vaccine combined with an Hib vaccine produced totally in Brazil after technological transfer of Hib vaccine production from Glaxo SmithKline, Belgium. Blood samples from immunized infants (N = 985) were collected for the determination of Hib antibodies. Total Ig and IgM and IgG subclasses of antibodies against polyribosyl ribitol phosphate (PRP) were analyzed by ELISA. Almost all vaccinees (97.56%, 961/985) developed a strong anti-PRP IgG antibody response (>...
Source: Braz J Med Biol Res - November 6, 2009 Category: Research Authors: Matos DC, Silva AM, Neves PC, Martins RM, Homma A, Marcovistz R Tags: Braz J Med Biol Res Source Type: journals

Haemophilus influenzae serotype b conjugate vaccine failure in twelve countries with established national childhood immunization programmesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Clin Microbiol Infect The present study describes the clinical and immunological features of children with Hib vaccine failure, who were identified through national surveillance between 1996 and 2001 in Europe, Israel and Australia. True vaccine failure was defined as invasive Hib disease occurring [ge]2 weeks after one dose, given after the first birthday, or [ge]1 week after [ge]2 doses, given at (Source: Clinical Microbiology and Infection)
Source: Clinical Microbiology and Infection - November 5, 2009 Category: Microbiology Authors: S. Ladhani, P. T. Heath, M. P. E. Slack, P. B. McIntyre, J. Diez-Domingo, J. Campos, R. Dagan, M. E. Ramsay Source Type: journals

Hib vaccine conjugate: Lack of efficacy in a child, leading to Hib epiglottitis: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - October 26, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Effect of probiotic supplementation on immunoglobulins, isoagglutinins and antibody response in children of low socio-economic statusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Supplementation of standard fermented milk with additional probiotics was not of benefit. The high natural rate of early microbial exposure in infants and children from a population of low socio-economic status living in a “less hygienic environment” may account for the absence of an additional immune-stimulating effect by supplementary probiotics. Content Type Journal ArticleCategory Original ContributionDOI 10.1007/s00394-009-0063-5Authors Néstor Pérez, Hospital de Niños de La Plata, Comisión de Investigaciones Científicas de la Provincia de Buenos Aires (CICPBA) Unidad de Inmun...
Source: European Journal of Nutrition - October 16, 2009 Category: Nutrition Tags: European Journal of Nutrition Source Type: journals

South Asia News in brief: 2–14 October 2009Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Scientists produce biofuel from water hyacinths, global climate models adjusted for local use, Bhutan to introduce Hib vaccine, and more. (Source: SciDev.Net)
Source: SciDev.Net - October 14, 2009 Category: Global & Universal Source Type: info

CDC, AAFP Recommending Recall of Children in Need of Hib Booster DoseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
As the nation's supply of Haemophilus influenzae type b, or Hib, vaccine increases thanks to the FDA's August approval of GlaxoSmithKline's Hiberix as a booster dose for children ages 15 months to 4 years, the AAFP has adopted the CDC's recommendation that physicians recall children who have not received a booster dose. (Source: AAFP Health of the Public)
Source: AAFP Health of the Public - September 28, 2009 Category: Primary Care Source Type: news

Licensure of a Haemophilus influenzae type b (Hib) vaccine (Hiberix) and updated recommendations for use of Hib vaccine.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report summarizes the indications for Hiberix use and provides guidance on Hib booster dose administration based on increasing vaccine supplies. Vaccination recommendations in this report update the previous advisory on Hib booster administration (June 26, 2009), which advised that children with deferred booster doses receive it at the next regularly scheduled visit. Vaccination providers are now recommended to begin recall of children in need of the booster dose when feasible and monovalent Hib vaccine supply in the office is adequate. PMID: 19763078 [PubMed - indexed for MEDLINE] (Source: MMWR Morb Mortal Wkl...)
Source: MMWR Morb Mortal Wkl... - September 17, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals

Licensure of a Haemophilus influenzae Type b (Hib) Vaccine (Hiberix) and Updated Recommendations for Use of Hib VaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - September 17, 2009 Category: American Health Source Type: organizations

