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Late Pulmonary Valve Replacement in Congenital Heart Disease Patients Without Original Congenital Pulmonary Valve Pathologyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This report describes five cases of patients with a history of congenital heart surgery but no congenital pulmonary valve pathology who required pulmonary valve replacement due to the consequences of prolonged pulmonary regurgitation. Although pulmonary regurgitation may be well tolerated for many years, it is further evidence for the importance of close follow-up assessment and monitoring of young adults with congenital heart disease. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00246-009-9574-3Authors Brian E. Kogon, Emory University School of Medicine, Children’s Healthcare of Atlanta Div...
Source: Pediatric Cardiology - November 14, 2009 Category: Cardiology Tags: Pediatric Cardiology Source Type: journals

Noninvasive Assessment of Pulmonary Artery Flow and Resistance by Cardiac Magnetic Resonance in Congenital Heart Diseases With Unrestricted Left-to-Right Shuntemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Measurement of Qp or left-to-right shunt noninvasively by CMR has potential to predict the PVR in patients with an unrestricted left-to-right shunt and could potentially determine operability without having to undertake invasive testing. (Source: Journal of the American College of Cardiology: Cardiovascular Imaging)
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - November 9, 2009 Category: Radiology Authors: Bell, A., Beerbaum, P., Greil, G., Hegde, S., Toschke, A. M., Schaeffter, T., Razavi, R. Tags: Original Research Source Type: journals

Two-patch repair for atrioventricular septal defect with mitral aneurysm.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We experienced an unusual case of partial atrioventricular septal defect in an elderly patient. A preoperative ultrasonic cardiogram revealed the mitral leaflet pouching toward the right atrium and suggested the presence of a ventricular septal defect underneath the atrioventricular valve. The mitral aneurysm was diagnosed as a septal aneurysm on preoperative ultrasonic cardiogram. A crescent-shaped Dacron patch (InterVascular S. A., La Ciotat Cedex, France) was placed beneath the atrioventricular valve to prevent rupture of the mitral aneurysm and support the anterior mitral leaflet by creating a new annulus. We belie...
Source: The Annals of Thoracic Surgery - September 24, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Imura H, Sakamoto S, Maruyama Y, Ochi M, Shimizu K Tags: Ann Thorac Surg Source Type: journals

Two-Patch Repair for Atrioventricular Septal Defect With Mitral Aneurysm [CASE REPORTS]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We experienced an unusual case of partial atrioventricular septal defect in an elderly patient. A preoperative ultrasonic cardiogram revealed the mitral leaflet pouching toward the right atrium and suggested the presence of a ventricular septal defect underneath the atrioventricular valve. The mitral aneurysm was diagnosed as a septal aneurysm on preoperative ultrasonic cardiogram. A crescent-shaped Dacron patch (InterVascular S. A., La Ciotat Cedex, France) was placed beneath the atrioventricular valve to prevent rupture of the mitral aneurysm and support the anterior mitral leaflet by creating a new annulus. We believe t...
Source: The Annals of Thoracic Surgery - September 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Imura, H., Sakamoto, S.-i., Maruyama, Y., Ochi, M., Shimizu, K. Tags: Congenital - acyanotic CASE REPORTS Source Type: journals

Journal Scan: Left Ventricular Morphology Influences Mortality After the Norwood Operation (Heart 2009;95:1238-1244.)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A retrospective review was performed at a single center. Patients with HLHS undergoing stage I Norwood procedures were identified. Exclusion criteria included heterotaxy syndrome, unbalanced atrioventricular septal defect, ventricular septal defect greater than 2 mm, and critical aortic stenosis wit. . . (Source: Cardiosource)
Source: Cardiosource - September 17, 2009 Category: Cardiology Source Type: organizations

Spectrum of congenital heart defects in Croatiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  The aim of our study was to investigate the incidence of congenital defects in children born in Croatia during a period of 5 years, its association with extracardiac malformations, its treatment, and outcome. Medical information about the patients was obtained from 14 paediatric cardiology centres that cover the whole country. Diagnosis was made by clinical findings, electrocardiography, chest X-ray, echocardiography, catheterisation, or autopsy. Between October 1, 2002 and October 1, 2007, there were 205,051 live births in Croatia, 1,480 of which were patients diagnosed with congenital heart d...
Source: European Journal of Pediatrics - September 16, 2009 Category: Pediatrics Tags: European Journal of Pediatrics Source Type: journals

