University of OttawaThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you your search results in order of date.

Pages: 1 2 3

133 records returned

Flibanserin demonstrates efficacy and tolerability in pivotal Phase III Trials in pre-menopausal women with Hypoactive Sexual Desire Disorder (HSDD)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ingelheim/ Germany, 16 November 2009 - Data from pooled, pivotal Phase III clinical trials demonstrate that flibanserin 100mg taken once daily at bedtime significantly increased the number of Satisfying Sexual Events (SSEs) and sexual desire while significantly decreasing the distress associated with Hypoactive Sexual Desire Disorder (HSDD).1 Flibanserin is an investigational compound that is being developed by Boehringer Ingelheim for the treatment of pre-menopausal women with HSDD. HSDD is a medical condition characterised by a decrease in sexual desire associated with marked distress and/or interpersonal difficultie...
Source: Boehringer Ingelheim RSS-Newsfeed - November 16, 2009 Category: Research Source Type: organizations

Ottawa 'star' researcher mourned after H1N1 deathEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A University of Ottawa chemistry professor who died this week after contracting swine flu is being remembered as a scientific star and a devoted family man. (Source: CBC | Health)
Source: CBC | Health - November 13, 2009 Category: Consumer Health News Source Type: news

Ottawa 'star' researcher mourned after dying of H1N1Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A University of Ottawa chemistry professor who died this week after contracting swine flu is being remembered as a scientific star and a devoted family man. (Source: CBC | Health)
Source: CBC | Health - November 13, 2009 Category: Consumer Health News Source Type: news

The Wide-Awake Approach to Dupuytren’s Disease: Fasciectomy under Local Anesthetic with EpinephrineEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The Wide-Awake Approach to Dupuytren's contracture involves fasciectomy under local anesthetic with epinephrine and no tourniquet. The goal of this study is to show that the Wide-Awake Approach produces equivalent outcomes to fasciectomy under general anesthetic with a tourniquet, with fewer risks to the patient. A multicenter retrospective review was conducted on 111 patients with fasciectomies under local or general anesthetic between 2001 and 2007. Data on patient demographics, comorbidities, cost, as well as range of motion was collected and evaluated using Microsoft Excel and SAS. Of 148 finger...
Source: Hand - November 10, 2009 Category: Surgery Tags: Hand Source Type: journals

The transcription factor GATA-2 does not associate with angiographic coronary artery disease in the Ottawa Heart Genomics and Cleveland Clinic GeneBank StudiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The transcription factor GATA2 was reported to associate with coronary artery disease (CAD) in the family-based Genecard sample (Connelly et al. in PLoS Genet 2:e139, 2006). We asked whether GATA2 associates with sporadic cases of CAD in the Ottawa Heart Genomics Study (OHGS) and Cleveland Clinic (CC) populations. We genotyped the lead single nucleotide polymorphism (SNP) from Genecard, rs2713604 which is located in intron 5–6 of GATA2 in 600 CAD cases and 625 controls, as well as a tag SNP rs1573949 (r 2 = 0.87 in Caucasians of European ancestry in Utah from HapMap) in 1,136 cases...
Source: Human Genetics - November 3, 2009 Category: Genetics & Stem Cells Tags: Human Genetics Source Type: journals

Heat balance and cumulative heat storage during exercise performed in the heat in physically active younger and middle-aged menEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract On separate days, eight physically active younger (22 ± 2 years) and eight highly trained middle-aged (45 ± 4 years) men matched for physical fitness and body composition performed 90 min of semi-recumbent cycling at a constant rate of heat production (290 W) followed by 60 min of seated recovery in either a temperate (T, 30°C), warm (W, 35°C) or hot (H, 40°C) ambient condition. Rectal temperature (T re) was measured continuously, while the rate of whole-body heat loss (H L), as well as changes in body heat content (∆H b) was measured simultan...
Source: European Journal of Applied Physiology - November 3, 2009 Category: Physiology Tags: European Journal of Applied Physiology Source Type: journals

