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AF-associated stroke ‘a distinct pathophysiologic and clinical entity’Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Strokes associated with atrial fibrillation account for around one-third of the total and tend to be particularly severe, disabling, and likely to recur, research suggests. (Source: MedWire News - Stroke)
Source: MedWire News - Stroke - November 20, 2009 Category: Neurology Source Type: news

Videothoracoscopy for isolated atrial fibrillation ablation through bipolar radiofrequencyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The video-assisted surgery for the treatment of atrial fibrillation is reproducible and safe. There is a heart failure symptom evolution improvement after the surgery. (Source: Arquivos Brasileiros de Cardiologia)
Source: Arquivos Brasileiros de Cardiologia - November 20, 2009 Category: Cardiology Source Type: journals

Results Presented From First Study Reviewing Convergent Approach To Treating Atrial Fibrillation At American Heart Association Scientific SessionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
nContact Surgical, Inc. ("nContact"), a leader in the investigation of devices for minimally-invasive treatment for heart conditions, announced that data from a poster was presented at the American Heart Association Scientific Sessions in Orlando. The study demonstrated that the convergent approach, which combines surgical and electrophysiological expertise, appears to be a good strategy to achieve short term success in patients with long standing persistent atrial fibrillation (AF). (Source: Cardiovascular / Cardiology News From Medical News Today)
Source: Cardiovascular / Cardiology News From Medical News Today - November 20, 2009 Category: Cardiology Tags: Heart Disease Source Type: news

Results Presented From First Study Reviewing Convergent Approach To Treating Atrial Fibrillation At American Heart Association Scientific SessionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
nContact Surgical, Inc. ("nContact"), a leader in the investigation of devices for minimally-invasive treatment for heart conditions, announced that data from a poster was presented at the American Heart Association Scientific Sessions in Orlando. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 20, 2009 Category: Consumer Health News Tags: Heart Disease Source Type: news

[Correspondence] Occlusion of left atrial appendage to treat atrial fibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study shows, via statistical modelling, that a new strategy—occlusion of the left atrial appendage (LAA) with the WATCHMAN device—is non-inferior to warfarin in patients with atrial fibrillation. Does this result mean a “new dawn” in management of these patients? Well perhaps, but if this device is to have a future, we need to understand the complications better so we can reduce them. (Source: LANCET)
Source: LANCET - November 20, 2009 Category: Journals (General) Authors: Patrick A Calvert, Bushra S Rana, David A Begley, Leonard M Shapiro Tags: Correspondence Source Type: journals

[Correspondence] Occlusion of left atrial appendage to treat atrial fibrillation – Author's replyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We appreciate the comments from Patrick Calvert and colleagues. They are extremely relevant and important to the field. (Source: LANCET)
Source: LANCET - November 20, 2009 Category: Journals (General) Authors: David R Holmes Tags: Correspondence Source Type: journals

The impact of concurrent heart failure on prognosis in patients with chronic obstructive pulmonary diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion Heart failure is a strong independent predictor of all-cause mortality in patients with a diagnosis of COPD. (Source: European Journal of Heart Failure)
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Boudestein, L. C.M., Rutten, F. H., Cramer, M. J., Lammers, J. W. J., Hoes, A. W. Tags: PROGNOSIS Source Type: journals

Clinical trials update from the European Society of Cardiology Meeting 2009: AAA, RELY, PROTECT, ACTIVE-I, European CRT survey, German pre-SCD II registry, and MADIT-CRTEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article provides information and a commentary on trials relevant to the pathophysiology, prevention, and treatment of heart failure presented at the annual meeting of the European Society of Cardiology held in Barcelona in 2009. The AAA study does not support the routine use of aspirin for the prevention of vascular events in patients with asymptomatic atherosclerosis. RELY suggests that dabigatran may be more effective than warfarin for the prevention of stroke in patients with atrial fibrillation. Rolofylline was not superior to placebo in improving outcomes in patients with acute heart failure enrolled in the PROTE...
Source: European Journal of Heart Failure - November 19, 2009 Category: Cardiology Authors: Cleland, J. G.F., Coletta, A. P., Yassin, A., Buga, L., Torabi, A., Clark, A. L. Tags: MEETING REPORT Source Type: journals

