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The complete three-vessel view in prenatal detection of congenital heart defectsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To evaluate the effectiveness of the complete three-vessel view (c3VV) in assessment of fetuses with prenatally diagnosed congenital heart defects (CHD).Fetuses with prenatal suspicion of CHD were prospectively recruited into the study. All examinations included a c3VV for assessment of abnormalities in alignment, arrangement, vessel size, number of vessels, aortic arch sidedness and color flow mapping. Definite diagnoses of CHD were based on neonatal cardiologic exams or postnatal autopsy.Of 106 consecutive fetuses with CHD, 75 were shown to have at least one abnormality on the c3VV, a detection rate of 70.8%. When septal...
Source: Prenatal Diagnosis - November 12, 2009 Category: Perinatology & Neonatology Authors: Theera Tongsong, Fuanglada Tongprasert, Kasemsri Srisupundit, Suchaya Luewan Source Type: journals

Posterior Root Enlargement for Aortic Valve Replacement Associated with Unexpected Anomalous Right Coronary ArteryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We present the case of a 21-year-old man with congenital aortic stenosis and small aortic root, who had an intraoperative diagnosis of ARCA. After posterior root enlargement through the noncoronary sinus, ARCA was mobilized from the aortic root and reimplanted into the right coronary sinus. Postoperative follow-up of the patient was uneventful. (J Card Surg ****;**:**-**) (Source: Journal of Cardiac Surgery)
Source: Journal of Cardiac Surgery - November 11, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Kaan Inan, Alper Ucak, Burak Onan, Burak Tamtekin, Veysel Temizkan, Ahmet Turan Yilmaz Source Type: journals

Transcatheter aortic valve implantationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Opinion statement Aortic stenosis is the most important valvular heart disease affecting the elderly population. Surgical aortic valve replacement is the mainstay of treatment, although a substantial number of patients are considered high risk for surgery. Many of these patients do not undergo surgery and have poor outcomes from medically treated symptomatic, severe aortic stenosis. Transcatheter aortic valve implantation (TAVI) provides a promising treatment option for some of these patients. Several devices are under investigation. The Edwards Sapien valve (Edwards Lifesciences, Irvine, CA) and the CoreVal...
Source: Current Treatment Options in Cardiovascular Medicine - November 5, 2009 Category: Cardiology Tags: Current Treatment Options in Cardiovascular Medicine Source Type: journals

Echocardiography in hypertrophic cardiomyopathy diagnosis, prognosis, and role in managementEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hypertrophic cardiomyopathy (HCM) is diagnosed on the basis of left ventricular (LV) hypertrophy for which there is insufficient explanation (e.g. mild hypertension or mild aortic stenosis with marked hypertrophy). Echocardiography is an invaluable tool in the diagnosis and follow-up of patients with HCM. Echocardiographic assessment requires a comprehensive assessment in several imaging planes with careful attention to correct beam alignment in order to minimize errors in the measurement of LV wall thickness and appropriate identification of hypertrophy with an unusual distribution. (Source: European Journal of Echocardiography)
Source: European Journal of Echocardiography - November 4, 2009 Category: Cardiology Authors: Williams, L.K., Frenneaux, M.P., Steeds, R.P. Tags: BRITISH SOCIETY OF ECHOCARDIOGRAPHY AUTUMN SUPPLEMENT 2009 Source Type: journals

The left axillary artery -- a new approach for transcatheter aortic valve implantation [Original articles]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: TAVI can be performed through a left axillary artery approach. This is a technically simple procedure and, in this small initial clinical experience, was performed with encouraging results. It is a realistic option in patients in whom neither the trans-femoral or trans-apical approaches are optimal. (Source: European Journal of Cardio-Thoracic Surgery)
Source: European Journal of Cardio-Thoracic Surgery - October 27, 2009 Category: Cardiovascular & Thoracic Surgery Authors: De Robertis, F., Asgar, A., Davies, S., Delahunty, N., Kelleher, A., Trimlett, R., Mullen, M., Moat, N. Tags: Minimally invasive surgery, Valve disease Original articles Source Type: journals

Percutaneous Implantation of CoreValve Aortic Prostheses in Patients With a Mechanical Mitral Valve.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report our experience with percutaneous aortic valve implantation in 4 patients with severe aortic stenosis, previously operated on for mitral valve replacement with a mechanical prosthesis. All patients underwent uneventful percutaneous retrograde CoreValve implantation (CoreValve Inc, Irvine, CA). No deformation of the nitinol tubing of the prostheses (ie, neither distortion nor malfunction of the mechanical valve in the mitral position) occurred in any of the patients. All patients are alive and asymptomatic at a mean follow-up of 171 days. PMID: 19853076 [PubMed - in process] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 27, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Bruschi G, De Marco F, Oreglia J, Colombo P, Fratto P, Lullo F, Paino R, Frigerio M, Martinelli L, Klugmann S Tags: Ann Thorac Surg Source Type: journals