Development of a framework for reporting health service models for managing rheumatoid arthritisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The purpose of this study was to develop a framework for reporting health service models for managing rheumatoid arthritis (RA). We conducted a search of the health sciences literature for primary studies that described interventions which aimed to improve the implementation of health services in adults with RA. Thereafter, a nominal group consensus process was used to synthesize the evidence for the development of the reporting framework. Of the 2,033 citations screened, 68 primary studies were included which described 93 health service models for RA. The origin and meaning of the labels given to t...
Source: Clinical Rheumatology - October 28, 2009 Category: Rheumatology Tags: Clinical Rheumatology Source Type: journals

Influence of nonthermal baroreceptor modulation of heat loss responses during uncompensable heat stressEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract We evaluated the hypothesis that with increasing levels of hyperthermia, thermal influences would predominate over nonthermal baroreceptor control of cutaneous vascular conductance (CVC) and local sweat rate (LSR). On separate days, eight male participants were positioned in either an upright seated posture (URS) or a 15° head-down tilt (HDT) posture in a thermoneutral condition and during passive heating, until mean body temperature (T body) increased by 1.5°C. Hemodynamic [heart rate (HR), cardiac output, mean arterial pressure (MAP)] and thermal responses [T re, CVC, LSR] were measured continu...
Source: European Journal of Applied Physiology - October 27, 2009 Category: Physiology Tags: European Journal of Applied Physiology Source Type: journals

Same question, different answers: a comparison of global health assessments using visual analogue scalesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions The EQ-VAS and PG-VAS scores are not interchangeable at the individual level. The EQ-VAS correlated more strongly with disease-specific and health-related quality of life measures, therefore, appears preferable. Content Type Journal ArticleDOI 10.1007/s11136-009-9546-3Authors Mark J. Harrison, The University of Manchester arc Epidemiology Unit Stopford Building, Oxford Road Manchester M13 9PT UKAnnelies Boonen, Maastricht University Medical Center Department of Internal Medicine, Division of Rheumatology P Debyelaan 25 6229 HX Maastricht The NetherlandsPeter Tugwell, University of Ottawa Ca...
Source: Quality of Life Research - October 24, 2009 Category: Health Management Tags: Quality of Life Research Source Type: journals

Innovations in anesthesia education: the development and implementation of a resident rotation for advanced airway management.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Anesthesia training programs must provide residents with the skill sets necessary for safe independent practice in airway management. The changes in the scope and reality of residency training have exposed limitations in the traditional mentoring model of residency training; consequently, many programs have responded by offering sub-specialty rotations. In particular, advanced airway management rotations are being offered increasingly to residents in the Canadian training programs. Considerations and strategies to develop and implement a structured airway management program during anesthesia residency are disc...
Source: Canadian Journal of Anaesthesia - October 21, 2009 Category: Anesthesiology Authors: Crosby E, Lane A Tags: Can J Anaesth Source Type: journals

The effects of vasopressin on acute kidney injury in septic shockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Vasopressin may reduce progression to renal failure and mortality in patients at risk of kidney injury who have septic shock. Content Type Journal ArticleCategory OriginalDOI 10.1007/s00134-009-1687-xAuthors Anthony C. Gordon, Imperial College NHS Trust Intensive Care Unit, Charing Cross Hospital Fulham Palace Road London W6 8RF UKJames A. Russell, University of British Columbia iCAPTURE Centre, St. Paul’s Hospital Vancouver CanadaKeith R. Walley, University of British Columbia iCAPTURE Centre, St. Paul’s Hospital Vancouver CanadaJoel Singer, University of British Columbia Department of ...
Source: Intensive Care Medicine - October 20, 2009 Category: Intensive Care Tags: Intensive Care Medicine Source Type: journals

CHEO RI study uses sophisticated genetic engineering to improve insulin-producing beta cellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Children's Hospital of Eastern Ontario Research Institute) A study to be published today in the leading international journal Cell Metabolism describes how a research group led by Dr. Robert Screaton, who holds the Canada Research Chair in Apoptotic Signaling at the University of Ottawa, used sophisticated genetic engineering to remove or "knock out" the Lkb1 gene from beta cells of laboratory mice. The result was an increase in both the size and number of beta cells, as well as greater amounts of insulin stored and released by the cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 7, 2009 Category: Global & Universal Source Type: news