Pulmonary stenosis development and reduction of pulmonary arterial hypertension in atrioventricular septal defect: a case reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A 24-year-old patient was admitted for dyspnoea and syncope. He had a previous history of complete atrio-ventricular septal defect and trisomy 21.At the age of 6 months, in 1984, cardiac catheterization revealed a quasi-systemic pulmonary arterial hypertension with a bidirectional shunt corresponding to an Eisenmenger syndrome. Corrective cardiac surgery was not performed at this time because surgical risk was considered too high. Until the age of 20 years old, he showed few symptoms while under medical treatment. But since 2006, his functional status became worse with an increased dyspnoea , syncopes, and severe cyanosis....
Source: Journal of Cardiothoracic Surgery - September 15, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Emeline BarthHelene BouvaistStephanie MarliereGerard NinetGerald Vanzetto Source Type: journals

Microarray based analysis of 3p25-p26 deletions (3p- syndrome)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Distal deletion of chromosome 3p25-pter (3p- syndrome) produces a distinct clinical syndrome characterized by low birth weight, mental retardation, telecanthus, ptosis, and micrognathia. Congenital heart disease (CHD), typically atrioventricular septal defect (AVSD) occurs in about a third of patients. Previously we reported on an association between the presence of CHD and the proximal extent of the deletion such that a CHD susceptibility gene was mapped between D3S1263 and D3S3594. In addition, we and others have suggested several candidate genes for the psychomotor retardation usually seen with constitutional 3p25 delet...
Source: American Journal of Medical Genetics Part A - September 15, 2009 Category: Genetics & Stem Cells Authors: Salwati Shuib, Dominic McMullan, Eleanor Rattenberry, Richard M. Barber, Fatimah Rahman, Malgosia Zatyka, Cyril Chapman, Fiona Macdonald, Farida Latif, Val Davison, Eamonn R. Maher Source Type: journals

Isolated Cleft of the Mitral Valve: Distinctive Features and Surgical Management [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Echocardiographic description of isolated cleft of the mitral valve is not always as accurate as intraoperative analysis. This is a distinct morphologic entity from the cleft of the left-sided valve of atrioventricular septal defect, and seems associated with a strong female predominance, with various cardiac and extracardiac features. Surgical repair is successful with excellent midterm results. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - August 30, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Abadir, S., Fouilloux, V., Metras, D., Ghez, O., Kreitmann, B., Fraisse, A. Tags: Congenital - acyanotic ORIGINAL ARTICLES: PEDIATRIC CARDIAC Source Type: journals

Isolated cleft of the mitral valve: distinctive features and surgical management.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Echocardiographic description of isolated cleft of the mitral valve is not always as accurate as intraoperative analysis. This is a distinct morphologic entity from the cleft of the left-sided valve of atrioventricular septal defect, and seems associated with a strong female predominance, with various cardiac and extracardiac features. Surgical repair is successful with excellent midterm results. PMID: 19699908 [PubMed - in process] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - August 25, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Abadir S, Fouilloux V, Metras D, Ghez O, Kreitmann B, Fraisse A Tags: Ann Thorac Surg Source Type: journals

Partial atrioventricular septal defect in the fetus: diagnostic features and associations in a multicenter series of 30 cases.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: We describe the key echocardiographic features of pAVSD in the fetus. In addition, we have confirmed that the association with trisomy 21 holds also for pAVSD, though to a lesser extent, with a 12.5% association rate in this series. In the fetus, pAVSD seems to be associated with a high rate of chromosomal/non-chromosomal syndromic conditions, including skeletal dysplasias. Inutero, aortic coarctation represents the most frequently associated cardiac lesion (13.3%). Copyright (c) 2009 ISUOG. Published by John Wiley & Sons, Ltd. PMID: 19705406 [PubMed - as supplied by publisher] (Source: The Ultrasound ...
Source: The Ultrasound Review of Obstetrics and Gynecology - August 23, 2009 Category: Radiology Authors: Paladini D, Volpe P, Sglavo G, Russo MG, De Robertis V, Penner I, Nappi C Tags: Ultrasound Obstet Gynecol Source Type: journals

