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Alefacept for Severe Alopecia Areata: A Randomized, Double-blind, Placebo-Controlled Study [Study]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Alefacept is ineffective for the treatment of severe AA. (Source: Archives of Dermatology)
Source: Archives of Dermatology - November 16, 2009 Category: Dermatology Authors: Strober, B. E., Menon, K., McMichael, A., Hordinsky, M., Krueger, G., Panko, J., Siu, K., Lustgarten, J. L., Ross, E. K., Shapiro, J. Tags: Dermatology, Dermatologic Disorders, Alopecia, Hair Disorders, Randomized Controlled Trial, Drug Therapy, Drug Therapy, Other Study Source Type: journals

Attitudes of dermatologists in the southeastern United States regarding treatment of alopecia areata: a cross-sectional survey study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Dermatologists' treatment of AA is inconsistent. A stronger evidence base will provide more consistent treatment options. (Source: BMC Dermatology)
Source: BMC Dermatology - November 12, 2009 Category: Dermatology Authors: Niyati MukherjeeDean MorrellMadeleine DuvicPaul StewartLowell Goldsmith Source Type: journals

Topical diphencyprone immunotherapy for cutaneous metastatic melanomaEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Topical immunotherapy with contact sensitizers for metastatic melanoma was first reported more than 30 years ago. Diphencyprone (DPCP) immunotherapy is frequently used to treat cutaneous warts and alopecia areata, and we have previously reported the use of DPCP as a single agent to successfully treat extensive, radiotherapy-resistant melanoma metastases on the scalp. We now report DPCP treatment of a further six patients with cutaneous metastatic melanoma. Of seven patients treated with DPCP thus far, four have demonstrated complete responses of their cutaneous lesions and three have had partial responses. The treatment wa...
Source: Australasian Journal of Dermatology - November 4, 2009 Category: Dermatology Authors: Diona L Damian, Kerwin F Shannon, Robyn P Saw, John F Thompson Tags: CASE REPORTS AND SMALL CASE SERIES Source Type: journals

Photodynamic therapy with methyl 5-aminolevulinate acid combined with microneedle treatment in patients with extensive alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - November 3, 2009 Category: Dermatology Authors: J. W. Lee, K. H. Yoo, B. J. Kim, M. N. Kim Source Type: journals

Four Genes Linked to Alopecia Areata DiscoveredEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New genetic research is yielding some important clues into the puzzling condition of alopecia areata, Dr. Maria Hordinsky reported at the women's and pediatric dermatology seminar sponsored by Skin Disease Education Foundation (SDEF). (Source: Skin and Allergy News)
Source: Skin and Allergy News - November 1, 2009 Category: Dermatology Authors: ROBERT FINN Tags: Hair & Nails Source Type: journals

Topical diphencyprone immunotherapy for cutaneous metastatic melanoma.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Topical immunotherapy with contact sensitizers for metastatic melanoma was first reported more than 30 years ago. Diphencyprone (DPCP) immunotherapy is frequently used to treat cutaneous warts and alopecia areata, and we have previously reported the use of DPCP as a single agent to successfully treat extensive, radiotherapy-resistant melanoma metastases on the scalp. We now report DPCP treatment of a further six patients with cutaneous metastatic melanoma. Of seven patients treated with DPCP thus far, four have demonstrated complete responses of their cutaneous lesions and three have had partial responses. The treatmen...
Source: The Australasian Journal of Dermatology - November 1, 2009 Category: Dermatology Authors: Damian DL, Shannon KF, Saw RP, Thompson JF Tags: Australas J Dermatol Source Type: journals

Serum T helper 1 cytokine levels are greater in patients with alopecia areata regardless of severity or atopyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Increased Th1 serum cytokines (IL-2, IL-12 and interferon-[gamma]) and IL-1ra levels are associated with AA regardless of disease severity or the presence of atopy. (Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: N. Barahmani, A. Lopez, D. Babu, M. Hernandez, S. E. Donely, M. Duvic Source Type: journals

Coudability hairs: a revisited sign of alopecia areata assessed by trichoscopyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Coudability hairs, more closely perceived by trichoscopy, are useful-markers for disease activity in AA and provide a surrogate-marker for the hair-pull test. (Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - October 22, 2009 Category: Dermatology Authors: S. Inui, T. Nakajima, S. Itami Source Type: journals