CHEO RI Study Uses Sophisticated Genetic Engineering to Improve Insulin-Producing Beta CellsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
October 7, 2009 (EurekAlert) - One of the biggest mysteries about diabetes is why specialized cells in the pancreas stop secreting insulin, which the body needs in order to store glucose from food. A team from the Children's Hospital of Eastern Ontario (CHEO) Research Institute has identified a protein that inhibits insulin production in mice - work that offers a new way of understanding, and perhaps of one day treating, both Type 1 and Type 2 diabetes. A study to be published today in the leading international journal Cell Metabolism describes how a research group led by Dr. Robert Screaton, who holds the Canada Resea...
Source: Diabetes News from dLife.com - October 6, 2009 Category: Consumer Health News Authors: dlife Source Type: info

Effects of two glucose ingestion rates on substrate utilization during moderate-intensity shiveringEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, glucose ingestion even at low rates contributes a significant proportion of total heat production during moderate intensity shivering and reduces the utilization of liver-derived glucose but not muscle glycogen. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00421-009-1210-7Authors Denis P. Blondin, University of Ottawa Faculty of Health Sciences, School of Human Kinetics 125 University St. Ottawa ON K1N 6N5 CanadaIsabelle Dépault, University of Ottawa Faculty of Health Sciences, School of Human Kinetics 125 University St. Ottawa ON K1N 6N5 CanadaPascal Imbeault, University of Otta...
Source: European Journal of Applied Physiology - September 24, 2009 Category: Physiology Tags: European Journal of Applied Physiology Source Type: journals

Cognitive decline associated with dementia and type 2 diabetes: the interplay of risk factorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory CommentaryDOI 10.1007/s00125-009-1533-2Authors C. Messier, University of Ottawa School of Psychology 200 Lees Avenue, Room E260J Ottawa ON Canada K1N 6N5M. Gagnon, Riverside Professional Medical Center 1919 Riverside Drive, Room 306 Ottawa ON Canada K1H 1A2 Journal DiabetologiaOnline ISSN 1432-0428Print ISSN 0012-186X (Source: Diabetologia)
Source: Diabetologia - September 24, 2009 Category: Endocrinology Tags: Diabetologia Source Type: journals

Intrathecal antibody production against Epstein-Barr and other neurotropic viruses in pediatric and adult onset multiple sclerosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of this study was to assess the frequency and intensity of intrathecal antibody production against EBV as compared to other neurotropic viruses in pediatric and adult onset MS. In cohorts of 43 childhood, 50 adult onset MS patients, 20 children and 12 adults with other CNS disorders, paired CSF and serum samples were studied. Frequency and intensity of intrathecal antibody production against EBV as compared to measles, rubella, varicella zoster (VZV) and herpes simplex virus (HSV) were analyzed by determination of virus-specific CSF-to-serum Antibody Indices (AI). Intrathecally synthesized EBV antibodies...
Source: Journal of Neurology - August 28, 2009 Category: Neurology Tags: Journal of Neurology Source Type: journals

An Investigation Into The Immune Response To Wheat Offers A Clue To The Elusive Cause Of Type 1 DiabetesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Scientists at the Ottawa Hospital Research Institute and the University of Ottawa have discovered what may be an important clue to the cause of type 1 diabetes. Dr. Fraser Scott and his team tested 42 people with type 1 diabetes and found that nearly half had an abnormal immune response to wheat proteins. The study is published in the August 2009 issue of the journal Diabetes. (Source: Diabetes News From Medical News Today)
Source: Diabetes News From Medical News Today - August 22, 2009 Category: Endocrinology Tags: Diabetes Source Type: news