Prevalence of congenital heart defects in carriers of Down syndrome in the municipality of Pelotas, Brazil.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: The prevalence of Down syndrome and congenital heart defect in our region is similar to the rates found by other authors; therefore, we highlight the importance of diagnostic suspicion and early referral by pediatricians to cardiac evaluation. Another relevant aspect is the small number of patients who underwent karyotype testing. In addition, the number of associated malformations was lower than that found by other authors. PMID: 19662319 [PubMed - as supplied by publisher] (Source: Jornal de Pediatria)
Source: Jornal de Pediatria - August 5, 2009 Category: Pediatrics Authors: Vilas Boas LT, Albernaz EP, Costa RG Tags: J Pediatr (Rio J) Source Type: journals

Med Sci Monit 2009; 15(8):CR409-412 "Down’s syndrome and the pattern of congenital heart disease in a community with high parental consanguinity"email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: A slightly higher frequency of CHD was documented in DS children from this population with a high consanguineous marriage rate. The frequencies of specific lesions were similar to those reported locally and internationally; VSD was the most frequently detected in this study. Interesting was the predominance of left-right shunt lesions and the relative rarity of cyanotic and complex CHD in this DS population. (Source: Medical Science Monitor)
Source: Medical Science Monitor - July 31, 2009 Category: Research Tags: Original article Source Type: journals

Modified single-patch technique: Repairing complete atrioventricular septal defectemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Carl Lewis Backer, Sunjay Kaushal, Constantine MavroudisAnnals of Pediatric Cardiology 2009 2(1):51-54 (Source: Annals of Pediatric Cardiology)
Source: Annals of Pediatric Cardiology - July 30, 2009 Category: Cardiology Authors: Carl Lewis Backer, Sunjay Kaushal, Constantine Mavroudis Source Type: journals

Surgery for complete atrioventricular septal defect: Is a uniform strategy applicable?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Sachin Talwar, Shiv Kumar Choudhary, Balram AiranAnnals of Pediatric Cardiology 2009 2(1):58-60 (Source: Annals of Pediatric Cardiology)
Source: Annals of Pediatric Cardiology - July 30, 2009 Category: Cardiology Authors: Sachin Talwar, Shiv Kumar Choudhary, Balram Airan Source Type: journals

Replyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Discussion section, there were no infants with an atrioventricular septal defect in our study, and thus the potential “added value” of ECG with regard to this diagnosis could not be demonstrated. There were also no infants in our study with tricuspid atresia or Wolff-Parkinson-White syndrome. Our study population (n = 201) was an unselected group of consecutively enrolled neonates seen in an outpatient setting for a murmur assessment, and we believe this is representative of neonates referred to pediatric cardiology programs. (Source: The Journal of Pediatrics)
Source: The Journal of Pediatrics - July 22, 2009 Category: Pediatrics Authors: Andrew S. Mackie, Luc C. Jutras, Adrian B. Dancea, Charles V. Rohlicek, Robert Platt, Marie- J. Béland Tags: Letters to the Editor Source Type: journals

Recurrence of Congenital Heart Defects in Families.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions-Specific CHDs showed highly variable but strong familial clustering in first-degree relatives, ranging from 3-fold to 80-fold compared with the population prevalence, whereas the crossover risks between dissimilar cases of CHD were weaker. Family history of any CHD among first-degree relatives accounted for a small proportion of CHD cases in the population. PMID: 19597048 [PubMed - as supplied by publisher] (Source: Circulation)
Source: Circulation - July 12, 2009 Category: Cardiology Authors: Oyen N, Poulsen G, Boyd HA, Wohlfahrt J, Jensen PK, Melbye M Tags: Circulation Source Type: journals