STUDY: Practical Guidelines for Evaluation of Loose Anagen Hair SyndromeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Loose anagen hair syndrome is a common nonscarring alopecia in young girls with a history of sparse or fine hair. Before ordering extensive blood testing in young girls with diffusely thin hair, it is important to perform a hair-pull test, as a trichogram can be instrumental in the confirmation of a diagnosis of LAHS. (Source: Archives of Dermatology)
Source: Archives of Dermatology - October 19, 2009 Category: Dermatology Authors: Cantatore-Francis, J. L., Orlow, S. J. Tags: Dermatology, Dermatologic Disorders, Alopecia, Pediatrics, Pediatrics, Other, Hair Disorders, Dermatologic Disorders, Other Study Source Type: journals

Practical Guidelines for Evaluation of Loose Anagen Hair Syndrome [Study]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Loose anagen hair syndrome is a common nonscarring alopecia in young girls with a history of sparse or fine hair. Before ordering extensive blood testing in young girls with diffusely thin hair, it is important to perform a hair-pull test, as a trichogram can be instrumental in the confirmation of a diagnosis of LAHS. (Source: Archives of Dermatology)
Source: Archives of Dermatology - October 19, 2009 Category: Dermatology Authors: Cantatore-Francis, J. L., Orlow, S. J. Tags: Dermatology, Dermatologic Disorders, Alopecia, Pediatrics, Pediatrics, Other, Hair Disorders, Dermatologic Disorders, Other Study Source Type: journals

Ocular Alterations In Patients of Alopecia Areata F1000 Ranking "Must Read" and "Changes Clinical Practice"Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Corticosteroid patches for alopecia areata (AA) are significantly associated with cataracts and lens changes. All AA patients alopecia should have a rigorous ophthalmological examination before starting treatment. Faculty of 1000 Medicine (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - October 6, 2009 Category: Opthalmology Tags: Internal Medicine Source Type: info

Increased pachyonychia congenita severity in patients with concurrent keratin and filaggrin mutationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a parent[ndash]child trio in which the mother and the son have PC and the father has IV. Both the mother and the son are carriers for the KRT16 mutation p.Leu132Pro. The son, who is much more severely affected than his mother, in addition carries the heterozygous FLG mutation p.R2447X, which was inherited from the father. This observation suggests that coinheritance of mutations in KRT16 and FLG may aggravate the PC phenotype and that FLG could serve as a genetic modifier in PC. (Source: British Journal of Dermatology)
Source: British Journal of Dermatology - September 27, 2009 Category: Dermatology Authors: R. Gruber, N.J. Wilson, F.J.D. Smith, D. Grabher, L. Steinwender, P.O. Fritsch, M. Schmuth Source Type: journals

’Beacon of hope’: Study finds melanocytes are target in alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Portland, Ore. — A recent study confirms that the numbers of follicular melanocytes are significantly decreased in patients suffering from alopecia areata. This new insight into the often severe and psychologically burdensome disease serves as a beacon of hope for patients, as researchers begin to home in on a more precise etiology that may open the door for more targeted treatments. Past research has implicated follicular melanocytes to be the target structure in at least a proportion of patients suffering from alopecia areata. (Source: Modern Medicine)
Source: Modern Medicine - September 14, 2009 Category: Journals (General) Source Type: info

Serum levels of IL-18 and sIL-2R in patients with alopecia areata receiving combined therapy with oral cyclosporine and steroidsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, increased serum sIL-2R level and lower IL-18 level at baseline was associated with a poor prognosis in patients with AA. (Source: Experimental Dermatology)
Source: Experimental Dermatology - September 14, 2009 Category: Dermatology Authors: Deborah Lee, Soon-Kwon Hong, Sung-Wook Park, Dae-Young Hur, Ji-Hong Shon, Jae-Gook Shin, Seon-Wook Hwang, Ho-Suk Sung Source Type: journals

