Cardiac Sarcoma
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29 records returned
Surgical treatment of primary cardiac sarcomas.
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PMID: 19876427 [PubMed - in process] (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - October 31, 2009 Category: Cardiology Authors: Blackmon SH, Reardon MJ Tags: Tex Heart Inst J Source Type: journals
Treatment and Outcomes in Adult Patients with Primary Cardiac Sarcoma: The British Columbia Cancer Agency Experience
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Conclusions Patients with nonmetastatic cardiac sarcoma amenable to complete resection experienced improved survival. However, the high
overall rates of disease progression and mortality highlight the need for more effective local and systemic treatments that
may be used in conjunction with surgery to improve patient outcomes.
Content Type Journal ArticleCategory Bone and Soft Tissue SarcomasDOI 10.1245/s10434-009-0734-8Authors
Pauline T. Truong, British Columbia Cancer Agency Radiation Therapy Program, Vancouver Island Centre Victoria BC CanadaStuart O. Jones, British Columbia Cancer Agency Radiation...
Source: Annals of Surgical Oncology - October 15, 2009 Category: Cancer & Oncology Tags: Annals of Surgical Oncology Source Type: journals
Primary sarcoma of the right ventricle: surgical and adjuvant therapy
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We describe surgical and adjuvant therapeutic management of a right ventricular (RV) sarcoma and pulmonary artery occlusion.
Echocardiographic evaluation of a 39-year-old man with exertional dyspnea revealed a tumor mass in the right ventricle, pulmonary
trunk, and bilateral pulmonary arteries. The tumor was resected with concomitant pulmonary valvotomy, but the resection was
incomplete. The RV outflow was reconstructed with an allograft patch, and a stentless valve was implanted for pulmonary valvular
function. The pulmonary trunk and arteries were enlarged with allograft patches. The tumor was undifferentiated sarcom...
Source: General Thoracic and Cardiovascular Surgery - September 23, 2009 Category: Cardiovascular & Thoracic Surgery Tags: General Thoracic and Cardiovascular Surgery Source Type: journals
Delayed left ventricular free-wall rupture after cardiac sarcoma resection.
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We report the case of a 38-year-old woman who underwent cardiac sarcoma resection and presented later with spontaneous left ventricular free-wall rupture. The original tumor resection required autotransplantation and a transmitral approach, including partial resection of the inner left ventricular wall. Although the patient did well postoperatively, 3 weeks later she developed a large pericardial effusion with tamponade. Intraoperatively, a portion of the left ventricular free wall ruptured and required repair with a Dacron patch. The patient recovered and was discharged from the hospital 3 weeks later. To our knowledge, t...
Source: Texas Heart Institute Journal - June 27, 2009 Category: Cardiology Authors: Bruckner BA, Saharia A, Aburto J, Reardon MJ Tags: Tex Heart Inst J Source Type: journals
Imprint cytology of primary cardiac sarcomas: a report of 3 cases
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This study elucidated the cellular characteristics and immunohistochemistry for cardiac sarcomas using imprint smears as an aid to cytopathologic diagnosis. (Source: Annals of Diagnostic Pathology)
Source: Annals of Diagnostic Pathology - May 21, 2009 Category: Pathology Authors: Nobuzo Iwa, Kazuyoshi Masuda, Chikao Yutani, Tadao K. Kobayashi Tags: Original Contributions Source Type: journals
[Case report - Cardiac general] Prolonged survival with left atrial spindle cell sarcoma
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This report describes a 48-year-old gentleman who underwent multiple surgeries to achieve an 11-year survival since the diagnosis. The operative techniques have been described. (Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - May 14, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Modi, A., Lipnevicius, A., Moorjani, N., Haw, M. Tags: Case report - Cardiac general Source Type: journals
Prolonged survival with left atrial spindle cell sarcoma [Case report - Cardiac general]
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This report describes a 48-year-old gentleman who underwent multiple surgeries to achieve an 11-year survival since the diagnosis. The operative techniques have been described. (Source: Interactive CardioVascular and Thoracic Surgery)
Source: Interactive CardioVascular and Thoracic Surgery - May 13, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Modi, A., Lipnevicius, A., Moorjani, N., Haw, M. Tags: Case report - Cardiac general Source Type: journals
Primary cardiac sarcoma presenting as shock
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We report an adult male who presented to emergency department with shock. Echocardiography
revealed a huge right ventricular mass obstructing the right ventricular outflow tract and he underwent emergency resection
of the mass. Subsequent histopathology confirmed the diagnosis of fibromyxosarcoma. Primary cardiac sarcoma presenting as
circulatory shock is a rare phenomenon.