Transcatheter aortic valve implantation in patients with very high risk for conventional aortic valve replacement.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Transcatheter aortic valve implantation in patients with severe aortic stenosis and a very high risk for aortic valve replacement is feasible and may be a reasonable treatment option in these patients. PMID: 19853095 [PubMed - in process] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 27, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Thielmann M, Wendt D, Eggebrecht H, Kahlert P, Massoudy P, Kamler M, Erbel R, Jakob H, Sack S Tags: Ann Thorac Surg Source Type: journals

Mechanical strain and the aortic valve: influence on fibroblasts, extracellular matrix, and potential stenosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: A specific pattern of extracellular matrix protein expression was found in relation to mechanical strain on human aortic valve cusp tissue and in mechanically stimulated human valvular fibroblasts. This new insight into the process of aortic valve degeneration may be important for further therapeutic approaches to ameliorate the progression or even the initiation of potential aortic valve stenosis. PMID: 19853097 [PubMed - in process] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 27, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Lehmann S, Walther T, Kempfert J, Rastan A, Garbade J, Dhein S, Mohr FW Tags: Ann Thorac Surg Source Type: journals

Percutaneous aortic valve replacement for the treatment of aortic stenosis: early experience in BrazilEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The use of the CoreValve endoprosthesis for the treatment of aortic stenosis proved to be feasible and showed encouraging results in this early experience made in our midst.FUNDAMENTO: La sustitución percutánea de la válvula aórtica en el tratamiento de la estenosis aórtica es una alternativa disponible y eficaz para pacientes de alto riesgo quirúrgico, especialmente los de edad avanzada y comorbilidades. OBJETIVO: Los autores relatan la experiencia inicial del empleo de la endoprótesis CoreValve en nuestro medio. MÉTODOS: En enero de 2008 se sometió a dos pacientes a la sustitución percutánea de la ...
Source: Arquivos Brasileiros de Cardiologia - October 23, 2009 Category: Cardiology Source Type: journals

Mechanisms of Aortic Valve Calcification: The LDL-Density-Radius Theory A Translation from Cell Signaling to Physiology.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Recent epidemiological studies have revealed the risk factors associated for vascular atherosclerosis, including male gender, smoking, hypertension and elevated serum cholesterol, are similar to the risk factors associated with development of aortic valve stenosis. An increasing number of models of experimental hypercholesterolemia demonstrates features of atherosclerosis in the aortic valve(AV), which are similar to the early stages of vascular atherosclerotic lesions. The experimental and clinical studies demonstrate that the hypercholesterolemic AV develops an atherosclerotic lesion which is proliferative, and expre...
Source: American Journal of Physiology. Heart and Circulatory Physiology - October 23, 2009 Category: Physiology Authors: Rajamannan NM Tags: Am J Physiol Heart Circ Physiol Source Type: journals

Percutaneous Implantation of CoreValve Aortic Prostheses in Patients With a Mechanical Mitral Valve [CASE REPORTS]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report our experience with percutaneous aortic valve implantation in 4 patients with severe aortic stenosis, previously operated on for mitral valve replacement with a mechanical prosthesis. All patients underwent uneventful percutaneous retrograde CoreValve implantation (CoreValve Inc, Irvine, CA). No deformation of the nitinol tubing of the prostheses (ie, neither distortion nor malfunction of the mechanical valve in the mitral position) occurred in any of the patients. All patients are alive and asymptomatic at a mean follow-up of 171 days. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 22, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Bruschi, G., De Marco, F., Oreglia, J., Colombo, P., Fratto, P., Lullo, F., Paino, R., Frigerio, M., Martinelli, L., Klugmann, S. Tags: Valve disease CASE REPORTS Source Type: journals

Transcatheter Aortic Valve Implantation in Patients With Very High Risk for Conventional Aortic Valve Replacement [ORIGINAL ARTICLES: ADULT CARDIAC]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Transcatheter aortic valve implantation in patients with severe aortic stenosis and a very high risk for aortic valve replacement is feasible and may be a reasonable treatment option in these patients. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 22, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Thielmann, M., Wendt, D., Eggebrecht, H., Kahlert, P., Massoudy, P., Kamler, M., Erbel, R., Jakob, H., Sack, S. Tags: Valve disease ORIGINAL ARTICLES: ADULT CARDIAC Source Type: journals