Type 1 diabetes linked to immune response to wheatEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Ottawa Hospital Research Institute) Scientists at the Ottawa Hospital Research Institute and the University of Ottawa have discovered what may be an important clue to the cause of type 1 diabetes. Dr. Fraser Scott and his team tested 42 people with type 1 diabetes and found that nearly half had an abnormal immune response to wheat proteins. The study is published in the August 2009 issue of the journal Diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2009 Category: Global & Universal Source Type: news

A Clue to the Elusive Cause of Type 1 Diabetes: Ottawa Researchers Investigate Immune Response to WheatEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
August 20, 2009 (OHRI) - Scientists at the Ottawa Hospital Research Institute and the University of Ottawa have discovered what may be an important clue to the cause of type 1 diabetes. Dr. Fraser Scott and his team tested 42 people with type 1 diabetes and found that nearly half had an abnormal immune response to wheat proteins. The study is published in the August 2009 issue of the journal Diabetes. Early in life, the immune system is supposed to learn to attack foreign invaders such as viruses and bacteria, while leaving the body’s own tissues and harmless molecules in the environment alone (including food in the ...
Source: Diabetes News from dLife.com - August 19, 2009 Category: Consumer Health News Authors: dlife Source Type: info

Increased susceptibility to oxidative damage in post-diabetic human myotubesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions/interpretation This is the first report to note that primary myotubes from patients with a history of type 2 diabetes are unable to adapt to a hyperglycaemic–hyperinsulinaemic challenge. We have demonstrated that impaired mitochondrial biogenesis and an inability to manage oxidative stress define a muscle phenotype at risk of obesity-associated type 2 diabetes. Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-009-1480-yAuthors S. R. Costford, University of Ottawa Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine 451 Smyth Road Ottawa ON K1H 8M5 Ca...
Source: Diabetologia - August 15, 2009 Category: Endocrinology Tags: Diabetologia Source Type: journals

Building Nurses' Capacity in Community Health ServicesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This paper describes core processes, components, and insights gained from a research internship offered through the University of Ottawa, Canada. The growing demand for high quality nursing research requires the development and implementation of strategies for enhanced research capacity. A three-month intensive internship was developed as a main feature of a nursing chair held by the first author. The internship was deliberately structured around core processes of providing individual and group mentoring, creating opportunities for experiential education, and strengthening networks with researchers and decision-makers in h...
Source: International Journal of Nursing Education Scholarship - August 12, 2009 Category: Nursing Tags: Research Capacity Source Type: journals

Age dependent T2 changes of bone marrow in pediatric wrist MRIEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Foci of hyperintense bone marrow seen on fluid-sensitive sequences can be seen on MRI of the wrist during childhood even without apparent symptoms. It shows a consistent pattern with maturation: frequency and intensity decrease and there is distal-to-proximal resolution. This may be a normal finding that may represent normal bone remodeling or decreasing hematopoietic marrow and should not be confused with pathological bone marrow edema. Content Type Journal ArticleCategory Scientific ArticleDOI 10.1007/s00256-009-0752-4Authors Nogah Shabshin, Chaim Sheba Medical Center Department of Diagn...
Source: Skeletal Radiology - August 7, 2009 Category: Radiology Tags: Skeletal Radiology Source Type: journals

Two models of raters in a structured oral examination: does it make a difference?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study suggests that although the model of candidate-specific raters was more reliable than the model of station-specific raters for the overall examination, the presence of a halo effect may influence individual examination outcomes. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10459-009-9175-1Authors Claire Touchie, University of Ottawa Division of General Internal Medicine, Department of Medicine Ottawa ON CanadaSusan Humphrey-Murto, University of Ottawa Division of Rheumatology, Department of Medicine Ottawa ON CanadaMartha Ainslie, University of Calgary Division of Respirology, Department ...
Source: Advances in Health Sciences Education - August 6, 2009 Category: Universities & Medical Training Tags: Advances in Health Sciences Education Source Type: journals