Results of surgical repair of atrioventricular septal defect with double-orifice left atrioventricular valveemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: Atrioventricular septal defect with double-orifice left atrioventricular valve can be repaired with low mortality. However, double-orifice left atrioventricular valve is a predictor for reoperation. The accessory orifice is often competent and should then be left untouched. If regurgitation of the accessory orifice is present, this is best managed with suture or patch closure. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - June 28, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Gerard J.F. Hoohenkerk, Arnold C.G. Wenink, Paul H. Schoof, Dave R. Koolbergen, Eline F. Bruggemans, Mary Rijlaarsdam, Mark G. Hazekamp Tags: Congenital Heart Disease Source Type: journals

Biventricular repair in unbalanced atrioventricular septal defectemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present the case of a 2.5 year-old child with unbalanced atrioventricular septal defect due to a small left ventricle (LV) (mitral annulus of 10mm and a 0.4 ratio in relation to the tricuspid annulus, LVDD: 17 mm, LV Vd2: 15 ml/m² and LV/RV long-axis ratio of 0.71); he had a favorable outcome after biventricular surgical repair. Normal LV development was observed three months after the operation (mitral annulus of 22 mm, with a 0.84 ratio in relation to the tricuspid annulus, and LVDD of 30 mm). Current parameters for utilization of the hypoplastic ventricle are discussed.Presenta evolución favorable después de corre...
Source: Arquivos Brasileiros de Cardiologia - June 28, 2009 Category: Cardiology Source Type: journals

Acquired left atrial-to-right ventricular shunt with mitral valve incompetence: a rare sequela after repair of atrioventricular septal defect.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Acquired left ventricular-to-right atrial communication is encountered periodically. This condition is chiefly attributable to surgical mishaps, trauma, endocarditis, or endomyocardial biopsy. In a few instances, a Gerbode-like defect develops after the repair of an atrioventricular septal defect. Our search of the worldwide medical literature revealed just 1 report of a "mirror" occurrence of a Gerbode-like defect: a shunt between the left atrium and the right ventricle. Herein, we present the case of a 22-year-old woman who had severe mitral valve incompetence accompanying an acquired shunt between the left atrium an...
Source: Texas Heart Institute Journal - June 27, 2009 Category: Cardiology Authors: Mohapatra S, Minhas HS, Virmani S, Mishra BB, Mukherjee K, Banerjee A Tags: Tex Heart Inst J Source Type: journals

Modified single-patch technique: Repairing complete atrioventricular septal defectemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Backer Carl Lewis, Kaushal Sunjay, Mavroudis ConstantineAnnals of Pediatric Cardiology 2009 2(1):51-54 (Source: Annals of Pediatric Cardiology)
Source: Annals of Pediatric Cardiology - June 25, 2009 Category: Cardiology Authors: Backer Carl Lewis, Kaushal Sunjay, Mavroudis Constantine Source Type: journals

Surgery for complete atrioventricular septal defect: Is a uniform strategy applicable?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Talwar Sachin, Choudhary Shiv Kumar, Airan BalramAnnals of Pediatric Cardiology 2009 2(1):58-60 (Source: Annals of Pediatric Cardiology)
Source: Annals of Pediatric Cardiology - June 25, 2009 Category: Cardiology Authors: Talwar Sachin, Choudhary Shiv Kumar, Airan Balram Source Type: journals

[Institutional report - Congenital] Outcome after reoperation for atrioventricular septal defect repairemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This report describes our experience in 59 patients who underwent reoperation after AVSD repair, between 1977 and 2008. Thirty-one patients had a PAVSD, 28 had a CAVSD. Mean interval between initial repair and reoperation was 10±11 years (PAVSD vs. CAVSD: 13±12 vs. 6±9 years, P=0.063). Reoperations were required for left atrioventricular valve regurgitation (LAVVR) in 53 patients (combined with right atrioventricular valve regurgitation in 10, atrial septal defect (ASD) in 11, ventricular septal defect (VSD) in 7, left ventricular outflow tract (LVOT) obstruction in 1, and aortic valve stenos...
Source: Interactive CardioVascular and Thoracic Surgery - June 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Birim, O., van Gameren, M., de Jong, P. L., Witsenburg, M., van Osch-Gevers, L., Bogers, A. J.J.C. Tags: Institutional report - Congenital Source Type: journals

[eComment] eComment: Discrete subaortic stenosis following repair of atrioventricular septal defectsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - June 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Edwin, F., Tettey, M. M., Entsua-Mensah, K., Frimpong-Boateng, K. Tags: eComment Source Type: journals