Five-year experience in the treatment of alopecia areata with DPCEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Diphencyprone is an effective and safe treatment of extensive AA. A long period of therapy is needed and will increase the percentage of responders especially in alopecia totalis and universalis. Maintenance therapy is recommended to reduce the risk of relapse. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - September 7, 2009 Category: Dermatology Authors: BM El-Zawahry, DA Bassiouny, A Khella, NS Zaki Source Type: journals

Etanercept: Alopecia areata: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - August 31, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Melanocytes: A possible autoimmune target in alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: Alopecia areata (AA) is thought to be an autoimmune disease directed against the hair follicle that results in hair loss. Observationally, AA tends to respond to immunosuppressive therapy and occurs in patients with other autoimmune phenomena, such as autoimmune thyroiditis and vitiligo. Further support comes from animal models. In a severe combined immunodeficiency (SCID) mouse model (used because these mice will not reject human lymphocytes or skin), investigators have shown that as T lymphocytes disappear from engrafted AA-affected skin, hair growth ensues. Moreover, if T cells from AA patients are stimul...
Source: Journal of the American Academy of Dermatology - August 26, 2009 Category: Dermatology Authors: Stephanie Trautman, Michele Thompson, Janet Roberts, Curtis T. Thompson Tags: Research Letters Source Type: journals

Instilled bimatoprost ophthalmic solution in patients with eyelash alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The objective of our 16-week, open-label, prospective study was to assess the safety and efficacy of instilled bimatoprost ophthalmic solution in promoting eyelash growth in patients with AA. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - August 26, 2009 Category: Dermatology Authors: Blanca E. Ochoa, Deborah Sah, Gloria Wang, Robert Stamper, Vera H. Price Tags: Research Letters Source Type: journals

Phase I/II randomized bilateral half-head comparison of topical bexarotene 1% gel for alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: Topical bexarotene 1% application is well tolerated and possibly effective. A randomized placebo-controlled trial should be conducted. (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - August 16, 2009 Category: Dermatology Authors: Rakhshandra Talpur, Jenny Vu, Roland Bassett, Victor Stevens, Madeleine Duvic Tags: Original Articles Source Type: journals

Diagnosing and treating hair loss.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Physicians should be careful not to underestimate the emotional impact of hair loss for some patients. Patients may present with focal patches of hair loss or more diffuse hair loss, which may include predominant hair thinning or increased hair shedding. Focal hair loss can be further broken down into scarring and nonscarring. Scarring alopecia is best evaluated by a dermatologist. The cause of focal hair loss may be diagnosed by the appearance of the patch and examination for fungal agents. A scalp biopsy may be necessary if the cause of hair loss is unclear. Alopecia areata presents with smooth hairless patches, whic...
Source: American Family Physician - August 14, 2009 Category: Primary Care Authors: Mounsey AL, Reed SW Tags: Am Fam Physician Source Type: journals

History of atopy or autoimmunity increases alopecia riskEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Individuals with a history of atopy or autoimmunity are at increased risk for developing alopecia areata, report investigators. (Source: MedWire News - Respiratory)
Source: MedWire News - Respiratory - August 3, 2009 Category: Respiratory Medicine Source Type: news

Female Adolescent Hair DisordersEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Hair abnormalities can have tremendous psychosocial impacts on adolescents and young adults, and may cause a great amount of anxiety regarding physical appearance, associated illnesses, and potential clinical course. The pathophysiology of such disorders may vary, with potential congenital, infectious, autoimmune, nutritional, or environmental causes. Hair abnormalities may present as changes in hair appearance or quality, becoming weathered or fractured. An abnormal increase in hair is present in hypertrichosis and hirsutism, whereas a thinning or shedding of hair is evident in patients with telogen effluvium an...
Source: Journal of Pediatric and Adolescent Gynecology - July 31, 2009 Category: OBGYN Authors: Elena Balestreire Hawryluk, Joseph C. English Tags: Pedi-Gyn Derm Source Type: journals

History of atopy or autoimmunity increases risk for alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Individuals with a history of atopy or autoimmunity have increased risk for developing alopecia areata, report investigators. (Source: MedWire News - Dermatology)
Source: MedWire News - Dermatology - July 24, 2009 Category: Dermatology Source Type: news