Management of patients transferred to the ICU during the conditioning phase of allogeneic hematopoietic stem cell transplantationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s00134-009-1583-4Authors Abdulaziz Hamadah, The Ottawa Hospital Division of Hematology and Blood and Marrow Transplantation General Campus, 501 Smyth Rd Box 704 Ottawa ON K1H 8L6 CanadaSheryl A. McDiarmid, The Ottawa Hospital Division of Hematology and Blood and Marrow Transplantation General Campus, 501 Smyth Rd Box 704 Ottawa ON K1H 8L6 CanadaLothar B. Huebsch, The Ottawa Hospital Division of Hematology and Blood and Marrow Transplantation General Campus, 501 Smyth Rd Box 704 Ottawa ON K1H 8L6 CanadaRakesh Patel, University of Ottawa Division of Critical ...
Source: Intensive Care Medicine - July 30, 2009 Category: Intensive Care Tags: Intensive Care Medicine Source Type: journals

Electrophysiological studies in the rat brain on the basis for aripiprazole augmentation of antidepressants in major depressive disorderEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The present study showed that addition of ARI to an SSRI regimen reverses the inhibitory action of the SSRI on monoaminergic neuronal firing. Content Type Journal ArticleCategory Original InvestigationDOI 10.1007/s00213-009-1611-7Authors Olga Chernoloz, University of Ottawa Institute of Mental Health Research 1145 Carling Avenue Ottawa ON K1Z 7K4 CanadaMostafa El Mansari, University of Ottawa Institute of Mental Health Research 1145 Carling Avenue Ottawa ON K1Z 7K4 CanadaPierre Blier, University of Ottawa Institute of Mental Health Research 1145 Carling Avenue Ottawa ON K1Z 7K4 Canada ...
Source: Psychopharmacology - July 30, 2009 Category: Psychiatry Tags: Psychopharmacology Source Type: journals

Improving The Science Of Systematic Reviews: Introducing The "PRISMA" Statement (Preferred Reporting Items For Systematic Reviews And Meta-Analyses)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
David Moher, from the Ottawa Hospital Research Institute; University of Ottawa, and an international consortium of contributors publish the PRISMA guidelines: a set of tools developed to help authors improve the reporting of systematic reviews and meta-analyses. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 21, 2009 Category: Consumer Health News Tags: Public Health Source Type: news

Salt sensitivity could be in genesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A gene could be responsible for the high blood pressure some people experience after eating high quantities of salt, say researchers at the University of Ottawa Heart Institute. (Source: CBC | Health)
Source: CBC | Health - July 13, 2009 Category: Consumer Health News Source Type: news

Resident training in minimally invasive surgery: a survey of Canadian department and division chairsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion The chairs’ opinion on the most effective MIS teaching method for residents is basic MIS cases followed by laparoscopic virtual reality simulators. The majority of academic institutions plan to add laparoscopic virtual reality simulators to the curriculum in the next 5 years. Content Type Journal ArticleDOI 10.1007/s00464-009-0611-3Authors Beverley Chan, University of Ottawa Division of General Surgery, Minimally Invasive Surgery Research Group, The Ottawa Hospital 501 Smyth Rd, CCW Rm 1617 Ottawa ON K1H 8L6 CanadaGuillaume Martel, University of Ottawa Division of General Surgery, Mi...
Source: Surgical Endoscopy - July 9, 2009 Category: Surgery Tags: Surgical Endoscopy Source Type: journals

Combination antibiotic susceptibility of biofilm-grown Burkholderia cepacia and Pseudomonas aeruginosa isolated from patients with pulmonary exacerbations of cystic fibrosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study identified potentially effective antibiotic combinations to guide the empirical treatment of CF pulmonary exacerbations. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s10096-009-0774-9Authors L. Dales, University of Ottawa The Ottawa Health Research Institute Ottawa ON CanadaW. Ferris, Children’s Hospital of Eastern Ontario Ottawa ON CanadaK. Vandemheen, University of Ottawa The Ottawa Health Research Institute Ottawa ON CanadaS. D. Aaron, University of Ottawa The Ottawa Health Research Institute Ottawa ON Canada Journal European Journal of Clinical Microbiology & Infectious Disease...
Source: European Journal of Clinical Microbiology & Infectious Diseases - July 6, 2009 Category: Microbiology Tags: European Journal of Clinical Microbiology & Infectious Diseases Source Type: journals