Phenotypic and genetic characterizations of nontypeable Haemophilus influenzae isolates in a hospital in ThailandEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Since the introduction of the Haemophilus influenzae serotype b (Hib) vaccine, the decline in invasive Hib disease and the relative increase in nontypeable H. influenzae (NTHi) infections has been well documented in many parts of the world. In South East Asia, however, Hib disease burden is controversial and has been a matter of debate. The decision on the use of Hib vaccine thus awaits for more data on the true incidence of Hib disease. In Thailand where Hib vaccine has not been nationally introduced, H. influenzae remains one of the most important respiratory pathogens. While studies regarding the infections caused by H...
Source: Journal of Infection - September 2, 2009 Category: Infectious Diseases Authors: Duangkamol Kunthalert, Parichart (Kamklon) Thunyathada, Sumalee Pruksakorn Tags: Regular Letters Source Type: journals

Approved Hib Booster Vaccine Shores Up SupplyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Food and Drug Administration has approved a new Haemophilus influenzae type b (Hib) vaccine for use as a booster dose in children aged 15 months through 4 years, providing another option for children whose boosters were deferred as a result of the nationwide Hib vaccine shortage that began almost 2 years ago, the agency announced last month. (Source: Family Practice News)
Source: Family Practice News - August 31, 2009 Category: Primary Care Authors: ELIZABETH MECHCATIE Tags: News Source Type: news

New Hib Booster Vaccine Shores Up SupplyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The Food and Drug Administration has approved a new Haemophilus influenzae type b (Hib) vaccine for use as a booster dose in children aged 15 months through 4 years, providing another option for children whose boosters were deferred as a result of the nationwide Hib vaccine shortage that began almost 2 years ago. (Source: Pediatric News)
Source: Pediatric News - August 31, 2009 Category: Journals (General) Authors: ELIZABETH MECHCATIE Tags: Infectious Diseases Source Type: news

IgG responses after booster vaccination with different pertussis vaccines in Dutch children 4 years of age: Effect of vaccine antigen content.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study shows that a booster vaccine with high pertussis antigen concentrations induces higher antibody levels than a low antigen containing vaccine. In children primed with the Dutch DTwP-IPV-Hib vaccine we suggest to administer a booster vaccine containing high pertussis antigens to optimize IgG responses. The pertussis vaccination history has to be taken into account in decisions on changes in pertussis vaccination policy. PMID: 19729085 [PubMed - as supplied by publisher] (Source: Vaccine)
Source: Vaccine - August 30, 2009 Category: Allergy & Immunology Authors: Hendrikx LH, Berbers GA, Veenhoven RH, Sanders EA, Buisman AM Tags: Vaccine Source Type: journals

No Evidence That Combined DTP-HBV-Hib Vaccine Works BetterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
07/21/2009, Cochrane Library, There is no evidence that giving infants a combination vaccine for diphtheria (D), tetanus (T), pertussis (P), hepatitis B (HBV), and Haemophilus influenza type B (Hib) protects them as effectively as separate vaccines, according to the results of a new Cochrane review. (Source: Health Behavior News Service)
Source: Health Behavior News Service - August 28, 2009 Category: Consumer Health News Source Type: news

National, state, and local area vaccination coverage among children aged 19-35 months - United States, 2008.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report describes the 2008 NIS coverage estimates for this series and individual vaccines, 7-valent pneumococcal conjugate vaccine (PCV7), >or=2 doses of hepatitis A vaccine (HepA), and hepatitis B vaccination received in the first 3 days of life (HepB birth dose) among children born during January 2005-June 2007. In 2008, 4:3:1:3:3:1 series coverage was 76.1%, compared with 77.4% in 2007; >or=90% coverage was maintained for all recommended series vaccines, except >or=4 doses of diphtheria, tetanus, and acellular pertussis (DTaP) vaccine. Coverage with >or=3 doses of Haemophilus influenzae type b vaccine (H...
Source: MMWR Morb Mortal Wkl... - August 27, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals

New GSK Product Should Help Alleviate Hib Vaccine ShortageEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The nation's supply of Haemophilus influenzae type b, or Hib, vaccine should see a much-needed upsurge in the coming weeks, thanks to the Aug. 19 FDA approval of GlaxoSmithKline's Hiberix as a booster dose for children ages 15 months to 4 years. (Source: AAFP Clinical Care and Research)
Source: AAFP Clinical Care and Research - August 26, 2009 Category: Primary Care Source Type: news

FDA Approves Glaxosmithkline's Hib Vaccine, Hiberix(R)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In response to a U.S. shortage of a vaccine to protect infants from Haemophilus influenzae type b (Hib), GlaxoSmithKline (NYSE: GSK) has received accelerated approval from the FDA (Food and Drug Administration) for Hiberix® [Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate)] as a booster dose in children 15 months through four years of age. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 21, 2009 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

New Hib Vaccine Granted Accelerated ApprovalEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: New Hib Vaccine Granted Accelerated ApprovalCategory: Health NewsCreated: 8/20/2009 2:10:00 PMLast Editorial Review: 8/21/2009 (Source: MedicineNet Hepatitis C General)
Source: MedicineNet Hepatitis C General - August 21, 2009 Category: Infectious Diseases Source Type: consumer

New Hib Vaccine Granted Accelerated ApprovalEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Title: New Hib Vaccine Granted Accelerated ApprovalCategory: Health NewsCreated: 8/20/2009 2:10:00 PMLast Editorial Review: 8/21/2009 (Source: MedicineNet Kids Health General)
Source: MedicineNet Kids Health General - August 21, 2009 Category: Pediatrics Source Type: consumer

FDA Okays Vaccine for Hib BoosterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
WASHINGTON (MedPage Today) -- The FDA has approved a new Haemophilus influenzae type b (Hib) vaccine -- Hiberix -- for use as a booster dose from age 15 months through 4 years. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - August 20, 2009 Category: Infectious Diseases Source Type: news

Accelerated FDA Approval of New Hib Vaccine Boosts Nationwide SupplyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The FDA has granted accelerated approval for a Haemophilus influenza type b vaccine as a booster dose for children aged 15 months through 4 years. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 20, 2009 Category: Consumer Health News Tags: Infectious Diseases Source Type: news

FDA Approves GSK's Hib Vaccine, HiberixEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PHILADELPHIA, Aug. 19 /PRNewswire-FirstCall/ -- In response to a U.S. shortage of a vaccine to protect infants from Haemophilus influenzae type b (Hib), GlaxoSmithKline (NYSE:GSK) has received accelerated approval from the FDA (Food and Drug... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - August 20, 2009 Category: Drugs & Pharmacology Source Type: news

Accelerated Approval Of Hiberix To Help Sustain Adequate Vaccine SupplyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The U.S. Food and Drug Administration approved Hiberix, a Haemophilus influenzae Type b (Hib) vaccine, as a booster dose for children 15 months through 4 years old. Hiberix is manufactured by GlaxoSmithKline, with U.S. headquarters in Research Triangle Park, N.C. and Philadelphia. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 20, 2009 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

Accelerated Approval of Hiberix to Help Sustain Adequate Vaccine SupplyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The U.S. Food and Drug Administration today approved Hiberix, a Haemophilus influenzae Type b (Hib) vaccine, as a booster dose for children 15 months through 4 years old. Hiberix is manufactured by GlaxoSmithKline, with U.S. headquarters in Research Triangle Park, N.C. and Philadelphia. (Source: Food and Drug Administration)
Source: Food and Drug Administration - August 19, 2009 Category: American Health Source Type: organizations

Jury out on Added Benefit of Combined DTP-HBV-HIB VaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
It is unclear whether the combined diphtheria-tetanus-pertussis, hepatitis B, and Haemophilus influenzae type B (DTP-HBV-HIB) vaccine is as effective as the separate DTP-HBV and HIB vaccine, researchers say. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 6, 2009 Category: Consumer Health News Tags: Allergy & Clinical Immunology Source Type: news