Mechanical Strain and the Aortic Valve: Influence on Fibroblasts, Extracellular Matrix, and Potential Stenosis [ORIGINAL ARTICLES: ADULT CARDIAC]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions A specific pattern of extracellular matrix protein expression was found in relation to mechanical strain on human aortic valve cusp tissue and in mechanically stimulated human valvular fibroblasts. This new insight into the process of aortic valve degeneration may be important for further therapeutic approaches to ameliorate the progression or even the initiation of potential aortic valve stenosis. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - October 22, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Lehmann, S., Walther, T., Kempfert, J., Rastan, A., Garbade, J., Dhein, S., Mohr, F. W. Tags: Molecular biology, Valve disease ORIGINAL ARTICLES: ADULT CARDIAC Source Type: journals

Association Between Carotid and Coronary Artery Disease in Patients With Aortic Valve Stenosis: An Angiographic StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion: In patients with symptomatic aortic stenosis, the presence of significant carotid artery disease is a strong marker of significant coronary artery disease. (Source: Angiology)
Source: Angiology - October 22, 2009 Category: Cardiology Authors: Antonini-Canterin, F., Leiballi, E., Capanna, M., Burelli, C., Cassin, M., Macor, F., Grandis, U., Nicolosi, G. L. Tags: Articles Source Type: journals

The Hemodynamic Performance of Percutaneous vs. Surgical Bioprosthesis for Severe Aortic StenosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: AccessMedicine Updates)
Source: AccessMedicine Updates - October 22, 2009 Category: Internal Medicine Source Type: info

Identification and characterization of seven novel mutations of elastin gene in a cohort of patients affected by supravalvular aortic stenosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Zelante & Giuseppe Merla (Source: European Journal of Human Genetics)
Source: European Journal of Human Genetics - October 20, 2009 Category: Genetics & Stem Cells Authors: Lucia MicaleMaria Giuseppina TurturoCarmela FuscoBartolomeo AugelloLuis A Pérez JuradoClaudia IzziMaria Cristina DigilioDonatella MilaniElisabetta LapiLeopoldo ZelanteGiuseppe Merla Source Type: journals

Postnatal Angiographic Appearance of Left Ventricular Myocardium in Fetal Patients With Aortic Stenosis Having In-Utero Aortic ValvuloplastyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, patients after FAV have angiographically abnormal left ventricles, commonly involving extensive trabeculations of the free wall, but without septal involvement. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - October 20, 2009 Category: Cardiology Authors: Babar Sultan Hasan, John Finbarr Keane, Wayne Tworetzky, James E. Lock, Audrey Chung Marshall Tags: Congenital Heart Disease Source Type: journals

Images in cardiovascular medicine: transapical aortic valve implantation in a patient with severe aortic stenosis and Pott disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PMID: 19841305 [PubMed - in process] (Source: Circulation)
Source: Circulation - October 19, 2009 Category: Cardiology Authors: Bagur RH, Doyle D, Dumont E, De Larochellière R, Lemieux J, Bergeron S, Gingras JL, Bertrand OF, Pibarot P, Rodés-Cabau J Tags: Circulation Source Type: journals

Aortic stenosis and statinsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To the Editor: The meta-analysis by Takagi and coworkers addresses the effect of statins on aortic stenosis. The authors conclude that statins do retard the progression of aortic stenosis by retarding the increase in peak aortic jet velocity (PAJV) but not reducing the decrease in aortic valve area (AVA). The recent publication of the Simvastatin and Ezetimibe in Aortic Stenosis (SEAS) study prompted us to do a meta-analysis on the same question to see whether there is any difference in the summary estimate. During this process, we realized that there were some errors in the calculation of the summary estimate. In brief, ...
Source: The Journal of Thoracic and Cardiovascular Surgery - October 19, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Deepak Vedamurthy, Janos Molnar, Rohit Arora Tags: Letters to the Editor Source Type: journals

Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome [Patient-Oriented and Epidemiological Research]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We evaluated the role of sterol-regulatory element binding protein (SREBP)-1c/peroxisome proliferator activated receptor- (PPAR) pathway on heart lipotoxicity in patients with metabolic syndrome (MS) and aortic stenosis (AS). Echocardiographic parameters of heart function and structural alterations of LV specimens were studied in patients with (n = 56) and without (n = 61) MS undergoing aortic valve replacement. Tissues were stained with hematoxylin-eosin (H and E) and oil red O for evidence of intramyocyte lipid accumulation. The specimens were also analyzed with PCR, Western blot, and immunohistochemical analysis for SRE...
Source: The Journal of Lipid Research - October 15, 2009 Category: Lipidology Authors: Marfella, R., Di Filippo, C., Portoghese, M., Barbieri, M., Ferraraccio, F., Siniscalchi, M., Cacciapuoti, F., Rossi, F., D'Amico, M., Paolisso, G. Tags: Patient-Oriented and Epidemiological Research Source Type: journals