The Role of Ganglionated Plexi in Apnea-Related Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: This experimental model of apnea shows a reproducible incidence of AF. After neural ablation of the RPA GP or autonomic blockade, AF inducibility was significantly inhibited. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: Muhammad Ghias, Benjamin J. Scherlag, Zhibing Lu, Guodong Niu, Annerie Moers, Warren M. Jackman, Ralph Lazzara, Sunny S. Po Tags: QUARTERLY FOCUS ISSUE: HEART RHYTHM DISORDERS Source Type: journals

Sleep Apnea and Atrial Fibrillation: The Autonomic Link⁎Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The intuitive and postulated links () between the established association of obstructive sleep apnea with atrial fibrillation (AF) are hypertension, diastolic dysfunction, and the resultant long-term atrial remodeling (). However, studies suggest that the relationship between sleep apnea and AF is independent of hypertension, cardiac function, or body mass index. Further, untreated sleep apnea doubles the risk of AF recurrence within 12 months of cardioversion independent of other risk factors (). Thus, is the relationship between sleep apnea and AF an epiphenomenon, or is it truly causative and the linking mechanism is si...
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: Samuel J. Asirvatham, Suraj Kapa Tags: Editorial Comment Source Type: journals

Transesophageal Echocardiography Before Atrial Fibrillation Ablation: Looking Before Cooking⁎Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In many electrophysiology laboratories, atrial fibrillation (AF) is becoming the most common heart rhythm disorder being treated with catheter ablation. Reasons for this include the large numbers of patients with AF, the poor quality of life commonly associated with AF, the limitations of drug therapy, advances in ablation tools and methods, and the increasing number of electrophysiologists trained in the technique. Catheter ablation is now recognized as a legitimate option for patients with symptomatic AF who have failed antiarrhythmic drug therapy (). (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: Bradley P. Knight Tags: Editorial Comment Source Type: journals

A Comparison of Atrial Arrhythmias After Heart or Double-Lung Transplantation at a Single Center: Insights Into the Mechanism of Post-Operative Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In heart transplant recipients, AF is uncommon and occurs in the setting of myocardial dysfunction and graft rejection. In contrast, AF is more common after lung transplantation despite the absence of graft rejection and cardiac dysfunction. Pulmonary vein isolation alone cannot explain the discrepancy in AF incidence between heart transplant recipients and double-lung transplant recipients. Cardiac autonomic denervation may have a protective effect for heart transplant patients in the post-operative setting. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: José Dizon, Kimberly Chen, Matthew Bacchetta, Michael Argenziano, Donna Mancini, Angelo Biviano, Joshua Sonett, Hasan Garan Tags: QUARTERLY FOCUS ISSUE: HEART RHYTHM DISORDERS Source Type: journals

Atrial Fibrillation After Major Thoracic Surgery: New Insights Into Underlying Mechanisms⁎Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Atrial fibrillation (AF) is a common complication in patients undergoing major thoracic surgery (). It is most frequently observed acutely after valve surgery and/or coronary artery bypass graft surgery (CABG), but it can also manifest after lung and heart transplantation procedures (). Although mechanisms underlying this unique form of AF have not been adequately elucidated, it is likely that these involve a combination of pericardial inflammation, myocardial ischemia, catecholamine surge, autonomic imbalance, interstitial fluid mobilization, tissue rejection, and so forth (). It is interesting to note that AF is observed...
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: Sanjay Dixit Tags: Editorial Comment Source Type: journals

Atrial Fibrillation at Baseline and During Follow-Up in ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Objectives: The ALLHAT (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial) determined that treatment with amlodipine, lisinopril, or doxazosin was not superior to thiazide-like diuretic (chlorthalidone) in preventing coronary heart disease (CHD) or other cardiovascular events. This subanalysis examines baseline prevalence and in-trial incidence of new-onset atrial fibrillation (AF) or atrial flutter (AFL) and their influence on clinical outcomes.Background: Limited information is available on whether atrial fibrillation incidence is affected differentially by different classes of antihypertensive ...
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: L. Julian Haywood, Charles E. Ford, Richard S. Crow, Barry R. Davis, Barry M. Massie, Paula T. Einhorn, Angela Williard, ALLHAT Collaborative Research Group Tags: QUARTERLY FOCUS ISSUE: HEART RHYTHM DISORDERS Source Type: journals