Genomic view of factors leading to plaque instabilityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract The manifestations of coronary artery disease are varied. They all arise as a consequence of the deposition of atherosclerotic plaque within the vessel wall. The most feared sequela of coronary artery disease is sudden and unexpected death in the ostensibly healthy patient. Plaque rupture of hemodynamically insignificant atherosclerotic plaques and ensuing thrombosis is likely responsible for a large proportion of such deaths. Identifying populations at increased risk for sudden death would represent a major advance. Such screening is contingent upon identification of DNA sequence variants that pred...
Source: Current Cardiology Reports - July 1, 2009 Category: Cardiology Tags: Current Cardiology Reports Source Type: journals

An Automated Computerized Auscultation and Diagnostic System for Pulmonary DiseasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Respiratory sounds are of significance as they provide valuable information on the health of the respiratory system. Sounds emanating from the respiratory system are uneven, and vary significantly from one individual to another and for the same individual over time. In and of themselves they are not a direct proof of an ailment, but rather an inference that one exists. Auscultation diagnosis is an art/skill that is acquired and honed by practice; hence it is common to seek confirmation using invasive and potentially harmful imaging diagnosis techniques like X-rays. This research focuses on developin...
Source: Journal of Medical Systems - June 26, 2009 Category: Information Technology Tags: Journal of Medical Systems Source Type: journals

The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohortsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: These results suggest that the INSIG2 rs7566605 variant does not play a major role in determining obesity risk in a racially and ethnically diverse sample of 24,722 individuals from four cohorts. (Source: BMC Medical Genetics - Latest articles)
Source: BMC Medical Genetics - Latest articles - June 11, 2009 Category: Genetics & Stem Cells Authors: Jan BresslerMyriam FornageCraig HanisWen Hong Linda KaoCora LewisRuth McPhersonRobert DentThomas MosleyLen PennacchioEric Boerwinkle Source Type: journals

Iliac bone histomorphometry in children with newly diagnosed inflammatory bowel diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Our results indicate that young patients manifest a mild cortical bone deficit at the iliac crest and slow trabecular bone turnover even at diagnosis, in the setting of IBD. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-0969-zAuthors L. M. Ward, University of Ottawa Department of Pediatrics, Children’s Hospital of Eastern Ontario Ottawa Ontario CanadaF. Rauch, McGill University Genetics Unit, Shriners Hospital for Children Montréal Quebec CanadaM. A. Matzinger, University of Ottawa Department of Pediatrics, Children’s Hospital of Eastern Ontario Ottawa Ont...
Source: Osteoporosis International - June 6, 2009 Category: Orthopaedics Tags: Osteoporosis International Source Type: journals

New Way To Enhance Stem Cells To Stimulate Muscle Regeneration Discovered By Ottawa ScientistsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Scientists at the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa have discovered a powerful new way to stimulate muscle regeneration, paving the way for new treatments for debilitating conditions such as muscular dystrophy. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 6, 2009 Category: Consumer Health News Tags: Muscular Dystrophy / ALS Source Type: news

Lower limb muscle activity and kinematics of an unanticipated cutting manoeuvre: a gender comparisonEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract This investigation compared the amplitude and the timing of the muscle activity of the lower limb, as well as the three-dimensional kinematics of the hip, knee and ankle joints, of male and female elite soccer players performing an unanticipated cutting manoeuvre. These data were recorded for 15 female and 15 male participants for five successful cutting manoeuvres. For this manoeuvre to be performed in an unanticipated manner, the participants were instructed to execute one of three tasks, which were signalled to them with a target board composed of three different coloured lights. Female participa...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - June 4, 2009 Category: Orthopaedics Tags: Knee Surgery, Sports Traumatology, Arthroscopy Source Type: journals