Jury out on benefit of infant vaccine comboEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
NEW YORK (Reuters Health) - It is unclear whether giving infants a combination vaccine for diphtheria-tetanus-pertussis, hepatitis B, and Haemophilus influenzae type B (DTP-HBV-HIB) protects them as effectively as separate DTP-HBV and HIB vaccines, a review of published studies indicates. (Source: Reuters: Health)
Source: Reuters: Health - August 5, 2009 Category: Consumer Health News Tags: healthNews Source Type: news

Combined vs separately administered vaccines for prevention of diphtheria tetanus pertussis HBV and HIBEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Published July 2009Plain language conclusion: Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B in healthy infants up to two years of age (Source: Gastroenterology and Liver Diseases Specialist Library - Liver)
Source: Gastroenterology and Liver Diseases Specialist Library - Liver - July 22, 2009 Category: Gastroenterology Source Type: organizations

Combined vs separately administered vaccines for prevention of diphtheria tetanus pertussis HBV and HIBEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Published July 2009Plain language conclusion: Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B in healthy infants up to two years of age (Source: Gastroenterology and Liver Diseases Specialist Library - Prevention)
Source: Gastroenterology and Liver Diseases Specialist Library - Prevention - July 22, 2009 Category: Gastroenterology Source Type: organizations

No Evidence That Combined DTP-HBV-Hib Vaccine Works BetterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
There is no evidence that giving infants a combination vaccine for diphtheria (D), tetanus (T), pertussis (P), hepatitis B (HBV), and Haemophilus influenza type B (Hib) protects them as effectively as separate vaccines, according to the results of a new Cochrane review. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 22, 2009 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Long‐Term Immunological Follow‐Up of Children with Haemophilus influenzae Serotype b Vaccine Failure in the United KingdomEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to determine Hib antibody concentrations in children several years after infection and to identify risk factors for low antibody concentrations. Methods. The families of children from the United Kingdom who developed invasive Hib disease after prior immunization with Hib conjugate vaccine (i.e., Hib vaccine failure) from October 1992 through December 2005 were asked to complete a questionnaire. A blood sample was also obtained from each child. Results. Of 323 families approached, 260 (80.5%) returned a completed questionnaire, and 175 (54.2%) children provided a blood sample. The media...
Source: Clinical Infectious Diseases Latest Issue - July 6, 2009 Category: Infectious Diseases Tags: article MAJOR ARTICLE Source Type: journals

CDC Reinstates Hib Booster Dose for 12- to 15-month-oldsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
After more than a year and a half of deferrals, the booster dose of Haemophilus influenzae type b, or Hib, vaccine should again be considered a routine part of the childhood immunization schedule. The CDC -- in consultation with its Advisory Committee on Immunization Practices, or ACIP, the AAFP and the American Academy of Pediatrics -- is recommending that physicians immediately reinstate the Hib booster dose for children ages 12-15 months who have completed the three-dose primary series. (Source: AAFP Clinical Care and Research)
Source: AAFP Clinical Care and Research - July 1, 2009 Category: Primary Care Source Type: news

Hib Vaccine Booster Dose ReinstatedEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ATLANTA — Physicians should resume giving booster vaccinations for Haemophilus influenzae type b to children aged 12–15 months at routine visits, the Centers for Disease Control and Prevention recommended. (Source: Pediatric News)
Source: Pediatric News - June 30, 2009 Category: Journals (General) Authors: MIRIAM E. TUCKER Tags: News Source Type: news

Booster HiB vaccine reinstituted in select age groupsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Booster shots of a vaccine guarding against bacterial meningitis have been reinstated for children by the CDC. (Source: Modern Medicine)
Source: Modern Medicine - June 28, 2009 Category: Journals (General) Source Type: info

Booster HiB vaccine reinstituted in select age groupsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Booster shots of a vaccine guarding against bacterial meningitis have been reinstated for children by the CDC. (Source: Modern Medicine Contemporary Pediatrics)
Source: Modern Medicine Contemporary Pediatrics - June 28, 2009 Category: Pediatrics Source Type: info