Role of the CHADS2 Score in the Evaluation of Thromboembolic Risk in Patients With Atrial Fibrillation Undergoing Transesophageal Echocardiography Before Pulmonary Vein IsolationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Objectives: The goals of this study were to determine: 1) if low-risk patients assessed by a CHADS2 score, a clinical scoring system quantifying a risk of stroke in patients with atrial fibrillation (AF), require a routine screening transesophageal echocardiogram (TEE) before pulmonary vein isolation (PVI); and 2) the relationship of a CHADS2 score with left atrial (LA)/left atrial appendage (LAA) spontaneous echo contrast, sludge, and thrombus.Background: There is no clear consensus of whether a screening TEE before catheter ablation of AF should be performed in every patient.Methods: Initial TEEs for pre-PVI of 1,058 AF ...
Source: Journal of the American College of Cardiology - November 19, 2009 Category: Cardiology Authors: Sarinya Puwanant, Brandon C. Varr, Kevin Shrestha, Sarah K. Hussain, W.H. Wilson Tang, Ruvin S. Gabriel, Oussama M. Wazni, Mandeep Bhargava, Walid I. Saliba, James D. Thomas, Bruce D. Lindsay, Allan L. Klein Tags: QUARTERLY FOCUS ISSUE: HEART RHYTHM DISORDERS Source Type: journals

Results From Phase 2b Study On Atrial Fibrillation Agent Reviewed At American Heart AssociationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ARYx Therapeutics, Inc. (NASDAQ:ARYX), a biopharmaceutical company, announced that a review of the results of the Phase 2b clinical trial, PASCAL, testing the efficacy and safety of ARYx's compound for the treatment of atrial fibrillation, budiodarone, was presented today at the American Heart Association meeting in Orlando, Florida. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 19, 2009 Category: Consumer Health News Tags: Heart Disease Source Type: news

Results From Phase 2b Study On Atrial Fibrillation Agent Reviewed At American Heart AssociationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ARYx Therapeutics, Inc. (NASDAQ:ARYX), a biopharmaceutical company, announced that a review of the results of the Phase 2b clinical trial, PASCAL, testing the efficacy and safety of ARYx's compound for the treatment of atrial fibrillation, budiodarone, was presented today at the American Heart Association meeting in Orlando, Florida. (Source: Cardiovascular / Cardiology News From Medical News Today)
Source: Cardiovascular / Cardiology News From Medical News Today - November 19, 2009 Category: Cardiology Tags: Heart Disease Source Type: news

AF-associated stroke ‘a distinct pathophysiologic and clinical entity’Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Strokes associated with atrial fibrillation account for around one-third of the total and tend to be particularly severe, disabling, and likely to recur, research suggests. (Source: MedWire News - Cardiology)
Source: MedWire News - Cardiology - November 19, 2009 Category: Cardiology Source Type: news

NICE guidance on catheter ablation of atrial fibrillation using an epicardial (non-thorascopic) approachEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Heart)
Source: Heart - November 18, 2009 Category: Cardiology Authors: Cappato, R. Tags: Drugs: cardiovascular system, Clinical diagnostic tests Technology and guidelines Source Type: journals

Results From Phase 2b Study on Atrial Fibrillation Agent Reviewed at American Heart AssociationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
FREMONT, Calif., Nov 18, 2009 (BUSINESS WIRE) -- ARYx Therapeutics, Inc. (NASDAQ:ARYX), a biopharmaceutical company, announced that a review of the results of the Phase 2b clinical trial, PASCAL, testing the efficacy and safety of ARYx's... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - November 18, 2009 Category: Pharmaceuticals Source Type: clinical trials