When operable patients become inoperable: conversion of a surgical aortic valve replacement into transcatheter aortic valve implantation [Proposal for bail-out procedures - Valves]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Transcatheter aortic valve implantation (TAVI) is a relatively new treatment option for inoperable patients with severe aortic stenosis (AS). This case describes how a planned conventional surgical aortic valve replacement (AVR) on a 73-year-old woman was successfully converted to a TAVI procedure. On extracorporal circulation it was reconized that the aortic annulus, the coronary ostiae and the proximal part of the ascending aorta were severely calcified making valve implantation impossible. Surgical closure without valve substitution was estimated to be associated with a high risk of mortality due to the imparied left ve...
Source: Interactive CardioVascular and Thoracic Surgery - October 14, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Olsen, L. K., Arendrup, H., Engstrom, T., Sondergaard, L. Tags: Valve disease Proposal for bail-out procedures - Valves Source Type: journals

Dynamic left ventricular dyssynchrony: a potential cause of no contractile reserve in patients with low-gradient aortic stenosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report the case of a patient who presented AS associated with left ventricular (LV) dyssynchrony. A DSE was performed, which showed no contractile reserve but an increase in LV dyssynchrony. In this patient, the reduced aortic valve area was probably because of the association of inadequate forward stroke volume due to ischaemic cardiomyopathy and fixed severe AS. The cause of LV dysfunction may include a certain degree of intrinsic myocardial dysfunction due to ischaemic cardiomyopathy and afterload mismatch associated with dynamic LV dyssynchrony, which could be a determinant of forward stroke volume response. (Source...
Source: European Journal of Echocardiography - October 12, 2009 Category: Cardiology Authors: Lancellotti, P., Szymanski, C., Moonen, M., Garweg, C., O'Connor, K., Tribouilloy, C., Pierard, L. A. Tags: CASE REPORTS Source Type: journals

Mechanical Aortic Valve Replacement in Children and Adolescents After Previous Repair of Congenital Heart DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Due to improved outcome after surgery for congenital heart defects, children, adolescents, and grown-ups with congenital heart defects become an increasing population. In order to evaluate operative risk and early outcome after mechanical aortic valve replacement (AVR) in this population, we reviewed patients who underwent previous repair of congenital heart defects. Between July 2002 and November 2008, 15 (10 male and 5 female) consecutive patients (mean age 14.5 ± 10.5 years) underwent mechanical AVR. Hemodynamic indications for AVR were aortic stenosis in four (27%), aortic insufficiency in eight (53%), and mixed disea...
Source: Artificial Organs - October 9, 2009 Category: Transplant Surgery Authors: Aron-Frederik Popov, Kasim Oguz Coskun, Theodor Tirilomis, Jan Dieter Schmitto, José Hinz, Thomas Kriebel, Friedrich Albert Schoendube, Wolfgang Ruschewski Source Type: journals

One patient’s story: in utero heart surgery saves a babyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The first thing you notice about Ann Louise Atherton (her real name is Hazel, but everyone calls her Ann Louise) is her eyes: playful, brilliant blue and sparkling with humor. When she throws a toy and you pick it up, she beams, knowing she’s hooked you into playing fetch. Sitting in her Princess stroller and playing with her mother’s iPhone, a small catheter tube by her hip is the only sign of the risky, life-saving heart surgery that Ann Louise went through before she was even born. Early in her pregnancy, Mary Beth Atherton and her husband, Andrew, learned that Ann Louise’s still-developing heart was showing signs...
Source: Thrive, Children's Hospital Boston - October 7, 2009 Category: Pediatrics Authors: Steve Coldwell Tags: All posts One parent's story congential heart defect critical aortic stenosis heart repair in utero surgery Source Type: organizations