Updated Recommendations for Use of Haemophilus influenzae Type b (Hib) Vaccine: Reinstatement of the Booster Dose at Ages 12--15 MonthsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - June 26, 2009 Category: American Health Source Type: organizations

Sanofi Pasteur Responds To Nation's Need For Hib Vaccine With Increased SupplyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sanofi Pasteur, the vaccines division of the sanofi-aventis Group (EURONEXT: SAN and NYSE: SNY), announced that the company has been able to increase the supply of its Hib-containing vaccines to enable the return to a full series of vaccinations for U.S. children. Based on the increased supply, on July 1, the U.S. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 26, 2009 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Updated recommendations for use of Haemophilus influenzae type b (Hib) vaccine: reinstatement of the booster dose at ages 12-15 months.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: On December 13, 2007, certain lots of Haemophilus influenzae type b (Hib) vaccine marketed as PedvaxHIB (monovalent Hib vaccine) and Comvax (Hib-HepB vaccine), and manufactured by Merck & Co., Inc., were recalled voluntarily, and the company temporarily suspended production of these vaccines. To conserve the limited supply of Hib-containing vaccines, CDC, in consultation with the Advisory Committee on Immunization Practices (ACIP), the American Academy of Family Physicians (AAFP), and the American Academy of Pediatrics (AAP), on December 18, 2007, recommended that vaccination providers temporarily defer ...
Source: MMWR Morb Mortal Wkl... - June 25, 2009 Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: journals

CDC Reinstates Recommendation for Haemophilus Vaccine Booster (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ATLANTA (MedPage Today) -- With a shortage of Haemophilus influenzae type b (Hib) vaccine now relieved, the CDC is again recommending that most children receive a booster dose at 12 to 15 months of age. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - June 25, 2009 Category: Infectious Diseases Source Type: news

CDC to reinstate booster shots of HiB vaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CHICAGO (Reuters) - The U.S. Centers for Disease Control and Prevention said on Thursday it plans to reinstate booster shoots of a vaccine that protects children against bacterial meningitis. (Source: Reuters: Health)
Source: Reuters: Health - June 25, 2009 Category: Consumer Health News Tags: healthNews Source Type: news

CDC to reinstate booster shots for HiB vaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CHICAGO (Reuters) - The U.S. Centers for Disease Control and Prevention said on Thursday it plans to reinstate booster shoots of a vaccine that protects babies and toddlers against bacterial meningitis. (Source: Reuters: Health)
Source: Reuters: Health - June 25, 2009 Category: Consumer Health News Tags: healthNews Source Type: news

CDC to Reinstate Booster Shots of HiB VaccineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The U.S. Centers for Disease Control and Prevention said on Thursday it plans to reinstate booster shoots of a vaccine that protects children against bacterial meningitis. Source: Reuters Health Related MedlinePlus Topic: Childhood Immunization (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - June 25, 2009 Category: Consumer Health News Source Type: consumer

Invasive Haemophilus influenzae Type b Disease in Five Young Children—Minnesota, 2008Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
[Centers for Disease Control and Prevention. Invasive Haemophilus influenzae type b disease in five young children—Minnesota, 2008. MMWR Morb Mortal Wkly Rep. 2009;58:58-60.] In 2008, 5 children younger than 5 years were reported to the Minnesota Department of Health (MDH) with invasive Haemophilus influenzae type b (Hib) disease; one child died. Only 1 of the children had completed the primary Hib immunization series; 3 had received no doses of Hib-containing vaccine. The 5 Hib cases are the largest number among children younger than 5 years reported from Minnesota since 1992. The cases occurred during a Hib vaccine re...
Source: Annals of Emergency Medicine - June 25, 2009 Category: Emergency Medicine Authors: Centers for Disease Control and Prevention Tags: Infectious Disease Source Type: journals

CommentaryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
[Ann Emerg Med. 2009;54:85.] Historically, emergency physicians were well acquainted with invasive disease caused by Hib. Today, most physicians in training will finish residency never having seen a child present with complications caused by Hib. Since 1990, a conjugate Hib vaccine has decreased the annual incidence of invasive disease to near nondetectable levels. However, the above report describes an unusually high frequency of cases identified in 2008 in Minnesota, mainly among underimmunized children. (Source: Annals of Emergency Medicine)
Source: Annals of Emergency Medicine - June 25, 2009 Category: Emergency Medicine Authors: Lucas D. Karaelias, Sukhjit S. Takhar Tags: Infectious Disease Source Type: journals

Sanofi Pasteur Responds To Nation's Need For Hib Vaccine With Increased SupplyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Sanofi Pasteur, the vaccines division of the sanofi-aventis Group (EURONEXT: SAN and NYSE: SNY), announced today that the company has been able to increase the supply of its Hib-containing vaccines to enable the return to a full series of vaccinations for U.S. children. (Source: Pharmaceutical Online News)
Source: Pharmaceutical Online News - June 25, 2009 Category: Pharmaceuticals Source Type: news

Clinical characteristics of Haemophilus influenzae meningitis in Denmark in the post-vaccination eraEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, meningitis caused by Hib has been infrequent in Denmark after introduction of the Hib vaccine in the childhood vaccination programme, and no increase in meningitis cases due to non-b type H. influenzae has been observed. Cases with H. influenzae meningitis frequently had an otogenic focus, with low risk of an unfavourable outcome. (Source: Clinical Microbiology and Infection)
Source: Clinical Microbiology and Infection - June 21, 2009 Category: Microbiology Authors: T.I. Pedersen, M. Howitz, C. Østergaard Source Type: journals

Humoral immunity to diphtheria, tetanus, measles, and hemophilus influenzae type b in children with acute lymphoblastic leukemia and response to re-vaccinationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Loss of immunity to previous vaccination and timing of re-vaccination in children receiving chemotherapy remains controversial. The aim of this study was to investigate the immunity to vaccine preventable diseases in children with acute lymphoblastic leukemia (ALL).Sixty-one patients with ALL and 13 healthy siblings were enrolled. Three study groups included newly diagnosed patients (group 1), patients on maintenance chemotherapy (group 2), and patients that completed chemotherapy (group 3). Blood samples for baseline antibody titers were obtained from all the patients and controls. Patients in group 2 were vaccinated with...
Source: Pediatric Blood and Cancer - June 17, 2009 Category: Cancer & Oncology Authors: Emine Zengin, Nazan Sarper Source Type: journals

Reduction of meningitis and impact on under-5 pneumonia after introducing the Hib vaccine in the Kingdom of Tonga.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Hib vaccine has reduced invasive Hi disease and Hi meningitis in Tonga. The reduction in inpatient pneumonia is more likely a reflection of annual fluctuations in viral pneumonia than of a reduction in Hib pneumonia, but ongoing surveillance is recommended. PMID: 19460264 [PubMed - in process] (Source: Annals of Tropical Paediatrics)
Source: Annals of Tropical Paediatrics - May 31, 2009 Category: Tropical Medicine Authors: Russell FM, Fakakovi T, Paasi S, Ika A, Mulholland EK Tags: Ann Trop Paediatr Source Type: journals

Infants' Pain Response To Immunization Varies Based On Which Vaccine Is FirstEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Infants who receive the pneumococcal conjugate vaccine (PCV) following the combination vaccine for diphtheria, polio, tetanus, pertussis and Haemophilus influenza type b (DPTaP-Hib vaccine) appear to experience less pain than those who are immunized in the opposite order, according to a report in the May issue of Archives of Pediatrics & Adolescent Medicine, a theme issue on vaccines. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 13, 2009 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

The Order Of Vaccine Injections Has An Effect On The PainÂ´s Feedback In InfantsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A report in the May issue of Archives of Pediatrics & Adolescent Medicine indicates that infants who receive the pneumococcal conjugate vaccine (PCV) after being given the grouping vaccine for diphtheria, polio, tetanus, pertussis and Haemophilus influenza type b (DPTaP-Hib vaccine) seem to experience less pain than other infants who are given the vaccinations in the reverse order. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 6, 2009 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news