Apixaban: an emerging oral factor Xa inhibitorEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract Apixaban, an oral direct factor Xa inhibitor, is currently in late stage clinical development for the prevention and treatment of thromboembolic diseases. In comparison with current treatment standards for venous thromboembolism (VTE) prophylaxis, apixaban has shown decreased rates of clinically significant bleeding with mixed results in terms of non-inferiority for VTE events. Secondary treatment of VTE with apixaban is currently in phase III clinical study after earlier trials showed comparable safety and efficacy outcomes. The APPRAISE-1 trial, a phase II investigation of apixaban versus placebo ...
Source: Journal of Thrombosis and Thrombolysis - November 18, 2009 Category: Hematology Tags: Journal of Thrombosis and Thrombolysis Source Type: journals

Prevalence, clinical correlates and treatment of permanent atrial fibrillation among the elderly: insights from the first prospective population-based study in rural GreeceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract To investigate the prevalence of permanent atrial fibrillation (AF), its clinical associated conditions and treatment status in the elderly population in rural Greece. 720 people (46.1% males) older than 65 years (mean age: 72.5 ± 5.7 years) living in four villages in rural Greece were screened with an electrocardiogram (response rate: 90.5%) for the presence of permanent AF. They underwent a physical examination, including blood pressure (BP) measurement, and body mass index (BMI) calculation, in addition to an interview about their medical history, physical activity, smoking h...
Source: Journal of Thrombosis and Thrombolysis - November 18, 2009 Category: Hematology Tags: Journal of Thrombosis and Thrombolysis Source Type: journals

RECORD AF: Better Success With Rhythm Control, But No Difference in OutcomesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New registry data presented this week showed that cardiologists are more likely to select rhythm control over rate control for the treatment of atrial fibrillation, and this strategy is more likely to lead to successful treatment of AF than the rate-control–based approach. Both strategies are equivalent in terms of their effect on clinical outcomes. Heartwire (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 18, 2009 Category: Consumer Health News Tags: Cardiology Source Type: news

An Anterior Ablation Line Is Preferred for Perimitral Flutter After Heart TransplantEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report 2 cases where an anterior ablation line was easily performed to eliminate perimitral flutter and produce bidirectional block. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]3) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 18, 2009 Category: Cardiology Authors: BHAVANESH MAKANJEE, GEORGE J. KLEIN, NICHOLAS DERVAL, ALLAN C. SKANES Source Type: journals

Mapping and Isolation of the Pulmonary Veins Using the PVAC CatheterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions:(1) PVAC-guided ablation (i.e., mapping and ablation with a single catheter) results in isolation of all PVs in 73% of the patients. (2) An additional circular mapping catheter is required to increase complete isolation rate to 93% of the patients. (3) Given the esophageal T° rise in almost 50% of patients, safety precautions are needed. (PACE 2009; 1[ndash]11) (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - November 18, 2009 Category: Cardiology Authors: MATTIAS DUYTSCHAEVER, WIM ANNE, GIORGI PAPIASHVILI, YVES VANDEKERCKHOVE, RENE TAVERNIER Source Type: journals

Anesthetic management of a patient with hyperthyroidism due to hydatidiform moleEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report here the perioperative management of hyperthyroidism due to hydatidiform mole. A 53-year-old woman underwent emergency surgery due to suspicion of hydatidiform mole. Tachycardiac atrial fibrillation was detected by electrocardiography at the preoperative examination. No abnormalities were found in blood count, coagulation, biochemical tests, chest radiographs, or respiratory function. General anesthesia with nitrous oxide, oxygen, and sevoflurane, combined with fentanyl and 1% mepivacaine, was administered intermittently from an epidural catheter. Intraoperative events included hypotension and tachycardia, a...
Source: Journal of Anesthesia - November 17, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Which patient undergoing mitral valve surgery should also have the tricuspid repair? [Best evidence topic - Valves]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was ‘Which patient undergoing mitral valve surgery should also have the tricuspid repair?’ Altogether 390 papers were found using the reported search, of which 17 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated. While a general agreement exists for tricuspid valve (TV) repair in cases of severe regurgitation and concomitant multivalvular d...
Source: Interactive CardioVascular and Thoracic Surgery - November 17, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Bianchi, G., Solinas, M., Bevilacqua, S., Glauber, M. Tags: Best evidence topic - Valves Source Type: journals