Outcome after reoperation for atrioventricular septal defect repair [Institutional report - Congenital]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This report describes our experience in 59 patients who underwent reoperation after AVSD repair, between 1977 and 2008. Thirty-one patients had a PAVSD, 28 had a CAVSD. Mean interval between initial repair and reoperation was 10±11 years (PAVSD vs. CAVSD: 13±12 vs. 6±9 years, P=0.063). Reoperations were required for left atrioventricular valve regurgitation (LAVVR) in 53 patients (combined with right atrioventricular valve regurgitation in 10, atrial septal defect (ASD) in 11, ventricular septal defect (VSD) in 7, left ventricular outflow tract (LVOT) obstruction in 1, and aortic valve stenos...
Source: Interactive CardioVascular and Thoracic Surgery - June 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Birim, O., van Gameren, M., de Jong, P. L., Witsenburg, M., van Osch-Gevers, L., Bogers, A. J.J.C. Tags: Institutional report - Congenital Source Type: journals

eComment: Discrete subaortic stenosis following repair of atrioventricular septal defects [eComment]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - June 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Edwin, F., Tettey, M. M., Entsua-Mensah, K., Frimpong-Boateng, K. Tags: eComment Source Type: journals

Results of Left Atrioventricular Valve Reoperations Following Previous Repair of Atrioventricular Septal Defectsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: LAVVR results in significant clinical improvement and lasting recovery in ventricular chamber function and size. Valve repair offers survival advantage and should be aggressively attempted; however, it is only achievable in 50% of cases. Valve replacement is necessary in cases associated with complex LAVV morphology or following repair failure. At intermediate follow-up, patients continue to be at risk of major valve-related morbidity, requirement for re-intervention, and cardiac death. (J Card Surg ****;**:**-**) (Source: Journal of Cardiac Surgery)
Source: Journal of Cardiac Surgery - June 14, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Bahaaldin Alsoufi, Zohair Al-Halees, Fareed Khouqeer, Charles C. Canver, Ghassan Siblini, Elias Saad, Ahmed Sallehuddin Source Type: journals

RTN3 inducing apoptosis is modulated by an adhesion protein CRELD1.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Reticulon3 (RTN3), as a member of the reticulon family, is generally regarded as a novel human apoptosis-inducing protein. But the extensional role of RTN3 remains virtually unknown. Herein, we showed that cysteine rich with EGF like domains 1(CRELD1), a cell adhesion molecule played a critical role in atrioventricular septal defects and it had mutual effect with RTN3 in vitro. Furthermore, we discovered that ectopic CRELD1 could interact with ectopic or endogenous RTN3. CRELD1 bound with RTN3 so as to increase the localization of RTN3 on the plasma membrane and decreased the apoptotic activity of RTN3 moderately. More...
Source: Molecular and Cellular Biochemistry - June 11, 2009 Category: Biochemistry Authors: Xiang R, Zhao S Tags: Mol Cell Biochem Source Type: journals

Left cardiac isomerism in the Sonic hedgehog null mouse.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study, we describe the morphology of the atrial chambers and atrioventricular junctions of the Shh null mouse heart. We demonstrate that the essential phenotypic feature is isomerism of the left atrial appendages, in combination with an atrioventricular septal defect and a common atrioventricular junction. These malformations are known to be frequent in humans with left isomerism. To confirm the presence of left isomerism, we show that Pitx2c, a recognized determinant of morphological leftness, is expressed in the Shh null mutants on both the right and left sides of the inflow region, and on both sides of the solit...
Source: Journal of Anatomy - May 31, 2009 Category: Anatomy Authors: Hildreth V, Webb S, Chaudhry B, Peat JD, Phillips HM, Brown N, Anderson RH, Henderson DJ Tags: J Anat Source Type: journals