Combined Aortic Root and Right Ventricular Outflow Tract Replacement with Mechanical Conduits in Adult Patients after Repeated Surgery for Congenital Heart Disease*Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Thorac cardiovasc Surg 2009; 57: 395-398DOI: 10.1055/s-0029-1185869Abstract To manage aortic root aneurysms and right ventricular outflow tract (RVOT) graft dysfunction in adult patients after repeated surgery for congenital heart disease, we performed combined prosthetic aortic root and RVOT replacement. The procedure was performed in 5 patients (2 truncus arteriosus, 2 variants of tetralogy of Fallot, and 1 congenital aortic stenosis), aged 23, 24, 27, 29, and 34 years, who presented with progressive dilation of the aortic root and aortic regurgitation as well as RVOT graft dysfunction. All patients had undergone a media...
Source: The Thoracic and Cardiovascular Surgeon - October 1, 2009 Category: Cardiovascular & Thoracic Surgery Tags: Original Cardiovascular Source Type: journals

Aortic valve replacement in a patient with a retrosternal gastric tube and porcelain aorta.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 66-year-old man with severe aortic stenosis had previously undergone esophagectomy with retrosternal gastric tube (GT) reconstruction for esophageal cancer. A chest computed tomography scan demonstrated severe aortic calcification, and we treated him with median sternotomy. A small upper laparotomy was made, and the surface of the GT was detected. The posterior and right sides of the GT were dissected, and the pericardium was then opened. An aortic cross clamp was performed in the least calcified lesion of the ascending aorta, and an aortotomy was performed just above the sinotubular junction. The aortic valve was su...
Source: Annals of Thoracic and Cardiovascular Surgery - October 1, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Fukui S, Mitsuno M, Yamamura M, Tanaka H, Ryomoto M, Nishi H, Tsujiya N, Kajiyama T, Miyamoto Y Tags: Ann Thorac Cardiovasc Surg Source Type: journals

Pulmonary artery aneurysm associated with severe degenerative aortic stenosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a pulmonary artery (PA) aneurysm associated with severe aortic stenosis and an aortic root dilatation occurring in a 59-year-old woman who presented with dyspnoea and chest pain. PA aneurysms are rare, and there are no definitive guidelines on its management. There are contentious opinions on whether such aneurysms should be managed conservatively or surgically. Our patient had associated aortic stenosis and underwent a successful aortic valve replacement and PA aneurysm repair. This case illustrates that concomitant PA repair with other cardiothoracic surgery can be performed safely, even in patients with modera...
Source: Singapore Medical Journal - October 1, 2009 Category: Journals (General) Authors: Ling PK Tags: Singapore Med J Source Type: journals

Combined aortic root and right ventricular outflow tract replacement with mechanical conduits in adult patients after repeated surgery for congenital heart disease.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Combined aortic root and RVOT replacement with mechanical conduits in adult patients after repeated surgery for congenital heart disease is a complex operation requiring long CPB time. However, this procedure has the potential to avoid a predictable reoperation associated with conventional biological graft replacement. PMID: 19795325 [PubMed - in process] (Source: The Thoracic and Cardiovascular Surgeon)
Source: The Thoracic and Cardiovascular Surgeon - September 30, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Ono M, Goerler H, Boethig D, Westhoff-Bleck M, Breymann T Tags: Thorac Cardiovasc Surg Source Type: journals

Surgical outcomes and post-operative changes in patients with significant aortic stenosis and severe left ventricle dysfunction.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Little is known regarding long-term survival and changes in systolic function following surgery after the occurrence of a severe left ventricular (LV) dysfunction in patients with severe aortic stenosis. Inclusion criteria were an aortic valve area less than 1 cm(2) and an LV ejection fraction (EF) less than 35%. Between January 1990 and July 2007, 41 (male: 30) patients were identified. The pre-operative mean EF and mean aortic valve area were 26.7+/-6.1% and 0.54+/-0.2 cm(2), respectively. Concomitant coronary artery bypass surgery was performed in 8 patients (19.6%). Immediate post-operative echocardiogram showed to...
Source: J Korean Med Sci - September 30, 2009 Category: Journals (General) Authors: Jung SH, Lee JW, Je HG, Choo SJ, Chung CH, Song H Tags: J Korean Med Sci Source Type: journals

Spontaneous Cerebral Embolism in a Forty Year Old Man: Case Report and Review of the LiteratureEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Calcific cerebral emboli are a known complication of aortic stenosis. Most of these emboli are related to traumatic disruption, via cardiac catheterization, valvotomy, or valve replacement. Spontaneous calcific cerebral emboli are extremely rare and are typically associated with heavily calcified bicuspid aortic valves, especially when they occur in young adults. The authors report a case of a spontaneous calcific embolic infarction in a 40-year-old man with a trileaflet aortic valve. (Source: Journal of the American Society of Echocardiography)
Source: Journal of the American Society of Echocardiography - September 30, 2009 Category: Cardiology Authors: Idan Roifman, Rafael S. Glikstein, Lawrence Rudski Tags: Case Reports Source Type: journals