The brain renin-angiotensin-aldosterone system: A major mechanism for sympathetic hyperactivity and left ventricular remodeling and dysfunction after myocardial infarctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Following a myocardial infarction (MI), increases in plasma angiotensin II may activate central nervous system (CNS) pathways and thereby peripheral mechanisms (eg, sympathetic activity and the circulating/cardiac renin-angiotensin-aldosterone system [RAAS]). Plasma angiotensin II may directly activate CNS pathways through the subfornical organ and chronically enhance activity by way of a neuromodulatory system. The latter involves an increase in CNS aldosterone-causing “ouabain” release (eg, from magnocellular neurons of the supraoptic and paraventricular nuclei). “Ouabain” may lower membra...
Source: Current Heart Failure Reports - May 31, 2009 Category: Cardiology Tags: Current Heart Failure Reports Source Type: journals

Government of Canada Recognizes Excellence in Health Care during National Nursing WeekEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To mark National Nursing Week, the Honourable Leona Aglukkaq, Minister of Health, met today with nurses on duty at the University of Ottawa Heart Institute. (Source: Government of Canada News - Health Canada)
Source: Government of Canada News - Health Canada - May 12, 2009 Category: American Health Source Type: organizations

Pathology and new players in the pathogenesis of brain edemaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Brain edema continues to be a major cause of mortality after diverse types of brain pathologies such as major cerebral infarcts, hemorrhages, trauma, infections and tumors. The classification of edema into vasogenic, cytotoxic, hydrocephalic and osmotic has stood the test of time although it is recognized that in most clinical situations there is a combination of different types of edema during the course of the disease. Basic information about the types of edema is provided for better understanding of the expression pattern of some of the newer molecules implicated in the pathogenesis of brain edem...
Source: Acta Neuropathologica - April 30, 2009 Category: Neurology Tags: Acta Neuropathologica Source Type: journals

Learning from the learning curve in total hip resurfacing: a radiographic analysisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In total hip resurfacing one should recognize the presence of a learning curve. This learning curve appears to be acceptable and a reproducible optimal implant positioning can be achieved quickly. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-009-0875-zAuthors Suzanne Witjes, Rijnstate Hospital Department of Surgery and Orthopaedics P.O. Box 9555 6800 TA Arnhem The NetherlandsJosé M. H. Smolders, Rijnstate Hospital Department of Surgery and Orthopaedics P.O. Box 9555 6800 TA Arnhem The NetherlandsPaul E. Beaulé, University of Ottawa Medical School Ottawa ON Can...
Source: Archives of Orthopaedic and Trauma Surgery - April 21, 2009 Category: Orthopaedics Tags: Archives of Orthopaedic and Trauma Surgery Source Type: journals

Creating a genetic risk score for coronary artery diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Coronary artery disease (CAD) and its sequelae represent a significant health burden. Over the past two decades, numerous studies have attempted to link DNA sequence variation with the risk of CAD and related phenotypes. There has been significant evolution in technology from the early linkage studies within kindreds, and now we are able to use high-density genotyping to facilitate large-scale genome-wide association studies. The first novel genetic risk factor for CAD, 9p21.3, has been confirmed, and other loci are awaiting replication studies. The relative importance of each locus from a global st...
Source: Current Atherosclerosis Reports - April 21, 2009 Category: Cardiology Tags: Current Atherosclerosis Reports Source Type: journals

University Of Ottawa Heart Institute Is North America's First Clinical Site For Ultra-sophisticated X-RayEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The University of Ottawa Heart Institute (UOHI) has installed North America's first dual axis rotational cardiac X-ray for clinical use, allowing physicians to more clearly locate and diagnose blockage in the heart's arteries. The ultra-sophisticated equipment cuts radiation exposure by 33%, reduces X-ray time by a similar amount and offers other benefits. (Source: Cardiovascular / Cardiology News From Medical News Today)
Source: Cardiovascular / Cardiology News From Medical News Today - April 17, 2009 Category: Cardiology Tags: MRI / PET / Ultrasound Source Type: news