[Pulmonary artery banding operation and results of terminal biventricular and univentricular repair]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: Pulmonary artery banding operation has still a significant role in the palliation of certain congenital cardiac anomalies. Outcome of patients who are candidates for biventricular repair is better than the univentricular repairs. PMID: 19520656 [PubMed - in process] (Source: Anadolu Kardiyol Der...)
Source: Anadolu Kardiyol Der... - May 31, 2009 Category: Cardiology Authors: Erek E, Yalçinbaş YK, Türkekul Y, Oztarhan K, Colakoğlu A, Saygili A, Sarioğlu A, Sarioğlu T Tags: Anadolu Kardiyol Derg Source Type: journals

[ORIGINAL ARTICLES: PEDIATRIC CARDIAC] Reoperations After Initial Repair of Complete Atrioventricular Septal Defectemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions The most common indication for reoperation after CAVSD repair is LAVV regurgitation. LAVV re-repair offers good durability, and LAVV replacement does not preclude additional reoperations. Long-term survival is very good despite need for multiple reoperations in some. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Stulak, J. M., Burkhart, H. M., Dearani, J. A., Schaff, H. V., Cetta, F., Barnes, R. D., Puga, F. J. Tags: Congenital - cyanotic ORIGINAL ARTICLES: PEDIATRIC CARDIAC Source Type: journals

Reoperations After Initial Repair of Complete Atrioventricular Septal Defect [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions The most common indication for reoperation after CAVSD repair is LAVV regurgitation. LAVV re-repair offers good durability, and LAVV replacement does not preclude additional reoperations. Long-term survival is very good despite need for multiple reoperations in some. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - May 20, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Stulak, J. M., Burkhart, H. M., Dearani, J. A., Schaff, H. V., Cetta, F., Barnes, R. D., Puga, F. J. Tags: Congenital - cyanotic ORIGINAL ARTICLES: PEDIATRIC CARDIAC Source Type: journals

[Original articles] Mid-term results of right axillary incision for the repair of a wide range of congenital cardiac defectsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The right axillary incision provides a quality of repair for various congenital defects similar to that obtained by using standard surgical approaches. Because of its deceitful location, and the camouflaging effect of being hidden by the resting arm, it has superior cosmetic appeal compared to conventional incisions. The incision does not interfere with subsequent development of the thorax or the breast (in case of females). (Source: European Journal of Cardio-Thoracic Surgery)
Source: European Journal of Cardio-Thoracic Surgery - April 30, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Dave, H. H., Comber, M., Solinger, T., Bettex, D., Dodge-Khatami, A., Pretre, R. Tags: Congenital - acyanotic, Minimally invasive surgery Original articles Source Type: journals

[Review] Current options and outcomes for the management of atrioventricular septal defectemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article reviews our current understanding of the morphology of this defect, aspects of diagnosis and surgical treatment options. (Source: European Journal of Cardio-Thoracic Surgery)
Source: European Journal of Cardio-Thoracic Surgery - April 30, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Shuhaiber, J. H., Ho, S. Y., Rigby, M., Sethia, B. Tags: Congenital - acyanotic, Congenital - cyanotic Review Source Type: journals

Oral contraceptives/prednisone: Fatal thromboembolism in a patient with repaired atrioventricular septal defect: case report.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Page: 33 (Source: Reactions Weekly)
Source: Reactions Weekly - April 29, 2009 Category: Drugs & Pharmacology Tags: HTML Source Type: journals

Oral contraceptives/prednisone: Fatal thromboembolism in a patient with repaired atrioventricular septal defect: case reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Reactions)
Source: Reactions - April 26, 2009 Category: Drugs & Pharmacology Tags: Short communication Source Type: journals

Torsades de Pointes in atrioventricular septal defectemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: Complete heart block is a known association of atrioventricular septal defect. Bradycardia secondary to heart block can lead to abnormal QT prolongation and precipitate Torsades de Pointes and arrest. Here, a case report of these events is described, together with a brief literature review. (Source: International Journal of Cardiology)
Source: International Journal of Cardiology - April 24, 2009 Category: Cardiology Authors: Sukhjinder Nijjer, Steven White, Michael A. Gatzoulis Tags: Online Letters to the Editor Source Type: journals