Content Type Journal ArticleDOI 10.1007/s12055-009-0008-xAuthors
Rangaraj Ramalingam, Sri Jayadeva Institute of Cardiology Department of Cardiology Bangalore 560069 IndiaNagaraja Moorthy, Sri Jayadeva Institute of Cardiology Department of Cardio...
Source: Indian Journal of Thoracic and Cardiovascular Surgery - April 25, 2009 Category: Cardiovascular & Thoracic Surgery Tags: Indian Journal of Thoracic and Cardiovascular Surgery Source Type: journals
Outcomes after surgical resection of cardiac sarcoma in the multimodality treatment era
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Conclusions: Multimodal therapy can achieve reasonable survival for patients with resected cardiac sarcomas. Patients with local tumor recurrence or metastatic disease may still benefit from aggressive treatment. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 2, 2009 Category: Cardiovascular & Thoracic Surgery Authors: Faisal G. Bakaeen, Dawn E. Jaroszewski, David C. Rice, Garret L. Walsh, Ara A. Vaporciyan, Steven S. Swisher, Robert Benjamin, Shanda Blackmon, Michael J. Reardon Tags: Acquired Cardiovascular Disease Source Type: journals
Primary cardiac undifferentiated sarcoma of the right atrium presenting with cardiac tamponade
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This report illustrates the serial imaging of a primary cardiac undifferentiated sarcoma of the right atrium using echocardiography, chest X-ray, and computed tomography. Transthoracic echocardiography on presentation showed an extensive mass of the right atrial free wall with an impending cardiac tamponade. Symptoms were controlled with pericardiocentesis, pericardial window, and radiotherapy but recurred 8 months later with pleural effusion and tumor spread to the great arteries. Primary cardiac sarcoma (PSC) is a rare and aggressive malignancy that is usually diagnosed late due to its nonspecific symptoms. Cytology and ...
Source: Cardiovascular Pathology - March 1, 2009 Category: Cardiology Authors: Poi Keong Kong, Stasinos theodorou, Elisabeth Beran, Hardial Singh, Wadih Dimitri Tags: Case Reports Source Type: journals
An unusual case of spinal column metastasis after orthotopic transplantation for cardiac sarcoma.
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The authors describe a patient who underwent orthotopic cardiac transplantation after an undifferentiated cardiac sarcoma was diagnosed. While receiving immunosuppressive therapy, the patient developed spinal column metastases and cauda equina syndrome requiring surgical decompression and stabilization. This occurred despite an exhaustive search for metastatic disease prior to the transplantation. To the authors' knowledge, this represents the first reported case of an undifferentiated cardiac sarcoma metastasis to the spine. This previously healthy 18-year-old woman presented with a myocardial infarction. Investigatio...
Source: Journal of Neurosurgery.Spine - October 1, 2008 Category: Neurosurgery Authors: McLoughlin GS, Sciubba DM, Ali SK, Weinkauf JG, Fourney DR Tags: J Neurosurg Spine Source Type: journals
Stereotactic radiosurgery for a cardiac sarcoma: a case report.
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We report a case of a 75-year-old man with a pulmonary artery sarcoma, recurrent following surgical resection. To palliate symptoms of this recurrence, he underwent CyberKnife stereotactic radiosurgery with a clinical and radiographic response of his treated disease. No acute or sub-acute toxicity was seen until the patient's death due to metastatic disease 10 weeks following treatment. The feasibility and short-term safety of this technique are reviewed, with emphasis on the stereotactic planning considerations, such as mediastinal organ movement and radiation tolerance.
PMID: 18783285 [PubMed - in process] (Source: T...