Monitoring of atrial fibrillation burden after surgical ablation: relevancy of end-point criteria after radiofrequency ablation treatment of patients with lone atrial fibrillation [Institutional report - Arrhythmia]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Studies have shown that continuous rhythm monitoring enables the detection of significantly more atrial fibrillation (AF) episodes than routine follow-up of patients, i.e. based on perception of symptoms or on 24–48 h Holter monitoring. The positive outcome of radiofrequency ablation (RFA) may be easily overestimated, especially in patients with paroxysmal AF. Thirty-three consecutive patients, aged 59.4±8.9 years (range 38–75 years) participated in this study. All patients had documented AF episodes with an AF duration of 9.4±7.1 years (range 1.5–25 years). A new monitor...
Source: Interactive CardioVascular and Thoracic Surgery - November 17, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Beukema, R., Beukema, W. P., Sie, H. T., Misier, A. R., Delnoy, P. P., Elvan, A. Tags: Institutional report - Arrhythmia Source Type: journals

eComment: Monitoring of atrial fibrillation burden after surgical ablation [eComment]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - November 17, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Bockeria, L., Revishvili, A. Sh., Dzhordzhikiya, T. R. Tags: eComment Source Type: journals

A Prospective Randomized Multicenter Comparison on Health-Related Quality of Life: The Value of Add-on Arrhythmia Surgery in Patients with Paroxysmal, Permanent or Persistent Atrial Fibrillation Undergoing Valvular and/or Coronary Bypass SurgeryEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Health-related quality of life in patients with paroxysmal, permanent and persistent atrial fibrillation improves after cardiac surgery regardless of giving add-on surgery or not, but this improvement is presumably more affected by treating the underlying heart disease than by restoring sinus rhythm. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]10) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: H. N. A. M. VAN BREUGEL, F. H. M. NIEMAN, R. E. ACCORD, G. A. P. G. VAN MASTRIGT, J. F. M. A. NIJS, J. L. SEVERENS, R. VRAKKING, J. G. MAESSEN Source Type: journals

A Prospective Study Evaluating the Role of Obesity and Obstructive Sleep Apnea for Outcomes After Catheter Ablation of Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Effect of Obesity and OSA on Outcomes Post AF Ablation. Background: Obesity and obstructive sleep apnea (OSA) have a strong association with atrial fibrillation (AF). The purpose of this study was to prospectively determine the effects of obesity, assessed by the body mass index (BMI) and OSA on the efficacy of catheter ablation of AF. Methods: The patient population consisted of 109 patients (mean age: 60 ± 10 years, 79% male, 67% paroxysmal, mean BMI 28 ± 5 kg/m2) who underwent catheter ablation of AF. Based on BMI, patients were classified as normal ( (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: KARUNA CHILUKURI, DARSHAN DALAL, SHRIRANG GADREY, JOSEPH E. MARINE, EDWIN MACPHERSON, CHARLES A. HENRIKSON, ALAN CHENG, SAMAN NAZARIAN, SUNIL SINHA, DAVID SPRAGG, RONALD BERGER, HUGH CALKINS Source Type: journals

Long-Term Functional and Neurocognitive Recovery in Patients Who Had an Acute Cerebrovascular Event Secondary to Catheter Ablation for Atrial FibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Periprocedural stroke in the setting of catheter ablation for atrial fibrillation is relatively rare. When it occurs, complete functional and neurocognitive recovery over time is the likely outcome for most patients. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6) (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: DIMPI PATEL, SHANE M. BAILEY, ANTHONY J. FURLAN, MARILOU CHING, JONATHAN ZACHAIB, LUIGI DI BIASE, PRASANT MOHANTY, RODNEY P. HORTON, J. DAVID BURKHARDT, JAVIER E. SANCHEZ, JASON D. ZAGRODZKY, G. JOSEPH GALLINGHOUSE, ROBERT SCHWEIKERT, WALID SALIBA, ANDREA Source Type: journals