[ORIGINAL ARTICLES: PEDIATRIC CARDIAC] Common Arterial Trunk With Atrioventricular Septal Defect: New Observations Pertinent to Repairemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Owing to the unique ventriculoarterial connection, the surgeon, considering anatomical repair, needs to pay attention to the anterosuperior margin of the ventricular scoop, which determines the adequacy of left ventricular outflow size. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - April 21, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Adachi, I., Ho, S. Y., Bartelings, M. M., McCarthy, K. P., Seale, A., Uemura, H. Tags: Congenital - cyanotic ORIGINAL ARTICLES: PEDIATRIC CARDIAC Source Type: journals

Common Arterial Trunk With Atrioventricular Septal Defect: New Observations Pertinent to Repair [ORIGINAL ARTICLES: PEDIATRIC CARDIAC]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Owing to the unique ventriculoarterial connection, the surgeon, considering anatomical repair, needs to pay attention to the anterosuperior margin of the ventricular scoop, which determines the adequacy of left ventricular outflow size. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - April 20, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Adachi, I., Ho, S. Y., Bartelings, M. M., McCarthy, K. P., Seale, A., Uemura, H. Tags: Congenital - cyanotic ORIGINAL ARTICLES: PEDIATRIC CARDIAC Source Type: journals

Cardiac Surgery in Patients with Trisomy 18email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Cardiac surgery is infrequently but increasingly being used to repair congenital heart defects associated with trisomy 18. The clinical details of trisomy 18 patients undergoing cardiac surgery have rarely been reported. Seventeen patients with trisomy 18 and serious cardiac symptoms underwent cardiac surgery in our institution. Age at surgery ranged from 7 to 258 days (median, 66 days). One patient had an atrioventricular septal defect and coarctation of the aorta. The remaining patients had ventricular septal defects, including four patients with coarctation of the aorta. Fourteen patien...
Source: Pediatric Cardiology - April 2, 2009 Category: Cardiology Tags: Pediatric Cardiology Source Type: journals

Combination of aortopulmonary window and complete atrioventricular septal defect in a patient with heterotaxy syndrome.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A rare combination of aortopulmonary window and complete atrioventricular septal defect diagnosed in a 2-month-old infant with heterotaxy syndrome is presented. Being aware of this combination of cardiac anomalies before surgical intervention is crucial for perioperative anesthetic technique and preservation of the myocardium. PMID: 19324181 [PubMed - in process] (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - April 1, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Mirzaaghayan MR, Shabanian R, Kiani A Tags: Ann Thorac Surg Source Type: journals

Transannular patching is a valid alternative for tetralogy of Fallot and complete atrioventricular septal defect repair.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Tetralogy of Fallot associated with complete atrioventricular septal defect can be corrected at low risk with favorable intermediate survival. Use of right ventricle-to-pulmonary artery conduit can be avoided in two thirds of patients with no impact on survival, possibly improving overall freedom from reintervention. PMID: 19327518 [PubMed - in process] (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 1, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Brancaccio G, Michielon G, Filippelli S, Perri G, Di Carlo D, Iorio FS, Oricchio G, Iacobelli R, Amodeo A, Di Donato RM Tags: J Thorac Cardiovasc Surg Source Type: journals

[Original articles] Outcomes following surgical repair of aortic arch obstructions with associated cardiac anomaliesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The type of associated intracardiac anomalies with arch obstruction influenced postoperative outcomes. Although both approaches could achieve good results, our data suggest that single-stage repair for arch obstruction with VSD may be associated with better survival, and is therefore recommended. (Source: European Journal of Cardio-Thoracic Surgery)
Source: European Journal of Cardio-Thoracic Surgery - March 30, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Kobayashi, M., Ando, M., Wada, N., Takahashi, Y. Tags: Congenital - acyanotic, Congenital - cyanotic Original articles Source Type: journals

[CASE REPORTS] Combination of Aortopulmonary Window and Complete Atrioventricular Septal Defect in a Patient With Heterotaxy Syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A rare combination of aortopulmonary window and complete atrioventricular septal defect diagnosed in a 2-month-old infant with heterotaxy syndrome is presented. Being aware of this combination of cardiac anomalies before surgical intervention is crucial for perioperative anesthetic technique and preservation of the myocardium. (Source: The Annals of Thoracic Surgery)
Source: The Annals of Thoracic Surgery - March 25, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Mirzaaghayan, M. R., Shabanian, R., Kiani, A. Tags: Congenital - cyanotic CASE REPORTS Source Type: journals