History of atopy or autoimmunity increases risk of alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: This analysis revealed that a history of atopy and autoimmune disease was associated with an increased risk of AA and that the results were consistent for both the severe subtype of AA (ie, alopecia totalis and alopecia universalis) and the localized subtype (ie, AA persistent). (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - July 16, 2009 Category: Dermatology Authors: Nazila Barahmani, Matthew B. Schabath, Madeleine Duvic, National alopecia areata Registry Tags: Original Articles Source Type: journals

Treatment of alopecia areata with fractional photothermolysis laserEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: International Journal of Dermatology)
Source: International Journal of Dermatology - July 13, 2009 Category: Dermatology Authors: Kwang Ho Yoo, Myeung Nam Kim, Beom Joon Kim, Chan Woong Kim Source Type: journals

A study of stress management in patients stricken by alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Alopecia Areata é uma dermatose caracterizada pela perda repentina de pêlos em uma única ou em várias áreas, na forma de círculo. Normalmente a perda se inicia no couro cabeludo, podendo também ocorrer em outras partes do corpo. Fatores emocionais traumáticos são referidos como desencadeantes. Um grupo de 12 pacientes acometidos de alopecia areata foi avaliado por meio de entrevista psicológica e do método de Rorschach (Sistema Compreensivo por Exner), com vista a identificar as condições de personalidade dos pacientes no que se refere ao manejo do estresse. Todos os pacientes relataram episódios traumáticos...
Source: Psicologia em Estudo - July 5, 2009 Category: Psychiatry & Psychology Source Type: journals

Immune-mediated skin lesions in patients treated with anti-tumour necrosis factor alpha inhibitors.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our results on patients treated with TNF antagonists strongly support a link between TNF inhibition and IMSL development. Although these clinical complications are rare, clinicians should be aware of their occurrence and should recognize them. PMID: 19579151 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Rheumatology)
Source: Scandinavian Journal of Rheumatology - July 3, 2009 Category: Rheumatology Authors: Exarchou S, Voulgari P, Markatseli T, Zioga A, Drosos A Tags: Scand J Rheumatol Source Type: journals

Treatment of alopecia areata in children.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19685659 [PubMed - in process] (Source: Pediatric Annals)
Source: Pediatric Annals - June 30, 2009 Category: Pediatrics Authors: Mukherjee N, Burkhart CN, Morrell DS Tags: Pediatr Ann Source Type: journals

Hair diagnoses and signs: the use of dermatoscopyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions. Dermatoscopy is most revealing in conditions resulting in gross changes in shaft outline and colour, where reflected light is valuable. It is unhelpful for detection of features within the shaft or at higher levels of resolution. When added to its ability to aid evaluation of scalp surface characteristics, dermatoscopy provides an excellent first-line method of assessment in clinics. In vivo it may aid screening and selection of hairs of greatest diagnostic yield for further assessment. In some instances, it may obviate the need for obtaining hair specimens and have implications for public health screening. Wh...
Source: Clinical And Experimental Dermatology - June 21, 2009 Category: Dermatology Authors: M. P. Wallace, D. A. de Berker Source Type: journals

Adalimumab: Alopecia areata: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - June 2, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Nails and hairEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: The hair and nail are appendages of the skin. They both hang off it and are part of it. Their growth, condition and integrity are indicators of both local and systemic pathologies. Age results in significant changes in hair growth with characteristic patterns of baldness evolving with time. Excess hair is largely a complaint of women where it may represent part of the normal spectrum of pigmented coarse hairs in a male distribution or be a sign of an endocrine pathology. The most common diseases causing disturbance of the nail are inflammatory diseases of the skin, such as psoriasis and eczema. These can also cau...
Source: Medicine - June 1, 2009 Category: Internal Medicine Authors: David de Berker Tags: Hair and nails Source Type: journals

The lived experience of alopecia areata: a qualitative study.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study explored experiences of individuals living with alopecia areata (AA) and alopecia universalis (AU) and investigated their accounts of adjusting to, and coping with, such conditions. Whilst previous research has primarily focused on the adverse psychosocial impact of alopecia, this investigation used Interpretive Phenomenological Analysis to provide a more holistic perspective. Biographical interviews were undertaken with 12 participants (7 women; 5 men) diagnosed with alopecia for periods ranging between 2 and 49 years. Results revealed that strategies used by participants evolved over time and that there were c...
Source: Body Image - May 31, 2009 Category: Psychiatry & Psychology Authors: Welsh N, Guy A Tags: Body Image Source Type: journals