Validation of Coronary Sinus Activation Pattern During Left Atrial Appendage Pacing for Beat-to-Beat Assessment of Mitral Isthmus Conduction/BlockEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Assessment of Mitral Isthmus. Introduction: Mitral isthmus (MI) ablation for treatment of perimitral flutter is often performed during atrial fibrillation (AF) ablation but is technically challenging. Traditional assessment of MI conduction by left atrial activation mapping while pacing from either side of the line is time-consuming, and cannot be performed during ongoing ablation. Analysis of the coronary sinus (CS) activation pattern during left atrial appendage (LAA) pacing has been proposed as a simpler technique for evaluating MI conduction, enabling beat-to-beat assessment of conduction during ablation procedures and...
Source: Journal of Cardiovascular Electrophysiology - November 17, 2009 Category: Cardiology Authors: JOHN PAISEY, TIM R. BETTS, JOSEPH DE BONO, KIM RAJAPPAN, DAVID TOMLINSON, YAVER BASHIR Source Type: journals

Atrial Flutter Versus Atrial Fibrillation in a General Population: Differences in Comorbidities Associated With Their Respective Onset.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion This study represents the first report to evaluate potential differences in the conditions associated with the development of AFL versus AF. Research into the mechanisms of atrial arrhythmogenesis may lead to improved preventive and therapeutic interventions. PMID: 19920163 [PubMed - as supplied by publisher] (Source: Clin Med Res)
Source: Clin Med Res - November 17, 2009 Category: Research Authors: Mareedu RK, Abdalrahman IB, Dharmashankar KC, Granada JF, Chyou PH, Sharma PP, Smith PN, Hayes JJ, Greenlee RT, Vidaillet H Tags: Clin Med Res Source Type: journals

Prolonged PR intervals were associated with increased risk for atrial fibrillation, pacemaker implantation, and mortality.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19920258 [PubMed - as supplied by publisher] (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - November 17, 2009 Category: Internal Medicine Tags: Ann Intern Med Source Type: journals

Percutaneous closure of the left atrial appendage was noninferior to warfarin in atrial fibrillation.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Authors: PMID: 19920255 [PubMed - as supplied by publisher] (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - November 17, 2009 Category: Internal Medicine Tags: Ann Intern Med Source Type: journals

Troponin Levels Help Predict New-Onset Atrial Fibrillation in Ischaemic Stroke Patients: A Retrospective StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Eur Neurol 2010;63:24-28 (DOI:10.1159/000258679) (Source: European Neurology)
Source: European Neurology - November 16, 2009 Category: Neurology Source Type: journals

RECORD AF: Better success with rhythm control, but no difference in outcomesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New registry data presented this week showed that cardiologists are more likely to select rhythm control over rate control for the treatment of atrial fibrillation, and this strategy is more likely to lead to successful treatment of AF than the rate-control-based approach. Both strategies are equivalent in terms of their effect on clinical outcomes. (Source: theHeart.org)
Source: theHeart.org - November 16, 2009 Category: Cardiology Source Type: info

Comparison of a supra-sternal cardiac output monitor (USCOM) with the pulmonary artery catheterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions In our subjects, there was poor agreement between CO measurements done with the supra-sternal Doppler monitor and PAC. (Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - November 16, 2009 Category: Anesthesiology Authors: Thom, O., Taylor, D. M., Wolfe, R. E., Cade, J., Myles, P., Krum, H., Wolfe, R. Tags: Cardiovascular Source Type: journals

Duke Research Institute launches study to better treat a-fibEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To better study treatments and patient outcomes linked to atrial fibrillation, the Duke Clinical Research Institute has initiated the Outcomes Registry for Better informed Treatment of Atrial Fibrillation. (Source: Cardiovascular Business News)
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news