Source: Technology in Cancer Research and Treatment - September 13, 2008 Category: Cancer & Oncology Authors: Soltys SG, Kalani MY, Cheshier SH, Szabo KA, Lo A, Chang SD Tags: Technol Cancer Res Treat Source Type: journals
Primary cardiac sarcomas: a clinicopathologic analysis of a series with follow-up information in 17 patients and emphasis on long-term survival.
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Although cardiac sarcomas are rare in comparison to their soft tissue counterparts, they are the second most common type of primary cardiac neoplasm. Of the few hundred cases reported, most has been based on autopsy series. A series of 27 cardiac sarcomas removed at surgery for curative and diagnostic intent were reviewed for clinicopathologic features with correlation to available postoperative follow-up data in 17 patients. There were 6 angiosarcomas, 6 myxofibrosarcomas, 3 malignant peripheral nerve sheath tumors, 3 leiomyosarcomas, 2 synovial sarcomas, 1 epithelioid hemangioendothelioma, 1 chondrosarcoma, 1 osteosa...
Source: Human Pathology - July 3, 2008 Category: Pathology Authors: Zhang PJ, Brooks JS, Goldblum JR, Yoder B, Seethala R, Pawel B, Gorman JH, Gorman RC, Huang JH, Acker M, Narula N Tags: Hum Pathol Source Type: journals
Clinicopathologic study of 24 patients with primary cardiac sarcomas: a 10-year single institution experience.
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In conclusion, angiosarcoma and unclassified sarcomas are the most common sarcomas of the heart accounting for 76%, but rare tumors such as synovial sarcoma and leiomyosarcoma may also occur in this organ. The survival of cardiac sarcomas is poor.
PMID: 18538171 [PubMed - in process] (Source: Human Pathology)
Source: Human Pathology - June 1, 2008 Category: Pathology Authors: Kim CH, Dancer JY, Coffey D, Zhai QJ, Reardon M, Ayala AG, Ro JY Tags: Hum Pathol Source Type: journals
Cardiac granulocytic sarcoma diagnosed by intracardiac echocardiography-guided biopsy.
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A 52-year-old man presented with clinical and echocardiographic signs of cardiac tamponade. A transthoracic echocardiogram revealed a large right atrial mass that obstructed the superior vena cava flow. Cardiac magnetic resonance imaging and computed tomography demonstrated extracardiac tumour invasion of the free atrial wall extending to the right pulmonary hilus. Intracardiac echocardiography-guided biopsy of the tumour revealed the tissue diagnosis-granulocytic sarcoma of the heart. The patient was effectively treated with radiotherapy, chemotherapy and allogeneic haematopoietic stem cell transplantation. He has rem...
Source: International Journal of Hematology - May 24, 2008 Category: Hematology Authors: Koželj M, Zorman D, Mrevlje B, Cernelč P, Zver S Tags: Int J Hematol Source Type: journals
Isolated Left-Sided Metastatic Sarcoma of the Heart with Limb Ischemia. A Case Report
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(Source: JBJS [Am])
Source: JBJS [Am] - May 1, 2008 Category: Orthopaedics Authors: Maheshwari, A. V., Muro-Cacho, C. A., Cohen, J. J., Keisch, M., Klos, R. B., Temple, H. T. Tags: Oncology Case Reports Source Type: journals
Isolated left-sided metastatic sarcoma of the heart with limb ischemia. A case report.
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PMID: 18451405 [PubMed - indexed for MEDLINE] (Source: The Journal of Bone and Joint Surgery. American volume)
Source: The Journal of Bone and Joint Surgery. American volume - May 1, 2008 Category: Orthopaedics Authors: Maheshwari AV, Muro-Cacho CA, Cohen JJ, Keisch M, Klos RB, Temple HT Tags: J Bone Joint Surg Am Source Type: journals
Malignant primary cardiac tumors
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Primary cardiac sarcomas are uncommon. The authors undertook to review the Mayo Clinic's experience with primary cardiac sarcomas consisting of 34 patients seen over a 32-year period.The patient database at the Mayo Clinic was searched to identify patients with malignant tumors of the heart seen during the 32-year period between 1975 and 2007. Thirty-four patients with primary cardiac sarcomas were identified and their medical records reviewed for details pertaining to presenting symptoms, staging modalities, treatment approaches, and outcomes.Of the 34 patients, 17 were men and 17 were women. The median age was 44 years. ...