Gender-based differences in the association of atherosclerosis and severe calcific aortic stenosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Gender-specific differences in left ventricular geometry in patients with aortic stenosis (AS) have been investigated in the past; however, gender-specific role of vascular inflammation in the pathogenesis of AS remains unknown. (Source: Cardiovascular Revascularization Medicine)
Source: Cardiovascular Revascularization Medicine - September 30, 2009 Category: Cardiology Authors: Sachin S. Goel, Akin Cam, E. Murat Tuzcu, Samir R. Kapadia Tags: Special Feature Source Type: journals

Cardiac chest pain in children.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: Most children with CP were older than 12 years old. CDs were frequent and about half of them were thought to directly cause pain. So, further investigations according to standard algorithms are needed in the evaluation of children with CP. Other important result is the increased risk of CD found in elder children. PMID: 19819792 [PubMed - in process] (Source: Anadolu Kardiyol Der...)
Source: Anadolu Kardiyol Der... - September 30, 2009 Category: Cardiology Authors: Cağdaş DN, Paç FA Tags: Anadolu Kardiyol Derg Source Type: journals

Transcatheter Aortic Valve Trial UnderwayEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Aortic valve replacement is a standard and life-saving surgery for patients with aortic stenosis, a common morbidity in the elderly. A trial now in progress is assessing whether a percutaneous method for replacing a calcified aortic valve is as effective as the surgical standard of care. (Source: Cardiology News)
Source: Cardiology News - September 30, 2009 Category: Cardiology Authors: MITCHEL L. ZOLER Tags: News Source Type: news

Med Sci Monit 2009; 15(10):CR534-538 "Prolonged QT dispersion in children with congenital valvular aortic stenosis"Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Risk of ventricular arrhythmia increases with the degree of aortic valve stenosis and cardiac muscle hypertrophy. QT dispersion is prolonged in children with aortic valve stenosis, particularly in patients with arrhythmia, and increases with pressure gradient and left ventricular mass index. (Source: Medical Science Monitor)
Source: Medical Science Monitor - September 30, 2009 Category: Research Tags: Original article Source Type: journals

Comparison of Cardiac Computed Tomographic Angiography to Transesophageal Echocardiography for Evaluation of Patients With Native Valvular Heart DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In conclusion, CCTA exhibited high diagnostic performance for detection of aortic and mitral stenoses and limited diagnostic performance for aortic regurgitation, mitral regurgitation, and mitral valve prolapse; tricuspid regurgitation could not be evaluated. The ability of CCTA to provide comprehensive assessment of valvular function is variable. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - September 28, 2009 Category: Cardiology Authors: Troy M. LaBounty, Sidney Glasofer, Richard B. Devereux, Fay Y. Lin, Jonathan W. Weinsaft, James K. Min Tags: Valvular Heart Disease Source Type: journals

Predictors of Technical Success and Postnatal Biventricular Outcome After In Utero Aortic Valvuloplasty for Aortic Stenosis With Evolving Hypoplastic Left Heart Syndrome.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions-Technically successful aortic valvuloplasty alters left heart valvar growth in fetuses with aortic stenosis and evolving hypoplastic left heart syndrome and, in a subset of cases, appeared to contribute to a biventricular outcome after birth. Fetal aortic valvuloplasty carries a risk of fetal demise. Fetuses undergoing in utero aortic valvuloplasty with an unfavorable multivariable threshold score at the time of intervention are very unlikely to achieve a biventricular circulation postnatally. PMID: 19786635 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - September 27, 2009 Category: Cardiology Authors: McElhinney DB, Marshall AC, Wilkins-Haug LE, Brown DW, Benson CB, Silva V, Marx GR, Mizrahi-Arnaud A, Lock JE, Tworetzky W Tags: Circulation Source Type: journals

CVN: Heart MinuteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Heart Minute: Left Ventricle in Aortic Stenosis (Source: Cardiosource)
Source: Cardiosource - September 25, 2009 Category: Cardiology Source Type: organizations