Duke launches study to better treat a-fibEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
To better study treatments and patient outcomes linked to atrial fibrillation, the Duke Clinical Research Institute has initiated the Outcomes Registry for Better informed Treatment of Atrial Fibrillation. (Source: Cardiovascular Business News)
Source: Cardiovascular Business News - November 16, 2009 Category: Cardiology Tags: Latest News Source Type: news

nContact Announces Initiation of Clinical Trials for the Treatment of Atrial Fibrillation in Open-Chest ProceduresEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
MORRISVILLE, N.C., Nov. 16 (HSMN NewsFeed) -- nContact Surgical, Inc. ("nContact"), a leader in the investigation of devices for non-invasive treatment for heart conditions, today announced the initiation of a clinical trial designed to evaluat... Devices, CardiologynContact Surgical, Numeris, Tethered Coagulation, atrial fibrillation (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - November 16, 2009 Category: Pharmaceuticals Source Type: news

RE-LY on dabigatran for stroke prevention in atrial fibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Consistent reductions in stroke and major bleeding events are achieved with dabigatran when compared with dose-adjusted warfarin in patients with atrial fibrillation. This is irrespective of the International Normalized Ratios achieved. (Source: MedWire News - Stroke)
Source: MedWire News - Stroke - November 16, 2009 Category: Neurology Source Type: news

RE-LY on dabigatran for stroke prevention in atrial fibrillationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Consistent reductions in stroke and major bleeding events are achieved with dabigatran when compared with dose-adjusted warfarin in patients with atrial fibrillation. This is irrespective of the International Normalized Ratios achieved. (Source: MedWire News - Cardiology)
Source: MedWire News - Cardiology - November 16, 2009 Category: Cardiology Source Type: news

Record AF: Clinical outcomes similar with rate-control and rhythm-control strategiesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In recently diagnosed patients with atrial fibrillation, a rhythm-control strategy provides better therapeutic success versus a rate-control strategy, but this difference does not lead to improved clinical outcomes, results from the RecordAF survey show. (Source: MedWire News - Cardiology)
Source: MedWire News - Cardiology - November 16, 2009 Category: Cardiology Source Type: news

Hypertrophic cardiomyopathy in the elderlyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Hypertrophic cardiomyopathy (HCM) is a relatively common genetic cardiac disorder with heterogeneous morphological, functional and clinical features. Although the risk of sudden death and incapacitating symptoms in young patients has been focused upon, the disease has been found with increasing frequency in elderly patients. However, there have been few studies on clinical features of HCM in the elderly. We established a cardiomyopathy registration study in Kochi Prefecture, which is one of the most aged communities in Japan, to provide detailed descriptions of the clinical features of HCM in a community-based patient coho...
Source: Geriatrics and Gerontology International - November 16, 2009 Category: Geriatrics Authors: Toru Kubo, Hiroaki Kitaoka, Makoto Okawa, Masanori Nishinaga, Yoshinori L Doi Source Type: journals

Alternative to Warfarin May Cut Risk of BleedingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dabigatran etexilate does well in trial of atrial fibrillation patients (Source: Forbes.com Health News)
Source: Forbes.com Health News - November 15, 2009 Category: Consumer Health News Source Type: news

Alternative to Warfarin May Cut Risk of BleedingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dabigatran etexilate does well in trial of atrial fibrillation patients Source: HealthDay Related MedlinePlus Topics: Atrial Fibrillation, Blood Thinners, Stroke (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - November 15, 2009 Category: Consumer Health News Source Type: consumer

Undiagnosed AF affects a ‘substantial proportion’ of stroke patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Undiagnosed atrial fibrillation is present in nearly 1 in 10 patients with ischemic stroke, a large cohort study has shown. (Source: MedWire News - Stroke)
Source: MedWire News - Stroke - November 14, 2009 Category: Neurology Source Type: news

Undiagnosed AF affects a ‘substantial proportion’ of stroke patientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Undiagnosed atrial fibrillation is present in nearly 1 in 10 patients with ischemic stroke, a large cohort study has shown. (Source: MedWire News - Cardiology)
Source: MedWire News - Cardiology - November 14, 2009 Category: Cardiology Source Type: news