Source: Cancer - April 21, 2008 Category: Cancer & Oncology Authors: Lijo Simpson, Shaji K. Kumar, Scott H. Okuno, Hartzell V. Schaff, Luis F. Porrata, Jan C. Buckner, Timothy J. Moynihan Source Type: journals
Primary cardiac sarcoma.
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Primary cardiac sarcomas are uncommon entities. The diagnosis of sarcoma is not made preoperatively because of the rarity of the lesion and the nonspecific nature of the signs and symptoms. This is a report of a case of primary sarcoma arising from the left atrium, in a patient who presented with acute dyspnoea; the sarcoma resembled an atrial myxoma on echocardiography.
PMID: 18417846 [PubMed - in process] (Source: Indian Journal of Pathology and Microbiology)
Source: Indian Journal of Pathology and Microbiology - January 1, 2008 Category: Pathology Authors: Khadilkar UN, Harish R, Tantry G, Kumar S, Tiwari A Tags: Indian J Pathol Microbiol Source Type: journals
Low-grade myofibroblastic sarcoma of the heart causing sudden death.
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We present a case of a primary cardiac sarcoma presenting as sudden death in a 5-year-old Asian girl. Pathologic examination of the lesion confirmed that this was an atypical myofibroblastic neoplasm, consistent with a low-grade sarcoma. Pediatric cardiac sarcomas are rare in general, and this is the first reported case of a valvular low-grade myofibroblastic sarcoma presenting in a child.
PMID: 18160061 [PubMed - as supplied by publisher] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - December 29, 2007 Category: Cardiology Authors: Eisenstat J, Gilson T, Reimann J, Sampson B Tags: Cardiovasc Pathol Source Type: journals
Primary cardiac sarcoma: reports of two cases and a review of current literature
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We report the cases of two patients presenting with features of obstruction and embolism and a presumed diagnosis of left atrial myxoma. At operation they were unexpectedly found to have large tumours raising strong suspicions of malignancy. Due to the extensive involvement of intracardiac structures with little possibility of reconstruction together with poor general condition of the patient, debulking was deemed to be the only viable option. Subsequent histology confirmed the diagnosis of sarcoma in both patients. Surgery produced immediate and effective symptom relief. The first patient died four months after the operat...
Source: Journal of Cardiothoracic Surgery - July 24, 2007 Category: Cardiovascular & Thoracic Surgery Authors: Mohan P Devbhandari, Shaista Meraj, Mark T Jones, Isaac Kadir and Ben Bridgewater Source Type: journals
[CASE STUDIES] Intimal Cardiac Sarcoma in a Pregnant Woman
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A 29-year-old female patient in the 28th week of pregnancy was diagnosed with a cardiac tumor. We performed tumor excision and mitral valve replacement, and her baby was born successfully with cesarean section on the 9th day after cardiac surgery. After this event, 8 cycles of chemotherapy were administered. After 10 months, metastatic intimal sarcoma of the right ovary developed, and a right salpingo-oophorectomy and omentectomy was performed. However, the patient died of sudden onset of intractable ventricular fibrillation. (Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - January 23, 2007 Category: Cardiology Authors: Son, Sun, Jung, Park, Lee, Kim Source Type: journals
Cardiac autotransplantation for surgical resection of a primary malignant left ventricular tumor.
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We report the case of a patient who had a large, primary, intracavitary, left ventricular sarcoma that was successfully removed by cardiac explantation and ex vivo reconstruction with use of the cardiac autotransplantation technique. This is the 1st report describing the use of cardiac autotransplantation to surgically resect an intracavitary left ventricular malignancy.