Obstruction and sequestration: a case of apical hypertrophic cardiomyopathy concomitant with subaortic obstruction, apical sequestration, and valvular aortic stenosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We presented an unique case of apical hypertrophic cardiomyopathy concomitant with subaortic obstruction, apical sequestration, and valvular aortic stenosis. The echocardiographic findings were conflicting and characterized by quadruple pressure gradients within the left ventricle, which were compatible with the findings of 64-slice computed tomography imaging and cardiac catheterization. Content Type Journal ArticleCategory Case in PointDOI 10.1007/s10554-009-9494-6Authors Chao-Chin Chen, Lo-Tung Poh-Ai Hospital Division of Cardiology, Department of Medicine 83 Nan Chang St. Lotung I-Lan 265 TaiwanMeng-Huan Lei, Lo...
Source: The International Journal of Cardiovascular Imaging - September 24, 2009 Category: Radiology Tags: The International Journal of Cardiovascular Imaging (formerly Cardiac Imaging) Source Type: journals

Management of mild aortic stenosis at the time of coronary artery bypass surgery: should the valve be replaced?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: Prophylactic AVR for mild AS at CABG does not confer a survival benefit, and the likelihood of requiring AVR after CABG alone is low in the first 5 years. The decision to intervene on the valve is critically dependent upon the incremental operative risk imposed by concomitant AVR and late survival. PMID: 19766811 [PubMed - in process] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - September 24, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Sareyyupoglu B, Sundt TM, Schaff HV, Enriquez-Sarano M, Greason KL, Suri RM, Burkhart HM, Park SJ, Dearani JA, Daly RC, Orszulak TA Tags: Ann Thorac Surg Source Type: journals

FORUM EKSPERTÓW POL-TAVI FIRST – Polish report on transcatheter aortic valve implantation (TAVI) of Edwards-Sapien prosthesis in the first 19 high risk patients with severe aortic stenosis and comorbiditiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patients with severe symptomatic aortic stenosis, who from November 2008 to March 2009 were treated with Edwards-Sapien transcatheter aortic valve implantation (TAVI) within the POL-TAVI First Polish Registry, were included in the analysis. Nineteen patients aged 78±4,8 years with high operation risk and Logistic EuroSCORE 25 ± 7.6% were reported (74% were females). In 15 (79%) patients the valve was implanted transapically (TA), in the other four (21%) – via the femoral arterial access (TF). The valve was successfully implanted in 16 (84%) patients, in one patient aortic valvuloplasty alone was perform...
Source: Articles of Polish Journal of Cardio-Thoracic Surgery - TERMEDIA publishing house - September 23, 2009 Category: Cardiovascular & Thoracic Surgery Source Type: journals

Meta-Analysis of Prognostic Value of Stress Testing in Patients With Asymptomatic Severe Aortic StenosisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The management strategy in asymptomatic patients with severe aortic stenosis (AS) is controversial. Aortic valve replacement has significant morbidity and mortality, while there is a risk for sudden cardiac death with conservative management. There is no consensus on the prognostic value of stress testing to stratify management. A pooled analysis of studies in patients with severe AS was performed to assess the prognostic value of stress testing for adverse events, including angina, dyspnea, acute heart failure, sudden death, and symptoms requiring aortic valve replacement. A search of published research was performed usin...
Source: The American Journal of Cardiology - September 22, 2009 Category: Cardiology Authors: Asim M. Rafique, Simon Biner, Indraneil Ray, James S. Forrester, Kirsten Tolstrup, Robert J. Siegel Tags: Valvular Heart Disease Source Type: journals

TCT: Transcatheter valve therapy explodes, standardization soughtEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
SAN FRANSISCO—An estimated 10,000 transcatheter heart valves have been implanted in patients with critical valvular aortic stenosis, and the researchers, who have their eyes on U.S. approval, are now seeking to standardize the techniques and trial expectations, according to a presentation by Martin B. Leon, MD, at the 21st annual Transcatheter Cardiovascular Therapeutics (TCT) symposium. (Source: Cardiovascular Business News)
Source: Cardiovascular Business News - September 22, 2009 Category: Cardiology Tags: Latest News Source Type: news

Management of Mild Aortic Stenosis at the Time of Coronary Artery Bypass Surgery: Should the Valve Be Replaced? [ORIGINAL ARTICLES: ADULT CARDIAC]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions Prophylactic AVR for mild AS at CABG does not confer a survival benefit, and the likelihood of requiring AVR after CABG alone is low in the first 5 years. The decision to intervene on the valve is critically dependent upon the incremental operative risk imposed by concomitant AVR and late survival. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - September 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Sareyyupoglu, B., Sundt, T. M., Schaff, H. V., Enriquez-Sarano, M., Greason, K. L., Suri, R. M., Burkhart, H. M., Park, S. J., Dearani, J. A., Daly, R. C., Orszulak, T. A. Tags: Coronary disease, Valve disease ORIGINAL ARTICLES: ADULT CARDIAC Source Type: journals