Adalimumab: Alopecia areata: case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 4 (Source: Reactions Weekly)
Source: Reactions Weekly - May 30, 2009 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Prolactine levels in the patients with alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - May 6, 2009 Category: Dermatology Authors: M Gönül, Ü Gül, SK Çakmak, C Kılınç, S Kılınç Source Type: journals

[Update on the treatment of alopecia areata.]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Alopecia areata is nonscarring telogenic alopecia of autoimmune etiology. It is estimated to be the presenting complaint in 2 % of dermatologic consultations, and can appear at any age although it is more common in young patients. Treatment depends on several factors, such as extent of the disease and age, and may be local or systemic. Local treatments aim to achieve hair regrowth, but do not alter the underlying condition, whereas systemic treatments can modify the course of the disease. In neither case does treatment provide a cure. In this article, we review most of the therapeutic options described in the literatur...
Source: Actas Dermo-Sifiliograficas - April 30, 2009 Category: Dermatology Authors: Galán-Gutiérrez M, Rodríguez-Bujaldón A, Moreno-Giménez JC Tags: Actas Dermosifiliogr Source Type: journals

Fexofenadine hydrochloride enhances the efficacy of contact immunotherapy for extensive alopecia areata: Retrospective analysis of 121 casesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To study the effect of fexofenadine on extensive alopecia areata (AA), we evaluated retrospectively 121 patients with AA having alopecia in more than 50% of the scalp and followed them for at least 6 months. Patients were treated by immunotherapy using diphenylcyclopropenone or squaric acid dibutylester with or without oral fexofenadine. The regrowth score was estimated as decrease of Severity of Alopecia Tool (SALT) score. In AA with atopic background (atopic AA), the mean regrowth score of the fexofenadine group was 1.333 (n = 33) and that of the control 0.471 (n = 34). The fexofenadine group showed significantly better ...
Source: The Journal of Dermatology - April 28, 2009 Category: Dermatology Authors: Shigeki INUI, Takeshi NAKAJIMA, Naoyuki TODA, Satoshi ITAMI Tags: Original Articles Source Type: journals

Psoriasiform eruption associated with alopecia areata during infliximab therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - April 26, 2009 Category: Dermatology Authors: D. Nakagomi, K. Harada, A. Yagasaki, T. Kawamura, N. Shibagaki, S. Shimada Source Type: journals

Traumatic Events in the Past May Increase Vulnerability to Alopecia AreataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Adults with alopecia areata are significantly more likely to have a history of childhood and lifetime traumatic events than adults without this hair condition, which is thought to be an autoimmune disorder, according to results of a case-control study conducted in Belgium. Reuters Health Information (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - April 13, 2009 Category: Dermatology Tags: Dermatology Source Type: info

Alopecia areata is not associated with Helicobacter pyloriEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The results have shown that a relation between Helicobacter pylori and alopecia areata is not supported. We advise that H. pylori detection need not to be included in the laboratory work up of alopecia areata. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - April 7, 2009 Category: Dermatology Authors: Abdel Hafez Hisham Zayan, Mahran Ayman Mohamed, Hofny Eman M, Attallah Dalia Abdel Aziz, Sayed Doaa Sameer, Rashed Heba Source Type: journals

The efficacy of topical diphencyprone in the treatment of alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Maryam Akhyani, Hassan Seirafi, Farshad Farnaghi, Parastoo Banan, Vahide LajevardiIndian Journal of Dermatology 2009 54(1):88-89 (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - April 7, 2009 Category: Dermatology Authors: Maryam Akhyani, Hassan Seirafi, Farshad Farnaghi, Parastoo Banan, Vahide Lajevardi Source Type: journals