[Institutional report - Congenital] Surgical outcomes of the modified single-patch technique in complete atrioventricular septal defectemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We examined the usefulness of the modified single-patch technique for the surgical management of complete atrioventricular septal defect (AVSD). Sixty-one patients undergoing total correction for complete AVSD from January 1997 to December 2006 were classified to the modified single-patch technique group (18 patients) and the classical one-/two-patch technique group (43 patients). The surgical outcomes of the modified single-patch technique were compared with those of the classical-patch technique. Aortic cross-clamp time was shorter in the modified single-patch technique group (110.8±27.5 min vs. 134.4±...
Source: Interactive CardioVascular and Thoracic Surgery - March 20, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Jeong, I. S., Lee, C.-H., Lee, C., Lim, H. G., Kim, I. S., Youn, H. C., Hwang, S. W., Seo, H.-J. Tags: Institutional report - Congenital Source Type: journals

National time trends in congenital heart defects, Denmark, 1977-2005.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: CHD birth prevalence increased from the beginning of the 1980s but stabilized in the late 1990s. PMID: 19249416 [PubMed - as supplied by publisher] (Source: American Heart Journal)
Source: American Heart Journal - March 1, 2009 Category: Cardiology Authors: Oyen N, Poulsen G, Boyd HA, Wohlfahrt J, Jensen PK, Melbye M Tags: Am Heart J Source Type: journals

Specific issues after surgical repair of partial atrioventricular septal defect: Actuarial survival, freedom from reoperation, fate of the left atrioventricular valve, prevalence of left ventricular outflow tract obstruction, and other events.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Detailed assessment of the valve morphology and individualized valvuloplasty techniques improves the long-term survival after repair of partial atrioventricular septal defects. The presence of grossly malformed left valvular apparatus, pulmonary artery hypertension, and moderate-to-severe left atrioventricular valve regurgitation are independent predictors of death and defect-related morbidity after surgical repair. PMID: 19258063 [PubMed - in process] (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - March 1, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Chowdhury UK, Airan B, Malhotra A, Bisoi AK, Kalaivani M, Govindappa RM, Venugopal P Tags: J Thorac Cardiovasc Surg Source Type: journals

National time trends in congenital heart defects, Denmark, 1977-2005.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: CHD birth prevalence increased from the beginning of the 1980s but stabilized in the late 1990s. PMID: 19249416 [PubMed - in process] (Source: American Heart Journal)
Source: American Heart Journal - March 1, 2009 Category: Cardiology Authors: Oyen N, Poulsen G, Boyd HA, Wohlfahrt J, Jensen PK, Melbye M Tags: Am Heart J Source Type: journals

Pericardial patch repair of the left atrioventricular valve in atrioventricular septal defect: long-term changes in the patchemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: A 31-year-old woman with partial atrioventricular septal defect underwent left atrioventricular valve (LAVV) replacement. Her initial repair was at 8 years of age. At 23 years of age, she underwent reoperation due to a combination of severe left ventricular outlet obstruction and moderate LAVV regurgitation. At that reoperation, she had a Dacron patch enlargement of the infundibular septum and repair of her LAVV with a xenograft (bovine) pericardial patch sutured into the superior bridging leaflet. LAVV replacement was required 8 years later because of valve insufficiency. There was a perforation in the patch wit...
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Adriana Luk, Eric Ahn, Gursharan S. Soor, William G. Williams, Melitta Mezody, Jagdish Butany Tags: Case Reports Source Type: journals

Cardiac abnormalities of Sudanese patients with Down's syndrome and their short-term outcome.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: The pattern of CHD in Sudanese patients with DS was comparable with that in the literature, including the rare occurrence of AVSD with intact atrial septum. In addition, we described an unreported association with right atrioventricular valve malformation. Although there was a significant delay in diagnosis and surgery, surgical results and short-term follow up were good. PMID: 19421645 [PubMed - in process] (Source: Cardiovascular Journal of Africa)
Source: Cardiovascular Journal of Africa - March 1, 2009 Category: Cardiology Authors: Ali SK Tags: Cardiovasc J Afr Source Type: journals