Is the aortic valve pathology type different for early and late mortality in concomitant aortic valve replacement and coronary artery bypass surgery? [Institutional report - Valves]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We assessed the effects of aortic valve pathology type on the long-term outcomes of patients who underwent concomitant aortic valve replacement (AVR) and coronary artery bypass grafting (CABG) surgery. We retrospectively reviewed 150 patients who underwent AVR-CABG at our institution between January 1997 and December 2006. We divided patients into aortic stenosis (AS), aortic regurgitation (AR), and mixed-type groups consisting of 98 (65.3%), 20 (13.3%) and 32 (21.3%) patients, respectively. The AS group had more female patients, a higher mean angina class, older mean patient age, increased history of previous myocardial i...
Source: Interactive CardioVascular and Thoracic Surgery - September 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Gunay, R., Sensoz, Y., Kayacioglu, I., Tuygun, A. K., Balci, A. Y., Kisa, U., Murat Demirtas, M., Yekeler, I. Tags: Institutional report - Valves Source Type: journals

Apico-aortic valved conduit as an alternative for aortic valve re-replacement in severe prosthesis-patient mismatch [Proposal for bail-out procedures - Valves]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Off-pump implantation of an apico-aortic bioprothesis-valved conduit in a 75-year-old female symptomatic patient with severe prosthesis–patient mismatch secondary to a previous aortic valve replacement, calcified ascending aorta, tight adhesion with the sternum, was successfully conducted to relieve the left ventricle from severe aortic stenosis. (Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - September 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Chahine, J. H., El-Rassi, I., Jebara, V. Tags: Proposal for bail-out procedures - Valves Source Type: journals

Apico-aortic conduit for aortic stenosis with a porcelain aorta; technical modification for apical outflow [Case report - Cardiac general]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A successful apico-aortic bypass for a patient with a porcelain aorta suffering from aortic stenosis is reported. A sewing cuff with an outflow graft to the apex and a hand-made composite graft were used instead of a rigid apical connector. (Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - September 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Hirota, M., Oi, M., Omoto, T., Tedoriya, T. Tags: Case report - Cardiac general Source Type: journals

Transcatheter Aortic Valve Implantation: Review of the Nature, Management, and Avoidance of Procedural ComplicationsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Transcatheter aortic valve implantation (TAVI) is becoming a reality in the management of patients with severe aortic stenosis and high or prohibitive risk for standard surgical management. Current understanding of the potential adverse events associated with this procedure is limited. Risks associated with TAVI differ from those related to surgical valve replacement and include vascular injury; stroke; cardiac injury such as heart block, coronary obstruction, and cardiac perforation; paravalvular leak; and valve misplacement. The clinical experience of multiple centers experience with different valve implantation systems ...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - September 20, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Masson, J.-B., Kovac, J., Schuler, G., Ye, J., Cheung, A., Kapadia, S., Tuzcu, M. E., Kodali, S., Leon, M. B., Webb, J. G. Tags: State-of-the-Art Paper Source Type: journals

Expanding the Eligibility for Transcatheter Aortic Valve Implantation: The Trans-Subclavian Retrograde Approach Using the III Generation CoreValve Revalving SystemEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions TAVI by subclavian retrograde approach seems safe and feasible in inoperable/high-risk patients with AS and peripheral vasculopathy, who are neither eligible for surgical valve replacement nor transfemoral percutaneous aortic valve implantation. Further studies are needed to evaluate the long-term efficacy of this new therapy. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - September 20, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Fraccaro, C., Napodano, M., Tarantini, G., Gasparetto, V., Gerosa, G., Bianco, R., Bonato, R., Pittarello, D., Isabella, G., Iliceto, S., Ramondo, A. Tags: Clinical Research Source Type: journals

Decreased aortic growth and middle aortic syndrome in patients with neuroblastoma after radiation therapyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Patients with neuroblastoma who had received RT showed impaired growth of the abdominal aorta. Significant long-term vascular complications occurred in seven patients who received IORT±EBRT. Thus, CT evaluation of patients with neuroblastoma who receive RT should include not only reports of changes in tumor extension, but also documentation of perfusion, and the size and growth of the aorta and its branches over time. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00247-009-1351-1Authors Elizabeth J. Sutton, Harvard University Department of Radiology, Mount Auburn Hospi...
Source: Pediatric Radiology - September 18, 2009 Category: Radiology Tags: Pediatric Radiology Source Type: journals

CVN: Heart MinuteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Heart Minute: Risk Factors for Aortic Stenosis (Source: Cardiosource)
Source: Cardiosource - September 18, 2009 Category: Cardiology Source Type: organizations