Canada Should Pass Bill That Would Expedite Export Of Low-Cost Drugs For HIV, Other Diseases, Opinion Piece SaysEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
"For many years, countries such as Canada have avoided the uncomfortable truth that millions are dying in the developing world due partly to legal barriers that render access to medicines unaffordable," Michael Geist, chair of Internet and E-commerce law at the University of Ottawa, writes in a Tor (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 16, 2009 Category: Consumer Health News Tags: HIV / AIDS Source Type: news

Global health network available in Canada thanks to U of OttawaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Canadians are now able to research their health questions through a global online health network with a little help from the University of Ottawa. (Source: CBC | Health)
Source: CBC | Health - April 15, 2009 Category: Consumer Health News Source Type: news

Resident Evaluations: The Use of Daily Evaluation Forms in Rheumatology Ambulatory Care.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The use of daily evaluation forms is feasible and provides very good reliability. Use of the evaluation forms increases feedback to residents on their performance. The forms were well received by faculty and residents. PMID: 19332624 [PubMed - as supplied by publisher] (Source: J Rheumatol)
Source: J Rheumatol - March 30, 2009 Category: Rheumatology Authors: Humphrey-Murto S, Khalidi N, Smith CD, Kaminska E, Touchie C, Keely E, Wood TJ Tags: J Rheumatol Source Type: journals

Quails get super fit by simply eating omega-3 dietEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(The Company of Biologists) Semi-palmated sandpipers migrate over thousands of miles, but how do they build up for the ultramarathon? By simply eating a diet rich in omega-3 fatty acids says Jean-Michel Weber from the University of Ottawa. Weber fed sedentary bobwhite quails that don't exercise a diet rich in omega-3 fatty acids and found that the birds' fitness improved by up to 90 percent. A diet of omega-3 fatty acids can make birds fit by simply eating. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 27, 2009 Category: Biology Source Type: news

Emotional distress impacts fear of the future among breast cancer survivors not the reverseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Discussion Ongoing fear of the future does not appear to be a necessary condition for the development of stress-response symptoms. Implications for Cancer Survivors: Future studies need to explore the role of distressing emotions in the development and exacerbation of fear of the future among cancer survivors. Content Type Journal ArticleDOI 10.1007/s11764-009-0082-5Authors Sophie Lebel, University of Ottawa School of Psychology 11 Marie Curie room 515 Ottawa ON Canada K1N 6N5Zeev Rosberger, Sir Mortimer B. Davis-Jewish General Hospital Montreal QC CanadaLinda Edgar, Sir Mortimer B. Davis-Jewish Gener...
Source: Journal of Cancer Survivorship - March 26, 2009 Category: Cancer & Oncology Tags: Journal of Cancer Survivorship Source Type: journals

Ethics and the Compensation of Immigrant Workers for Work-Related Injuries and IllnessesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract This paper examines the compensation process for work-related injuries and illnesses by assessing the trajectories of a sample of immigrant and non-immigrant workers (n = 104) in Montreal. Workers were interviewed to analyze the complexity associated with the compensation process. Experts specialized in compensation issues assessed the difficulty of the interviewees’ compensation process. Immigrant workers faced greater difficulties with medical, legal, and administrative issues than non-immigrants did. While immigrant workers’ claim forms tended to be written more often by employers o...
Source: Journal of Immigrant and Minority Health - March 24, 2009 Category: Global & Universal Tags: Journal of Immigrant and Minority Health Source Type: journals

A Tree-Based Decision Model to Support Prediction of the Severity of Asthma Exacerbations in ChildrenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract This paper describes the development of a tree-based decision model to predict the severity of pediatric asthma exacerbations in the emergency department (ED) at 2 h following triage. The model was constructed from retrospective patient data abstracted from the ED charts. The original data was preprocessed to eliminate questionable patient records and to normalize values of age-dependent clinical attributes. The model uses attributes routinely collected in the ED and provides predictions even for incomplete observations. Its performance was verified on independent validating data (split-sample ...
Source: Journal of Medical Systems - March 11, 2009 Category: Information Technology Tags: Journal of Medical Systems Source Type: journals