PMID: 17215979 [PubMed - in process] (Source: Texas Heart Institute Journal)
Source: Texas Heart Institute Journal - January 12, 2007 Category: Cardiology Source Type: journals
[LETTERS TO THE EDITOR] Survival after radical resection of cardiac sarcomas
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(Source: European Journal of Cardio-Thoracic Surgery)
Source: European Journal of Cardio-Thoracic Surgery - December 1, 2006 Category: Cardiovascular & Thoracic Surgery Authors: Hoffmeier, A., Scheld, H. H., Klotz, S. Source Type: journals
Primary cardiac sarcoma in pregnancy: a case report.
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We report a pregnant woman at 27(+5) weeks gestation who was admitted to the hospital with acute-onset dyspnea. A mass was found on the left atrium by transthoracic echocardiography. Subsequently, the intracardiac mass was removed, and mitral valve replacement and modified DeVega tricuspid annuloplasty were performed. The patient was diagnosed with a undifferentiated sarcoma, and gave birth to a 1,230 g living baby boy by Caesarean section from preterm contraction at 29(+5) weeks gestation. The patient then received systemic chemotherapy. However, 10 months after the initial clinical onset, the patient suddenly died. Surge...
Source: J Korean Med Sci - October 19, 2006 Category: Journals (General) Source Type: journals
[CASE STUDIES] Malignant Peripheral Nerve Sheath Tumor of the Heart
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A 32-year-old man presented with dyspnea, chest pain, palpitations and ankle edema and was found to have a tumor involving the heart. This was diagnosed as malignant peripheral nerve sheath tumor, a rare sarcoma of the heart. Immunohistochemistry was utilized to establish the diagnosis. The details of the patient’s clinical course, and imaging findings with morphological and immunohistochemistry data are reported. (Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - September 27, 2006 Category: Cardiology Authors: Rahman, Cook, Ellis, O'Keefe Source Type: journals
[REVIEW PAPER] Primary Left Atrial Leiomyosarcoma: Literature Review and Lessons of a Case
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Primary cardiac sarcoma is an uncommon disease. In particular, leiomyosarcoma of cardiovascular origin is extremely rare. Half of all cardiac leiomyosarcomas are located in the left atrium. Due to the extreme rarity of left atrial leiomyosarcoma, there is no great experience in its management. This review includes a report of a case of left atrial leiomyosarcoma followed up over 45 months. The literature review examines the distribution of left atrial leiomyosarcoma, the physiological reasons for the tendency of cardiac leiomyosarcoma to be localized to the left atrial cavity, the clinical and physical appearance of this d...
Source: Asian Cardiovascular and Thoracic Annals - September 27, 2006 Category: Cardiology Authors: Malyshev, Safuanov, Gladyshev, Trushyna, Abramovskaya, Malyshev Source Type: journals
[REVIEWS] Primary cardiac sarcoma
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This article addresses these issues, deals with the surgically relevant modes of presentation, rather than the histopathology, and reviews the diagnosis and management options for the various sarcomas, categorized by the site and extent of cardiac involvement. Clinicians should be familiar with the presentation of these tumours and have a high index of suspicion, since the potential for long-term survival following resection does exist. Wide surgical resection remains the cornerstone of sarcoma therapy. Complete characterization of tumour extent using echocardiography and CT/MRI is mandatory to achieve this goal. Radical r...
Source: European Journal of Cardio-Thoracic Surgery - May 26, 2006 Category: Cardiovascular & Thoracic Surgery Authors: Shanmugam, G. Source Type: journals
Primary synovial sarcoma of the mitral valve.
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Primary cardiac synovial sarcoma is a rare malignancy, comprising approximately 5% of cardiac sarcomas and less than 0.1% of all primary cardiac tumors. Herein, we describe a synovial sarcoma arising on the anterior mitral leaflet in a 66-year-old man. The histopathologic diagnosis was supported by the immunohistochemical profile and the presence of the SYT-SSX1 fusion transcript identified by molecular genetic studies.
PMID: 16286044 [PubMed - indexed for MEDLINE] (Source: Cardiovascular Pathology)
Source: Cardiovascular Pathology - November 1, 2005 Category: Cardiology Authors: Miller DV, Deb A, Edwards WD, Zehr KJ, Oliveira AM Tags: Cardiovasc Pathol Source Type: journals