Non-infectious inflammatory disorders of the nail apparatusEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Inflammatory non-infectious diseases of the nails are not uncommon. The nail changes may look different in the same diseases, but also very much alike in various different nail disorders depending on which particular structure of the nail apparatus is involved. Of all skin diseases, psoriasis is the one with the most frequent nail involvement. The presence of many pits allows the diagnosis to be made, but salmon spots and onycholysis are also characteristic features. Lichen planus may occur isolated on the nails or in association with lesions of the skin and adjacent mucosal membranes. Longitudinal striations and loss of t...
Source: JDDG - April 6, 2009 Category: Dermatology Authors: Eckart Haneke Source Type: journals

Alexithymia in patients with alopecia areata: educational background much more important than traumatic eventsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion In adult AA patients, higher levels of education are significantly associated with lower alexithymia scores. Somewhat unexpectedly, we found no association between alexithymia score and emotional neglect or childhood traumatic experiences. Our results also confirm that alexithymia scores are significantly higher in adult patient with AA compared with control patients. None declared. (Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - April 2, 2009 Category: Dermatology Authors: R Willemsen, P Haentjens, D Roseeuw, J Vanderlinden Source Type: journals

Lack of efficacy of topical latanoprost and bimatoprost ophthalmic solutions in promoting eyelash growth in patients with alopecia areata.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19293023 [PubMed - in process] (Source: Journal of the American Academy of Dermatology)
Source: Journal of the American Academy of Dermatology - March 20, 2009 Category: Dermatology Authors: Roseborough I, Lee H, Chwalek J, Stamper RL, Price VH Tags: J Am Acad Dermatol Source Type: journals

Combination therapy with oral PUVA and corticosteroid for recalcitrant alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Alopecia areata (AA) is regarded as a tissue-specific autoimmune disease for which several therapies have been suggested to modify the immune reaction against HFs, such as contact immunotherapy, psoralen plus ultraviolet A (PUVA), corticosteroids, cyclosporine, minoxidil, and dithranol. However, severe type AA, such as alopecia totalis (AT) and alopecia universalis (AU), often show resistance against these therapies. We applied a combination therapy with oral corticosteroid and oral PUVA for intractable cases of AT and AU. These patients took 20 mg/day corticosteroid and were irradiated with UV...
Source: Archives of Dermatological Research - March 20, 2009 Category: Dermatology Tags: Archives of Dermatological Research Source Type: journals

Adalimumab: Alopecia areata: case reportEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Reactions)
Source: Reactions - March 17, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Adalimumab: Alopecia areata: case report.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Page: 5 (Source: Reactions Weekly)
Source: Reactions Weekly - March 15, 2009 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Capsaicin vs. clobetasol for the treatment of localized alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Journal of the European Academy of Dermatology and Venereology)
Source: Journal of the European Academy of Dermatology and Venereology - March 5, 2009 Category: Dermatology Authors: AH Ehsani, S Toosi, H Seirafi, M Akhyani, M Hosseini, R Azadi, P Noormohamadpour, A Ghanadan Source Type: journals

Is Helicobacter pylori infection associated with alopecia areata?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Based on these results, the relation between H. pylori and AA is not supported. We advise that H. pylori detection should not be included in the laboratory workup of AA. (Source: Journal of Cosmetic Dermatology)
Source: Journal of Cosmetic Dermatology - February 17, 2009 Category: Dermatology Authors: Hisham Zayan Abdel-Hafez, Ayman Mohamed Mahran, Eman RM Hofny, Dalia Abdel Aziz Attallah, Doaa Sameer Sayed, Hebat-Allah G Rashed Source Type: journals

Scalp dermoscopy of androgenetic alopecia in Asian people.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, dermoscopy is useful to diagnose AGA and FAGA and provides insights into the pathogenesis of AGA. PMID: 19284450 [PubMed - in process] (Source: The Journal of Dermatology)
Source: The Journal of Dermatology - February 1, 2009 Category: Dermatology Authors: Inui S, Nakajima T, Itami S Tags: J Dermatol Source Type: journals

Trace element levels in alopecia areataEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: We conclude that copper and magnesium levels are not altered in AA, but the decreased zinc levels found in our study may merit further investigation of the relationship. (Source: Indian Journal of Dermatology, Venereology and Leprology)
Source: Indian Journal of Dermatology, Venereology and Leprology - January 25, 2009 Category: Dermatology Authors: Bhat Yasmeen J, Manzoor Sheikh, Khan A R, Qayoom Seema Source Type: journals